@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XY89: (2018-01-08 )
MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVVLEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDLETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTEQGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQEKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAFRSVGRIEDVVEKAKTLGY
Atome Classification :
(21 SA)
.........10........20........30........40..----......50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200....------...210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MSSG
K
I
V
Q
V
IG
P
V
V
D
V
E
F
SLDQSLPDIN
N
A
L
V
V
Y
KNDENK
S
K
V
----
V
L
E
A
A
L
E
LGDG
V
I
R
T
IAMES
T
D
G
L
Q
R
G
M
E
V
IDTG
K
A
I
SVPV
G
K
E
T
L
G
R
V
F
N
VLGDTIDLETPFPEDA
E
R
S
E
I
H
KKAPAFDELS
T
S
T
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
LKGG
K
V
G
L
FGGAGV
G
K
T
V
L
I
Q
E
L
I
H
N
I
A
Q
EHG
G
I
S
V
F
TGVGERTREGN
D
L
Y
Y
EMKDSG
V
I
E
------
K
T
A
M
V
FGQMNEPPG
A
R
M
R
V
A
LTG
L
T
I
A
E
Y
F
R
DVEG
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
QAG
S
E
V
S
A
L
L
GRMPSAVGYQ
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
TSTKKGS
I
T
S
I
Q
A
I
Y
VPADDYTDPAPA
T
A
F
A
HLDATT
N
L
E
R
K
L
T
EQGIYPAVDPLASSSSAL
A
P
E
IVG
E
E
H
Y
K
V
A
T
E
V
Q
H
V
L
Q
R
Y
R
E
L
Q
D
I
I
A
I
LG
M
D
ELS
D
Q
E
K
V
L
V
S
R
A
R
R
V
Q
F
F
L
SQNF
N
V
A
E
Q
FTGLPGSYV
P
V
E
E
T
V
K
G
F
R
E
I
LEGKYDDL
P
E
E
A
F
R
SVG
R
I
E
D
V
V
E
K
A
K
TLGY
3
PsiBlast_PDB
97.05
76%
-79
- C6 -
-
5HKK
2
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
-
L
P
D
I
Y
N
A
I
T
I
E
R
--
P
Q
G
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
-
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
180
HHSearch
96.43
77%
-79
- C6 -
-
5IK2
1
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
-
G
Q
L
P
D
I
Y
N
A
I
T
I
-
E
R
P
Q
G
-
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
-
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
4
PsiBlast_PDB
96.31
76%
-80
- C6 -
-
5IK2
1
?
D:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
-
L
P
D
I
Y
N
A
I
T
I
E
R
--
P
Q
G
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
-
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
29
PsiBlast_CBE
95.00
76%
-76
- C6 -
-
5HKK
1
?
F:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
-
L
P
D
I
Y
N
A
I
T
I
E
R
--
P
Q
G
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
-
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
30
PsiBlast_CBE
94.82
76%
-77
- C6 -
-
5HKK
3
?
E:
[2-462]
-
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
-
L
P
D
I
Y
N
A
I
T
I
E
R
--
P
Q
G
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
-
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
181
HHSearch
94.81
77%
-80
- C6 -
-
5IK2
1
?
F:
[1-462]
M
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
-
G
Q
L
P
D
I
Y
N
A
I
T
I
-
E
R
P
Q
G
-
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
-
E
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
24
PsiBlast_CBE
94.71
76%
-80
- C6 -
-
5IK2
1
?
F:
[1-462]
M
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
-
L
P
D
I
Y
N
A
I
T
I
E
R
--
P
Q
G
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
-
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
25
PsiBlast_CBE
94.52
76%
-75
- C6 -
-
5IK2
1
?
