@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XYW0: (2018-01-11 )
MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGSGKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEETVAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVLAMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYVLEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELADAIVHYAGGNAHDE
Atome Classification :
(34 SA)
.........10........20........30........40........50........60......--------..70.......-.-80....-....90.----.......100.-........110........120.......130...-....140.......150.......160.......170.......180......--.190.......200.......210.......220.......230..---------.....240.......250.......260..----.....270.......280.......----------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MD
I
R
F
E
Q
V
D
F
T
YQPNTPFE
Q
R
A
L
F
D
I
N
M
T
I
KEN
S
Y
T
A
L
VGHTGS
G
K
S
T
L
L
Q
H
L
N
A
LVKPTS
G
T
V
H
IG--------ERDIQPDTDNK-
N
-
L
K
P
I
R
K
-KV
G
I
V
F
Q----F
P
E
A
Q
L
F
E
--
E
-
T
V
A
K
D
IAFGP-KNFGV
S
E
E
E
A
L
V
L
A
K
E
T
L
E
Q
VGL
D
-
E
S
Y
L
ERSPFELSGG
Q
M
R
R
V
A
I
A
G
V
LAMR
P
E
V
L
V
L
DEPTAGLD
P
Q
G
R
K
E
M
M
E
M
F
--
W
R
LHKEQ
Q
I
T
I
V
L
V
T
H
L
M
D
D
V
A
N
F
A
D
Y
V
Y
V
L
EK
G
R
IVNSG
E
P
Q
E
V
F
---------
Q
N
I
E
W
L
K
E
KQLGVP
T
A
T
E
F
A
E
E
L
M
AKGM
N
F
----ATLPL
T
A
E
E
L
A
D
A
I
V
HYAGGNAHDE----------------------------------------------
145
HHSearch
83.47
61%
-
- C1 -
-
4HZU
-
ECFA2_LACBA
B:
[2-285]
-
A
I
A
F
E
H
V
T
Y
T
Y
Q
A
G
T
P
M
A
H
T
A
L
T
D
V
S
L
T
V
P
D
R
G
Y
L
A
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
A
L
L
K
P
T
S
G
T
I
K
I
D
--------
E
F
T
I
T
P
E
T
T
N
A
-
A
-
L
K
P
L
R
Q
-
H
V
G
M
V
F
Q
----
F
P
E
N
Q
L
F
E
--
E
-
T
V
R
Q
D
I
A
F
G
P
-
K
N
F
G
M
A
D
A
D
A
L
A
L
A
D
E
M
L
T
T
V
G
L
D
-
Q
S
Y
A
E
R
S
P
F
E
L
S
G
G
Q
M
R
R
V
A
I
A
G
V
L
A
M
Q
P
K
V
L
V
L
D
E
P
T
A
G
L
D
P
Q
G
R
Q
E
M
M
R
L
F
--
A
R
L
H
Q
E
Q
G
L
T
I
V
L
V
T
H
Q
M
E
D
V
A
Q
Y
A
E
Q
V
A
V
M
H
E
G
R
L
M
K
F
G
T
P
A
D
V
F
---------
S
N
R
E
W
L
Q
D
H
Q
L
D
V
P
Q
A
A
Q
F
A
R
R
L
R
D
R
G
L
T
F
----
P
K
Q
P
L
T
A
D
Q
L
A
D
Y
L
A
Q
Q
W
A
Q
R
--------------------------------------------------
146
HHSearch
83.29
61%
-
- C1 -
-
4HUQ
-
ECFA2_LACBA
A:
[2-285]
-
A
I
A
F
E
H
V
T
Y
T
Y
Q
A
G
T
P
M
A
H
T
A
L
T
D
V
S
L
T
V
P
D
R
G
Y
L
A
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
A
L
L
K
P
T
S
G
T
I
K
I
D
--------
E
F
T
I
T
P
E
T
T
N
A
-
A
-
L
K
P
L
R
Q
-
H
V
G
M
V
F
Q
----
F
P
E
N
Q
L
F
E
--
E
-
T
V
R
Q
D
I
A
F
G
P
-
K
N
F
G
M
A
D
