@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZ23: (2018-01-12 )
MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFGYAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNTALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQPARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDVQLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTINGLLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTETLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQITITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQLVRLHKGKLEVESELGKGTKFAVRLPDVEIKKE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220-.......230.......240.......250---------------------------------------------------------------------------------------------------------------........260.......270.......280-....--..---.290..-.....300.......310.-------......320.......330.......340-....---.....350----......---.--.--360..-..--....370.......380.-...----.----..---390......--------------..400.......410.......420.......430.......440.......450.......460.......470.......480
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
R
Y
L
Y
Q
Q
L
L
A
F
C
G
M
V
A
L
I
L
L
I
VGV
S
F
T
Q
L
T
K
Q
T
IEEN
N
Y
Q
Q
L
F
G
Y
A
E
S
V
E
K
T
T
Q
T
Y
A
D
TLPQF
S
Q
D
Q
A
F
Q
N
A
L
L
L
T
E
Q
V
LTEQNV
N
F
I
F
IDKN
E
R
V
I
YPTN
T
A
L
L
N
F
T
L
T
A
D
Q
W
K
N
L
RNG
R
Q
EKFTSNKN
I
L
G
QAQA
T
S
Y
A
L
V
P
F
NLNH
E
F
Y
G
A
L
V
VSQ
P
A
RNIDNSVR
P
I
T
L
N
L
F
K
G
F
I
F
S
S
I
V
A
V
I
A
S
Y
A
F
A
A
F
Q
V
K
R
I
N
R
L
R
N
A
T
K
E
VTNG
N
F
D
V
Q
L
PV-H
D
K
D
E
F
D
E
L
A
D
D
F
N
K
M
T
N
S
L
K
E
S
Q
A
E
I
E
E
----------------------------------------------------------------------------------------------------------------
Q
E
N
R
R
R
Q
F
M
A
DASHEMRT
P
L
T
T
I
N
G
L
L
EGLE-YNAI--PE---
N
Q
R
E
N
A
-
I
K
L
M
KN
E
T
E
R
L
I
R
L
V
NENL-------
D
Y
E
K
I
R
T
N
Q
I
S
M
V
I
K
KFN
G
T
E
T
L
K
N
I
V
---
A
Q
L
E
---
A
K
A
EAAG-----
D
T
L
T
L
K
---A--V--D-DI
D
-
V
Y--A
D
Y
D
R
F
V
Q
I
M
V
N
I
I
Q
N
A
I
-QFT----E----N
G
---
Q
-
I
T
I
T
LEK--------------G
Y
L
E
T
I
I
T
I
EDTGIGM
S
E
Q
Q
M
K
S
I
W
D
R
Y
YKVDPSRKNTKYGESGL
G
L
P
I
V
Q
Q
L
V
R
LHKG
K
L
E
V
E
S
ELGKG
T
K
F
A
V
RLP
D
V
E
IKKE
34
HHSearch
86.14
26%
-
- C1 -
-
4I5S
-
?
B:
[28-434]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
F
L
N
Y
R
E
Y
K
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
L
K
V
-
E
D
N
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
MT
D
G
V
L
A
T
D
RSGKITVIN
D
M
A
Q
K
Q
L
NVT
R
E
Q
A
L
E
CNILDILDDDSY
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
RRDEYD
E
F
I
T
L
R
I
R
F
A
L
N
R
R
ESGFIS
G
L
I
A
V
L
H
DA
T
E
Q
E
K
E
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
D
-
D
G
A
L
--
T
E
---
S
V
A
P
S
F
-
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
-------
S
L
S
R
I
D
N
Q
T
S
H
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
I
L
---
D
R
F
D
---
Q
I
Q
S
Q
Q
-------
E
I
I
R
D
---
Y
--
P
D-
K
-
S
V
W
-
I
E
--
I
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
-
K
Y
S
P---
D
----
G
G
---
K
-
V
T
I
T
M
Q
T
--------------
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
-------
T
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
Y
E
-----
57
Fugue
69.28
22%
-
- C1 -
-
4I5S
-
?