E:
[1-462]
M
N
K
G
R
I
I
Q
V
M
G
P
V
V
D
I
Q
F
E
S
G
Q
-
L
P
D
I
Y
N
A
I
T
I
E
R
--
P
Q
G
G
T
L
----
T
V
E
A
A
V
H
L
G
D
N
V
V
R
C
V
A
M
A
S
T
D
G
L
V
R
G
L
E
A
V
D
T
G
A
P
I
S
V
P
V
G
K
A
T
L
G
R
V
F
N
V
L
G
E
P
I
D
E
Q
G
E
V
N
A
E
-
E
R
H
P
I
H
R
P
A
P
E
F
E
E
L
S
T
A
D
E
I
L
E
T
G
I
K
V
I
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
N
N
V
A
Q
E
H
G
G
L
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
S
M
V
F
G
Q
M
N
E
P
P
G
A
R
L
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
R
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
A
S
T
S
R
I
L
S
P
A
V
V
G
E
E
H
Y
R
V
A
R
G
V
Q
Q
V
L
Q
R
Y
N
D
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
I
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
Q
F
T
G
M
P
G
K
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
H
D
N
L
P
E
E
A
F
Y
M
V
G
T
I
D
E
A
V
E
K
A
K
K
L
--
14
PsiBlast_PDB
86.99
65%
-88
- C6 -
-
4Q4L
-
ATPB1_BURTA
A:
[30-484]
---
G
K
I
V
Q
C
I
G
A
V
I
D
V
E
F
P
-
R
E
S
M
P
K
I
Y
D
A
L
I
L
-----
E
G
S
E
L
----
T
L
E
V
Q
Q
Q
L
G
D
G
V
V
R
T
I
C
L
G
A
---
L
R
R
G
V
V
V
K
N
T
G
N
P
I
S
V
P
V
G
K
P
T
L
G
R
I
M
D
V
L
G
R
P
I
D
E
A
G
P
I
E
S
E
N
K
R
S
-
I
H
Q
K
A
P
A
F
D
E
L
S
P
S
T
E
L
L
E
T
G
I
K
V
I
D
L
I
C
P
F
A
K
G
G
K
V
G
L
F
G
G
A
G
V
G
K
T
V
N
M
M
E
L
I
N
N
I
A
K
E
H
G
G
Y
S
V
F
A
G
V
-------
N
D
F
Y
H
E
M
K
D
S
N
V
L
D
------
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
N
R
L
R
V
A
L
T
G
L
T
M
A
E
H
F
R
D
-
E
G
L
D
V
L
F
F
V
D
N
I
Y
R
F
T
L
A
G
T
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
E
E
M
G
K
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
V
Q
A
V
Y
V
P
A
-------------
H
L
D
A
T
V
V
L
S
R
D
I
A
S
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
Q
I
D
P
N
V
I
G
E
E
H
Y
S
I
T
R
R
V
Q
Q
T
L
Q
R
Y
K
E
L
R
D
I
I
A
I
L
G
M
D
E
L
S
P
E
D
K
L
S
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
V
F
T
G
S
P
G
K
Y
V
P
L
K
E
T
I
R
G
F
K
M
I
V
D
G
E
C
D
H
L
P
E
Q
A
F
Y
M
V
G
T
I
D
E
A
F
E
K
A
K
K
I
--
182
HHSearch
86.86
66%
-86
- C6 -
-
4Q4L
-
ATPB1_BURTA
A:
[28-484]
-
V
E
G
K
I
V
Q
C
I
G
A
V
I
D
V
E
F
P
R
-
E
S
M
P
K
I
Y
D
A
L
I
L
-
E
G
----
S
E
L
----
T
L
E
V
Q
Q
Q
L
G
D
G
V
V
R
T
I
C
L
G
A
---
L
R
R
G
V
V
V
K
N
T
G
N
P
I
S
V
P
V
G
K
P
T
L
G
R
I
M
D
V
L
G
R
P
I
D
E
A
G
P
I
E
S
-
E
N
K
R
S
I
H
Q
K
A
P
A
F
D
E
L
S
P
S
T
E
L
L
E
T
G
I
K
V
I
D
L
I
C
P
F
A
K
G
G
K
V
G
L
F
G
G
A
G
V
G
K
T
V
N
M
M
E
L
I
N
N
I
A
K
E
H
G
G
Y
S
V
F
A
G
V
-------
N
D
F
Y
H
E
M
K
D
S
N
V
L
D
------
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
N
R
L
R
V
A
L
T
G
L
T
M
A
E
H
F
R
D
-
E
G
L
D
V
L
F
F
V
D
N
I
Y
R
F
T
L
A
G
T
E
V
S
A
L
L
G
R
M
P
S
A
V
G
Y
Q
P
T
L
A
E
E
M
G
K
L
Q
