@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XXI4: (2018-01-04 )
MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNEETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIANFETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTPEDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQVNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEEAFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS
Atome Classification :
(20 SA)
.........10........20........-30.........40........50........60..-......-70.........80........90........100.......110.......120.......130--------.......140.......150.......160.......170...-....180.......190.......200.......210.......220.......230.......240.......250......--.260.......-270.......280--.......290.......300......-
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
S
K
I
L
V
F
GHQNP
D
T
D
A
I
G
A
A
I
A
F
S
H
L
Q
N
E
-L-GKET
E
A
V
A
LGTPNE
E
T
Q
Y
A
L
D
HFQLSA
P
R
V
V
E
S-AKAENA-
D
-
V
M
L
V
D
H
N
E
F
Q
Q
S
I
S
D
ISE
V
N
I
L
A
V
VDHHRIANFETANP
L
Y
Y
RAEPVG
C
T
S
T
I
I
L
K
L
YKENQV--------T
I
P
K
E
I
A
G
I
M
L
S
A
I
I
S
D
T
L
L
FKSPTCTP
E
D
E
A
A
A
K
E
L
A
A
I
A
EV-D
L
N
T
Y
G
L
E
M
L
KAGTNLSDK
S
A
A
V
L
L
D
LDAKSFPMGSS
N
V
R
I
A
Q
V
N
T
V
D
L
N
E
V
M
D
R
Q
A
E
L
E
A
A
M
E
D
E
MKANG
Y
D
L
F
V
L
V
V
T
N
IL--DSDS
E
L
L
V
AGK-
G
K
E
K
V
E
E
A
F
Q
T
TL--TN
N
R
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
Q
L
T
A
VFS-
8
PsiBlast_PDB
91.90
64%
-117
- C3 -
-
1K23
-
PPAC_BACSU
A:
[3-304]
--
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
6
PsiBlast_PDB
90.71
64%
-93
- C3 -
-
2IW4
1
PPAC_BACSU
A:
[2-304]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
Q
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
27
HHSearch
90.52
64%
-90
- C3 -
-
2IW4
5
PPAC_BACSU
B:
[1-308]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
Q
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
D
A
M
A
-
24
PsiBlast_CBE
90.32
64%
-93
- C3 -
-
2HAW
6
PPAC_BACSU
B:
[1-304]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
25
PsiBlast_CBE
90.28
64%
-93
- C3 -
-
1WPM
2
PPAC_BACSU
B:
[1-304]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
26
PsiBlast_CBE
90.16
64%
-90
- C3 -
-
2IW4
5
PPAC_BACSU
B:
[1-304]
M
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
Q
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
4
PsiBlast_PDB
90.07
64%
-93
- C3 -
-
1WPM
1
PPAC_BACSU
A:
[2-304]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
5
PsiBlast_PDB
89.90
64%
-94
- C3 -
-
2HAW
2
PPAC_BACSU
A:
[2-304]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
A
D
L
S
K
K
T
V
E
E
L
I
S
L
D
A
K
E
F
T
L
G
S
K
K
V
E
I
A
Q
V
N
T
V
D
I
E
D
V
K
K
R
Q
A
E
L
E
A
V
I
S
K
V
V
A
E
K
N
L
D
L
F
L
L
V
I
T
D
I
L
--
E
N
D
S
L
A
L
A
I
G
N
-
E
A
A
K
V
E
K
A
F
N
V
T
L
--
E
N
N
T
A
L
L
K
G
V
V
S
R
K
K
Q
V
V
P
V
L
T
-----
7
PsiBlast_PDB
79.61
62%
-1
- C3 -
-
1I74
-
PPAC_STRMU
A:
[1-308]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
M
A
Y
A
Y
L
K
R
Q
-
L
-
G
V
D
A
Q
A
V
A
L
G
N
P
N
E
E
T
A
F
V
L
D
Y
F
G
I
Q
A
P
P
V
V
K
S
-
A
Q
A
E
G
A
K
Q
-
V
I
L
T
D
H
N
E
F
Q
Q
S
I
A
D
I
R
E
V
E
V
V
E
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
L
Y
K
E
N
G
V
--------
A
I
P
K
E
I
A
G
V
M
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
P
A
V
A
E
D
L
A
