@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3XZQ9: (2018-01-16 )
MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEAQMAAEDAMNNQTK
Atome Classification :
(58 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.....-----..150...-------------...-------------------------------------------------------------------------.160.......170--------------------------------------------------------------------------------------------------------------------------------------------------------------------------........180.......190.......200......-.210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310....-.-..320.......330.......340.......350.......360.......370.......380.......390.......400-.---........410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510......----------.520---------........530.......540....--...550-.--------------......---------..--560-------....--...-570.-......580.......590.......600..--.....610.......---620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730-------------.........740.......750.......760.......770.......780.......790.......800.......810.......820.......830.......840-.-------....--------.-----..850.----......860.......870...----....880.--..----..----..890.......900.......910.......920.......930.......940.......950.-.-..--------...960.......970.......980...--------....990.....-..1000..--...------------....1010......1020......1030......1040......1050......1060......1070......1080......1090......1100......1110......1120......1130......1140......1150......1160......1170......1180......1190......1200......1210......1220.
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MKWRE
P
L
L
I
D
VNKF
E
S
M
Q
IGLA
S
P
E
K
IRSWSYGEVKKPETINYRTLKPEREG
L
F
C
E
R
IFGPTKDWECACGK
Y
K
R
I
R
Y
K
G
I
V
CDRCG
V
E
V
T
R
S
K
V
R
R
E
RMG
H
I
E
LAAPVS
H
I
W
Y
FKGIPSRM
G
L
V
LDM
S
P
R
A
L
E
E
I
I
Y
F
A
S
Y
V
V
IEPG-----NT
N
L
E
K
K
Q
-------------
L
L
T
-------------------------------------------------------------------------
E
R
E
Y
R
E
K
R
E
Q
Y
G
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
Q
A
A
M
G
A
E
A
I
K
Q
L
L
DNVDLD
A
E
A
A
E
L
K
E
E
L
K
S
AQG
Q
-
K
R
T
R
A
I
R
R
L
D
I
L
E
A
F
RASGNQP
S
W
M
V
M
D
VIPVIPPDLR
P
M
V
Q
LEGGRFATS
D
L
N
D
L
Y
R
R
V
INR
N
N
R
L
K
R
L
L
DLNAP
G
I
I
VQ
N
E
K
R
M
L
Q
E
A
V
D
A
L
IDNGRRGRPVTGPG-N-R
P
L
K
S
L
S
H
M
L
KGKQG
R
F
R
Q
N
L
LGKRVDYSG
R
S
V
I
V
VG
P
F
L
K
M
Y
QCGL
P
K
E
M
A
I
E
L
F
K
P
F
V
M
R
E
L
V
Q
R
E
L
A
S
N
I
K
N
A
K
R
K
I
E
R
Q
---
E
---
D
E
V
W
D
V
L
E
D
V
I
K
EHPVLLNRAP
T
L
H
R
L
G
I
Q
A
F
E
P
VLVQG
R
A
I
R
L
H
P
L
V
C
EAYNADFDGD
Q
M
A
V
H
VPLN
E
E
A
Q
A
E
A
R
M
L
M
L
A
A
Q
N
ILNPKDGKPVVTPSQ
D
M
V
L
G
N
Y
Y
L
T
M
EEEGREG----------E
G
M
----------
V
F
RDQN
E
A
V
I
A
WRN
G
Y
V
H
L
H
S
RIGV--NPNS---L--------------GEKP
F
T
---------
E
W
--
Q
K
E
-------
R
T
M
I
--
T
T
V
-
G
K
I
I
-
F
N
EIMPPEFPYLNEPTD
F
N
L
T
VQTPD
K
Y
F
VE--AGTDIPAHIKEQ
E
L
V
---
L
P
F
K
KK
N
L
G
N
I
I
A
E
V
F
K
R
FKVT
E
T
S
K
M
L
D
R
M
K
D
LGYKHSTHA
G
I
T
V
G
I
A
D
I
S
V
L
N
E
K
Q
E
I
I
E
N
A
H
K
Q
V
E
T
I
T
K
Q
F
R
R
GLIT
D
D
E
R
Y
E
R
V
I
A
V
W
N
A
A
K
D
S
I
Q
Q
K
L
M
E
G
LEAK---------------N
P
I
F
M
MSDSGARGN
I
S
N
F
T
Q
L
A
GMRGLMAAPNG
R
I
M
E
L
P
I
I
S
N
F
R
E
G
L
S
V
L
E
M
F
I
S
THGARKGMTDTALKTAD
S
G
Y
L
T
R
R
L
V
D
V
A
Q
D
V
I
I
REEDCGTDRG
L
E
I
Q
A
IRE
G
N
E
--
I
-------
I
E
S
L
--------
E
-----
D
R
L
V
G
R
----
Y
T
R
K
EVRHPET
N
E
L
I
I
AG
N
Q
L
I
----
S
E
D
I
A
K
Q
I
--
V
D
----AG----V
E
T
V
T
I
R
S
V
F
TCNTKH
G
V
C
K
H
C
YGRNLATGSDV
E
V
G
E
A
V
G
T
I
A
A
Q
SIGEPGT
Q
L
T
M
R
T
FHTGGVA
G
-
D
-
D
I
--------
T
Q
G
L
P
R
V
Q
E
I
F
E
ARNPKG
Q
A
V
I
T
EVTG
D
V
--------
I
DISEDPATR
T
K
-
E
V
T
---
I
K--GKT------------D
T
R
T
Y
T
VP
Y
T
A
R
M
K
VAEGDMIHRGAPLTEGSI
D
P
K
Q
L
L
Q
V
R
D
V
L
S
V
E
N
Y
L
L
R
E
V
Q
R
V
Y
R
MQGVEI
G
D
K
H
I
E
V
M
V
R
Q
M
L
R
KVRVMDPGDTDILPG
T
L
LDIADFKDQNY
N
T
L
VSGGVPATSR
P
V
L
L
G
I
T
K
ASLETNSFL
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
AIRGKKDPLLGLKEN
V
I
I
G
K
I
IPAGTG
M
Q
R
YRDM
E
P
K
EVGVASEN
V
Y
S
I
S
D
I
E
A
Q
M
A
A
E
D
AMNNQTK
104
Fugue
94.08
51%
0
- C- -
-
1IW7
-
RPOC_THET8
D:
[2-1505]
----------
K
K
E
V
R
K
V
R
I
A
L
A
S
P
E
K
I
R
S
W
S
Y
G
E
V
E
K
P
E
T
I
N
Y
R
T
L
K
P
E
R
D
G
L
F
D
E
R
I
F
G
P
I
K
D
Y
E
C
A
C
G
K
Y
K
R
Q
R
F
E
G
K
V
C
E
R
C
G
V
E
V
T
K
S
I
V
R
R
Y
R
M
G
H
I
E
L
A
T
P
A
A
H
I
W
F
V
K
D
V
P
S
K
I
G
T
L
L
D
L
S
A
T
E
L
E
Q
V
L
Y
F
S
K
Y
I
V
L
D
P
K
GAILN
G
V
P
V
E
K
R
Q
-------------
L
L
T
-------------------------------------------------------------------------
D
E
E
Y
R
E
L
R
Y
G
K
Q
E
TYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESY
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
-
S
D
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
---
R
DIK
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
Q
P
V
L
V
E
G
Q
S
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
V
P
L
S
S
F
A
Q
A
E
A
R
I
Q
M
L
S
A
H
N
L
L
S
P
A
S
G
E
P
L
A
K
P
S
R
D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
--
A
G
R
E
TSV
G
--------------
R
L
K
Y
V
F
---------
A
N
--
P
D
E
-------
A
L
L
A
--
V
A
H
-
G
I
V
D
-
L
Q
D
V
V
--
T
V
R
Y
M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
V
A
E
--
A
V
E
D
E
K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
E
K
N
S
L
K
D
L
V
Y
Q
A
F
L
R
L
G
M
E
K
T
A
R
L
L
D
A
L
K
Y
Y
G
F
T
F
S
T
T
S
G
I
T
I
G
I
D
D
A
V
I
P
E
E
K
K
Q
Y
L
E
E
A
D
R
K
L
L
Q
I
E
Q
A
Y
E
M
G
F
L
T
D
R
E
R
Y
D
Q
I
L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
G
L
R
G
L
M
Q
K
P
S
G
E
T
F
E
V
P
V
R
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
S
S
H
G
A
R
K
G
G
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
K
L
V
D
V
T
H
E
I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
P
L
F
Q
P
D
E
V
--
T
RSLRLRK
R
A
D
I
--------
E
-----
A
G
L
Y
G
R
----
V
L
A
R
E
V
E
V
L
G
V
---
R
L
E
E
G
R
Y
L
SMDD
V
H
L
L
I
K
A
A
--
E
A
----
G
E
----
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
M
R
T
F
H
T
G
G
V
A
G
-
A
A
D
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-----------
V
V
R
I
E
E
T
E
E
K
L
-
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
S
D
F
V
R
F
T
Q
V
V
------------
D
Q
K
T
L
K
A
I
E
E
A
R
K
E
A
V
E
A
27
PsiBlast_CBE
80.28
52%
0
- C- -
-
4YLN
1
RPOC_ECOLI
J:
[16-1031]
------------
E
F
D
A
I
K
I
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-----
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-------------
I
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T
-------------------------------------------------------------------------
E
E
Q
Y
L
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D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
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N
A
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----------
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M
----------
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P
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--
R
-------------------------
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T
---------
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--
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K
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ANGELVA
K
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KD
T
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-
G
R
A
I
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L
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V
P
K
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Y
-----------------------------
S
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N
D
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L
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T
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TVINRDGQEEKQVSF
N
S
I
Y
M
M
A
D
S
G
A
R
G
S
A
A
Q
I
R
Q
L
A
G
M
R
G
L
M
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I
T
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V
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--
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-------
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L
--------
R
-----
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R
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----
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----
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L
L
--
E
E
----
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S
----
V
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A
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V
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V
V
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C
D
T
D
F
G
V
C
A
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R
G
H
I
I
N
K
G
E
A
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V
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E
P
G
T
Q
L
T
M
R
T
F
H
I
G
G
A
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-
R
-
A
A
AESSIQVK
N
K
G
S
I
K
L
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N
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V
N
S
S
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K
L
V
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T
S
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N
T
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L
--------
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L
I
--
D
E
F
G
R
T
K
-
E
---------------------------
S
Y
K
V
P
Y
G
A
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L
A
K
G
D
G
E
Q
V
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--
T
V
A
N
W
D
P
H
T
M
P
V
I
T
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
80.28
52%
0
- C- -
-
4YLO
1
RPOC_ECOLI
J:
[16-1031]
------------
E
F
D
A
I
K
I
A
L
A
S
P
D
M
I
R
S
W
S
F
G
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N
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V
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D
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L
C
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T
A
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G
L
L
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M
P
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S
Y
V
V
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G
G
-----
M
T
N
L
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Q
Q
-------------
I
L
T
-------------------------------------------------------------------------
E
E
Q
Y
L
D
A
L
E
E
F
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
D
A
K
M
G
A
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A
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Q
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L
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S
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L
R
E
E
L
N
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T
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K
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I
K
L
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K
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F
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K
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---
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T
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C
V
N
A
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----------
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G
M
----------
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G
P
K
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L
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V
--
R
-------------------------
I
T
---------
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Y
--
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ANGELVA
K
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KD
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-
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R
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L
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M
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V
P
K
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Y
-----------------------------
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D
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TVINRDGQEEKQVSF
N
S
I
Y
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M
A
D
S
G
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A
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I
R
Q
L
A
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M
R
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I
T
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T
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V
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--
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-------
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L
--------
R
-----
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R
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----
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----
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L
L
--
E
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----
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S
----
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R
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H
I
I
N
K
G
E
A
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V
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A
A
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S
I
G
E
P
G
T
Q
L
T
M
R
T
F
H
I
G
G
A
A
S
-
R
-
A
A
AESSIQVK
N
K
G
S
I
K
L
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N
V
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S
V
V
N
S
S
G
K
L
V
I
T
S
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N
T
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L
--------
K
L
I
--
D
E
F
G
R
T
K
-
E
---------------------------
S
Y
K
V
P
Y
G
A
V
L
A
K
G
D
G
E
Q
V
A
G
G
E
--
T
V
A
N
W
D
P
H
T
M
P
V
I
T
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
80.28
52%
0
- C- -
-
4YLP
1
RPOC_ECOLI
J:
[16-1031]
------------
E
F
D
A
I
K
I
A
L
A
S
P
D
M
I
R
S
W
S
F
G
E
V
K
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N
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R
T
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V
K
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R
I
G
L
L
L
D
M
P
L
R
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R
V
L
Y
F
E
S
Y
V
V
I
E
G
G
-----
M
T
N
L
E
R
Q
Q
-------------
I
L
T
-------------------------------------------------------------------------
E
E
Q
Y
L
D
A
L
E
E
F
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
D
A
K
M
G
A
E
A
I
Q
A
L
L
K
S
M
D
L
E
Q
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C
E
Q
L
R
E
E
L
N
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T
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K
K
L
T
K
R
I
K
L
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T
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L
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----------
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--
R
-------------------------