E
R
I
T
S
T
K
K
G
S
I
T
S
V
Q
A
V
Y
V
P
A
-------------
H
L
D
A
T
V
V
L
S
R
D
I
A
S
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
Q
I
D
P
N
V
I
G
E
E
H
Y
S
I
T
R
R
V
Q
Q
T
L
Q
R
Y
K
E
L
R
D
I
I
A
I
L
G
M
D
E
L
S
P
E
D
K
L
S
V
A
R
A
R
K
I
Q
R
F
L
S
Q
P
F
H
V
A
E
V
F
T
G
S
P
G
K
Y
V
P
L
K
E
T
I
R
G
F
K
M
I
V
D
G
E
C
D
H
L
P
E
Q
A
F
Y
M
V
G
T
I
D
E
A
F
E
K
A
K
K
I
--
5
PsiBlast_PDB
86.14
67%
0
- C- -
-
4B2Q
-
ATPB_YEAST
D:
[5-468]
--
T
G
K
V
T
A
V
I
G
A
I
V
D
V
H
F
E
Q
S
E
-
L
P
A
I
L
N
A
L
E
I
---
K
T
P
Q
G
K
L
----
V
L
E
V
A
Q
H
L
G
E
N
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
E
K
V
L
D
T
G
G
P
I
S
V
P
V
G
R
E
T
L
G
R
I
I
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
S
K
L
R
K
P
I
H
A
D
P
P
S
F
A
E
Q
S
T
S
A
E
I
L
E
T
G
I
K
V
V
D
L
L
A
P
Y
A
R
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
F
I
Q
E
L
I
N
N
I
A
K
A
H
G
G
F
S
V
F
T
G
V
G
E
R
T
R
E
G
N
D
L
Y
R
E
M
K
E
T
G
V
I
N
LEGES-
K
V
A
L
V
F
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
I
A
E
Y
F
R
D
E
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
L
L
Q
E
R
I
T
T
T
K
K
G
S
V
T
S
V
Q
A
V
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
G
I
S
E
L
G
I
Y
P
A
V
D
P
L
D
S
K
S
R
L
L
D
A
A
V
V
G
Q
E
H
Y
D
V
A
S
K
V
Q
E
T
L
Q
T
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
Q
D
K
L
T
V
E
R
A
R
K
I
Q
R
F
L
S
Q
P
F
A
V
A
E
V
F
T
G
I
P
G
K
L
V
R
L
K
D
T
V
A
S
F
K
A
V
L
E
G
K
Y
D
N
I
P
E
H
A
F
Y
M
V
G
G
I
E
D
V
V
A
K
A
E
K
L
--
12
PsiBlast_PDB
85.55
68%
0
- C- -
-
3OEE
-
ATPB_YEAST
D:
[16-473]
--
T
G
K
V
T
A
V
I
G
A
I
V
D
V
H
F
E
Q
S
E
-
L
P
A
I
L
N
A
L
E
I
---
K
T
P
Q
G
K
L
----
V
L
E
V
A
Q
H
L
G
E
N
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
E
K
V
L
D
T
G
G
P
I
S
V
P
V
G
R
E
T
L
G
R
I
I
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
S
K
L
R
K
P
I
H
A
D
P
P
S
F
A
E
Q
S
T
S
A
E
I
L
E
T
G
I
K
V
V
D
L
L
A
P
Y
A
R
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
F
I
Q
E
L
I
N
N
I
A
K
A
H
G
G
F
S
V
F
T
G
V
G
E
R
T
R
E
G
N
D
L
Y
R
E
M
K
E
T
G
V
I
N
LEGES-
K
V
A
L
V
F
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
I
A
E
Y
F
R
D
E
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
L
L
Q
E
R
I
T
T
T
K
K
G
S
V
T
S
V
Q
A
V
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
G
I
S
E
L
G
I
Y
P
A
V
D
P
L
D
S
K
S
R
L
L
D
A
A
V
V
G
Q
E
H
Y
D
V
A
S
K
V
Q
E
T
L
Q
T
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
Q
D
K
L
T
V
E
R
A
R
K
I
Q
R
F
L
S
Q
P
F
A
V
A
E
V
F
T
G
I
P
G
K
L
V
R
L
K
D
T
V
A
S
F
K
A
V
L
E
G
K
Y
D
N
I
P
E
H
A
F
Y
M
V
G
G
I
E
D
V
V
--------
11
PsiBlast_PDB
85.55
68%
0
- C- -
-
3OE7
-
ATPB_YEAST
D:
[16-473]
--
T
G
K
V
T
A
V
I
G
A
I
V