A
D
A
L
A
L
A
D
E
M
L
T
T
V
G
L
D
-
Q
S
Y
A
E
R
S
P
F
E
L
S
G
G
Q
M
R
R
V
A
I
A
G
V
L
A
M
Q
P
K
V
L
V
L
D
E
P
T
A
G
L
D
P
Q
G
R
Q
E
M
M
R
L
F
--
A
R
L
H
Q
E
Q
G
L
T
I
V
L
V
T
H
Q
M
E
D
V
A
Q
Y
A
E
Q
V
A
V
M
H
E
G
R
L
M
K
F
G
T
P
A
D
V
F
---------
S
N
R
E
W
L
Q
D
H
Q
L
D
V
P
Q
A
A
Q
F
A
R
R
L
R
D
R
G
L
T
F
----
P
K
Q
P
L
T
A
D
Q
L
A
D
Y
L
A
Q
Q
W
A
Q
R
--------------------------------------------------
2
PsiBlast_PDB
81.16
62%
-
- C1 -
-
4HZU
-
ECFA2_LACBA
B:
[2-278]
-
A
I
A
F
E
H
V
T
Y
T
Y
Q
A
G
T
P
M
A
H
T
A
L
T
D
V
S
L
T
V
P
D
R
G
Y
L
A
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
A
L
L
K
P
T
S
G
T
I
K
I
D
--------
E
F
T
I
T
P
E
T
T
N
A
-
A
-
L
K
P
L
R
Q
-
H
V
G
M
V
F
Q
----
F
P
E
N
Q
L
F
E
--
E
-
T
V
R
Q
D
I
A
F
G
P
-
K
N
F
G
M
A
D
A
D
A
L
A
L
A
D
E
M
L
T
T
V
G
L
D
-
Q
S
Y
A
E
R
S
P
F
E
L
S
G
G
Q
M
R
R
V
A
I
A
G
V
L
A
M
Q
P
K
V
L
V
L
D
E
P
T
A
G
L
D
P
Q
G
R
Q
E
M
M
R
L
F
--
A
R
L
H
Q
E
Q
G
L
T
I
V
L
V
T
H
Q
M
E
D
V
A
Q
Y
A
E
Q
V
A
V
M
H
E
G
R
L
M
K
F
G
T
P
A
D
V
F
---------
S
N
R
E
W
L
Q
D
H
Q
L
D
V
P
Q
A
A
Q
F
A
R
R
L
R
D
R
G
L
T
F
----
P
K
Q
P
L
T
A
D
Q
L
A
D
Y
L
---------------------------------------------------------
1
PsiBlast_PDB
80.97
62%
-
- C1 -
-
4HUQ
-
ECFA2_LACBA
A:
[2-278]
-
A
I
A
F
E
H
V
T
Y
T
Y
Q
A
G
T
P
M
A
H
T
A
L
T
D
V
S
L
T
V
P
D
R
G
Y
L
A
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
A
L
L
K
P
T
S
G
T
I
K
I
D
--------
E
F
T
I
T
P
E
T
T
N
A
-
A
-
L
K
P
L
R
Q
-
H
V
G
M
V
F
Q
----
F
P
E
N
Q
L
F
E
--
E
-
T
V
R
Q
D
I
A
F
G
P
-
K
N
F
G
M
A
D
A
D
A
L
A
L
A
D
E
M
L
T
T
V
G
L
D
-
Q
S
Y
A
E
R
S
P
F
E
L
S
G
G
Q
M
R
R
V
A
I
A
G
V
L
A
M
Q
P
K
V
L
V
L
D
E
P
T
A
G
L
D
P
Q
G
R
Q
E
M
M
R
L
F
--
A
R
L
H
Q
E
Q
G
L
T
I
V
L
V
T
H
Q
M
E
D
V
A
Q
Y
A
E
Q
V
A
V
M
H
E
G
R
L
M
K
F
G
T
P
A
D
V
F
---------
S
N
R
E
W
L
Q
D
H
Q
L
D
V
P
Q
A
A
Q
F
A
R
R
L
R
D
R
G
L
T
F
----
P
K
Q
P
L
T
A
D
Q
L
A
D
Y
L
---------------------------------------------------------
3
PsiBlast_PDB
80.93
62%
-
- C1 -
-
4RFS
-
ECFA2_LACBA
A:
[2-278]
-
A
I
A
F
E
H
V
T
Y
T
Y
Q
A
G
T
P
M
A
H
T
A
L
T
D
V
S
L
T
V
P
D
R
G
Y
L
A
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
A
L
L
K
P
T
S
G
T
I
K
I
D
--------
E
F
T
I
T
P
E
T
T
N
A
-
A
-
L
K
P
L
R
Q
-
H
V
G
M
V
F
Q
----
F
P
E
N
Q
L
F
E
--
E
-
T
V
R
Q
D
I
A
F
G
P
-
K
N
F
G
M
A
D
A
D
A
L
A
L
A
D
E
M
L
T
T
V
G
L
D
-
Q
S
Y
A
E
R
S
P
F
E
L
S
G
G
Q
M
R
R
V
A
I
A
G
V
L
A
M
Q
P
K
V
L
V
L
D
E
P
T
A
G
L
D
P
Q
G
R
Q
E
M
M
R
L
F
--
A
R
L
H
Q
E
Q
G
L
T
I
V
L
V
T
H
Q
M
E
D
V
A
Q
Y
A
E
Q
V
A
V
M
H
E
G
R
L