A:
[37-432]
-----------------------------
N
N
N
Q
V
K
Q
L
N
A
K
V
R
S
L
I
T
G
H
Y
T
D
K
L
K
V
E
D
N
--------------------------------
S
D
L
S
E
L
V
N
N
V
N
D
L
S
E
V
F
R
L
T
H
E
N
L
A
Q
E
K
N
R
L
T
S
I
L
S
Y
M
T
D
--
G
V
L
A
T
D
R
S
G
-----------
K
I
T
V
I
N
D
M
A
Q
K
Q
L
N
V
T
R
E
Q
A
L
E
----------
C
N
I
L
D
I
L
D
D
D
S
Y
T
Y
N
D
L
I
T
K
T
P
E
I
V
L
T
R
R
D
E
Y
D
E
F
I
T
L
-
R
I
R
F
A
L
N
R
R
E
S
G
F
I
S
G
L
I
A
V
L
H
D
A
T
E
Q
E
K
----------------------------------------------------------------------------------------------------------------
E
E
R
E
R
R
L
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
D
-
D
G
A
L
--
T
E
---
S
V
A
P
S
F
-
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
-------
S
L
S
R
S
H
L
D
V
-----
E
L
T
N
F
T
A
F
M
N
Y
I
L
---
D
R
F
D
---
Q
I
Q
S
Q
Q
S
-----
T
E
I
I
R
D
---
Y
--
P
--
D
K
S
V
W
-
I
E
--
I
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
-
K
Y
S
P---
D
----
G
G
---
K
-
V
T
I
T
M
Q
T
--------------
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
--------
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
-------
6
PsiBlast_PDB
63.14
29%
-
- C1 -
-
4Q20
-
DIVL_CAUCR
A:
[526-758]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
A
D
R
S
A
A
L
A
E
----------------------------------------------------------------------------------------------------------------
A
E
R
L
K
R
D
F
V
G
N
V
S
Y
E
L
R
T
P
L
T
T
I
I
G
Y
S
E
L
L
E
R
A
D
----
S
E
---
R
G
R
-
N
H
-
V
A
A
V
R
A
A
A
T
Q
L
A
R
S
I
D
D
V
L
-------
D
M
A
Q
I
D
A
G
E
M
A
L
E
I
E
D
I
R
V
S
D
L
L
L
N
A
Q
---
E
R
A
L
---
K
D
A
Q
L
G
G
-----
V
T
L
A
V
E
---
C
--
E
--
E
-
D
V
G
L
I
R
--
G
D
G
K
R
L
A
Q
T
L
D
H
L
V
E
N
A
L
R
Q
T
P
----
P
----
G
G
---
R
-
V
T
L
S
A
R
R
--------------
A
L
G
E
V
R
L
D
V
S
D
T
G
R
G
V
P
F
H
V
Q
A
H
I
F
D
R
F
V
G
R
D
-------
R
G
G
P
G
L
G
L
A
L
V
K
A
L
V
E
L
H
G
G
W
V
A
L
E
S
E
P
G
N
G
S
T
F
T
C
H
L
P
E
T
Q
----
43
HHSearch
60.66
30%
24
- C1 -
-
5C93
1
?
A:
[10-241]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
-
D
G
A
W
K-
D
P
---
E
V
A
P
G
F
-
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
-------
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
---
D
R
F
D
---
M
I
L
K
K
D
D
NPA
K
Y
Y
T
I
K
R
E
---
F
T
-
K
--
R
-
D
L
W
-
V
E
--
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
-
K
Y
S
P---
D
----
G
G
---
V
-
V
T
C
R
L
L
E
--------------
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
A
-----
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-----
10
PsiBlast_PDB
59.37
27%
10
- C1 -
-
4JAV
1
?
A:
[20-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
--
Y
N
S
L
--
G
E
LD
L
S
T
L
K
E
F
-
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
-------
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
NV
P
--
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
KDAP
D
K
---
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
-
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
-------
48
HHSearch
58.71
30%
20
- C1 -
-
4U7O
1
?