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---------
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ANGELVA
K
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KD
T
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K
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-----------------------------
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A
N
D
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A
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L
Q
T
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TVINRDGQEEKQVSF
N
S
I
Y
M
M
A
D
S
G
A
R
G
S
A
A
Q
I
R
Q
L
A
G
M
R
G
L
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--
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-------
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--------
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-----
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----
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----
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--
E
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----
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----
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C
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K
G
E
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T
Q
L
T
M
R
T
F
H
I
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-
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A
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AESSIQVK
N
K
G
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K
L
V
I
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N
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--------
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L
I
--
D
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F
G
R
T
K
-
E
---------------------------
S
Y
K
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P
Y
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A
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A
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G
E
Q
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E
--
T
V
A
N
W
D
P
H
T
M
P
V
I
T
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
80.28
52%
0
- C- -
-
4YLP
1
RPOC_ECOLI
D:
[16-1031]
------------
E
F
D
A
I
K
I
A
L
A
S
P
D
M
I
R
S
W
S
F
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R
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Y
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-----
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Q
-------------
I
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T
-------------------------------------------------------------------------
E
E
Q
Y
L
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A
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F
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D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
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---
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----------
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--
R
-------------------------
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---------
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ANGELVA
K
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KD
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-
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-----------------------------
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TVINRDGQEEKQVSF
N
S
I
Y
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A
D
S
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R
Q
L
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--------
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-----
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----
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--
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----
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----
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K
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E
P
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T
Q
L
T
M
R
T
F
H
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G
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A
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-
R
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A
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AESSIQVK
N
K
G
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K
L
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--------
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--
D
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F
G
R
T
K
-
E
---------------------------
S
Y
K
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A
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A
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D
G
E
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E
--
T
V
A
N
W
D
P
H
T
M
P
V
I
T
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
80.28
52%
0
- C- -
-
4YLO
1
RPOC_ECOLI
D:
[16-1031]
------------
E
F
D
A
I
K
I
A
L
A
S
P
D
M
I
R
S
W
S
F
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Y
V
V
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G
-----
M
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N
L
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Q
Q
-------------
I
L
T
-------------------------------------------------------------------------
E
E
Q
Y
L
D
A
L
E
E
F
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
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A
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A
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---
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--
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-------------------------
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---------
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ANGELVA
K
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KD
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P
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-----------------------------
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TVINRDGQEEKQVSF
N
S
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A
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Q
L
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--------
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-----
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----
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H
I
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N
K
G
E
A
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V
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A
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I
G
E
P
G
T
Q
L
T
M
R
T
F
H
I
G
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A
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-
R
-
A
A
AESSIQVK
N
K
G
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V
N
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K
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--------
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--
D
E
F
G
R
T
K
-
E
---------------------------
S
Y
K
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A
V
L
A
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D
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E
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E
--
T
V
A
N
W
D
P
H
T
M
P
V
I
T
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
80.28
52%
0
- C- -
-
4YLN
1
RPOC_ECOLI
D:
[16-1031]
------------
E
F
D
A
I
K
I
A
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A
S
P
D
M
I
R
S
W
S
F
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R
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Y
V
V
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G
G
-----
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Q
Q
-------------
I
L
T
-------------------------------------------------------------------------
E
E
Q
Y
L
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A
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F
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D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
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A
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A
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----------
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-------------------------
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ANGELVA
K
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-----------------------------
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TVINRDGQEEKQVSF
N
S
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S
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--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
PsiBlast_CBE
77.88
49%
0
- C- -
-
2PPB
4
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
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LRKRA
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------------
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----------------------------------------
84
PsiBlast_CBE
77.88
49%
0
- C- -
-
2PPB
6
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
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A
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P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
17
PsiBlast_PDB
72.19
52%
19
- C5 -
-
5UHB
2
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
E
L
F
K
P
F
V
M
K
R
L
V
D
L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
E
E
V
I
A
E
H
P
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
E
P
M
L
V
E
G
K
A
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
L
P
L
S
A
E
A
Q
A
E
A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
PASGDHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
R
S
G
V
T
V
S
M
A
D
V
L
V
P
P
R
K
K
E
I
L
D
H
Y
E
E
R
A
D
K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
T
N
P
K
G
E
F
I
P
R
P
V
K
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
D
PYI
E
T
S
A
Y
A
R
T
L
G
T
D
A
V
D
E
A
G
N
V
I
V
ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
R
L
E
D
G
ER
F
Y
K
I
T
I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
E
V
G
Q
Q
L
M
E
G
S
A
D
P
H
E
V
L
R
V
Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
E
N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
29
PsiBlast_CBE
71.79
52%
19
- C5 -
-
5UHF
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
E
L
F
K
P
F
V
M
K
R
L
V
D
L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
E
E
V
I
A
E
H
P
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
E
P
M
L
V
E
G
K
A
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
L
P
L
S
A
E
A
Q
A
E
A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
R
S
G
V
T
V
S
M
A
D
V
L
V
P
P
R
K
K
E
I
L
D
H
Y
E
E
R
A
D
K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
T
N
P
K
G
E
F
I
P
R
P
V
K
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
D
PYI
E
T
S
A
Y
A
R
T
L
G
T
D
A
V
D
E
A
G
N
V
I
V
ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
R
L
EDGER
F
Y
K
I
T
I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
E
V
G
Q
Q
L
M
E
G
S
A
D
P
H
E
V
L
R
V
Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
E
N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
12
PsiBlast_PDB
71.70
52%
20
- C5 -
-
5UH5
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
E
L
F
K
P
F
V
M
K
R
L
V
D
L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
E
E
V
I
A
E
H
P
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
E
P
M
L
V
E
G
K
A
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
L
P
L
S
A
E
A
Q
A
E
A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
R
S
G
V
T
V
S
M
A
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V
L
V
P
P
R
K
K
E
I
L
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H
Y
E
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R
A
D
K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
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N
P
K
G
E
F
I
P
R
P
V
K
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S
F
R
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L
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V
L
E
Y
F
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N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
DPYI
E
T
S
A
Y
A
R
T
L
G
T
D
A
V
D
E
A
G
N
V
I
V
ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
R
L
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F
Y
K
I
T
I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
E
V
G
Q
Q
L
M
E
G
S
A
D
P
H
E
V
L
R
V
Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
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N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
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G
L
K
E
N
V
I
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G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
14
PsiBlast_PDB
71.69
52%
18
- C5 -
-
5UH8
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
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Q
S
G
N
S
P
M
G
M
V
L
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V
P
V
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P
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L
R
P
M
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Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
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K
R
M
L
Q
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S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
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L
F
K
P
F
V
M
K
R
L
V
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L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
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V
L
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V
I
A
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L
L
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L
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L
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L
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A
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R
I
L
M
L
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S
N
N
I
L
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P
A
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G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
PASGDHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
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V
D
K
L
K
D
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G
F
Y
W
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G
V
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L
V
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P
R
K
K
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L
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Q
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Q
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A
L
N
H
