@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XY18: (2018-01-07 )
MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIFEHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAKPFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQIRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKFVAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAPKMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAYVVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDELASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE
Atome Classification :
(24 SA)
.........10........20........30........40........50........60........70-.-..--......80........90........100.......110.......120.......130.......140.......150.......-160........170.......180.......190.......200.......210.......220-.--.......230.......240.......250.......260.......270.....-.-.280.......290.......300-.........310.......320.......330-.........340.......350....------...----360...--.----...-----370.......380.......390.......400....--...410.......420.......430
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSFQRPKGTNDILPGE
S
E
K
W
Q
F
V
E
E
T
A
R
L
L
F
R
DYQ
Y
N
E
MR
T
P
I
F
E
H
Y
E
V
I
S
R
SVGD
T
T
D
I
V
S
K
E
M
Y
D
F
YD--K-GE--
R
H
V
T
LRPEG
T
A
P
I
V
R
S
F
V
E
H
KLFG
P
E
Y
A
K
P
F
K
T
F
YMGPMFRYERPQK
G
R
L
R
Q
F
H
Q
I
G
V
E
AFGSENPA
T
D
V
E
S
M
V
M
A
L
D
F
F
K
QLG
I
T
-
Q
-
I
R
L
V
I
N
SLG
D
K
E
T
R
Q
A
Y
R
Q
A
L
I
D
Y
LLP
F
E
S
E
L
S
E
D
S
K
R
R
LHEN
P
L
R
V
LDSKDKR
D
Q
K
F
V
AE--A--
P
S
I
L
D
Y
L
S
E
P
A
Q
K
H
F
D
T
V
V
S
M
L
D
A
LAV
P
Y
EIDS
N
M
V
R
G
L
D
Y
Y
T
H
T
I
F
E
I
M
SDAPK-M-GA
Q
A
T
I
CAGG
R
Y
D
N
L
V
E
E
LGGP---STPG
F
G
F
A
M
G
I
E
R
L
L
L
TMEAE
E
V
V
IPAFNE---L
D
A
Y
V
V
A
LGDET
N
I
E
A
L
K
V
V
Q
A
I
R
NF------GFS----A
D
R
D
F
M
--
N
----
R
K
A
-----K
A
Q
FKTADKAN
A
K
L
V
L
V
IGE
D
E
LASQ
T
I
N
V
K
A
MASRK--EKSF
P
L
E
E
I
Y
E
H
F
D
E
V
Y
D
E
MTLFE
43
HHSearch
90.20
47%
-65
- C2 -
-
1QE0
-
SYH_STAAU
A:
[2-420]
--
I
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I
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R
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P
E
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M
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N
Y
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P
I
F
E
S
T
D
L
F
A
R
-----------
E
M
Y
T
F
K
D
--
K
-
G
D
--
R
S
I
T
L
R
P
E
G
T
A
A
V
V
R
S
Y
I
E
H
K
M
Q
G
-
N
P
N
Q
P
I
K
L
Y
Y
N
G
P
M
F
R
Y
-------
Y
R
Q
F
N
Q
F
G
V
E
A
I
G
A
E
N
P
S
V
D
A
E
V
L
A
M
V
M
H
I
Y
Q
S
F
G
L
K
-
H
-
L
K
L
V
I
N
S
V
G
D
M
A
S
R
K
E
Y
N
E
A
L
V
K
H
F
E
P
V
I
H
E
F
C
S
D
C
Q
S
R
L
H
T
D
P
M
R
I
L
------------
T
--
A
--
P
R
I
T
D
F
L
N
E
E
S
K
A
Y
Y
E
Q
V
K
A
Y
L
D
D
L
G
I
P
Y
T
E
D