M
K
F
G
T
P
A
D
V
F
---------
S
N
R
E
W
L
Q
D
H
Q
L
D
V
P
Q
A
A
Q
F
A
R
R
L
R
D
R
G
L
T
F
----
P
K
Q
P
L
T
A
D
Q
L
A
D
Y
L
---------------------------------------------------------
5
PsiBlast_PDB
80.71
52%
-98
- C1 -
-
5JSZ
-
ECFA2_LACDA
B:
[1-282]
M
A
I
K
F
E
N
V
S
Y
V
Y
S
P
G
S
P
L
E
A
I
G
L
D
Q
L
N
F
S
L
E
E
G
K
F
I
A
L
V
G
H
T
G
S
G
K
S
T
L
M
Q
H
F
N
A
L
L
K
P
T
S
G
K
I
E
I
A
--------
G
Y
T
I
T
P
E
T
G
N
K
-
G
-
L
K
D
L
R
R
-
K
V
S
L
A
F
Q
----
F
S
E
A
Q
L
F
E
--
N
-
T
V
L
K
D
V
E
Y
G
P
-
R
N
F
G
F
S
E
D
E
A
R
E
A
A
L
K
W
L
K
K
V
G
L
K
-
D
D
L
I
E
H
S
P
F
D
L
S
G
G
Q
M
R
R
V
A
L
A
G
V
L
A
Y
E
P
E
I
I
C
L
D
E
P
A
A
G
L
D
P
M
G
R
L
E
M
M
Q
L
F
---
K
D
Y
Q
A
A
G
H
T
V
I
L
V
T
H
N
M
D
D
V
A
D
Y
A
D
D
V
L
A
L
E
H
G
R
L
I
K
H
A
S
P
K
E
V
F
---------
K
D
S
E
W
L
Q
K
H
H
L
A
E
P
R
S
A
R
F
A
A
K
L
E
A
A
G
L
K
L
----
P
G
Q
P
L
T
M
P
E
L
A
D
A
I
K
Q
S
L
K
----------------------------------------------------
4
PsiBlast_PDB
78.09
52%
-105
- C1 -
-
5D3M
1
ECFA2_LACDA
B:
[2-282]
-
A
I
K
F
E
N
V
S
Y
V
Y
S
P
G
S
P
L
E
A
I
G
L
D
Q
L
N
F
S
L
E
E
G
K
F
I
A
L
V
G
H
T
G
S
G
K
S
T
L
M
Q
H
F
N
A
L
L
K
P
T
S
G
K
I
E
I
A
--------
G
Y
T
I
T
P
E
T
G
N
K
-
G
-
L
K
D
L
R
R
-
K
V
S
L
A
F
Q
----
F
S
E
A
Q
L
F
E
--
N
-
T
V
L
K
D
V
E
Y
G
P
-
R
N
F
G
F
S
E
D
E
A
R
E
A
A
L
K
W
L
K
K
V
G
L
K
-
D
D
L
I
E
H
S
P
F
D
L
S
G
G
Q
M
R
R
V
A
L
A
G
V
L
A
Y
E
P
E
I
I
C
L
D
E
P
A
A
G
L
D
P
M
G
R
L
E
M
M
Q
L
F
---
K
D
Y
Q
A
A
G
H
T
V
I
L
V
T
H
N
M
D
D
V
A
D
Y
A
D
D
V
L
A
L
E
H
G
R
L
I
K
H
A
S
P
K
E
V
F
---------
K
D
S
E
W
L
Q
K
H
H
L
A
E
P
R
S
A
R
F
A
A
K
L
E
A
A
G
L
K
L
----
P
G
Q
P
L
T
M
P
E
L
A
D
A
I
K
Q
S
L
K
----------------------------------------------------
21
PsiBlast_CBE
77.95
52%
-102
- C1 -
-
5D3M
2
ECFA2_LACDA
F:
[2-282]
-
A
I
K
F
E
N
V
S
Y
V
Y
S
P
G
S
P
L
E
A
I
G
L
D
Q
L
N
F
S
L
E
E
G
K
F
I
A
L
V
G
H
T
G
S
G
K
S
T
L
M
Q
H
F
N
A
L
L
K
P
T
S
G
K
I
E
I
A
--------
G
Y
T
I
T
P
E
T
G
N
K
-
G
-
L
K
D
L
R
R
-
K
V
S
L
A
F
Q
----
F
S
E
A
Q
L
F
E
--
N
-
T
V
L
K
D
V
E
Y
G
P
-
R
N
F
G
F
S
E
D
E
A
R
E
A
A
L
K
W
L
K
K
V
G
L
K
-
D
D
L
I
E
H
S
P
F
D
L
S
G
G
Q
M
R
R
V
A
L
A
G
V
L
A
Y
E
P
E
I
I
C
L
D
E
P
A
A
G
L
D
P
M
G
R
L
E
M
M
Q
L
F
---
K
D
Y
Q
A
A
G
H
T
V
I
L
V
T
H
N
M
D
D
V
A
D
Y
A
D
D
V
L
A
L
E
H
G
R
L
I
K
H
A
S
P
K
E
V
F
---------
K
D
S
E
W
L
Q
K
H
H
L
A
E
P
R
S
A
R
F
A
A
K
L
E
A
A
G
L
K
L
----
P
G
Q
P
L
T
M
P
E
L
A
D
A
I
K
Q
S
L
K
----------------------------------------------------
150
HHSearch
76.83
49%
-111
- C1 -
-
4MKI
2
ECFA2_CALS4
A:
[5-285]