D
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R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
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M
K
G
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V
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N
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K
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E
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R
P
V
K
S
S
F
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L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
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A
L
R
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A
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Y
L
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R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
DPYI
E
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S
A
Y
A
R
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L
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T
D
A
V
D
E
A
G
N
V
I
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ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
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A
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K
L
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D
I
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E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
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R
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F
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I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
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V
G
Q
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S
A
D
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E
V
L
R
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G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
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D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
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N
R
R
V
V
A
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G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
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F
Q
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T
T
R
V
L
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D
A
A
I
N
C
R
S
D
K
L
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L
K
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N
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K
L
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A
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T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
15
PsiBlast_PDB
71.64
52%
19
- C5 -
-
5UH9
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
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N
F
D
I
D
A
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A
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L
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V
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R
N
G
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G
Q
-
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V
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G
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M
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M
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R
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N
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L
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R
L
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A
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N
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R
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G
R
P
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T
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P
G
-
N
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R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
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D
Y
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G
R
S
V
I
V
V
G
P
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L
K
L
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Q
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L
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K
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L
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R
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L
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A
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R
M
V
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Q
---
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---
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Q
V
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L
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L
L
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L
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A
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A
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L
M
L
S
S
N
N
I
L
S
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G
R
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L
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P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
PASGDHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
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K
L
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R
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A
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A
L
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E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
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F
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L
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L
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G
A
R
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A
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Q
D
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G
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V
V
-------
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--
L
-------
A
E
R
A
--------
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-----
D
G
T
L
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D
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E
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A
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A
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L
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A
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D
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A
G
N
V
I
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G
Q
D
L
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D
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--
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D
A
L
L
A
A
G
----
I
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Q
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L
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C
A
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A
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A
V
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A
A
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G
E
P
G
T
Q
L
-------------------------
T
G
G
L
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L
F
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A
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K
A
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F
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G
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V
Y
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K
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--
K
R
Q
------------
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L
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E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
E
N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
20
PsiBlast_PDB
71.59
52%
17
- C5 -
-
5UHE
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
E
L
F
K
P
F
V
M
K
R
L
V
D
L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
E
E
V
I
A
E
H
P
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
E
P
M
L
V
E
G
K
A
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
L
P
L
S
A
E
A
Q
A
E
A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
R
S
G
V
T
V
S
M
A
D
V
L
V
P
P
R
K
K
E
I
L
D
H
Y
E
E
R
A
D
K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
T
N
P
K
G
E
F
I
P
R
P
V
K
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
D
PYI
E
T
S
A
Y
A
R
T
L
G
T
D
A
V
D
E
A
G
N
V
I
V
ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
R
L
EDGER
F
Y
K
I
T
I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
E
V
G
Q
Q
L
M
E
G
S
A
D
P
H
E
V
L
R
V
Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
E
N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
19
PsiBlast_PDB
71.45
52%
19
- C5 -
-
5UHD
2
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
E
L
F
K
P
F
V
M
K
R
L
V
D
L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
E
E
V
I
A
E
H
P
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
E
P
M
L
V
E
G
K
A
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
L
P
L
S
A
E
A
Q
A
E
A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
R
S
G
V
T
V
S
M
A
D
V
L
V
P
P
R
K
K
E
I
L
D
H
Y
E
E
R
A
D
K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
T
N
P
K
G
E
F
I
P
R
P
V
K
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
D
PYI
E
T
S
A
Y
A
R
T
L
G
T
D
A
V
D
E
A
G
N
V
I
V
ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
R
L
E
D
G
ER
F
Y
K
I
T
I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
E
V
G
Q
Q
L
M
E
G
S
A
D
P
H
E
V
L
R
V
Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
E
N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
28
PsiBlast_CBE
71.43
52%
18
- C5 -
-
5UHG
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
V
I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
E
L
F
K
P
F
V
M
K
R
L
V
D
L
N
H
A
Q
N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
E
E
V
I
A
E
H
P
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
E
P
M
L
V
E
G
K
A
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
L
P
L
S
A
E
A
Q
A
E
A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
PASGDHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
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S
G
V
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V
S
M
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V
L
V
P
P
R
K
K
E
I
L
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R
A
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K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
T
N
P
K
G
E
F
I
P
R
P
V
K
S
S
F
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E
G
L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
S
Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
DPYI
E
T
S
A
Y
A
R
T
L
G
T
D
A
V
D
E
A
G
N
V
I
V
ER--
G
Q
D
L
G
D
P
E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
R
L
EDGER
F
Y
K
I
T
I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
E
V
G
Q
Q
L
M
E
G
S
A
D
P
H
E
V
L
R
V
Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
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N
R
R
V
V
A
E
G
G
E
P
A
A
G
R
P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
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F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
13
PsiBlast_PDB
71.37
52%
20
- C5 -
-
5UH6
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
E
N
F
D
I
D
A
E
A
E
S
L
R
D
V
I
R
N
G
K
G
Q
-
K
K
L
R
A
L
K
R
L
K
V
V
A
A
F
Q
Q
S
G
N
S
P
M
G
M
V
L
D
A
V
P
V
I
P
P
E
L
R
P
M
V
Q
L
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
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I
N
R
N
N
R
L
K
R
L
I
D
L
G
A
P
E
I
I
V
N
N
E
K
R
M
L
Q
E
S
V
D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
L
M
A
L
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L
F
K
P
F
V
M
K
R
L
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D
L
N
H
A
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N
I
K
S
A
K
R
M
V
E
R
Q
---
R
---
P
Q
V
W
D
V
L
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V
I
A
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P
V
L
L
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L
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L
P
L
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A
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L
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S
N
N
I
L
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A
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G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
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K
L
K
D
A
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F
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G
V
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V
L
V
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P
R
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L
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A
L
N
H
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N
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A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
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P
K
G
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R
P
V
K
S
S
F
R
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L
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V
L
E
Y
F
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N
T
H
G
A
R
K
G
L
A
D
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A
L
R
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A
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Y
L
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R
L
V
D
V
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Q
D
V
I
V
R
E
H
D
C
Q
T
E
R
G
I
V
V
-------
E
--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
D
PYI
E
T
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A
Y
A
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A
V
D
E
A
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N
V
I
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ER--
G
Q
D
L
G
D
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E
--
I
D
A
L
L
A
A
G
----
I
T
Q
V
K
V
R
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V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
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A
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K
L
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D
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G
E
A
V
G
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V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
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A