P
N
L
V
R
G
L
D
Y
Y
T
H
T
A
F
E
L
M
M
D
N
P
N
Y
D
-
G
A
I
T
T
L
C
G
G
G
R
Y
N
G
L
L
E
L
L
D
G
P
---
S
E
T
G
I
G
F
A
L
S
I
E
R
L
L
L
A
L
E
E
E
G
I
E
L
D
I
E
E
N
---
L
D
L
F
I
V
T
M
G
D
Q
A
D
R
Y
A
V
K
L
L
N
H
L
R
H
N
------
G
I
K
----
A
D
K
D
Y
L
--
Q
----
R
K
I
-----
K
G
Q
M
K
Q
A
D
R
L
G
A
K
F
T
I
V
I
G
D
Q
E
L
E
N
N
K
I
D
V
K
N
M
T
T
G
E
--
S
E
T
I
E
L
D
A
L
V
E
Y
F
K
K
---------
1
PsiBlast_PDB
90.13
46%
-71
- C2 -
-
1QE0
-
SYH_STAAU
A:
[5-418]
-----
P
R
G
T
Q
D
I
L
P
E
D
S
K
K
W
R
Y
I
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Q
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F
Y
N
Y
K
E
I
R
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P
I
F
E
S
T
D
L
F
A
R
-----------
E
M
Y
T
F
K
D
--
K
-
G
D
--
R
S
I
T
L
R
P
E
G
T
A
A
V
V
R
S
Y
I
E
H
K
M
Q
G
N
P
-
N
Q
P
I
K
L
Y
Y
N
G
P
M
F
R
Y
-------
Y
R
Q
F
N
Q
F
G
V
E
A
I
G
A
E
N
P
S
V
D
A
E
V
L
A
M
V
M
H
I
Y
Q
S
F
G
L
K
-
H
-
L
K
L
V
I
N
S
V
G
D
M
A
S
R
K
E
Y
N
E
A
L
V
K
H
F
E
P
V
I
H
E
F
C
S
D
C
Q
S
R
L
H
T
D
P
M
R
I
L
------------
T
--
A
--
P
R
I
T
D
F
L
N
E
E
S
K
A
Y
Y
E
Q
V
K
A
Y
L
D
D
L
G
I
P
Y
T
E
D
P
N
L
V
R
G
L
D
Y
Y
T
H
T
A
F
E
L
M
M
D
N
P
N
-
Y
D
G
A
I
T
T
L
C
G
G
G
R
Y
N
G
L
L
E
L
L
D
G
P
---
S
E
T
G
I
G
F
A
L
S
I
E
R
L
L
L
A
L
E
E
E
G
I
E
L
D
I
E
E
N
---
L
D
L
F
I
V
T
M
G
D
Q
A
D
R
Y
A
V
K
L
L
N
H
L
R
H
N
------
G
I
K
----
A
D
K
D
Y
L
--
Q
----
R
K
I
-----
K
G
Q
M
K
Q
A
D
R
L
G
A
K
F
T
I
V
I
G
D
Q
E
L
E
N
N
K
I
D
V
K
N
M
T
T
G
E
--
S
E
T
I
E
L
D
A
L
V
E
Y
F
-----------
48
HHSearch
86.29
43%
-10
- C2 -
-
4E51
1
SYH_BURTA
A:
[32-460]
--
L
T
G
V
K
G
M
N
D
I
L
P
Q
D
A
G
L
W
E
F
F
E
A
T
V
K
S
L
L
R
A
Y
G
Y
Q
N
I
R
T
P
I
V
E
H
T
P
L
F
T
R
G
I
G
E
V
T
D
I
V
E
K
E
M
Y
S
F
V
D
--
A
L
N
G
--
E
N
L
T
L
R
P
E
N
T
A
A
V
V
R
A
A
I
E
H
N
M
---
L
Y
D
G
P
K
R
L
W
Y
I
G
P
M
F
R
H
E
R
P
---
R
Y
R
Q
F
H
Q
V
G
V
E
A
L
G
F
A
G
P
D
A
D
A
E
I
V
M
M
C
Q
R
L
W
E
D
L
G
L
T
-
G
-
I
K
L
E
I
N
S
L
G
L
A
E
E
R
A
A
H
R
V
E
L
I
K
Y
L
E
Q
H
A
D
K
L
D
D
D
A
Q
R
R
L
Y
T
N
P
L
R
V
L
D
T
K
N
P
A
L
Q
E
I
V
R
N
--
A
--
P
K
L
I
D
F
L
G
D
V
S
R
A
H
F
E
G
L
Q
R
L
L
K
A
N
N
V
P
F
T
I
N
P
R
L
V
R
G
L
D
Y
Y
N
L
T
V
F
E
W
V
T
D
K
--------
G
T
V
A
A
G
G
R
Y
D
P
L
I
E
Q
L
G
G
K
---
P
T
A
A
C
G
W
A
M
G
I
E
R
I
L
E
L
L
K
E
E
H
L
-
V
P
E
Q
E
G
---
V
D
V
Y
V
V
H
Q
G
D
A
A
R
E
Q
A
F
I
V
A
E
R
L
R
D
T
------
G
L
D
----
V
I
L
H
C
S
--
A
DGAG
A
S
F
-----
K
S
Q
M
K
R
A
D
A
S
G
A
A
F
A
V
I
F
G
E
D
E
V
T
N
G
T
A
S
V
K
P
L
--
S
V
--
Q
Q
S
V
P
V
E
S
L
T
E
F
L
I
N
A
M
V
A
-----
41
HHSearch
84.54
42%
-20
- C2 -
-
1ADJ
1
SYH_THET8
C:
[2-420]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
K
--
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
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F
H
Q
V
N
Y
