@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZ55: (2018-01-12 )
MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEGAEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTHELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAASKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRVGEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG
Atome Classification :
(30 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MY
K
E
LEN
K
V
A
V
V
TGGSK
G
I
G
T
A
I
A
Q
R
FGKE
K
M
N
V
V
V
N
YNSD
K
E
G
A
E
K
A
V
K
A
I
E
E
AGG
K
A
V
S
V
Q
ADV
S
S
E
E
G
I
Q
R
L
L
D
T
A
L
E
NFG
T
L
D
V
W
VNNAGMENQHPTHEL
S
L
E
D
W
E
R
V
L
K
V
N
L
T
G
V
F
IG
T
K
A
A
L
N
Y
F
TENNKKG
N
I
I
N
M
S
S
V
H
EQIPW
P
T
F
A
H
YAASKG
G
V
K
L
F
T
E
T
V
A
M
EYAPKG
I
R
INSIGPGAIRTPINAAKFD
D
P
E
Q
K
E
L
L
E
SMIPLGRVG
E
P
K
E
I
A
A
T
A
A
W
LASDESS
Y
V
T
G
I
T
L
F
ADG
G
M
T
L
Y
PSFQGGKG
9
PsiBlast_PDB
93.37
61%
-59
- C1 -
-
1G6K
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
36
PsiBlast_CBE
92.71
61%
-62
- C1 -
-
1G6K
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
38
PsiBlast_CBE
92.53
61%
-59
- C1 -
-
1G6K
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
32
PsiBlast_CBE
92.48
61%
-55
- C1 -
-
1RWB
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
37
PsiBlast_CBE
92.26
61%
-62
- C1 -
-
1G6K
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
A
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
6
PsiBlast_PDB
91.94
62%
-57
- C1 -
-
1GEE
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
2
PsiBlast_PDB
91.91
62%
-57
- C1 -
-
3AUT
-
DHG4_BACME
A:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
5
PsiBlast_PDB
91.86
62%
-55
- C1 -
-
3AY7
-
DHG4_BACME
A:
[9-267]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
A
--
3
PsiBlast_PDB
91.79
62%
-56
- C1 -
-
3AUU
1
DHG4_BACME
A:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
7
PsiBlast_PDB
91.74
61%
-59
- C1 -
-
1RWB
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
30
PsiBlast_CBE
91.70
61%
-55
- C1 -
-
1RWB
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
1
PsiBlast_PDB
91.33
62%
-58
- C- -
-
3AUS
-
DHG4_BACME
A:
[1-261]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
29
PsiBlast_CBE
91.28
62%
-57
- C1 -
-
1GEE
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
24
PsiBlast_CBE
90.90
62%
-59
- C1 -
-
3AY6
3
DHG4_BACME
C:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
27
PsiBlast_CBE
90.82
62%
-57
- C1 -
-
1GEE
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
4
PsiBlast_PDB
90.77
62%
-60
- C1 -
-
3AY6
3
DHG4_BACME
A:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
8
PsiBlast_PDB
90.58
61%
-56
- C1 -
-
1GCO
1
DHG_BACME
A:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
142
HHSearch
90.48
62%
-60
- C1 -
-
1RWB
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
25
PsiBlast_CBE
90.26
62%
-55
- C1 -
-
3AY6
3
DHG4_BACME
B:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
23
PsiBlast_CBE
90.24
62%
-54
- C1 -
-
3AY6
3
DHG4_BACME
D:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
F
G
R
G
35
PsiBlast_CBE
90.19
61%
-56
- C1 -
-
1GCO
1
DHG_BACME
B:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
145
HHSearch
90.16
62%
-59
- C1 -
-
1GEE
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
28
PsiBlast_CBE
90.16
62%
-59
- C1 -
-
1GEE
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
34
PsiBlast_CBE
90.07
61%
-58
- C1 -
-
1GCO
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
31
PsiBlast_CBE
90.04
61%
-60
- C1 -
-
1RWB
1
DHG_BACME
E:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
K
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
L
Y
P
S
F
Q
A
G
R
G
33
PsiBlast_CBE
89.79
61%
-58
- C1 -
-
1GCO
1
DHG_BACME
F:
[1-261]
M
Y
K
D
L
E
G
K
V
V
V
I
T
G
S
S
T
G
L
G
K
S
M
A
I
R
F
A
T
E
K
A
K
V
V
V
N
Y
R
S
K
E
D
E
A
N
S
V
L
E
E
I
K
K
V
G
G
E
A
I
A
V
K
G
D
V
T
V
E
S
D
V
I
N
L
V
Q
S
A
I
K
E
F
G
K
L
D
V
M
I
N
N
A
G
L
E
N
P
V
S
S
H
E
M
S
L
S
D
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
T
V
I
N
M
S
S
V
H
E
K
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
I
N
T
P
I
N
A
E
K
F
A
D
P
E
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
E
P
E
E
I
A
A
V
A
A
W
L
A
S
S
E
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
Q
Y
P
S
F
Q
A
G
R
G
22
PsiBlast_CBE
89.58
62%
-59
- C1 -
-
3AUT
1
DHG4_BACME
B:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
21
PsiBlast_CBE
89.08
62%
-58
- C1 -
-
3AUU
1
DHG4_BACME
B:
[9-269]
M
Y
T
D
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
N
D
I
K
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
M
T
K
Y
P
S
F
Q
A
G
R
G
89
PsiBlast_CBE
63.62
36%
-71
- C1 -
-
3RRO
5
FABG_VIBCH
A:
[7-250]
-
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
S
--
E
S
G
A
Q
A
I
S
D
Y
L
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
-
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
--
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
---------
88
PsiBlast_CBE
62.47
36%
-72
- C1 -
-
3RRO
5
FABG_VIBCH
B:
[7-250]
-
F
M
N
L
E
G
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
I
G
T
A
T
S
--
E
S
G
A
Q
A
I
S
D
Y
L
G
D
N
G
K
G
M
A
L
--
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
G
I
T
R
D
N
L
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
G
M
M
K
K
-
R
Q
G
R
I
I
N
V
G
S
V
V
G
T
M
G
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M
T
K
A
L
N
D
--
E
Q
R
T
A
T
L
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
---------