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V
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F
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I
V
P
D
D
G
G
E
-
E
V
V
Y
D
K
I
S
--
K
R
Q
------------
R
L
R
V
F
K
H
E
D
G
S
E
R
V
L
S
D
G
D
H
V
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G
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A
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P
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L
R
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Q
G
P
R
E
V
Q
I
H
L
V
R
E
V
Q
E
V
Y
R
A
Q
G
V
S
I
H
D
K
H
I
E
V
I
V
R
Q
M
L
R
R
V
T
I
I
D
S
G
S
T
E
F
L
P
G
S
L
I
D
R
A
E
F
E
A
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N
R
R
V
V
A
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G
G
E
P
A
A
G
R
P
V
L
M
G
I
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K
A
S
L
A
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D
S
W
L
S
A
A
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F
Q
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T
T
R
V
L
T
D
A
A
I
N
C
R
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D
K
L
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G
L
K
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N
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K
L
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A
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T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
16
PsiBlast_PDB
71.18
52%
19
- C5 -
-
5UHA
2
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
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N
F
D
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D
A
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A
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L
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D
V
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N
G
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-
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A
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M
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M
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V
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A
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L
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Y
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R
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R
N
N
R
L
K
R
L
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A
P
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N
N
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K
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L
Q
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D
A
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N
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R
R
G
R
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T
G
P
G
-
N
-
R
P
L
K
S
L
S
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L
L
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G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
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D
Y
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G
R
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V
I
V
V
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L
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L
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C
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L
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L
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A
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M
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Q
---
R
---
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Q
V
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L
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M
L
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S
N
N
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L
A
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P
R
L
D
M
V
T
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L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
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V
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E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
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L
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L
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A
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A
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L
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D
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D
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G
I
V
V
-------
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--
L
-------
A
E
R
A
--------
P
-----
D
G
T
L
I
R
DPYI
E
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S
A
Y
A
R
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L
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D
A
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D
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A
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N
V
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ER--
G
Q
D
L
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--
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D
A
L
L
A
A
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----
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Q
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C
A
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A
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A
V
G
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A
A
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G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
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L
F
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A
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K
A
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F
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D
D
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G
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V
Y
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K
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--
K
R
Q
------------
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P
V
L
M
G
I
T
K
A
S
L
A
T
D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
I
G
K
L
I
P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
10
PsiBlast_PDB
71.14
52%
-0
- C5 -
-
5IPN
-
RPOC_ECOLI
D:
[16-1031]
------------
E
F
D
A
I
K
I
A
L
A
S
P
D
M
I
R
S
W
S
F
G
E
V
K
K
P
E
T
I
N
Y
R
T
F
K
P
E
R
D
G
L
F
C
A
R
I
F
G
P
V
K
D
Y
E
C
L
C
G
K
Y
K
R
L
K
H
R
G
V
I
C
E
K
C
G
V
E
V
T
Q
T
K
V
R
R
E
R
M
G
H
I
E
L
A
S
P
T
A
H
I
W
F
L
K
S
L
P
S
R
I
G
L
L
L
D
M
P
L
R
D
I
E
R
V
L
Y
F
E
S
Y
V
V
I
E
G
G
-----
M
T
N
L
E
R
Q
Q
-------------
I
L
T
-------------------------------------------------------------------------
E
E
Q
Y
L
D
A
L
E
E
F
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
F
D
A
K
M
G
A
E
A
I
Q
A
L
L
K
S
M
D
L
E
Q
E
C
E
Q
L
R
E
E
L
N
E
T
N
S
E
T
K
R
K
K
L
T
K
R
I
K
L
L
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A
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V
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P
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M
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L
T
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L
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L
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P
D
L
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L
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P
L
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G
G
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A
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N
D
L
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L
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L
L
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L
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N
-
K
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R
P
L
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L
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L
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I
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P
Y
L
R
L
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C
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M
A
L
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L
F
K
P
F
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K
L
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L
R
G
L
A
T
T
I
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A
A
K
K
M
V
E
R
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---
E
---
A
V
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L
D
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V
I
R
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H
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V
L
L
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L
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I
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V
L
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A
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L
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L
V
C
A
A
Y
N
A
D
F
D
G
D
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M
A
V
H
V
P
L
T
L
E
A
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L
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A
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A
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M
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T
N
N
I
L
S
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A
N
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E
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I
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P
S
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D
V
V
L
G
L
Y
Y
M
T
R
D
C
V
N
A
K
G
----------
E
G
M
----------
V
L
T
G
P
K
E
A
E
R
L
Y
R
S
G
L
A
S
L
H
A
R
V
K
V
--
R
-------------------------
I
T
---------
E
Y
--
E
K
D
ANGELVA
K
T
S
L
KD
T
T
V
-
G
R
A
I
-
L
W
M
I
V
P
K
G
L
P
Y
-----------------------------
S
I
V
N
Q
A
L
-------
G
K
K
A
I
S
K
M
L
N
T
C
Y
R
I
L
G
L
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P
T
V
I
F
A
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A
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K
H
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A
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L
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I
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A
A
A
N
D
R
V
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K
A
M
M
D
N
L
Q
T
E
TVINRDGQEEKQVSF
N
S
I
Y
M
M
A
D
S
G
A
R
G
S
A
A
Q
I
R
Q
L
A
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M
R
G
L
M
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P
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T
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L
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L
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L
T
R
R
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M
T
P
V
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--
V
-------
K
E
P
L
--------
R
-----
D
R
V
L
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R
----
V
T
A
E
D
V
L
K
P
G
T
A
D
I
L
V
P
R
N
T
L
L
----
H
E
Q
W
C
D
L
L
--
E
E
----
N
S
----
V
D
A
V
K
V
R
S
V
V
S
C
D
T
D
F
G
V
C
A
H
C
Y
G
R
D
L
A
R
G
H
I
I
N
K
G
E
A
I
G
V
I
A
A
Q
S
I
G
E
P
G
T
Q
L
T
M
R
T
F
H
I
G
G
A
A
S
-
R
-
A
A
AESSIQVK
N
K
G
S
I
K
L
S
N
V
K
S
V
V
N
S
S
G
K
L
V
I
T
S
R
N
T
E
L
--------
K
L
I
--
D
E
F
G
R
T
K
-
E
---------------------------
S
Y
K
V
P
Y
G
A
V
L
A
K
G
D
G
E
Q
V
A
G
G
E
--
T
V
A
N
W
D
P
H
T
M
P
V
I
T
E
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
71.13
52%
20
- C5 -
-
5UHC
3
RPOC_MYCTU
D:
[227-1281]
---------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
L
A
P
K
Q
-------------
L
I
V
D------------------------------------------------------------------------
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
G
A
M
G
A
E
S
I
Q
K
L
I
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N
F
D
I
D
A
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A
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V
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R
N
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-
K
K
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A
L
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R
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V
V
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S
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M
G
M
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L
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L
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L
D
G
G
R
F
A
T
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D
L
N
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L
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R
R
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I
N
R
N
N
R
L
K
R
L
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L
G
A
P
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V
N
N
E
K
R
M
L
Q
E
S
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D
A
L
F
D
N
G
R
R
G
R
P
V
T
G
P
G
-
N
-
R
P
L
K
S
L
S
D
L
L
K
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
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C
G
L
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K
L
M
A
L
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L
F
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F
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M
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R
L
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L
N
H
A
Q
N
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A
K
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M
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---
R
---
P
Q
V
W
D
V
L
E
E
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I
A
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P
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L
L
N
R
A
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L
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L
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A
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L
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L
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C
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A
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A
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F
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A
V
H
L
P
L
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A