K
I
A
G
V
-
D
L
Q
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
T
A
A
Q
L
V
D
I
D
A
K
T
F
E
L
N
G
S
Q
V
R
V
A
Q
V
N
T
V
D
I
N
E
V
L
E
R
Q
N
E
I
E
E
A
I
K
A
S
Q
A
A
N
G
Y
S
D
F
V
L
M
I
T
D
I
L
--
N
S
N
S
E
I
L
A
L
G
N
-
N
T
D
K
V
E
A
A
F
N
F
T
L
--
K
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
-
1
PsiBlast_PDB
77.53
61%
18
- C3 -
-
1WPP
-
PPAC_STRGC
A:
[2-310]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
Y
-
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
-
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
S
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
G
V
--------
A
V
P
K
E
I
A
G
L
M
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
V
I
A
P
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
--
N
S
N
S
E
I
L
A
I
G
S
-
N
M
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
-
51
Fugue
77.47
62%
22
- C3 -
-
1K20
1
PPAC_STRGC
A:
[1-310]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
-
A
Y
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
E
Q
-
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
--------
A
V
S
K
E
I
A
G
L
M
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
--
N
S
N
S
E
I
L
A
I
G
S
-
N
M
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
A
23
PsiBlast_CBE
76.80
61%
21
- C3 -
-
1K20
2
PPAC_STRGC
B:
[1-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
Y
-
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
-
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
--------
A
V
S
K
E
I
A
G
L
M
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
--
N
S
N
S
E
I
L
A
I
G
S
-
N
M
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
-
3
PsiBlast_PDB
76.76
61%
22
- C3 -
-
1K20
1
PPAC_STRGC
A:
[1-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
Y
-
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
-
A
K
A
E
G
A
-
E
Q
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
--------
A
V
S
K
E
I
A
G
L
M
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
--
N
S
N
S
E
I
L
A
I
G
S
-
N
M
D
K
V
E
A
A
F
N
F
V
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
F
N
-
2
PsiBlast_PDB
76.71
61%
24
- C3 -
-
2ENX
2
PPAC_STRA5
A:
[1-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
V
A
F
A
Y
L
A
K
E
A
W
-
G
L
D
T
E
A
V
A
L
G
T
P
N
E
E
T
A
Y
V
L
D
Y
F
G
V
Q
A
P
R
V
V
E
S
-
A
K
A
E
G
V
-
E
T
V
I
L
T
D
H
N
E
F
Q
Q
S
I
S
D
I
K
D
V
T
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
N
G
V
--------
S
V
P
K
E
L
A
G
L
L
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
I
P
V
A
K
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
E
M
L
K
A
G
T
N
L
S
S
K
T
A
A
E
L
I
D
I
D
A
K
T
F
E
L
N
G
E
A
V
R
V
A
Q
V
N
T
V
D
I
N
D
I
L
A
R
Q
E
E
I
E
V
A
I
Q
E
A
I
V
T
E
G
Y
S
D
F
V
L
M
I
T
D
I
V
--
N
S
N
S
E
I
L
A
L
G
S
-
N
M
A
K
V
E
A
A
F
E
F
T
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
Y
N
-
40
HHSearch
75.87
70%
-123
- C3 -
-
1WPN
-
PPAC_BACSU
B:
[2-187]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
-------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
75.76
61%
21
- C3 -
-
2ENX
2
PPAC_STRA5
A:
[1-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
V
A
F
A
Y
L
A
K
E
A
W
-
G
L
D
T
E
A
V
A
L
G
T
P
N
E
E
T
A
Y
V
L
D
Y
F
G
V
Q
A
P
R
V
V
E
S
A
K
A
E
G
V
E
-
T
-
V
I
L
T
D
H
N
E
F
Q
Q