E
A
L
G
S
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P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
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K
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D
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A
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A
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--
L
GV
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H
E
E
I
----
G
A
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A
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G
G
G
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R
Y
D
G
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E
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L
G
G
P
---
R
V
P
G
V
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A
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A
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G
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K
G
---
P
D
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Y
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E
A
V
A
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Y
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A
E
A
L
R
P
-------
R
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
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R
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A
A
F
A
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E
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A
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--
Q
V
R
L
S
R
E
E
V
P
G
Y
L
L
Q
A
L
-------
47
HHSearch
83.00
43%
-16
- C2 -
-
4E51
1
SYH_BURTA
B:
[32-460]
--
L
T
G
V
K
G
M
N
D
I
L
P
Q
D
A
G
L
W
E
F
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E
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------
D
I
V
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K
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--
E
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A
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A
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I
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H
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M
---
L
Y
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G
P
K
R
L
W
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M
F
R
H
E
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-----
Y
R
Q
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Q
V
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A
L
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A
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P
D
A
D
A
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C
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L
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-
G
-
I
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E
E
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A
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V
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Y
L
E
Q
H
A
D
------
Q
R
R
L
Y
T
N
P
L
R
V
L
----
P
A
L
Q
E
I
V
R
N
--
A
--
P
K
L
I
D
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L
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D
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A
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Y
Y
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---------
G
T
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A
A
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Q
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---
P
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A
A
C
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W
A
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I
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E
E
H
L
-
V
P
E
Q
E
G
---
V
D
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V
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Q
G
D
A
A
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E
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A
F
I
V
A
E
R
L
R
D
T
------
G
L
D
----
V
I
L
H
C
S
--
A
DGAG
A
S
F
-----
K
S
Q
M
K
R
A
D
A
S
G
A
A
F
A
V
I
F
G
E
D
E
V
T
N
G
T
A
S
V
K
P
L
--
S
V
--
Q
Q
S
V
P
V
E
S
L
T
E
F
L
I
N
A
M
V
A
-----
35
PsiBlast_CBE
82.62
41%
-17
- C2 -
-
1ADY
1
SYH_THET8
C:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
LG
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
42
HHSearch
82.49
42%
-20
- C2 -
-
1H4V
-
SYH_THET2
B:
[2-420]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
------
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
K
--
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
----
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
--
L
GV
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
----------
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
-------
R
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
P
G
Y
L
L
Q
A
L
-------
34
PsiBlast_CBE
82.47
41%
-16
- C2 -
-
1ADY
1
SYH_THET8
D:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
LG
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
37
PsiBlast_CBE
82.39
41%
-23
- C2 -
-
1ADJ
1
SYH_THET8
D:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
LG
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
36
PsiBlast_CBE
82.27
41%
-16
- C2 -
-
1ADY
1