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A
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A
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A
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I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
----------
E
Y
Q
P
A
S
G
DHPETG
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
RPP
V
E
I
E
A
E
L
FGHS
G
W
Q
P
G
D
---------
A
W
--
M
A
E
-------------
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
K
--------------------------------------
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
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T
V
D
K
L
K
D
A
G
F
Y
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L
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P
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K
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N
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E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
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M
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F
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L
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L
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A
R
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G
L
A
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R
L
V
D
V
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D
V
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R
G
I
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V
-------
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--
L
-------
A
E
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A
--------
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-----
D
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L
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N
V
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G
Q
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L
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--
I
D
A
L
L
A
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----
I
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Q
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V
L
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A
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P
G
T
Q
L
-------------------------
T
G
G
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R
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K
A
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F
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D
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G
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-
E
V
V
Y
D
K
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--
K
R
Q
------------
R
L
R
V
F
K
H
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D
G
S
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L
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D
G
D
H
V
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L
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V
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P
R
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I
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L
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A
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I
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H
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L
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T
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A
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A
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N
R
R
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V
A
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G
G
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A
A
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P
V
L
M
G
I
T
K
A
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L
A
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D
S
W
L
S
A
A
S
F
Q
E
T
T
R
V
L
T
D
A
A
I
N
C
R
S
D
K
L
N
G
L
K
E
N
V
I
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G
K
L
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P
A
G
T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
117
HHSearch
70.84
57%
20
- C5 -
-
5UH6
3
RPOC_MYCTU
D:
[3-1281]
---------
D
V
N
F
F
D
E
L
R
I
G
L
A
T
A
E
D
I
R
Q
W
S
Y
G
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P
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L
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A
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V
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D
-----
E
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M
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N
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L
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A
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A
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L
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L
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A
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T
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LAPKQLIVD
E
N
L
Y
R
E
L
V
D
R
Y
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
F
T
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A
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G
A
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I
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K
L
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N
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D
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N
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-
N
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L
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L
L
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V
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L
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L
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L
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N
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A
K
R
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V
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R
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---
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---
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A
F
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A
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F
D
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D
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M
A
V
H
L
P
L
S
A
E
A
Q
A
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A
R
I
L
M
L
S
S
N
N
I
L
S
P
A
S
G
R
P
L
A
M
P
R
L
D
M
V
T
G
L
Y
Y
L
T
T
E
V
P
G
D
T
G
E
Y
Q
P
A
S
G
DHP
E
T
G
----------
V
Y
S
S
P
A
E
A
I
M
A
A
D
R
G
V
L
S
V
R
A
K
I
K
V
--
R
L
T
Q
---
L
--------------
R
-
P
P
V
E
I
E
A
E
L
FGHS
G
W
QP
G
D
A
-------
W
M
A
E
--
T
T
L
-
G
R
V
M
-
F
N
E
L
L
P
L
G
Y
P
F
V
N
--------------------------------------
K
Q
M
H
K
K
V
Q
A
A
I
I
N
D
L
A
E
R
Y
P
M
I
V
V
A
Q
T
V
D
K
L
K
D
A
G
F
Y
W
A
T
R
S
G
V
T
V
S
M
A
D
V
L
V
P
P
R
K
K
E
I
L
D
H
Y
E
E
R
A
D
K
V
E
K
Q
F
Q
R
G
A
L
N
H
D
E
R
N
E
A
L
V
E
I
W
K
E
A
T
D
E
V
G
Q
A
L
R
E
H
Y
P
D
D
---------------
N
P
I
I
T
I
V
D
S
G
A
T
G
N
F
T
Q
T
R
T
L
A
G
M
K
G
L
V
T
N
P
K
G
E
F
I
P
R
P
V
K
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
N
T
H
G
A
R
K
G
L
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
R
L
V
D
V
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Q
D
V
I
V
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Q
T
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R
G
I
V
V
E
L
A
E
R
A
P
D
G
T
L
I
R
-----
D
P
Y
I
--------
E
-----
T
S
A
Y
A
R
----
T
L
G
T
D
A
V
D
E
-
A
G
N
V
I
V
E
R
G
Q
D
L
----
G
D
P
E
I
D
A
L
--
L
A
----
A
G
----
I
T
Q
V
K
V
R
S
V
L
T
C
A
T
S
T
G
V
C
A
T
C
Y
G
R
S
M
A
T
G
K
L
V
D
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
G
G
L
P
R
V
Q
E
L
F
E
A
R
V
P
R
G
K
A
P
I
A
D
V
T
G
R
V
--------
R
L
E
D
G
E
R
---
F
Y
-
K
I
T
---
I
V
P
D
D
G
G
E
E
V
V
Y
D
K
I
SK
R
Q
R
L
R
V
F
K
H
E
D
G
S
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R
V
L
S
D
G
D
H
V
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V
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Q
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L
M
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G
S
A
D
P
H
E
V
L
R
V
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G
P
R
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V
Q
I
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L
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R
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Y
R
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Q
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V
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I
H
D
K
H
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E
V
I
V
R
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M
L
R
R
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T
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S
T
E
F
L
P
G
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L
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D
R
A
E
F
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A
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N
R
R
V
V
A
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G
G
E
P
A
A
G
R
P
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L
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I
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K
A
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L
A
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W
L
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F
Q
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T
R
V
L
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A
A
I
N
C
R
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D
K
L
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L
K
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N
V
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K
L
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T
G
I
N
R
Y
R
N
I
A
V
Q
P
T
E
E
A
R
A
A
----------------------
53
PsiBlast_CBE
70.22
49%
27
- C5 -
-
5E17
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
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L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
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V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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G
A
P
E
I
I
I
R
N
E
K
R
M
L
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A
V
D
A
L
L
D
N
G
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R
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A
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V
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N
P
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D
-
R
P
L
R
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L
T
D
I
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K
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F
R
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N
L
L
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K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
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A
L
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L
F
K
P
F
L
L
K
K
M
E
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G
I
A
P
N
V
K
A
A
R
R
M
L
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R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
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K
V
V
L
L
N
R
A
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A
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L
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P
S
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D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
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Q
D
V
V
--
T
V
R
Y
M
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L
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R
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L
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A
R
I
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A
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--
A
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E
D
E
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V
A
W
E
L
I
Q
L
D
---
V
P
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S
L
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Q
A
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R
L
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L
L
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Y
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T
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T
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P
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K
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Y
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A
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Q
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M
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F
L
T
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R
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R
Y
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Q
L
W
T
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T
T
E
K
V
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Q
A
V
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K
N
F
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N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
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P
Q
Q
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G
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Y
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V
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P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
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C
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D
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P
V
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I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
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I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
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A
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A
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Y
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Y
R
A
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G
V
K
L
H
D
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H
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I
V
V
R
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M
M
K
Y
V
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V
