@TOME V2.3
(Mar 2018)
Ref.
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZ80: (2018-01-13 )
MMEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKEYAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQRVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVPIKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAKRNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDKRVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRTGVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVLDKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNIDGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVERLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNEEVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIENLGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE
Atome Classification :
(36 SA)
.........10........20........30........40........50........60........70..-..-.-...80........90........100.....---.---.--110-........120.......130.......140.......150.......160..---.---.---...170.......180.......190.......200.......210.......220.......230.-.---..-.-.--..240.......250---.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430-........440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......--540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MMEHE
M
T
I
D
E
A
A
K
R
A
E
E
L
R
T
R
L
N
Q
W
S
R
E
Y
YVEDKP
T
V
E
D
Y
VY
D
K
E
Y
A
E
L
V
A
I
E
E
QY
P
D
LITSDS
P
T
Q
R
V
G
G
K
V
-
L
E
-
G
-
F
E
K
V
T
HDIPL
Y
S
L
N
D
VF
S
K
E
E
L
I
A
F
D
Q
R
V
Q
K
---
A
---
V
--
G
R
--
V
V
D
Y
C
CE
L
K
ID
G
L
S
V
S
L
R
YEDG
N
F
V
R
G
ATRGDGTVG
E
N
I
T
E
N
L
K
T
V
R
SVP
I
K
L---K---E---P
M
N
I
E
V
RGECFMP
K
R
S
F
V
QLNQDREAEG
K
D
IFANPRNAAA
G
S
L
R
Q
L
D
S
K
I
TAKRN
L
D
T
F
L
Y
T
V
A-DF-G---PM-Q-A--K
T
Q
Y
D
A
L
E
E
L
E
K
IGF---HT
N
R
E
K
R
L
C
H
S
I
D
E
V
W
S
Y
I
E
E
Y
H
DKRVDLPYEID
G
I
V
I
K
VNE
F
S
LQDQL
G
F
T
I
KAPR
W
A
A
AYKF
P
P
E
E
V
E
T
L
I
E
NIEWTVGRTGVVTPTAIMT
P
V
R
VAG
T
T
V
S
R
A
SLHNG
D
Y
I
K
L
K
D
I
R
LK
D
T
V
L
I
Y
KAGDI
I
P
E
V
S
Q
V
V
LDKRPKDSEEYQLPTHCPVC
G
S
E
L
V
HL
D
E
E
V
A
L
R
CINP-K-C
P
A
Q
M
K
E
G
L
N
H
F
V
SRNAMNIDGL
G
P
R
V
L
E
Q
M
Y
D
K
K
L
V
A
D
V
A
D
L
Y
K
L
T
E
E
E
L
L
T
L
D
K
I
K
E
KSAN
N
I
L
T
AIDNSKD
N
S
V
E
R
L
I
F
G
L
G
I
R
H
V
G
A
K
A
A
K
I
L
A
E
H
FG
D
L
E
T
LS--KSD
Y
E
S
I
I
A
L
D
T
I
G
D
I
I
A
D
S
V
V
T
YFS
N
E
E
V
H
E
L
M
N
E
L
K
Q
AGV
N
F
E
YKGLR
N
A
Q
L
Q
E
V
ESPFKE
K
T
V
V
L
TG
K
L
T
R
F
T
R
E
E
A
K
E
T
I
E
NLGG
K
V
TGSVSKK
T
D
I
V
V
AGEDAGSKL
T
K
A
Q
EL
G
I
E
V
W
T
E
D
Q
M
A
D
A
L
A
KSRSVEE
2
PsiBlast_PDB
77.64
46%
11
- C11 -
-
5TT5
1
DNLJ_ECOLI
A:
[30-606]
----------------
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
P
-
L
A
-
A
-
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
---
L
-------
V
T
W
C
C
E
L
M
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
---
H
---
G
E
NI
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
-
V
L
E
G
---
G
E
-
L
-
P
--
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
---
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
-
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
--
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------------
9
PsiBlast_PDB
77.08
75%
-67
- C11 -
-
4EEQ
2
DNLJ_ENTFA
A:
[5-317]
----
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
76.69
75%
-70
- C11 -
-
4EFE
2
DNLJ_ENTFA
A:
[5-317]
----
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
75.85
75%