SYH_THET8
B:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
LG
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
8
PsiBlast_PDB
82.24
41%
-15
- C2 -
-
1ADY
1
SYH_THET8
A:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
L
G
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
7
PsiBlast_PDB
82.22
41%
-21
- C2 -
-
1ADJ
1
SYH_THET8
A:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
L
G
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
45
HHSearch
81.79
42%
-32
- C2 -
-
1KMM
1
SYH_ECOLI
C:
[5-423]
--
I
Q
A
I
R
G
M
N
D
Y
L
P
G
E
T
A
I
W
Q
R
I
E
G
T
L
K
N
V
L
G
S
Y
G
Y
S
E
I
R
L
P
I
V
E
Q
T
P
L
F
K
R
A
I
G
E
V
T
D
V
V
E
K
E
M
Y
T
F
E
D
--
R
-
N
G
--
D
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
G
I
E
H
G
L
L
---
Y
N
Q
E
Q
R
L
W
Y
I
G
P
M
F
R
H
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
L
G
C
E
V
F
G
L
Q
G
P
D
I
D
A
E
L
I
M
L
T
A
R
W
W
R
A
L
G
I
S
E
H
-
V
T
L
E
L
N
S
I
G
S
L
E
A
R
A
N
Y
R
D
A
L
V
A
F
L
E
Q
H
--------------------------------------
P
A
L
G
D
Y
L
D
E
E
S
R
E
H
F
A
G
L
C
K
L
L
E
S
A
G
I
A
Y
T
V
N
Q
R
L
V
R
G
L
D
Y
Y
N
R
T
V
F
E
W
V
T
N
S
L
----
G
S
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
E
Q
L
G
G
R
---
A
T
P
A
V
G
F
A
M
G
L
E
R
L
V
L
L
V
Q
A
V
N
P
E
F
K
A
D
P
V
---
V
D
I
Y
L
V
A
S
G
A
D
T
Q
S
A
A
M
A
L
A
E
R
L
R
D
E
------
L
P
G
----
V
K
L
M
T
N
H
G
G
----
G
N
F
-----
K
K
Q
F
A
R
A
D
K
W
G
A
R
V
A
V
V
L
G
E
S
E
V
A
N
G
T
A
V
V
K
D
L
R
S
G
E
--
Q
T
A
V
A
Q
D
S
V
A
A
H
L
R
T
L
L
-------
38
PsiBlast_CBE
81.46
41%
-21
- C2 -
-
1ADJ
1
SYH_THET8
C:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
LG
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
39
PsiBlast_CBE
80.65
41%
-20
- C2 -
-
1ADJ
1
SYH_THET8
B:
[2-412]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
G
V
G
A
A
T
D
I
V
R
K
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
E
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
LG
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
5
PsiBlast_PDB
80.24
43%
15
- C2 -
-
4E51
1
SYH_BURTA
A:
[36-452]
------
K
G
M
N
D
I
L
P
Q
D
A
G
L
W
E
F
F
E
A
T
V
K
S
L
L
R
A
Y
G
Y
Q
N
I
R
T
P
I
V
E
H
T
P
L
F
T
R
G
I
G
E
V
T
D
I
V
E
K
E
M
Y
S
F
V
D
AL
N
-
G
E
---
N
L
T
L
R
P
E
N
T
A
A
V
V
R
A
A
I
E
H
N
M
L
---
Y
D
G
P
K
R
L
W
Y
I
G
P
M
F
R
H
E
R
P
---
R
Y
R
Q
F
H
Q
V
G
V
E
A
L
G
F
A
G
P
D
A
D
A
E
I
V
M
M
C
Q
R
L
W
E
D
L
G
L
T
-
G
-
I
K
L
E
I
N
S
L
G
L
A
E
E
R
A
A
H
R
V
E
L
I
K
Y
L
E
Q
H
A
D
K
L
D
D
D
A
Q
R
R
L
Y
T
N
P
L
R
V
L
D
T
K
N
P
A
L
Q
E
I
V
R
N
--
A
--
P
K
L
I
D
F
L
G
D
V
S
R
A
H
F
E
G
L
Q
R
L
L
K
A
N
N
V
P
F
T
I
N
P
R
L
V
R
G
L
D
Y
Y
N
L
T
V
F
E
W
V
T
D
--
K
------
G
T
V
A
A
G
G
R
Y
D
P
L
I
E
Q
L
G
G
K
---
P
T
A
A
C
G
W
A
M
G
I
E
R
I
L
E
L
L
K
-
E
E
H
L