D
V
H
F
E
Q
S
E
-
L
P
A
I
L
N
A
L
E
I
---
K
T
P
Q
G
K
L
----
V
L
E
V
A
Q
H
L
G
E
N
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
E
K
V
L
D
T
G
G
P
I
S
V
P
V
G
R
E
T
L
G
R
I
I
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
S
K
L
R
K
P
I
H
A
D
P
P
S
F
A
E
Q
S
T
S
A
E
I
L
E
T
G
I
K
V
V
D
L
L
A
P
Y
A
R
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
F
I
Q
E
L
I
N
N
I
A
K
A
H
G
G
F
S
V
F
T
G
V
G
E
R
T
R
E
G
N
D
L
Y
R
E
M
K
E
T
G
V
I
N
LEGES-
K
V
A
L
V
F
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
I
A
E
Y
F
R
D
E
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
L
L
Q
E
R
I
T
T
T
K
K
G
S
V
T
S
V
Q
A
V
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
G
I
S
E
L
G
I
Y
P
A
V
D
P
L
D
S
K
S
R
L
L
D
A
A
V
V
G
Q
E
H
Y
D
V
A
S
K
V
Q
E
T
L
Q
T
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
Q
D
K
L
T
V
E
R
A
R
K
I
Q
R
F
L
S
Q
P
F
A
V
A
E
V
F
T
G
I
P
G
K
L
V
R
L
K
D
T
V
A
S
F
K
A
V
L
E
G
K
Y
D
N
I
P
E
H
A
F
Y
M
V
G
G
I
E
D
V
V
--------
7
PsiBlast_PDB
85.55
68%
0
- C- -
-
2HLD
-
ATPB_YEAST
D:
[10-467]
--
T
G
K
V
T
A
V
I
G
A
I
V
D
V
H
F
E
Q
S
E
-
L
P
A
I
L
N
A
L
E
I
---
K
T
P
Q
G
K
L
----
V
L
E
V
A
Q
H
L
G
E
N
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
E
K
V
L
D
T
G
G
P
I
S
V
P
V
G
R
E
T
L
G
R
I
I
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
S
K
L
R
K
P
I
H
A
D
P
P
S
F
A
E
Q
S
T
S
A
E
I
L
E
T
G
I
K
V
V
D
L
L
A
P
Y
A
R
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
F
I
Q
E
L
I
N
N
I
A
K
A
H
G
G
F
S
V
F
T
G
V
G
E
R
T
R
E
G
N
D
L
Y
R
E
M
K
E
T
G
V
I
N
LEGES-
K
V
A
L
V
F
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
I
A
E
Y
F
R
D
E
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
L
L
Q
E
R
I
T
T
T
K
K
G
S
V
T
S
V
Q
A
V
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
G
I
S
E
L
G
I
Y
P
A
V
D
P
L
D
S
K
S
R
L
L
D
A
A
V
V
G
Q
E
H
Y
D
V
A
S
K
V
Q
E
T
L
Q
T
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
Q
D
K
L
T
V
E
R
A
R
K
I
Q
R
F
L
S
Q
P
F
A
V
A
E
V
F
T
G
I
P
G
K
L
V
R
L
K
D
T
V
A
S
F
K
A
V
L
E
G
K
Y
D
N
I
P
E
H
A
F
Y
M
V
G
G
I
E
D
V
V
--------
1
PsiBlast_PDB
84.08
78%
2
- C6 -
-
1SKY
-
ATPB_BACP3
E:
[1-470]
M
T
R
G
R
V
I
Q
V
M
G
P
V
V
D
V
K
F
E
-
N
G
H
L
P
A
I
Y
N
A
L
K
I
Q
H
K
A
R
N
E
N
E
V
DIDL
T
L
E
V
A
L
H
L
G
D
D
T
V
R
T
I
A
M
A
S
T
D
G
L
I
R
G
M
E
V
I
D
T
G
A
P
I
S
V
P
V
G
Q
V
T
L
G
R
V
F
N
V
L
G
E
P
I
D
L
E
G
D
I
P
A
D
A
R
R
D
P
I
H
R
P
A
P
K
F
E
E
L
A
T
E
V
E
I
L
E
T
G
I
K
V
V
D
L
L
A
P
Y
I
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
Q
E
L
I
H
N
I
A
Q
E
H
G
G
I
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
K
D
S
G
V
I
S
------
K
T
A
M
V
F
G
Q
M
N
E
P
P
G
A
R
M
R
V
A
L
T
G
L
T
