@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XX82: (2018-01-02 )
MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGNGAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTVEENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAITLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRYGSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70..----.---..--.--..80-----..--.......90........100.......110........120.......130.......140........150.......160.......170.......180.......190.......200.......210.......220.......230----.---------.......240.......250---------........260......------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MNDV
L
T
L
E
N
L
H
H
T
F
EKGTINEN
H
V
L
KG
I
N
L
SLDPG
D
F
V
T
I
IGGNGA
G
K
S
T
L
L
N
S
IAG
T
F
SVDQ
G
Q
I
L
LNGKNI----
T
---
K
K
--
S
--
V
V
E
------
R
S
--
K
S
I
S
R
V
FQDPKLG
T
A
V
R
L
T
VEE
N
L
A
L
A
M
-KRGKKRGFFRGVKPQ
D
R
T
F
F
K
D
Q
L
V
R
L
NLG-LE
N
R
L
S
S
EIGLLSGG
Q
R
Q
A
I
T
L
L
M
A
T
LQRP
E
L
I
L
LDEHTAALDPATS
K
T
V
M
E
L
T
E
K
L
I
T
EQN
L
T
A
F
M
V
TH
D
M
E
D
A
I
R
YG
S
R
L
I
M
L
HQ
G
R
I
V
-----
V
---------
D
I
Q
Q
EEKQQL
T
V
P
Q
L
L
A
L
F
----------KQNSGTALKDD
Q
V
LLSS------------------------------------------------------------------------------------------
32
Fugue
72.27
25%
-27
- C1 -
-
1OXS
-
?
C:
[1-352]
M
V
R
-
I
I
V
K
N
V
S
K
V
F
K
K
G
---
K
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
D
R
L
V
----
A
SNG
K
L
--
I
--
V
P
P
------
E
D
--
R
K
I
G
M
V
F
Q
T
W
A
L
Y
P
--
N
L
T
A
F
E
N
I
A
F
P
L
-
T
N
-------
M
K
M
S
K
E
E
I
R
K
R
V
E
E
V
A
K
I
-
L
D
-
I
H
H
V
L
N
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
-----
Q
---------
V
G
K
P
E
D
L
Y
D
N
P
V
S
I
Q
V
A
S
L
IGEINELEGK
V
T
N
E
G
V
V
I
G
S
L
R
F
P
V
S
V
SSDRAIIGIRPEDVKLSKDVIKDDSWILVGKGKVKVIGYQGGLFRITITPLDSEEEIFTYSDHPIHSGEEVLVYVRKDKIKVFEK-----
57
HHSearch
71.26
35%
-37
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[2-228]
-
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
-----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
----
F
---
S
K
NT
N
--
L
P
V
------
R
E
--
R
R
L
G
Y
L
V
Q
E
G
V
--
L
F
P
H
L
T
V
Y
R
N
I
A
Y
G
L
-
G
N
G
K
G
R
------
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
--
G
-
I
S
E
L
A
G
R
Y
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
-----
Q
---------
T
A
S
P
H
E
L
Y
R
-------------------------------------------------------------------------------------------------------------------------------
35
Fugue
71.04
24%
-64
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
--
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
-
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
----
T
TLS
E
S
--
E
--
L
T
K
------
A
R
--
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
--
S
R
T
V
F
G
N
V
A
L
P
L
-
E
L
D
-------
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
-
V
G
-
L
G
D
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
EQDTV
S
---------
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
----------
H
L
D
I
P
E
D
Y
Q
E
R
L
Q
A
E
P
F
TDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV-------------
8
PsiBlast_PDB
70.19
34%
-55
- C1 -
-
3FVQ
2
FBPC_NEIG1
A:
[2-223]
-
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
-----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
----
F
---
S
K
--
N
T
N
L
P
V
------
R
E
--
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
--
H
L
T
V
Y
R
N
I
A
Y
G
L
-
G
N
G
K
G
R
------
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
A
G
R
Y
P
H
E
---
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
70.09
24%
-99
- C1 -
-
1Z47
-
?