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D
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R
L
L
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L
E
K
W
D
V
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A
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N
E
R
L
I
A
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K
T
P
V
A
W
K
P
L
L
M
G
V
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S
A
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S
W
L
S
A
A
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F
Q
N
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H
V
L
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A
G
K
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D
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L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
51
PsiBlast_CBE
70.21
49%
27
- C5 -
-
5I2D
1
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
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A
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K
R
L
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V
R
A
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S
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N
R
P
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I
L
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V
P
V
L
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P
M
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G
G
R
F
A
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D
L
N
D
L
Y
R
R
L
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N
R
N
N
R
L
K
K
L
L
A
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G
A
P
E
I
I
I
R
N
E
K
R
M
L
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A
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D
A
L
L
D
N
G
R
R
G
A
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V
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N
P
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D
-
R
P
L
R
S
L
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K
Q
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F
R
Q
N
L
L
G
K
R
V
D
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G
R
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V
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V
V
G
P
Q
L
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L
H
Q
C
G
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A
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L
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P
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L
L
K
K
M
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E
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G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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---
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--------------
G
R
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---------
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-------
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----
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---------------
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--------
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--------
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---
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---
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--
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------------
F
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K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
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V
T
D
P
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D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
57
PsiBlast_CBE
70.06
49%
26
- C5 -
-
5D4C
3
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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T
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S
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A
D
F
D
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D
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L
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A
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A
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M
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A
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N
L
L
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A
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P
L
A
K
P
S
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D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
R
Y
M
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K
R
L
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T
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P
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R
I
L
F
A
R
I
V
A
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--
A
V
E
D
E
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V
A
W
E
L
I
Q
L
D
---
V
P
Q
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K
N
S
L
K
D
L
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Y
Q
A
F
L
R
L
G
M
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T
A
R
L
L
D
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Y
Y
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T
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T
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P
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K
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Y
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A
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Y
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M
G
F
L
T
D
R
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R
Y
D
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I
L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
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L
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L
M
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L
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A
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G
G
A
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T
A
L
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Y
L
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K
L
V
D
V
T
H
E
I
V
V
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E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
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K
C
Y
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Y
D
L
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M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
G
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P
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A
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D
P
H
Q
L
L
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A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
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A
A
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A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
52
PsiBlast_CBE
70.02
49%
25
- C5 -
-
5E18
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
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G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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T
L
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L
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I
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A
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Q
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V
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V
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S
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L
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C
E
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N
A
D
F
D
G
D
Q
M
A
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L
S
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F
A
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A
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A
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L
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A
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L
A
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P
S
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D
I
I
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G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
R
Y
M
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K
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L
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R
I
L
F
A
R
I
V
A
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--
A
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E
D
E
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V
A
W
E
L
I
Q
L
D
---
V
P
Q
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K
N
S
L
K
D
L
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Y
Q
A
F
L
R
L
G
M
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A
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L
L
D
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Y
Y
G
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T
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I
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D
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K
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Y
L
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A
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Y
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M
G
F
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D
R
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R
Y
D
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L
Q
L
W
T
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T
T
E
K
V
T
Q
A
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K
N
F
E
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N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
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P
Q
Q
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L
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A
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K
G
G
A
D
T
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L
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Y
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L
V
D
V
T
H
E
I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
54
PsiBlast_CBE
69.94
49%
26
- C5 -
-
5D4E
1
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
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R
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V
R
A
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N
R
P
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M
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L
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A
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P
V
L
P
P
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L
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P
M
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D
G
G
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F
A
T
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D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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G
A
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E
I
I
I
R
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K
R
M
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Q
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A
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D
A
L
L
D
N
G
R
R
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A
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V
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N
P
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D
-
R
P
L
R
S
L
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N
L
L
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D
Y
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G
R
S
V
I
V
V
G
P
Q
L
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L
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Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
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V
I
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K
V
V
L
L
N
R
A
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L
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V
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V
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S
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L
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C
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A
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F
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D
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A
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L
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G
----------
A
G
L
----------
E
F
A
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A
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A
A
H
E
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G
E
V
A
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N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
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Y
M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
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A
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--
A
V
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D
E
K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
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K
N
S
L
K
D
L
V
Y
Q
A
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L
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L
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M
E
K
T
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L
L
D
A
L
K
Y
Y
G
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T
T
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G
I
D
D
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V
I
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E
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K
Q
Y
L
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K
L
L
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A
Y
E
M
G
F
L
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R
Y
D
Q
I
L
Q
L
W
T
E
T
T
E
K
V
T
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A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
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L
R
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Q
K
P
S
G
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S
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L
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V