A:
[32-263]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
-
D
G
A
W
K-
D
P
---
E
V
A
P
G
F
-
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
-------
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
---
D
R
F
D
---
M
I
L
K
K
D
D
NPA
K
Y
Y
T
I
K
R
E
---
F
T
-
K
--
R
-
D
L
W
-
V
E
--
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
-
K
Y
S
P---
D
----
G
G
---
V
-
V
T
C
R
L
L
E
--------------
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
------
Q
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
Y
E
-----
11
PsiBlast_PDB
58.61
27%
17
- C1 -
-
2C2A
1
?
A:
[20-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
--
Y
N
S
L
--
G
E
LDL
S
T
L
K
E
F
-
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
-------
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
NV
P
--
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
KDAP
D
K
---
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
----------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
-------
3
PsiBlast_PDB
56.41
30%
-
- C1 -
-
4U7N
-
?
A:
[386-608]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
-
D
G
A
W
--
K
D
---
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
-------
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
---
D
R
F
D
M
I
L
K
K
D
D
N
--------
Y
Y
T
I
K
R
E
F
T
--
K
--
R
-
D
L
W
-
V
E
--
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
-
K
Y
S
----
P
----
D
G
---
G
V
V
T
C
R
L
L
E
--------------
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
------------
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
-------
13
PsiBlast_PDB
56.12
24%
2
- C1 -
-
4BIV
2
CPXA_ECOLI
A:
[29-293]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
A
R
K
L
K
N
A
A
D
E
V
A
Q
G
N
L
R
-
Q
H
P
------
E
L
E
A
G
P
Q
E
F
L
A
A
G
A
S
F
N
Q
M
V
T
A
L
E
R
----------------------------------------------------------------------------------------------------------------
M
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
-
L
G
T
A
L
L
-
R
R
R
S
--
G
E
---
S
K
E
----
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
-------
V
M
S
R
-
N
Q
Q
K
N
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
---
D
N
A
A
---
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
F
--
P
--
P
--
G
-
P
W
P
-
L
Y
--
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
-
R
Y
S
----
H
----
T
K
I
--
E
-
V
G
F
A
V
D
K
--------------
D
G
I
--
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
-
D
R
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
W
L
P
-------
47
HHSearch
56.06
26%
58
- C1 -
-
4JAV
1
?
A:
[17-248]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
-
N
S
L
G
EL
D
L
---
S
T
L
K
E
F
-
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
-------
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
--
N
VP
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
K---
D
A
P
D
K
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
-
E
V
P
G
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
D
-----
9
PsiBlast_PDB
55.52
27%
20
- C1 -
-
3DGE
2
?
A:
[20-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
--
Y
N
S
L
--
G
E
LD
L
S
T
L
K
E
F
-
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
-------
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
NV
P
--
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
KDAP
D
K
---
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
-
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
-------
2
PsiBlast_PDB
54.87
30%
30
- C1 -
-
5C93
1
?
A:
[10-239]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
-
D
G
A
W
--
K
D
---
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
-------
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
---
D
R
F
D
M
I
L
K
K
D
D
N
P
A
-----
K
Y
Y
T
I
K
R
E
F
T
--
K
--
R
-
D
L
W
-
V
E
--
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
-
K
Y
S
----
P
----
D
G
---
G
V
V
T
C
R
L
L
E
--------------
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
A
----
Q
-
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
-------
7
PsiBlast_PDB
54.00
26%
13
- C1 -
-
4JAS
1
?
A:
[20-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
--
Y
N
S
L
--
G
E
---
L
D
-----
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
NV
P
--
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
KDAP
D
K
---
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
S
L
T
Y
E
V
P
G
-
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
-------
46
HHSearch
53.98
26%
46
- C1 -
-
2C2A
1
?