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
--------
G
I
D
I
T
D
K
--
K
V
-
S
-
L
K
D
I
R
K
-
Q
V
G
L
V
F
Q
----
Y
P
E
Y
Q
L
F
E
--
E
-
T
V
F
K
D
I
A
F
G
P
-
S
N
L
G
L
S
E
E
E
V
K
E
R
V
Y
E
A
M
E
I
V
G
I
S
-
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
--
K
E
I
H
D
K
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
---------
R
E
A
E
R
L
E
K
I
G
L
S
V
P
Q
I
T
S
L
A
R
E
L
R
K
R
G
V
P
I
----
P
P
D
V
L
T
I
E
E
A
K
E
H
I
L
R
Y
L
R
----------------------------------------------------
6
PsiBlast_PDB
69.80
48%
-28
- C1 -
-
4MKI
2
ECFA2_CALS4
B:
[5-287]
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
--------
G
I
D
I
---
T
D
K
K
V
S
-
L
K
D
I
R
K
-
Q
V
G
L
V
F
Q
----
Y
P
E
Y
Q
L
F
E
--
E
-
T
V
F
K
D
I
A
F
G
P
-
S
N
L
G
L
S
E
E
E
V
K
E
R
V
Y
E
A
M
E
I
V
G
I
S
-
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
--
K
E
I
H
D
K
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
---------
R
E
A
E
R
L
E
K
I
G
L
S
V
P
Q
I
T
S
L
A
R
E
L
R
K
R
G
V
P
I
----
P
P
D
V
L
T
I
E
E
A
K
E
H
I
L
R
Y
L
R
G
T
--------------------------------------------------
22
PsiBlast_CBE
68.28
48%
-26
- C1 -
-
4MKI
2
ECFA2_CALS4
A:
[5-287]
M
P
I
K
V
E
N
V
S
F
I
Y
N
E
G
T
P
Y
A
T
V
A
L
K
D
I
N
F
S
I
D
D
E
E
F
V
G
I
I
G
H
T
G
S
G
K
S
T
L
I
Q
Q
L
N
G
L
L
K
P
S
K
G
K
I
Y
I
N
--------
G
I
D
I
---
T
D
K
K
V
S
-
L
K
D
I
R
K
-
Q
V
G
L
V
F
Q
----
Y
P
E
Y
Q
L
F
E
--
E
-
T
V
F
K
D
I
A
F
G
P
-
S
N
L
G
L
S
E
E
E
V
K
E
R
V
Y
E
A
M
E
I
V
G
I
S
-
K
E
L
A
D
K
S
P
F
E
L
S
G
G
Q
K
R
R
V
A
I
A
G
I
L
A
M
R
P
K
I
L
I
L
D
E
P
T
A
G
L
D
P
K
G
K
Q
E
I
L
N
K
I
--
K
E
I
H
D
K
Y
K
M
I
T
I
L
V
S
H
N
M
E
D
I
A
R
I
A
D
K
I
I
V
M
N
R
G
K
I
E
L
I
G
T
P
R
E
V
F
---------
R
E
A
E
R
L
E
K
I
G
L
S
V
P
Q
I
T
S
L
A
R
E
L
R
K
R
G
V
P
I
----
P
P
D
V
L
T
I
E
E
A
K
E
H
I
L
R
Y
L
R
G
T
--------------------------------------------------
7
PsiBlast_PDB
66.85
39%
-132
- C1 -
-
3GFO
-
ECFA3_CLOP1
A:
[8-254]
--
L
K
V
E
E
L
N
Y
N
Y
S
D
G
T
----
H
A
L
K
G
I
N
M
N
I
K
R
G
E
V
T
A
I
L
G
G
N
G
V
G
K
S
T
L
F
Q
N
F
N
G
I
L
K
P
S
S
G
R
I
L
F
D
--------
N
K
P
I
--
D
Y
S
R
K
-
G
-
I
M
K
L
R
E
-
S
I
G
I
V
F
Q
----
D
P
D
N
Q
L
F
S
--
A
-
S
V
Y
Q
D
V
S
F
G
A
-
V
N
M
K
L
P
E
D
E
I
R
K
R
V
D
N
A
L
K
R
T
G
I
--
E
H
L
K
D
K
P
T
H
C
L
S
F
G
Q
K
K
R
V
A
I
A
G
V
L
V
M
E
P
K
V
L
I
L
D
E
P
T
A
G
L
D
P
M
G
V
S
E
I
M
K
L
L
--
V
E
M
Q
K
E
L
G
I
T
I
I
I
A
T
H
D
I
D
I
V
P
L
Y
C
D
N
V
F
V
M
K
E
G
R
V
I
L
Q
G
N
P
K
E
V
F
---------
A
E
K
E
V
I
R
K
V
N
L
R
L
P
R
I
G
H
L
M
E
I
-----------------------------------------------------------------------------------