V
P
E
Q
E
G
---
V
D
V
Y
V
V
H
Q
G
D
A
A
R
E
Q
A
F
I
V
A
E
R
L
R
D
T
------
G
L
D
V
I
L
H
C
S
A
D
G
A
--
G
----
A
S
F
-----
K
S
Q
M
K
R
A
D
A
S
G
A
A
F
A
V
I
F
G
E
D
E
V
T
N
G
T
A
S
V
K
P
L
----S
V
Q
Q
S
V
P
V
E
S
L
T
E
-------------
44
HHSearch
80.03
42%
-32
* C2 *
-
1KMN
2
SYH_ECOLI
C:
[5-423]
--
I
Q
A
I
R
G
M
N
D
Y
L
P
G
E
T
A
I
W
Q
R
I
E
G
T
L
K
N
V
L
G
S
Y
G
Y
S
E
I
R
L
P
I
V
E
Q
T
P
L
F
K
R
A
I
G
E
V
T
D
V
V
E
K
E
M
Y
T
F
E
D
--
R
-
N
G
--
D
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
G
I
E
H
G
L
L
---
Y
N
Q
E
Q
R
L
W
Y
I
G
P
M
F
R
H
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
L
G
C
E
V
F
G
L
Q
G
P
D
I
D
A
E
L
I
M
L
T
A
R
W
W
R
A
L
G
I
S
E
H
-
V
T
L
E
L
N
S
I
G
S
L
E
A
R
A
N
Y
R
D
A
L
V
A
F
L
E
Q
H
--------------------------------------
P
A
L
G
D
Y
L
D
E
E
S
R
E
H
F
A
G
L
C
K
L
L
E
S
A
G
I
A
Y
T
V
N
Q
R
L
V
R
G
L
D
Y
Y
N
R
T
V
F
E
W
V
T
N
S
L
----
G
S
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
E
Q
L
G
G
R
---
A
T
P
A
V
G
F
A
M
G
L
E
R
L
V
L
L
V
Q
A
V
N
P
E
F
K
A
D
P
V
---
V
D
I
Y
L
V
A
S
G
A
D
T
Q
S
A
A
M
A
L
A
E
R
L
R
D
E
------
L
P
G
----
V
K
L
M
T
N
H
G
G
----
G
N
F
-----
K
K
Q
F
A
R
A
D
K
W
G
A
R
V
A
V
V
L
G
E
S
E
V
A
N
G
T
A
V
V
K
D
L
R
S
G
E
--
Q
T
A
V
A
Q
D
S
V
A
A
H
L
R
T
L
L
-------
46
HHSearch
79.98
42%
-5
- C2 -
-
5E3I
2
SYH_ACIBS
B:
[12-437]
--
I
V
A
I
K
G
F
N
D
V
L
P
T
Q
T
A
A
W
R
R
L
E
Q
H
L
A
S
L
M
D
A
Y
G
Y
Q
Q
I
R
L
P
I
V
E
Q
T
G
L
F
K
R
A
I
G
D
A
T
D
I
V
E
K
E
M
Y
T
F
F
D
--
K
-
G
N
P
P
E
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
L
V
E
H
N
L
---
L
R
G
A
T
P
R
V
W
Y
M
G
P
M
F
R
Y
E
K
P
Q
K
G
R
Y
R
Q
F
H
Q
F
G
V
E
T
F
G
V
A
T
P
D
I
D
A
E
L
I
M
L
T
A
R
L
W
K
R
M
G
V
D
H
M
-
V
Q
L
E
L
N
T
L
G
E
T
D
E
R
T
E
Y
R
N
A
L
V
A
F
L
N
E
-----------------------------
K
I
L
E
N
--
A
--
P
K
L
H
D
F
L
K
E
D
S
L
S
H
F
Q
Q
L
Q
D
Y
L
T
A
A
G
I
K
F
V
I
N
Q
K
L
V
R
G
L
D
Y
Y
N
K
T
V
F
E
W
T
T
T
A
L
----
G
S
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
G
Q
L
K
G
K
ADQ
S
V
P
A
V
G
F
A
M
G
M
E
R
L
L
L
L
L
E
Q
V
E
Q
A
E
I
-
V
R
D
---
C
E
A
F
L
V
A
E
-
P
A
Y
Q
S
K
A
L
V
L
A
E
Q
L
R
D
Q
L
E
A
A
NS
N
I
R
----
I
K
T
G
-
S
--
Q
----
G
S
M
-----
K
S
Q
M
K
K
A
D
Q
A
G
A
V
Y
A
I
I
L
G
E
R
E
W
E
A
Q
Q
L
A
V
K
E
L
A
T
A
E
--
Q
S
Q
V
A
L
A
E
L
V
P
F
L
I
E
K
F
T
------
21
PsiBlast_CBE
79.68
41%
-33
- C2 -
-
1HTT
1
SYH_ECOLI
D:
[3-418]
-
N
I
Q
A
I
R
G
M
N
D
Y
L
P
G
E
T
A
I
W
Q
R
I
E
G
T
L
K
N
V
L
G
S
Y
G
Y
S
E
I
R
L
P
I
V
E
Q
T
P
L
F
K
R
A
I
G
E
V
T
D
V
V
E
K
E
M
Y
T
F
E
D
--
R
-
N
G
--
D
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
G
I
E
H
G
L
L
---
Y
N
Q
E
Q
R
L
W
Y
I
G
P
M
F
R
H
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
L
G
C
E
V
F
G
L
Q
G
P
D
I
D
A
E
L
I
M
L
T
A
R
W
W