A:
[11-355]
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P
G
G
----
A
R
S
V
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
----
T
---
D
L
--
P
--
P
Q
K
------
R
N
----
V
G
L
V
F
Q
N
Y
A
L
F
Q
--
H
M
T
V
Y
D
N
V
S
F
G
L
-
R
E
K
R
V
--------
P
K
D
E
M
D
A
R
V
R
E
L
L
R
F
M
R
-
L
E
S
Y
A
N
R
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
-----
Q
---------
F
G
T
P
E
E
V
Y
E
K
P
G
T
L
F
V
A
S
F
IGE-------
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
21
PsiBlast_CBE
69.29
34%
-56
- C1 -
-
3FVQ
2
FBPC_NEIG1
B:
[2-218]
-
T
A
A
L
H
I
G
H
L
S
K
S
F
Q
N
-----
T
P
V
L
N
D
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
K
T
I
----
F
---
S
K
--
N
TN
L
P
V
------
R
E
--
R
R
L
G
Y
L
V
Q
E
G
V
L
F
P
--
H
L
T
V
Y
R
N
I
A
Y
G
L
-
G
N
G
K
G
R
------
T
A
Q
E
R
Q
R
I
E
A
M
L
E
L
T
G
I
S
E
L
A
G
R
Y
P
H
E
---
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
N
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
A
D
R
I
A
V
M
K
Q
G
R
I
L
-------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
68.48
29%
-58
- C1 -
-
4U00
1
?
A:
[3-224]
--
P
I
I
R
I
R
N
L
H
K
W
F
--
G
P
L
---
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
----
K
D--
D
R
--
A
--
L
R
E
------
I
R
--
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
-
M
R
V
R
R
-------
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
-
I
L
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
---------
E
G
R
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
67.98
29%
-64
- C1 -
-
4U02
-
?
A:
[1-224]
M
E
P
I
I
R
I
R
N
L
H
K
W
F
--
G
P
L
---
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
L
S
V
----
K
D--
D
R
--
A
--
L
R
E
------
I
R
--
R
E
V
G
M
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
T
L
A
P
-
M
R
V
R
R
-------
W
P
R
E
K
A
E
K
K
A
L
E
L
L
E
R
V
G
-
I
L
D
Q
A
R
K
Y
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
-
A
Q
G
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-----
E
---------
E
G
R
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
63.33
34%
-14
- C1 -
-
4YMU
1
?
J:
[15-222]
----------------------
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
----
N
NG-
K
V
--
N
--
I
N
K
------
V
R
--
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
--
H
L
T
A
I
E
N
I
T
L
A
P
-
V
K
V
K
K
M
N
-----
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
--
L
D
K
K
D
Q
Y
P
I
K
L
-
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
---------
E
G
T
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
63.02
28%
-23
- C1 -
-
4MKI
2
ECFA2_CALS4
B:
[7-258]
----
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
G
I
D
I
----
T
---
D
K
--
K
--
V
S
L
------
K
D
I
R
K
Q
V
G
L
V
F
Q
Y
P
E
Y
Q
-----
L
F
E
E
T
V
F
K
D
I
-
A
F
G
P
S
N
L
G
L
S
E
E
E
V
K
E
R
V
Y
E
A
M
E
I
V
G
I
S
K
E
-
L
A
D
K
S
P
F
E
---
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
K
E
I
H
D
K
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
-----
L
I
G
T
P
R
E
V
F
R
E
A
E
R
L
E
K
I
G
L
S
V
P
Q
I
T
S
L
A
----------
R
E
---------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
62.42
34%
-14
- C1 -
-
4YMU
1
?
A:
[15-222]
----------------------
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
----
N
NG-
K
V
--
N
--
I
N
K
------
V
R
--
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
--
H
L
T
A
I
E
N
I
T
L
A
P
-
V
K
V
K
K
M
N
-----
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
--
L
D
K
K
D
Q
Y
P
I
K
L
-
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
---------
E
G
T
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
62.22
32%
11
- C1 -
-
2PCL
5
LOLD_AQUAE
A:
[2-223]
-
A
E
I
L
R
A
E
N
I
-----
K
K
V
I
R
G
Y
E
I
L
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
D
YTN
E
---
K
E
--
L
--
S
L
L
------
R
N
--
R
K
L
G
F
V
F
Q
F
H
Y
L
--
I
P
E
L
T
A
L
E
N
V
I
V
P
M
L
K
M
G
---------
K
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
-
L
G
D
K
L
S
R
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
-
I
N
E
G
G
T
S
I
V
M
V
T
H
E
R
E
L
A
-
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
-----
G
---------
E
I
T
R
------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
61.86
31%
4
- C1 -
-
1L2T
3
Y796_METJA
B:
[1-228]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
-
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--
N
I
----
K
---
T
N
--
D
--
L
D
D
DELTKI
R
R
--
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
-
I
F
-
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
-
F
A
N
H
K
P
N
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
------------------
E
V
E
R
E
E
K
---------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
61.80
34%
-8
- C1 -
-
4YMS
-
?