26
PsiBlast_CBE
65.28
36%
-110
- C1 -
-
5X40
2
CBIO_RHOCB
B:
[27-289]
----------------
P
G
G
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
----------
G
T
A
T
G
H
S
R
K
-
D
-
L
T
G
W
R
R
-
R
V
G
L
V
L
Q
----
D
A
D
D
Q
L
F
A
--
T
-
T
V
F
E
D
V
S
F
G
P
-
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
S
I
S
-
D
-
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
Q
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
---
R
G
L
R
A
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
R
V
L
A
E
G
A
A
E
A
V
L
---------
S
D
R
A
T
L
A
K
V
A
L
R
P
P
L
V
I
D
L
A
--
L
L
A
R
D
H
G
L
LAPE
A
P
L
P
K
T
R
D
A
L
A
A
Q
M
A
G
W
------------------------------------------------------
156
HHSearch
64.60
36%
-121
- C1 -
-
5X40
2
CBIO_RHOCB
A:
[16-268]
-
I
L
A
A
E
A
L
T
Y
A
F
P
G
----
G
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
--------
G
T
A
T
G
H
S
--
R
K
-
D
-
L
T
G
W
R
R
-
R
V
G
L
V
L
Q
----
D
A
D
D
Q
L
F
A
--
T
-
T
V
F
E
D
V
S
F
G
P
-
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
S
I
S
--
D
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
Q
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
--
R
G
L
R
A
-
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
R
V
L
A
E
G
A
A
E
A
V
L
---------
S
D
R
A
T
L
A
K
V
A
L
R
P
P
L
V
I
D
L
A
L
L
A
R
D
H
G
L
-----------------------------------------------------------------------------
13
PsiBlast_PDB
63.62
36%
-105
- C1 -
-
5X40
2
CBIO_RHOCB
A:
[27-289]
----------------
P
G
G
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
----------
G
T
A
T
G
H
S
R
K
-
D
-
L
T
G
W
R
R
-
R
V
G
L
V
L
Q
----
D
A
D
D
Q
L
F
A
--
T
-
T
V
F
E
D
V
S
F
G
P
-
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
S
I
S
-
D
-
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
Q
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
---
R
G
L
R
A
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
R
V
L
A
E
G
A
A
E
A
V
L
---------
S
D
R
A
T
L
A
K
V
A
L
R
P
P
L
V
I
D
L
A
--
L
L
A
R
D
H
G
L
LAPE
A
P
L
P
K
T
R
D
A
L
A
A
Q
M
A
G
W
------------------------------------------------------
154
HHSearch
62.98
37%
-116
- C1 -
-
5X3X
-
CBIO_RHOCB
B:
[4-255]
-
I
L
A
A
E
A
L
T
Y
A
F
P
G
----
G
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
--------
G
T
A
T
G
H
S
--
R
K
-
D
-
L
T
G
W
R
R
-
R
V
G
L
V
L
Q
----
D
A
D
D
Q
L
F
A
--
T
-
T
V
F
E
D
V
S
F
G
P
-
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
S
I
S
--
D