M
A
E
Y
F
R
D
E
Q
G
Q
D
G
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
M
P
S
A
I
G
Y
Q
P
T
L
A
T
E
M
G
Q
L
Q
E
R
I
T
S
T
A
K
G
S
I
T
S
I
Q
A
I
Y
V
P
A
D
D
Y
T
D
P
A
P
A
T
T
F
S
H
L
D
A
T
T
N
L
E
R
K
L
A
E
M
G
I
Y
P
A
V
D
P
L
V
S
T
S
R
A
L
A
P
E
I
V
G
E
E
H
Y
Q
V
A
R
K
V
Q
Q
T
L
E
R
Y
K
E
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
D
E
D
K
L
V
V
H
R
A
R
R
I
Q
F
F
L
S
Q
N
F
H
V
A
E
Q
F
T
G
Q
P
G
S
Y
V
P
V
K
E
T
V
R
G
F
K
E
I
L
E
G
K
Y
D
H
L
P
E
D
R
F
R
L
V
G
R
I
E
E
V
V
E
K
A
K
A
M
G
-
131
PsiBlast_CBE
83.80
66%
-16
- C6 -
-
1EFR
1
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
--
D
E
G
L
P
P
I
L
N
A
L
E
V
Q
G
R
E
---
T
R
L
----
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
--
116
PsiBlast_CBE
83.70
66%
-19
- C6 -
-
1W0K
3
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
--
D
E
G
L
P
P
I
L
N
A
L
E
V
Q
G
R
E
---
T
R
L
----
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
--
149
PsiBlast_CBE
83.66
66%
-15
- C6 -
-
4TSF
2
ATPB_BOVIN
F:
[11-475]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
--
D
E
G
L
P
P
I
L
N
A
L
E
V
Q
G
R
E
---
T
R
L
----
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
--
110
PsiBlast_CBE
83.54
66%
-15
- C6 -
-
2JDI
2
ATPB_BOVIN
D:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
--
D
E
G
L
P
P
I
L
N
A
L
E
V
Q
G
R
E
---
T
R
L
----
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
--
87
PsiBlast_CBE
83.53
66%
-17
- C6 -
-
2V7Q
2
ATPB_BOVIN
F:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
--
D
E
G
L
P
P
I
L
N
A
L
E
V
Q
G
R
E
---
T
R
L
----
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
--
102
PsiBlast_CBE
82.33
66%
-15
- C6 -
-
2JIZ
24
ATPB_BOVIN
M:
[13-477]
-
T
T
G
R
I
V
A
V
I
G
A
V
V
D
V
Q
F
--
D
E
G
L
P
P
I
L
N
A
L
E
V
Q
G
R
E
---
T
R
L
----
V
L
E
V
A
Q
H
L
G
E
S
T
V
R
T
I
A
M
D
G
T
E
G
L
V
R
G
Q
K
V
L
D
S
G
A
P
I
R
I
P
V
G
P
E
T
L
G
R
I
M
N
V
I
G
E
P
I
D
E
R
G
P
I
-
K
T
K
Q
F
A
A
I
H
A
E
A
P
E
F
V
E
M
S
V
E
Q
E
I
L
V
T
G
I
K
V
V
D
L
L
A
P
Y
A
K
G
G
K
I
G
L
F
G
G
A
G
V
G
K
T
V
L
I
M
E
L
I
N
N
V
A
K
A
H
G
G
Y
S
V
F
A
G
V
G
E
R
T
R
E
G
N
D
L
Y
H
E
M
I
E
S
G
V
I
N
LKDATS
K
V
A
L
V
Y
G
Q
M
N
E
P
P
G
A
R
A
R
V
A
L
T
G
L
T
V
A
E
Y
F
R
D
Q
E
G
Q
D
V
L
L
F
I
D
N
I
F
R
F
T
Q
A
G
S
E
V
S
A
L
L
G
R
I
P
S
A
V
G
Y
Q
P
T
L
A
T
D
M
G
T
M
Q
E
R
I
T
T
T
K
K
G
S
I
T
S
V
Q
A
I
Y
V
P
A
D
D
L
T
D
P
A
P
A
T
T
F
A
H
L
D
A
T
T
V
L
S
R
A
I
A
E
L
G
I
Y
P
A
V
D
P
L
D
S
T
S
R
I
M
D
P
N
I
V
G
S
E
H
Y
D
V
A
R
G
V
Q
K
I
L
Q
D
Y
K
S
L
Q
D
I
I
A
I
L
G
M
D
E
L
S
E
E
D
K
L
T
V
S
R
A
R
K
I
Q
R
F
L
S
Q
P
F
Q
V
A
E
V
F
T
G
H
L
G
K
L
V
P
L
K
E
T
I
K
G
F
Q
Q
I
L
A
G
E
Y
D
H
L
P
E
Q
A
F
Y
M
V
G
P
I
E
E
A
V
A
K
A
D
K
L
--