R
A
L
G
I
S
-
E
H
V
T
L
E
L
N
S
I
G
----------------------------------------------------------------
D
E
E
S
R
E
H
F
A
G
L
C
K
L
L
E
S
A
G
I
A
Y
T
V
N
Q
R
L
V
R
G
L
D
Y
Y
N
R
T
V
F
E
W
V
T
N
--------
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
E
Q
L
G
G
R
---
A
T
P
A
V
G
F
A
M
G
L
E
R
L
V
L
L
V
Q
A
---
V
N
P
E
F
K
A
DPV
V
D
I
Y
L
V
A
S
G
A
D
T
Q
S
A
A
M
A
L
A
E
R
L
R
D
E
LP----
G
V
K
----
L
M
T
N
H
G
--
G
----
G
N
F
-----
K
K
Q
F
A
R
A
D
K
W
G
A
R
V
A
V
V
L
G
E
S
E
V
A
N
G
T
A
V
V
K
D
L
R
S
G
E
--
Q
T
A
V
A
Q
D
S
V
A
A
H
L
-----------
24
PsiBlast_CBE
79.35
41%
-41
- C2 -
-
1KMN
2
SYH_ECOLI
D:
[4-419]
-
N
I
Q
A
I
R
G
M
N
D
Y
L
P
G
E
T
A
I
W
Q
R
I
E
G
T
L
K
N
V
L
G
S
Y
G
Y
S
E
I
R
L
P
I
V
E
Q
T
P
L
F
K
R
A
I
G
E
V
T
D
V
V
E
K
E
M
Y
T
F
E
D
--
R
-
N
G
--
D
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
G
I
E
H
G
L
L
---
Y
N
Q
E
Q
R
L
W
Y
I
G
P
M
F
R
H
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
L
G
C
E
V
F
G
L
Q
G
P
D
I
D
A
E
L
I
M
L
T
A
R
W
W
R
A
L
G
I
S
-
E
H
V
T
L
E
L
N
S
I
G
---------------------------------------------------------------
L
D
E
E
S
R
E
H
F
A
G
L
C
K
L
L
E
S
A
G
I
A
Y
T
V
N
Q
R
L
V
R
G
L
D
Y
Y
N
R
T
V
F
E
W
V
T
N
S
---
L
-
G
S
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
E
Q
L
G
G
R
---
A
T
P
A
V
G
F
A
M
G
L
E
R
L
V
L
L
V
Q
A
---
V
N
P
E
F
K
A
DPV
V
D
I
Y
L
V
A
S
G
A
D
T
Q
S
A
A
M
A
L
A
E
R
L
R
D
E
L
P----
G
V
K
----
L
M
T
N
H
G
--
G
----
G
N
F
-----
K
K
Q
F
A
R
A
D
K
W
G
A
R
V
A
V
V
L
G
E
S
E
V
A
N
G
T
A
V
V
K
D
L
R
S
G
E
--
Q
T
A
V
A
Q
D
S
V
A
A
H
L
-----------
30
PsiBlast_CBE
78.49
43%
0
- C2 -
-
4E51
1
SYH_BURTA
B:
[36-452]
------
K
G
M
N
D
I
L
P
Q
D
A
G
L
W
E
F
F
E
A
T
V
K
S
L
L
R
A
Y
G
Y
Q
N
I
R
T
P
I
V
E
H
T
P
L
F
T
R
------
D
I
V
E
K
E
M
Y
S
F
V
D
AL
N
-
G
E
---
N
L
T
L
R
P
E
N
T
A
A
V
V
R
A
A
I
E
H
N
M
L
---
Y
D
G
P
K
R
L
W
Y
I
G
P
M
F
R
H
E
R
-----
Y
R
Q
F
H
Q
V
G
V
E
A
L
G
F
A
G
P
D
A
D
A
E
I
V
M
M
C
Q
R
L
W
E
D
L
G
L
T
-
G
-
I
K
L
E
I
N
S
L
G
L
A
E
E
R
A
A
H
R
V
E
L
I
K
Y
L
E
Q
H
A
D
------
Q
R
R
L
Y
T
N
P
L
R
V
L
----
P
A
L
Q
E
I
V
R
N
--
A
--
P
K
L
I
D
F
L
G
D
V
S
R
A
H
F
E
G
L
Q
R
L
L
K
A
N
N
V
P
F
T
I
N
P
R
L
V
R
G
L
D
Y
Y
N
L
T
V
F
E
W
V
T
D
---------
G
T
V
A
A
G
G
R
Y
D
P
L
I
E
Q
L
G
G
K
---
P
T
A
A
C
G
W
A
M
G
I
E
R
I
L
E
L
L
K
-
E
E
H
L
V
P
E
Q
E
G
---
V
D
V
Y
V
V
H
Q
G
D
A
A
R
E
Q
A
F
I
V
A
E
R
L
R
D
T
------
G
L
D
V
I
L
H
C
S
A
D
G
A
--
G
----
A
S
F
-----
K
S
Q
M
K
R
A
D
A
S
G
A
A
F
A
V
I
F
G
E
D
E
V
T
N
G
T
A
S
V
K
P
L
----S
V
Q
Q
S
V
P
V
E
S
L
T
E
-------------
10
PsiBlast_PDB
77.75
41%
-16
- C2 -
-
4RDX
2
SYH_THET2
A:
[4-414]
-
T
A
R
A
V
R
G
T
K
D
L
F
G
K
E
L
R
M
H
Q
R
I
V
A
T
A
R
K
V
L
E
A
A
G
A
L
E
L
V
T
P
I
F
E
E
T
Q
V
F
E
K
-----------
E
M
F
T
F
Q
D