-67
- C11 -
-
4EFB
2
DNLJ_ENTFA
A:
[5-317]
----
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
75.57
74%
-68
- C11 -
-
3BA9
5
DNLJ_ENTFA
A:
[5-317]
----
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
HHSearch
75.44
45%
30
- C11 -
-
5TT5
1
DNLJ_ECOLI
A:
[21-606]
-------
M
E
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
P
-
L
A
-
A
-
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
R
L-------------
V
T
W
C
C
E
L
M
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
---
H
---
G
E
NI
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
-
V
L
-
E
---
G
G
E
L
-
P
--
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
---
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
-
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
--
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------------
8
PsiBlast_PDB
75.32
74%
-65
- C11 -
-
1TA8
2
DNLJ_ENTFA
A:
[5-317]
----
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
HHSearch
75.27
44%
19
- C11 -
-
4GLX
3
DNLJ_ECOLI
A:
[3-583]
---------
S
I
E
Q
Q
L
T
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
----
P
-
L
A
-
A
-
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
------------
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
---
H
G
E
N
I
---
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
-
V
L
-
E
---
G
G
-
E
L
P
--
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
---
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
L
I
-
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
--
L
E
A
L
E
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
75.26
74%
-70
- C11 -
-
3BA8
2
DNLJ_ENTFA
A:
[5-317]
----
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
74.98
44%
15
- C11 -
-
4GLX
3
DNLJ_ECOLI
A:
[10-583]
----------------
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
----
P
-
L
A
-
A
-
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
------------
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
---
H
---
G
E
NI
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
-
V
L
E
G
---
G
E
-
L
-
P
--
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
---
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
-
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
--
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
74.79
46%
32
- C11 -
-
2OWO
3
DNLJ_ECOLI
A:
[10-586]
----------------
E
L
R
T
T
L
R
H
H
E
Y
L
Y
H
V
M
D
A
P
E
I
P
D
A
E
Y
D
R
L
M
R
E
L
R
E
L
E
T
K
H
P
E
L
I
T
P
D
S
P
T
Q
R
V
G
A
A
P
-
L
A
-
A
-
F
S
Q
I
R
H
E
V
P
M
L
S
L
D
N
V
F
D
E
E
S
F
L
A
F
N
K
R
V
Q
D
---
R
---
L
KN
N
E
--
K
V
T
W
C
C
E
L
K
L
D
G
L
A
V
S
I
L
Y
E
N
G
V
L
V
S
A
A
T
R
G
D
G
T
T
G
E
D
I
T
S
N
V
R
T
I
R
A
I
P
L
K
L
---
H
---
G
E
NI
P
A
R
L
E
V
R
G
E
V
F
L
P
Q
A
G
F
E
K
I
N
E
D
A
R
R
T
G
G
K
V
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
R
I
T
A
K
R
P
L
T
F
F
C
Y
G
V
G
-
V
L
E
G
---
G
E
-
L
-
P
--
D
T
H
L
G
R
L
L
Q
F
K
K
W
G
L
---
P
V
S
D
R
V
T
L
C
E
S
A
E
E
V
L
A
F
Y
H
K
V
E
E
D
R
P
T
L
G
F
D
I
D
G
V
V
I
K
V
N
S
L
A
Q
Q
E
Q
L
G
F
V
A
R
A
P
R
W
A
V
A
F
K
F
P
A
Q
E
Q
M
T
F
V
R
D
V
E
F
Q
V
G
R
T
G
A
I
T
P
V
A
R
L
E
P
V
H
V
A
G
V
L
V
S
N
A
T
L
H
N
A
D
E
I
E
R
L
G
L
R
I
G
D
K
V
V
I
R
R
A
G
D
V
I
P
Q
V
V
N
V
V
L
S
E
R
P
E
D
T
R
E
V
V
F
P
T
H
C
P
V
C
G
S
D
V
E
R
V
E
G
E
A
V
A
R
C
T
G
G
-
L
I
C
G
A
Q
R
K
E
S
L
K
H
F
V
S
R
R
A
M
D
V
D
G
M
G
D
K
I
I
D
Q
L
V
E
K
E
Y
V
H
T
P
A
D
L
F
K