A:
[17-249]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
A
E
T
I
Y
-
N
S
L
G
EL
D
L
---
S
T
L
K
E
F
-
L
E
V
I
I
D
Q
S
N
H
L
E
N
L
L
N
E
L
L
-------
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
--
N
VP
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
K---
D
A
P
D
K
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
----------
T
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
K
D
R
----
8
PsiBlast_PDB
53.51
26%
14
- C1 -
-
4JAU
1
?
A:
[20-246]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
V
I
K
G
Y
A
E
M
I
--
Y
N
S
L
--
G
E
---
L
D
-----
L
S
T
L
K
E
F
L
E
T
I
I
E
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
K
S
L
Q
I
N
R
E
K
V
D
L
C
D
L
V
E
S
A
V
---
N
A
I
K
---
E
F
A
S
S
H
N
-----
V
N
V
L
F
E
---
S
NV
P
--
C
-
P
V
E
-
A
Y
--
I
D
P
T
R
I
R
Q
V
L
L
N
L
L
N
N
G
V
-
K
Y
S
----
K
KDAP
D
K
---
Y
-
V
K
V
I
L
D
E
--------------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
K
D
R
I
F
E
Q
F
Y
R
V
D
S
----------
G
L
G
L
A
I
T
K
E
I
V
E
L
H
G
G
R
I
W
V
E
S
E
V
G
K
G
S
R
F
F
V
W
I
P
-------
59
Fugue
52.90
21%
-107
- C1 -
-
1ID0
1
A:
[1-146]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
L
H
P
V
A
P
L
L
D
N
L
T
---
S
A
L
N
---
K
V
Y
Q
R
K
G
-----
V
N
I
S
L
D
---
I
--
S
--
P
-
E
I
S
-
F
V
--
G
E
Q
N
D
F
V
E
V
M
G
N
V
L
D
N
A
C
-
K
Y
C
----
L
----
E
----
F
-
V
E
I
S
A
R
Q
--------------
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
L
S
K
R
E
V
I
F
D
R
G
Q
R
V
D
T
L
R
P
G
Q
-----
G
V
G
L
A
V
A
R
E
I
T
E
Q
Y
E
G
K
I
V
A
G
E
S
M
L
G
G
A
R
M
E
V
I
F
G
R
Q
H
----
4
PsiBlast_PDB
52.04
30%
27
- C1 -
-
4U7O
1
?
A:
[32-261]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
D
R
K
Q
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
L
R
S
Y
I
E
A
L
S
-
D
G
A
W
--
K
D
---
P
E
V
A
P
G
F
L
K
V
T
Q
E
E
T
D
R
M
I
R
M
I
N
E
L
L
-------
S
L
S
R
M
D
S
G
T
T
R
V
D
M
E
L
V
N
I
N
E
M
F
N
Y
V
L
---
D
R
F
D
M
I
L
K
K
D
D
N
P
A
-----
K
Y
Y
T
I
K
R
E
F
T
--
K
--
R
-
D
L
W
-
V
E
--
I
D
T
D
K
F
T
Q
V
L
D
N
I
M
N
N
A
I
-
K
Y
S
----
P
----
D
G
---
G
V
V
T
C
R
L
L
E
--------------
T
H
N
Q
V
I
I
S
I
S
D
Q
G
L
G
I
P
R
A
D
L
G
H
V
F
D
R
F
F
R
V
D
K
-----
Q
-
G
G
T
G
L
G
L
A
I
S
K
E
V
V
Q
M
L
G
G
R
I
W
V
D
S
V
E
G
K
G
S
T
F
Y
I
S
L
P
-------
1
PsiBlast_PDB
50.57
30%
-
- C1 -
-
4I5S
-
?