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
E
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
--
R
G
L
R
A
-
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
R
V
L
A
E
G
A
A
E
A
V
L
---------
S
D
R
A
T
L
A
K
V
A
L
R
P
P
L
V
I
D
L
A
L
L
A
R
D
H
G
------------------------------------------------------------------------------
11
PsiBlast_PDB
61.32
37%
-105
- C1 -
-
5X3X
-
CBIO_RHOCB
A:
[15-277]
----------------
P
G
G
V
K
A
L
D
D
L
S
L
A
V
P
K
G
E
S
L
A
I
L
G
P
N
G
A
G
K
S
T
L
L
L
H
L
N
G
T
L
R
P
Q
S
G
R
V
L
L
G
----------
G
T
A
T
G
H
S
R
K
-
D
-
L
T
G
W
R
R
-
R
V
G
L
V
L
Q
----
D
A
D
D
Q
L
F
A
--
T
-
T
V
F
E
D
V
S
F
G
P
-
L
N
L
G
L
S
E
A
E
A
R
A
R
V
E
E
A
L
A
A
L
S
I
S
-
D
-
L
R
D
R
P
T
H
M
L
S
G
G
Q
K
R
R
V
A
I
A
G
A
V
A
M
R
P
E
V
L
L
L
D
E
P
T
A
G
L
D
L
A
G
T
E
Q
L
L
T
L
L
---
R
G
L
R
A
A
G
M
T
L
V
F
S
T
H
D
V
E
L
A
A
A
L
A
D
R
V
A
L
F
R
T
G
R
V
L
A
E
G
A
A
E
A
V
L
---------
S
D
R
A
T
L
A
K
V
A
L
R
P
P
L
V
I
D
L
A
--
L
L
A
R
D
H
G
L
LAPE
A
P
L
P
K
T
R
D
A
L
A
A
Q
M
A
G
W
------------------------------------------------------
166
Fugue
59.76
25%
-129
- C1 -
-
3TUZ
1
METN_ECOLI
H:
[23-362]
H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
-
T
R
T
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
--------
G
Q
E
L
T
T
-
L
S
E
S
-
E
-
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
----
H
F
N
L
-
L
S
S
--
R
-
T
V
F
G
N
V
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
-
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
--
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
SHPKTPLAQ
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
----
L
R
L
E
F
T
G
Q
S
V
D
A
P
L
L
S
E
T
A
R
R
F
N
V
N
NNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV
80
PsiBlast_CBE
59.22
31%
-142
- C1 -
-
3TUI
1
METN_ECOLI
H:
[42-254]
--------------------
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
--------
G
Q
E
L
T
T
L
S
E
S
E
---
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
----
H
F
N
L
-
L
S
S
--
R
-
T
V
F
G
N
V
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
-
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
--
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---------
S
H
-------------------------------------------------------------------------------------------------------
79
PsiBlast_CBE
57.99
31%
-141
- C1 -
-
3TUZ
1
METN_ECOLI
C:
[42-254]
--------------------
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
--------
G
Q
E
L
T
T
L
S
E
S
E
---
L
T
K
A
R
R
-
Q
I
G
M
I
F
Q
----
H