L
T
A
G
K
L
T
G
L
E
R
M
G
P
K
S
A
Q
N
V
V
N
A
L
E
K
A
K
E
T
T
F
A
R
F
L
Y
A
L
G
I
R
E
V
G
E
A
T
A
A
G
L
A
A
Y
F
G
T
L
E
A
L
E
--
A
A
S
I
E
E
L
Q
K
V
P
D
V
G
I
V
V
A
S
H
V
H
N
F
F
A
E
E
S
N
R
N
V
I
S
E
L
L
A
E
G
V
H
W
P
A
P
---------------------------------------------------------------------------------------------
6
PsiBlast_PDB
74.38
74%
-65
- C11 -
-
3BAA
4
DNLJ_ENTFA
A:
[6-317]
-----
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
74.03
74%
-64
- C11 -
-
3BAB
3
DNLJ_ENTFA
A:
[6-317]
-----
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
60
HHSearch
73.65
75%
-62
- C11 -
-
4LH6
2
DNLJ_ENTFA
A:
[2-323]
-
E
Q
Q
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
73.40
74%
-62
- C11 -
-
4LH6
2
DNLJ_ENTFA
A:
[2-323]
-
E
Q
Q
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
72.80
74%
0
- C- -
-
1TAE
-
DNLJ_ENTFA
A:
[4-324]
---
Q
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
T
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
72.28
74%
-59
- C11 -
-
4LH7
2
DNLJ_ENTFA
A:
[2-322]
-
E
Q
Q
P
L
T
L
T
A
A
T
T
R
A
Q
E
L
R
K
Q
L
N
Q
Y
S
H
E
Y
Y
V
K
D
Q
P
S
V
E
D
Y
V
Y
D
R
L
Y
K
E
L
V
D
I
E
T
E
F
P
D
L
I
T
P
D
S
P
T
Q
R
V
G
G
K
V
-
L
S
-
G
-
F
E
K
A
P
H
D
I
P
M
Y
S
L
N
D
G
F
S
K
E
D
I
F
A
F
D
E
R
V
R
K
---
A
---
I
--
G
K
--
P
V
A
Y
C
C
E
L
K
I
D
G
L
A
I
S
L
R
Y
E
N
G
V
F
V
R
G
A
T
R
G
D
G
T
V
G
E
N
I
T
E
N
L
R
T
V
R
S
V
P
M
R
L
---
T
---
E
---
P
I
S
V
E
V
R
G
E
C
Y
M
P
K
Q
S
F
V
A
L
N
E
E
R
E
E
N
G
Q
D
I
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
T
K
I
V
A
K
R
N
L
N
T
F
L
Y
T
V
A
-
D
F
-
G
---
P
M
-
K
-
A
--
K
T
Q
F
E
A
L
E
E
L
S
A
I
G
F
---
R
T
N
P
E
R
Q
L
C
Q
S
I
D
E
V
W
A
Y
I
E
E
Y
H
E
K
R
S
T
L
P
Y
E
I
D
G
I
V
I
K
V
N
E
F
A
L
Q
D
E
L
G
F
T
V
K
A
P
R
W
A
I
A
Y
K
F
P
P
E
E
A
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
71.17
41%
36
- C11 -
-
1DGS
1
DNLJ_THEFI
A:
[1-581]
-----
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
E
P
T
-
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
E
---
A
--
E
A
--
P
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
--
G
S
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
---
K
---
G
V--
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
-
L
G
-
L
GLE
E
S
-
G
-
L
--
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
---
P
V
E
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
--
V
K
E
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------------
16
PsiBlast_PDB
70.87
42%
33
- C11 -
-
1V9P
1
DNLJ_THEFI
A:
[1-584]
-----
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
E
-
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
A
---
L
--
G
R
KR
P
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
---
K
---
G
V--
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
--
L
-
G
---
L
E
-
E
-
S
GL
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
---
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
--
K
E
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------------
15
PsiBlast_PDB
69.76
41%
45
- C11 -
-
1DGS
1
DNLJ_THEFI
A:
[1-581]
-----
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
E
-
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
E
---
A
--
E
A
--
P
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
---
K
---
G
V--
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
L
G
L
-
G
---
L
E
-
E
-
S
GL
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
PVE