--
R
-
G
G
--
R
S
L
T
L
R
P
E
G
T
A
A
M
V
R
A
Y
L
E
H
G
M
--
K
V
W
P
Q
P
V
R
L
W
M
A
G
P
M
F
R
A
E
R
P
Q
K
G
R
Y
R
Q
F
H
Q
V
N
Y
E
A
L
G
S
E
N
P
I
L
D
A
E
A
V
V
L
L
Y
E
C
L
K
E
L
G
L
R
-
R
-
L
K
V
K
L
S
S
V
G
D
P
E
D
R
A
R
Y
N
A
Y
L
R
E
V
L
S
P
H
R
E
A
L
S
E
D
S
K
E
R
L
E
L
N
P
M
R
I
L
D
S
K
S
E
R
D
Q
A
L
L
K
E
L
G
V
--
R
P
M
L
D
F
L
G
E
E
A
R
A
H
L
K
E
V
E
R
H
L
E
R
L
S
V
P
Y
E
L
E
P
A
L
V
R
G
L
D
Y
Y
V
R
T
A
F
E
V
H
H
E
--
E
-
I
-
G
A
Q
S
A
L
G
G
G
G
R
Y
D
G
L
S
E
L
L
G
G
P
---
R
V
P
G
V
G
F
A
F
G
V
E
R
V
A
L
A
L
E
A
E
G
F
G
L
P
E
E
K
G
---
P
D
L
Y
L
I
P
L
T
E
E
A
V
A
E
A
F
Y
L
A
E
A
L
R
P
R
-------
L
R
----
A
E
Y
A
L
A
--
P
----
R
K
P
-----
A
K
G
L
E
E
A
L
K
R
G
A
A
F
A
G
F
L
G
E
D
E
L
R
A
G
E
V
T
L
K
R
L
A
T
G
E
--
Q
V
R
L
S
R
E
E
V
---------------
40
PsiBlast_CBE
75.47
41%
-2
- C2 -
-
5E3I
2
SYH_ACIBS
B:
[16-428]
------
K
G
F
N
D
V
L
P
T
Q
T
A
A
W
R
R
L
E
Q
H
L
A
S
L
M
D
A
Y
G
Y
Q
Q
I
R
L
P
I
V
E
Q
T
G
L
F
K
R
A
I
G
D
A
T
D
I
V
E
K
E
M
Y
T
F
F
D
--
K
-
G
N
P
P
E
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
L
V
E
H
N
L
L
--
R
G
A
T
P
-
R
V
W
Y
M
G
P
M
F
R
Y
E
K
P
Q
K
G
R
Y
R
Q
F
H
Q
F
G
V
E
T
F
G
V
A
T
P
D
I
D
A
E
L
I
M
L
T
A
R
L
W
K
R
M
G
V
D
-
H
M
V
Q
L
E
L
N
T
L
G
E
T
D
E
R
T
E
Y
R
N
A
L
V
A
F
L
N
E
-----------------------------
K
I
L
E
N
--
A
--
P
K
L
H
D
F
L
K
E
D
S
L
S
H
F
Q
Q
L
Q
D
Y
L
T
A
A
G
I
K
F
V
I
N
Q
K
L
V
R
G
L
D
Y
Y
N
K
T
V
F
E
W
T
T
T
A
---
L
-
G
S
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
G
Q
L
K
G
K
ADQ
S
V
P
A
V
G
F
A
M
G
M
E
R
L
L
L
L
L
E
Q
V
E
Q
A
-
E
I
V
R
D
---
C
E
A
F
L
V
A
-
E
P
A
Y
Q
S
K
A
L
V
L
A
E
Q
L
R
D
Q
------
L
E
A
----
A
N
S
N
I
R
--
I
----
K
T
G
S
QGS
M
K
S
Q
M
K
K
A
D
Q
A
G
A
V
Y
A
I
I
L
G
E
R
E
W
E
A
Q
Q
L
A
V
K
E
L
A
T
A
E
--
Q
S
Q
V
A
L
A
E
L
---------------
11
PsiBlast_PDB
73.11
41%
4
- C2 -
-
5E3I
2
SYH_ACIBS
A:
[16-428]
------
K
G
F
N
D
V
L
P
T
Q
T
A
A
W
R
R
L
E
Q
H
L
A
S
L
M
D
A
Y
G
Y
Q
Q
I
R
L
P
I
V
E
Q
T
G
L
F
K
R
A
I
G
D
A
T
D
I
V
E
K
E
M
Y
T
F
F
D
--
K
-
G
N
P
P
E
S
L
T
L
R
P
E
G
T
A
G
C
V
R
A
L
V
E
H
N
L
L
--
R
G
A
T
P
-
R
V
W
Y
M
G
P
M
F
R
Y
E
K
P
Q
K
G
R
Y
R
Q
F
H
Q
F
G
V
E
T
F
G
V
A
T
P
D
I
D
A
E
L
I
M
L
T
A
R
L
W
K
R
M
G
V
D
-
H
M
V
Q
L
E
L
N
T
L
G
E
T
D
E
R
T
E
Y
R
N
A
-------------------------------------------
A
--
P
K
L
H
D
F
L
K
E
D
S
L
S
H
F
Q
Q
L
Q
D
Y
L
T
A
A
G
I
K
F
V
I
N
Q
K
L
V
R
G
L
D
Y
Y
N
K
T
V
F
E
W
T
T
T
A
---
L
-
G
S
Q
G
T
V
C
A
G
G
R
Y
D
G
L
V
G
Q
L
K
G
K
ADQ
S
V
P
A
V
G
F
A
M
G
M
E
R
L
L
L
L
L
E
Q
V
E
Q
A
-
E
I
V
R
D
---
C
E
A
F
L
V
A
-
E
P
A
Y
Q
S
K
A
L
V
L
A
E
Q
L
R
D
Q
------
L
E
A
----
A
N
S
N
I
R
--
I
----
K
T
G
S
QGS
M
K
S
Q
M
K
K
A
D
Q
A
G
A
V
Y
A
I
I
L
G
E
R
E
W
E
A
Q
Q
L
A
V
K
E
L
A
T
A
E
--
Q
S
Q
V
A
L
A
E
L
---------------