L
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Y
F
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S
H
G
A
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G
A
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A
L
R
T
A
D
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Y
L
T
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L
V
D
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T
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V
V
R
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A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
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Y
D
L
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A
V
G
I
V
A
A
Q
S
I
G
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P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
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V
I
E
L
F
E
A
R
R
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A
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D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
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L
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K
E
A
R
L
L
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K
D
G
D
Y
V
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Y
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I
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V
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M
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L
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L
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L
I
A
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A
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L
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A
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L
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G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
72
PsiBlast_CBE
69.89
49%
25
- C5 -
-
4G7O
3
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
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E
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M
K
H
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A
-
R
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A
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V
R
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N
R
P
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W
M
I
L
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P
V
L
P
P
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L
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D
G
G
R
F
A
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D
L
N
D
L
Y
R
R
L
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N
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N
N
R
L
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K
L
L
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A
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N
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-
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L
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D
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V
I
V
V
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L
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C
G
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A
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L
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L
L
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K
---
D
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Y
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K
K
G
----------
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G
L
----------
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A
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P
E
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A
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A
A
H
E
R
G
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V
A
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N
A
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I
K
V
AG
R
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T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
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A
L
L
--
A
V
A
-
H
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V
D
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V
V
--
T
V
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R
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A
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A
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--
A
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D
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V
A
W
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L
I
Q
L
D
---
V
P
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Q
A
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M
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F
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R
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L
W
T
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T
T
E
K
V
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A
V
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K
N
F
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E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
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Q
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L
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Y
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L
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Q
P
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--
V
-------
T
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S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
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A
GE
I
Q
E
V
P
V
R
S
P
L
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C
Q
T
R
Y
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L
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I
G
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A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
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I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
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Y
K
L
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K
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A
R
L
L
V
K
D
G
D
Y
V
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A
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A
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L
L
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A
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A
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Y
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E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
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D
S
R
L
L
E
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Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
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K
S
A
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T
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S
W
L
S
A
A
S
F
Q
N
T
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H
V
L
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A
A
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A
G
K
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D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
62
PsiBlast_CBE
69.88
49%
25
- C5 -
-
4OIR
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
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A
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V
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R
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V
L
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A
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D
L
N
D
L
Y
R
R
L
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N
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N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
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K
R
M
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A
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D
A
L
L
D
N
G
R
R
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A
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V
T
N
P
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D
-
R
P
L
R
S
L
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N
L
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R
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D
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R
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V
I
V
V
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P
Q
L
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L
H
Q
C
G
L
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A
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L
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F
L
L
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K
M
E
E
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G
I
A
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A
A
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R
M
L
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Q
RDI
K
---
D
E
V
W
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A
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V
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K
V
V
L
L
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R
A
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---
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--------------
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---------
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-------
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A
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A
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---
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-------
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------------------------
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G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
56
PsiBlast_CBE
69.77
49%
25
- C5 -
-
5D4C
1
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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V
L
V
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S
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L
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A
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A
D
F
D
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D
Q
M
A
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A
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A
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Q
M
L
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A
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N
L
L
S
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A
S
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L
A
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P
S
R
D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
R
Y
M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
V
A
E
--
A
V
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D
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K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
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K
N
S
L
K
D
L
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Y
Q
A
F
L
R
L
G
M
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K
T
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L
L
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A
L
K
Y
Y
G
F
T
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T
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D
D
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P
E
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K
Q
Y
L
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K
L
L
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Y
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M
G
F
L
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R
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R
Y
D
Q
I
L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
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L
R
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L
M
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K
P
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G
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V
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S
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L
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V
L
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Y
F
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H
G
A
R
K
G
G
A
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T
A
L
R
T
A
D
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Y
L
T
R
K
L
V
D
V
T
H
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I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
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Y
D
L
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A
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P
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S
I
G
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A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
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A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
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A
A
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A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
50
PsiBlast_CBE
69.68
49%
27
- C5 -
-
5I2D
1
RPOC_THET8
O:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
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V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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G
A
P
E
I
I
I
R
N
E
K
R
M
L
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E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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T
L
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L
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I
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L
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A
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D
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A
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M
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A
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N
L
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A
S
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E
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L
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P