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
---
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
--
K
E
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------------
24
PsiBlast_CBE
69.37
41%
45
- C11 -
-
1DGS
1
DNLJ_THEFI
B:
[1-581]
-----
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
E
-
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
E
---
A
--
E
A
--
P
S
L
Y
T
V
E
H
K
V
D
G
L
S
V
-
L
Y
Y
E
E
G
V
W
S
T
G
S
--
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
---
K
---
G
V--
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
L
G
L
-
G
---
L
E
-
E
-
S
GL
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
PVE
H
C
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
---
R
G
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
L
K
L
D
D
L
T
L
W
G
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
K
E
R
P
I
R
W
P
E
A
C
P
E
C
G
H
R
L
V
--
K
E
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
I
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------------
25
PsiBlast_CBE
69.14
42%
41
- C11 -
-
1V9P
1
DNLJ_THEFI
B:
[1-584]
-----
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
-
L
E
-
P
T
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
A
---
L
--
G
R
KR
P
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
---
K
---
G
V--
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
--
L
-
G
---
L
E
-
E
-
S
GL
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
PVE
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
---
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
--
K
E
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
M
D
R
L
L
--
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
E
S
K
---------------------------------------------------------------------------------------------
55
HHSearch
67.90
42%
41
- C11 -
-
1V9P
1
DNLJ_THEFI
B:
[1-581]
-----
M
T
R
E
E
A
R
R
R
I
N
E
L
R
D
L
I
R
Y
H
N
Y
R
Y
Y
V
L
A
D
P
E
I
S
D
A
E
Y
D
R
L
L
R
E
L
K
E
L
E
E
R
F
P
E
F
K
S
P
D
S
P
T
E
Q
V
G
A
R
P
L
E
P
-
T
-
F
R
P
V
R
H
P
T
R
M
Y
S
L
D
N
A
F
T
Y
E
E
V
L
A
F
E
E
R
L
E
R
---
A
---
L
GR
K
R
--
P
F
L
Y
T
V
E
H
K
V
D
G
L
S
V
N
L
Y
Y
E
E
G
V
L
V
F
G
A
T
R
G
D
G
E
V
G
E
E
V
T
Q
N
L
L
T
I
P
T
I
P
R
R
L
---
K
G--
V
---
P
D
R
L
E
V
R
G
E
V
Y
M
P
I
E
A
F
L
R
L
N
E
E
L
E
E
R
G
E
K
V
F
K
N
P
R
N
A
A
A
G
S
L
R
Q
K
D
P
R
V
T
A
K
R
G
L
R
A
T
F
Y
A
L
G
-
L
G
-
L
---
E
E
S
G
-
L
--
K
S
Q
Y
E
L
L
L
W
L
K
E
K
G
F
---
P
V
E
H
G
Y
E
K
A
L
G
A
E
G
V
E
E
V
Y
R
R
F
L
A
Q
R
H
A
L
P
F
E
A
D
G
V
V
V
K
L
D
D
L
A
L
W
R
E
L
G
Y
T
A
R
A
P
R
F
A
L
A
Y
K
F
P
A
E
E
K
E
T
R
L
L
D
V
V
F
Q
V
G
R
T
G
R
V
T
P
V
G
V
L
E
P
V
F
I
E
G
S
E
V
S
R
V
T
L
H
N
E
S
Y
I
E
E
L
D
I
R
I
G
D
W
V
L
V
H
K
A
G
G
V
I
P
E
V
L
R
V
L
K
E
R
R
T
G
E
E
R
P
I
R
W
P
E
T
C
P
E
C
G
H
R
L
V
K
E
--
G
K
V
H
R
C
P
N
P
-
L
-
C
P
A
K
R
F
E
A
I
R
H
Y
A
S
R
K
A
M
D
I
E
G
L
G
E
K
L
I
E
R
L
L
E
K
G
L
V
R
D
V
A
D
L
Y
H
L
R
K
E
D
L
L
G
L
E
R
M
G
E
K
S
A
Q
N
L
L
R
Q
I
E
E
S
K
H
R
G
L
E
R
L
L
Y
A
L
G
L
P
G
V
G
E
V
L
A
R
N
L
A
R
R
F
G
T
--
M
D
R
LL
E
A
S
L
E
E
L
L
E
V
E
E
V
G
E
L
T
A
R
A
I
L
E
T
L
K
D
P
A
F
R
D
L
V
R
R
L
K
E
A
G
V
S
M
------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
65.00
57%
-49
- C11 -
-
4CC5
1
DNLJ_STAAU
A:
[5-309]
-----------
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
A
-
Q
A
-
S
-
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
---
Q
---
I
--
G
N
--
V
-