A:
[211-432]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
S
N
V
S
H
E
L
R
T
P
L
T
S
V
K
S
Y
L
E
A
L
D
-
D
G
A
L
--
T
E
---
S
V
A
P
S
F
-
I
K
V
S
L
D
E
T
N
R
M
M
R
M
I
T
D
L
L
-------
S
L
S
R
-----
S
H
L
D
V
E
L
T
N
F
T
A
F
M
N
Y
I
L
D
R
F
D
Q
I
Q
---
S
Q
Q
S
T
---------
E
I
I
R
---
D
--
Y
--
P
-
D
K
S
-
V
W
I
E
I
D
T
D
K
M
T
Q
V
I
D
N
I
L
N
N
A
I
-
K
Y
S
P---
D
----
G
G
---
K
-
V
T
I
T
M
Q
T
--------------
T
D
T
Q
L
I
L
S
I
S
D
Q
G
L
G
I
P
K
K
D
L
P
L
I
F
D
R
F
Y
R
V
D
K
A
R
--------
G
L
G
L
A
I
A
K
E
I
V
K
Q
H
K
G
F
I
W
A
N
S
E
E
G
E
G
S
T
F
T
I
V
L
P
-------
35
HHSearch
48.68
24%
63
* C1 *
-
4BIV
2
CPXA_ECOLI
A:
[29-297]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
P
A
R
K
L
K
N
A
A
D
E
V
A
Q
G
N
L
R
Q
H
P
E
L
E
A
G
P
Q
E
F
L
A
A
G
A
S
F
N
Q
M
V
T
A
L
E
R
-----------------------------------------------------------------------------------------------------------------------
M
M
T
S
Q
Q
R
L
L
S
D
I
S
H
E
L
R
T
P
L
T
R
L
Q
L
G
T
A
L
L
R
-
R
R
S
G
--
E
-------
S
K
E
-
L
E
R
I
E
T
E
A
Q
R
L
D
S
M
I
N
D
L
L
-------
V
M
S
R
N
Q
Q
K
N
-
A
L
V
S
E
T
I
K
A
N
Q
L
W
S
E
V
L
---
D
N
A
A
---
F
E
A
E
Q
M
G
-----
K
S
L
T
V
N
---
F
--
P
--
P
G
P
W
P
-
L
Y
--
G
N
P
N
A
L
E
S
A
L
E
N
I
V
R
N
A
L
-
R
Y
S
----
H
-----
T
---
K
-
I
E
V
G
F
A
V
--------------
D
K
D
G
I
T
I
T
V
D
D
D
G
P
G
V
S
P
E
D
R
E
Q
I
F
R
P
F
Y
R
T
D
E
A
R
D
R
-
E
S
G
G
T
G
L
G
L
A
I
V
E
T
A
I
Q
Q
H
R
G
W
V
K
A
E
D
S
P
L
G
G
L
R
L
V
I
W
L
P
L
Y
K
R
---
52
HHSearch
48.58
21%
8
- C1 -
-
5IDJ
1
?
A:
[7-241]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
A
I
G
Q
L
A
G
G
V
A
H
D
F
N
N
L
L
T
A
I
Q
L
R
L
D
Q
L
L
-
H
R
H
P
--
V
G
---
D
P
S
Y
E
G
-
L
N
E
I
R
Q
T
G
V
R
A
A
D
L
V
R
K
L
L
-------
A
F
S
R
K
Q
T
----
V
Q
R
E
V
L
D
L
G
E
L
I
S
E
F
E
---
V
L
L
R
---
R
L
L
-
R
E
D
-----
V
K
L
I
T
D
---
Y
--
G
R
-
D
-
L
P
Q
-
V
R
--
A
D
K
S
Q
L
E
T
A
V
M
N
L
A
V
N
A
R
-
D
A
V
RAAK
G
----
G
G
---
V
-
V
R
I
R
T
A
R
L
T
R
D
E
A
I
Q
L
GFPAA
D
G
D
T
A
F
I
E
V
S
D
D
G
P
G
I
P
P
D
V
M
G
K
I
F
D
P
F
F
T
T
K
P
-----
V
G
E
G
T
G
L
G
L
A
T
V
Y
G
I
V
K
Q
S
D
G
W
I
H
V
H
S
R
P
N
E
G
A
A
F
R
I
F
L
P
V
Y
E
----