F
N
L
-
L
S
S
--
R
-
T
V
F
G
N
V
A
L
P
L
-
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
-
D
K
H
-
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
--
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---------
S
H
-------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
49.37
39%
-64
- C1 -
-
4HLU
1
ECFA2_THEMA
A:
[9-232]
------
N
V
S
H
I
F
H
R
G
T
P
L
E
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
---------------
D
V
L
Y
D
G
E
R
K
-
K
-
G
Y
E
I
R
R
-
N
I
G
I
A
F
Q
----
Y
P
E
D
Q
F
F
A
--
E
-
R
V
F
D
E
V
A
F
A
V
-
K
N
F
-
Y
P
D
R
D
P
V
P
L
V
K
K
A
M
E
F
V
G
L
D
F
D
S
F
K
D
R
V
P
F
F
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
E
K
W
---
K
T
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
R
M
E
F
L
---------
E
K
Y
D
-----------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
49.22
39%
-63
- C1 -
-
4HLU
1
ECFA2_THEMA
B:
[9-232]
------
N
V
S
H
I
F
H
R
G
T
P
L
E
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
---------------
D
V
L
Y
D
G
E
R
K
-
K
-
G
Y
E
I
R
R
-
N
I
G
I
A
F
Q
----
Y
P
E
D
Q
F
F
A
--
E
-
R
V
F
D
E
V
A
F
A
V
-
K
N
F
-
Y
P
D
R
D
P
V
P
L
V
K
K
A
M
E
F
V
G
L
D
F
D
S
F
K
D
R
V
P
F
F
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
EK
W
---
K
T
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
R
M
E
F
L
---------
E
K
Y
D
-----------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
45.95
37%
-9
- C1 -
-
4YMU
1
?
J:
[20-224]
-------------------------
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
----------
G
V
K
I
N
N
G
K
V
-
N
-
I
N
K
V
R
Q
-
K
V
G
M
V
F
Q
HFNL
F
P
H
L
--------
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
-
D
K
K
-
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
--
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
45.68
39%
-62
- C1 -
-
4ZIR
2
ECFA2_THEMA
A:
[8-229]
------
N
V
S
H
I
F
H
R
G
T
P
L
E
K
K
A
L
E
N
V
S
L
V
I
N
E
G
E
C
L
L
V
A
G
N
T
G
S
G
K
S
T
L
L
Q
I
V
A
G
L
I
E
P
T
S
G
---------------
D
V
L
Y
D
G
E
---
K
-
G
Y
E
I
R
R
-
N
I
G
I
A
F
Q
----
Y
P
E
D
Q
F
F
A
--
E
-
R
V
F
D
E
V
A
F
A
V
-
K
N
F
-
Y
P
D
R
D
P
V
P
L
V
K
K
A
M
E
F
V
G
L
D
F
D
S
F
K
D
R
V
P
F
F
L
S
G
G
E
K
R
R
V
A
I
A
S
V
I
V
H
E
P
D
I
L
I
L
D
E
P
L
V
G
L
D
R
E
G
K
T
D
L
L
R
I
V
E
K
W
---
K
T
L
G
K
T
V
I
L
I
S
H
D
I
E
T
V
I
N
H
V
D
R
V
V
V
L
E
K
G
K
K
V
F
D
G
T
R
M
E
F
L
---------
E
K
-------------------------------------------------------------------------------------------------------
60
PsiBlast_CBE
45.65
36%
-17
- C1 -
-
3C41
2
?