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
---
K
---
E
---
P
L
N
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
S
V
N
-
D
F
-
T
---
D
F
-
N
-
A
--
R
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
---
T
T
N
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
64.95
57%
-53
- C11 -
-
5FPO
3
DNLJ_STAAU
A:
[5-309]
-----------
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
-
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
A
-
Q
A
-
S
-
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
---
Q
---
I
--
G
N
--
V
-
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
---
K
---
E
---
P
L
N
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
-
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
S
V
N
-
D
F
-
T
---
D
F
-
N
-
A
--
R
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
---
T
T
N
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
63.72
56%
-69
- C11 -
-
4GLW
2
DNLJ_STRZP
B:
[3-304]
------------
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
V
-
L
D
-
G
-
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
---
E
---
V
--
A
H
--
P
T
-
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
---
P
---
E
---
E
L
D
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
Q
E
A
----
S
---
P
S
-
T
-
R
--
D
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
---
V
V
N
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
63.69
57%
-49
- C11 -
-
4CC6
1
DNLJ_STAAU
A:
[5-309]
-----------
S
S
R
V
N
E
L
H
D
L
L
N
Q
Y
S
Y
E
Y
Y
V
E
D
N
P
S
V
P
D
S
E
Y
D
K
L
L
H
E
L
I
K
I
E
E
E
H
P
E
Y
K
T
V
D
S
P
T
V
R
V
G
G
E
A
-
Q
A
-
S
-
F
N
K
V
N
H
D
T
P
M
L
S
L
G
N
A
F
N
E
D
D
L
R
K
F
D
Q
R
I
R
E
---
Q
---
I
--
G
N
--
V
-
E
Y
M
C
E
L
K
I
D
G
L
A
V
S
L
K
Y
V
D
G
Y
F
V
Q
G
L
T
R
G
D
G
T
T
G
E
D
I
T
E
N
L
K
T
I
H
A
I
P
L
K
M
---
K
---
E
---
P
L
N
V
E
V
R
G
E
A
Y
M
P
R
R
S
F
L
R
L
N
E
E
K
E
K
N
D
E
Q
L
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
S
K
L
T
A
K
R
K
L
S
V
F
I
Y
S
V
N
-
D
F
-
T
---
D
F
-
N
-
A
--
R
S
Q
S
E
A
L
D
E
L
D
K
L
G
F
---
T
T
N
K
N
R
A
R
V
N
N
I
D
G
V
L
E
Y
I
E
K
W
T
S
Q
R
E
S
L
P
Y
D
I
D
G
I
V
I
K
V
N
D
L
D
Q
Q
D
E
M
G
F
T
Q
K
S
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
63
HHSearch
62.65
56%
-67
* C11 *
-
4GLW
2
DNLJ_STRZP
B:
[2-304]
-----------
N
K
R
M
N
E
L
V
A
L
L
N
----------------------
Y
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
V
-
L
D
-
G
-
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
-------
E
--
V
A
--
H
P
T
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
---
P
---
E
---
E
L
D
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
Q
E
A
-
S
P
-
S
---
T
----
R
--
D
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
---
V
V
N
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
62.39
56%
-68
- C11 -
-
4GLW
1
DNLJ_STRZP
A:
[3-304]
------------
K
R
M
N
E
-----------------------------
R
E
L
V
E
L
E
T
A
Y
P
E
Q
V
L
A
D
S
P
T
H
R
V
G
G
K
V
-
L
D
-
G
-
F
E
K
Y
S
H
Q
Y
P
L
Y
S
L
Q
D
A
F
S
R
E
E
L
D
A
F
D
A
R
V
R
K
---
E
---
V
--
A
H
--
P
T
-
Y
I
C
E
L
K
I
D
G
L
S
I
S
L
T
Y
E
K
G
I
L
V
A
G
V
T
R
G
D
G
S
I
G
E
N
I
T
E
N
L
K
R
V
K
D
I
P
L
T
L
---
P
---
E
---
E
L
D
I
T
V
R
G
E
C
Y
M
P
R
A
S
F
D
Q
V
N
Q
A
R
Q
E
N
G
E
P
E
F
A
N
P
R
N
A
A
A
G
T
L
R
Q
L
D
T
A
V
V
A
K
R
N
L
A
T
F
L
Y
Q
E
A
----
S
---
P
S
-
T
-
R
--
D
S
Q
E
K
G
L
K
Y
L
E
Q
L
G
F
---
V
V
N
P
K
R
I
L
A
E
N
I
D
E
I
W
N
F
I
Q
E
V
G
Q
E
R
E
N
L
P
Y