S
I
S
D
I
K
D
V
T
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
N
G
V
--------
S
V
P
K
E
L
A
G
L
L
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
I
P
V
A
K
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
E
M
L
K
A
G
T
N
L
S
S
K
T
A
A
E
L
I
D
I
D
A
K
T
F
E
L
N
G
E
A
V
R
V
A
Q
V
N
T
V
D
I
N
D
I
L
A
R
Q
E
E
I
E
V
A
I
Q
E
A
I
V
T
E
G
Y
S
D
F
V
L
M
I
T
D
I
V
--
N
S
N
S
E
I
L
A
L
G
S
-
N
M
A
K
V
E
A
A
F
E
F
T
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
Y
N
-
22
PsiBlast_CBE
75.51
61%
22
- C3 -
-
2ENX
2
PPAC_STRA5
B:
[1-309]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
V
A
F
A
Y
L
A
K
E
A
W
-
G
L
D
T
E
A
V
A
L
G
T
P
N
E
E
T
A
Y
V
L
D
Y
F
G
V
Q
A
P
R
V
V
E
S
-
A
K
A
E
G
V
-
E
T
V
I
L
T
D
H
N
E
F
Q
Q
S
I
S
D
I
K
D
V
T
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
N
G
V
--------
S
V
P
K
E
L
A
G
L
L
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
A
S
D
I
P
V
A
K
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
E
M
L
K
A
G
T
N
L
S
S
K
T
A
A
E
L
I
D
I
D
A
K
T
F
E
L
N
G
E
A
V
R
V
A
Q
V
N
T
V
D
I
N
D
I
L
A
R
Q
E
E
I
E
V
A
I
Q
E
A
I
V
T
E
G
Y
S
D
F
V
L
M
I
T
D
I
V
--
N
S
N
S
E
I
L
A
L
G
S
-
N
M
A
K
V
E
A
A
F
E
F
T
L
--
E
N
N
H
A
F
L
A
G
A
V
S
R
K
K
Q
V
V
P
Q
L
T
E
S
Y
N
-
9
PsiBlast_PDB
74.81
69%
-117
- C3 -
-
1WPN
-
PPAC_BACSU
A:
[2-188]
-
E
K
I
L
I
F
G
H
Q
N
P
D
T
D
T
I
C
S
A
I
A
Y
A
D
L
K
N
K
-
L
-
G
F
N
A
E
P
V
R
L
G
Q
V
N
G
E
T
Q
Y
A
L
D
Y
F
K
Q
E
S
P
R
L
V
E
T
-
A
A
N
E
V
N
-
G
-
V
I
L
V
D
H
N
E
R
Q
Q
S
I
K
D
I
E
E
V
Q
V
L
E
V
I
D
H
H
R
I
A
N
F
E
T
A
E
P
L
Y
Y
R
A
E
P
V
G
C
T
A
T
I
L
N
K
M
Y
K
E
N
N
V
--------
K
I
E
K
E
I
A
G
L
M
L
S
A
I
I
S
D
S
L
L
F
K
S
P
T
C
T
D
Q
D
V
A
A
A
K
E
L
A
E
I
A
G
V
-
D
A
E
E
Y
G
L
N
M
L
K
A
G
------------------------------------------------------------------------------------------------------------------------------
30
HHSearch
71.97
57%
10
- C3 -
-
1K20
2
PPAC_STRGC
B:
[1-308]
-
S
K
I
L
V
F
G
H
Q
N
P
D
S
D
A
I
G
S
S
Y
A
F
A
Y
L
A
R
E
A
Y
-
G
L
D
T
E
A
V
A
L
G
E
P
N
E
E
T
A
F
V
L
D
Y
F
G
V
A
A
P
R
V
I
T
S
A
K
A
E
G
A
E
-
Q
-
V
I
L
T
D
H
N
E
F
Q
Q
S
V
A
D
I
A
E
V
E
V
Y
G
V
V
D
H
H
R
V
A
N
F
E
T
A
N
P
L
Y
M
R
L
E
P
V
G
S
A
S
S
I
V
Y
R
M
F
K
E
H
S
V
--------
A
V
S
K
E
I
A
G
L
M
L
S
G
L
I
S
D
T
L
L
L
K
S
P
T
T
H
P
T
D
K
A
I
A
P
E
L
A
E
L
A
G
V
-
N
L
E
E
Y
G
L
A
M
L
K
A
G
T
N
L
A
S
K
S
A
E
E
L
I
D
I
D
A
K
T
F
E
L
N
G
N
N
V
R
V
A
Q
V
N
T
V
D
I
A
E
V
L
E
R
Q
A
E
I
E
A
A
I
E
K
A
I
A
D
N
G
Y
S
D
F
V
L
M
I
T
D
I
I
NS
N
S
E
I
L
A
I
G
S
N
M
D
K
V
E
A
A
F
N
F
V
L
E
N
N
HA
F
L
A
G
A
V
S
-----
R
K
K
Q
V
V
P
Q
L
T
E
S
F
--
10
PsiBlast_PDB
64.01
38%
10
- C3 -
-
2EB0
-
PPAC_METJA
A:
[4-306]
-----
V
V
G
H
K
N
P
D
T
D
S
I
A
S
A
I
V
L
A
Y
F
L
D
-------
C
Y
P
A
R
L
G
D
I
N
P
E
T
E
F
V
L
R
K
F
G
V
M
E
P
E
L
I
E
S
-
A
K
G
K
---
E
-
I
I
L
V
D
H
S
E
K
S
Q
S
F
D
D
L
E
E
G
K
L
I
A
I
I
D
H
H
K
V
G
-
L
T
T
T
E
P
I
L
Y
Y
A
K
P
V
G
S
T
A
T
V
I
A
E
L
Y
F
K
D
A
I
DLIGGKK
K
E
L
K
P
D
L
A
G
L
L
L
S
A
I
I
S
D
T
V
L
F
K
S
P
T
T
T
D
L
D
K
E
M
A
K
K
L
A
E
I
A
G
I
S
N
I
E
E
F
G
M
E
I
L
K
A
K
S
V
V
G
K
L
K
P
E
E
I
I
N
M
D
F
K
N
F
D
F
N
G
K
K
V
G
I
G
Q
V
E
V
I
D
V
S
E
V
E
S
K
K
E
D
I
Y
K
L
L
E
E
K
L
K
N
E
G
Y
D
L
I
V
F
L
I
T
D
I
M
--
K
E
G
S
E
A
L
V
V
G
--
N
K
E
M
F
E
K
A
F
---
V
--
E
G
N
S
V
F
L
E
G
V
M
S
R
K
K
Q
V
V
P
P
L
E
R
A
Y
N
-