K:
[22-226]
-------------------------
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
----------
G
I
N
L
K
A
K
D
T
-
N
-
L
N
K
V
R
E
-
E
V
G
M
V
F
Q
RFNL
F
P
H
M
--------
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
-
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
--
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
45.07
37%
-9
- C1 -
-
4YMU
1
?
A:
[20-224]
-------------------------
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
----------
G
V
K
I
N
N
G
K
V
-
N
-
I
N
K
V
R
Q
-
K
V
G
M
V
F
Q
HFNL
F
P
H
L
--------
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
-
D
K
K
-
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
--
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
------------------------------------------------------------------------------------------------------------------
61
PsiBlast_CBE
44.79
36%
-10
- C1 -
-
3C41
2
?
J:
[22-226]
-------------------------
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
----------
G
I
N
L
K
A
K
D
T
-
N
-
L
N
K
V
R
E
-
E
V
G
M
V
F
Q
RFNL
F
P
H
M
--------
T
V
L
N
N
I
T
L
A
P
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
-
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
--
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
------------------------------------------------------------------------------------------------------------------
59
PsiBlast_CBE
44.77
36%
-20
- C1 -
-
3TIF
4
Y796_METJA
A:
[20-223]
---------------------
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--------
N
I
K
T
N
-
D
L
D
D
D
-
E
-
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q---
F
N
L
I
P
L
L
T
A
L
E
-
N
V
E
L
P
L
I
F
K
Y
-
R
G
-
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
--
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
-
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
----------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
43.77
37%
-9
- C1 -
-
4YMV
1
?
J:
[20-224]
-------------------------
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
----------
G
V
K
I
N
N
G
K
V
-
N
-
I
N
K
V
R
Q
-
K
V
G
M
V
F
Q
HFNL
F
P
H
L
--------
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
-
D
K
K
-
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
--
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
43.70
36%
-23
- C1 -
-
1L2T
3
Y796_METJA
A:
[20-223]
---------------------
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--------
N
I
K
T
N
-
D
L
D
D
D
-
E
-
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q---
F
N
L
I
P
L
L
T
A
L
E
-
N
V
E
L
P
L
I
F
K
Y
-
R
G
-
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
--
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
-
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
----------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
43.35
37%
-5
- C1 -
-
4YMV
1
?
A:
[20-224]
-------------------------
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
----------
G
V
K
I
N
N
G
K
V
-
N
-
I
N
K
V
R
Q
-
K
V
G
M
V
F
Q
HFNL
F
P
H
L
--------
T
A
I
E
N
I
T
L
A
P
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
-
D
K
K
-
D
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
--
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
41.58
36%
-26
- C1 -
-
1L2T
3
Y796_METJA
B:
[20-223]
---------------------
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--------
N
I
K
T
N
-
D
L
D
D
D
-
E
-
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q---
F
N
L
I
P
L
L
T
AL
E
-
N
V
E
L
P
L
I
F
K
Y
-
R
G
-
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
--
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
-
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
----------------------------------------------------------------------------------------------------------------------------
58
PsiBlast_CBE
39.08
36%
-21
- C1 -
-
3TIF
3
Y796_METJA
B:
[20-223]
---------------------
A
L
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
--------
N
I
K
T
N
-
D
L
D
D
D
-
E
-
L
T
K
I
R
R
D
K
I
G
F
V
F
Q
Q---
F
N
L
I
P
L
L
T
AL
E
-
N
V
E
L
P
L
I
F
K
Y
-
R
G
-
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
-
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
--
K
K
L
N
E
E
D
G
K
T
V
V
V
V
T
H
D
I
-
N
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
----------------------------------------------------------------------------------------------------------------------------
115
PsiBlast_CBE
32.18
35%
31
- C1 -
-
1B0U
1
HISP_SALTY
A:
[45-243]
---------------------------------------------
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
GQNI
N
L
V
R
D
K
D
G
Q
L
K
V
A
D
K
-
N
Q
L
R
L
L
R
T
-
R
L
T
M
V
F
Q
------
H
F
N
L
W
S
--
H
M
T
V
L
E
N
V
M
E
A
P
I
Q
V
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
-
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
--
Q
Q
L
A
E
E
G
K
-
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
---------
G
N
-------------------------------------------------------------------------------------------------------