D
I
D
G
V
V
I
K
V
N
D
L
A
S
Q
E
E
L
G
F
T
V
K
A
P
K
W
A
V
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
62
HHSearch
54.14
47%
3
- C11 -
-
3PN1
2
DNLJ_HAEIN
A:
[3-318]
---------
N
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
S
-
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
---
R
LIL
L
--
P
K
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
---
L
---
T
DNP
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
-
E
---
G
V
-
D
L
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
53.81
47%
14
- C11 -
-
3UQ8
2
DNLJ_HAEIN
A:
[2-321]
----------
I
Q
T
Q
L
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
S
-
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
---
R
LIL
L
--
P
A
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
---
L
---
T
DNP
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
-
E
---
G
V
-
D
L
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
53.36
46%
-2
- C11 -
-
4UFZ
2
DNLJ_HAEIN
A:
[9-317]
---------------
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
S
-
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
LI
L
---
L
--
P
K
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTD
N
---
P
---
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
E
G
---
V
D
-
L
-
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
52.71
46%
13
- C11 -
-
3UQ8
2
DNLJ_HAEIN
A:
[7-322]
---------------
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
S
-
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
A
R
I
E
D
R
LI
L
---
L
--
P
A
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTD
N
---
P
---
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
E
G
---
V
D
-
L
-
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
52.71
46%
0
- C11 -
-
4UCO
2
DNLJ_HAEIN
A:
[9-317]
---------------
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
S
-
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
LI
L
---
L
--
P
K
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTD
N
---
P
---
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
E
G
---
V
D
-
L
-
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
52.47
46%
2
- C11 -
-
3PN1
2
DNLJ_HAEIN
A:
[9-317]
---------------
D
N
L
R
K
T
L
R
Q
Y
E
Y
E
Y
H
V
L
D
N
P
S
V
P
D
S
E
Y
D
R
L
F
H
Q
L
K
A
L
E
L
E
H
P
E
F
L
T
S
D
S
P
T
Q
R
V
G
A
K
P
-
L
S
-
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
LI
L
---
L
--
P
K
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTD
N
---
P
---
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
E
G
---
V
D
-
L
-
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
G
F
Y
R
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
47.29
45%
2
- C11 -
-
3BAC
1
DNLJ_HAEIN
A:
[6-260]
-----------------------------------------------------------------------------
G
-
F
S
Q
I
R
H
E
I
P
M
L
S
L
D
N
A
F
S
D
A
E
F
N
A
F
V
K
R
I
E
D
R
LI
L
---
L
--
P
K
--
P
L
T
F
C
C
E
P
K
L
D
G
L
A
V
S
I
L
Y
V
N
G
E
L
T
Q
A
A
T
R
G
D
G
T
T
G
E
D
I
T
A
N
I
R
T
I
R
N
V
P
L
Q
L
LTD
N
---
P
---
P
A
R
L
E
V
R
G
E
V
F
M
P
H
A
G
F
E
R
L
N
K
Y
A
L
E
H
N
E
K
T
F
A
N
P
R
N
A
A
A
G
S
L
R
Q
L
D
P
N
I
T
S
K
R
P
L
V
L
N
A
Y
G
I
G
-
I
A
E
G
---
V
G
-
L
-
P
--
T
T
H
Y
A
R
L
Q
W
L
K
S
I
G
I
---
P
V
N
P
E
I
R
L
C
N
G
A
D
E
V
L
D
F
Y
Q
D
I
Q
N
K
R
S
S
L
G
Y
D
I
D
G
T
V
L
K
I
N
D
I
A
L
Q
N
E
L
G
F
I
S
K
A
P
R
W
A
I
A
Y
K
F
P
A
Q
E
E
L
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------