J:
[15-222]
----------------------
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
----
N
NG-
K
V
--
N
--
I
N
K
------
V
R
--
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
--
H
L
T
A
I
E
N
I
T
L
A
P
-
V
K
V
K
K
M
N
-----
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
--
L
D
K
K
D
Q
Y
P
I
K
L
-
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
---------
E
G
T
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
61.39
31%
2
- C1 -
-
1L2T
3
Y796_METJA
A:
[1-228]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
-
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--
N
I
----
K
---
T
N
--
D
--
L
D
D
D
E
L
T
K
I
R
R
--
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
-
I
F
-
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
-
F
A
N
H
K
P
N
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
------------------
E
V
E
R
E
E
K
---------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
61.36
31%
-2
- C1 -
-
3TIF
4
Y796_METJA
A:
[1-228]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
-
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--
N
I
----
K
---
T
N
--
D
--
L
D
D
D
E
L
T
K
I
R
R
--
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
-
I
-
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
-
F
A
N
H
K
P
N
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
------------------
E
V
E
R
E
E
K
---------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
61.07
34%
-17
- C1 -
-
4YMV
1
?
A:
[15-222]
----------------------
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
----
N
NG-
K
V
--
N
--
I
N
K
------
V
R
--
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
--
H
L
T
A
I
E
N
I
T
L
A
P
-
V
K
V
K
K
M
N
-----
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
--
L
D
K
K
D
Q
Y
P
I
K
L
-
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
---------
E
G
T
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
61.05
25%
-110
- C1 -
-
4AYT
1
ABCBA_HUMAN
A:
[341-567]
---
A
L
E
F
K
N
V
H
F
A
Y
P
A
R
--
P
E
V
P
I
F
Q
D
F
S
L
S
I
P
S
G
S
V
T
A
L
V
G
P
S
G
S
G
K
S
T
V
L
S
L
L
L
R
L
Y
D
P
A
S
G
T
I
S
L
D
G
H
D
I
----
R
---
Q
L
--
N
--
P
V
W
------
L
R
--
S
K
I
G
T
V
S
Q
E
P
I
---
L
F
S
C
S
I
A
E
N
I
A
Y
G
A
-
D
D
P
S
S
V
T
A
E
E
I
Q
R
V
A
E
V
A
N
A
V
A
F
I
R
N
F
P
Q
G
-
F
N
T
V
V
G
E
K
G
V
L
L
S
G
G
Q
K
Q
R
I
A
I
A
R
A
L
L
K
N
P
K
I
L
L
L
D
E
A
T
S
A
L
D
A
E
N
E
Y
L
V
Q
E
A
L
D
R
L
M
--
D
G
R
T
V
L
V
I
A
H
R
L
S
T
I
-
K
N
A
N
M
V
A
V
L
D
Q
G
K
I
T
-----
E
---------
Y
G
K
H
E
E
----------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
60.67
34%
-10
- C1 -
-
4YMV
1
?
J:
[15-222]
----------------------
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
----
N
NG-
K
V
--
N
--
I
N
K
------
V
R
--
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
--
H
L
T
A
I
E
N
I
T
L
A
P
-
V
K
V
K
K
M
N
-----
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
--
L
D
K
K
D
Q
Y
P
I
K
L
-
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
-----
E
---------
E
G
T
P
E
E
----------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
60.55
31%
0
- C1 -
-
3TIF
4
Y796_METJA
B:
[1-228]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
-
E
I
I
Y
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--
N
I
----
K
---
T
N
--
D
--
L
D
D
DELTKI
R
R
--
D
K
I
G
F
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
-
I
-
F
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
-
F
A
N
H
K
P
N
Q
---
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
G
E
R
I
I
Y
L
K
D
G
------------------
E
V
E
R
E
E
K
---------------------------------------------------------------------------------------------------------------------------------