S
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D
I
I
L
G
L
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Y
I
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V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
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M
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K
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T
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G
R
I
L
F
A
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A
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--
A
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D
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K
V
A
W
E
L
I
Q
L
D
---
V
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Q
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S
L
K
D
L
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Y
Q
A
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M
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L
L
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A
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K
Y
Y
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F
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T
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I
D
D
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V
I
P
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K
Q
Y
L
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K
L
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M
G
F
L
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Y
D
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L
W
T
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K
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K
N
F
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YPF------------
N
P
L
Y
V
M
A
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A
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P
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Y
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H
G
A
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K
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G
A
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Y
L
T
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L
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D
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I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
64
PsiBlast_CBE
69.66
49%
26
- C5 -
-
4OIP
3
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
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V
R
A
F
L
D
S
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N
R
P
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W
M
I
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A
V
P
V
L
P
P
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L
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P
M
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V
D
G
G
R
F
A
T
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D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
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A
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V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
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K
Q
G
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F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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T
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I
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L
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C
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A
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N
A
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D
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G
----------
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A
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A
A
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E
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G
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V
A
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N
A
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I
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V
AG
R
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T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
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-------
E
A
L
L
--
A
V
A
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H
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V
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---
V
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A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
G
L
R
G
L
M
Q
K
P
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G
E
T
F
E
V
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V
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S
S
F
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L
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L
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F
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G
A
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K
G
G
A
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L
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Y
L
T
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L
V
D
V
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I
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V
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A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
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Y
D
L
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M
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I
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E
A
V
G
I
V
A
A
Q
S
I
G
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P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
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V
I
E
L
F
E
A
R
R
P
K
A
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A
V
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S
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I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
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Y
K
L
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K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
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P
L
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Y
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V
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E
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Q
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A
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K
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I
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V
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M
M
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Y
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L
L
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L
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W
D
V
E
A
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N
E
R
L
I
A
E
G
K
T
P
V
A
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K
P
L
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M
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K
S
A
L
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S
W
L
S
A
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Q
N
T
T
H
V
L
T
E
A
A
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A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
70
PsiBlast_CBE
69.64
49%
25
- C5 -
-
4G7Z
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
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A
R
K
R
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V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
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P
M
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V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
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N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
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I
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N
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A
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N
G
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A
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N
P
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D
-
R
P
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L
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R
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N
L
L
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D
Y
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G
R
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V
I
V
V
G
P
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L
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L
H
Q
C
G
L
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A
L
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L
F
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P
F
L
L
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M
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A
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RDI
K
---
D
E
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V
V
L
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Y
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K
K
G
----------
A
G
L
----------
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A
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P
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A
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A
A
H
E
R
G
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A
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A
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K
V
AG
R
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T
S
---
V
--------------
G
R
L
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Y
V
---------
F
A
--
N
P
D
-------
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A
L
L
--
A
V
A
-
H
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--
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A
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--
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L
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D
---
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L
W
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T
T
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V
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A
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N
F
E
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N
YPF------------
N
P
L
Y
V
M
A
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S
G
A
R
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N
P
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Q
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L
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--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
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L
----
Y
G
R
V
L
A
R
E
V
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V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
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A
GE
I
Q
E
V
P
V
R
S
P
L
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C
Q
T
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Y
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I
G
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A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
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A
V
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D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
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L
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A
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A
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Y
L
V
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E
I
Q
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V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
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I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
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D
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R
L
L
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V
L
E
K
W
D
V
E
A
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N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
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K
S
W
L
S
A
A
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F
Q
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L
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A
G
K
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D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
74
PsiBlast_CBE
69.62
49%
26
- C5 -
-
4G7H
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
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K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
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A
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R
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V
R
A
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L
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N
R
P
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M
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A
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P
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L
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D
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F
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D
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N
D
L
Y
R
R
L
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N
R
N
N
R
L
K
K
L
L
A
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G
A
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E
I
I
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A
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A
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G
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A
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V
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N
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D
-
R
P
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L
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N
L
L
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K
R
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D
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S
G
R
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V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
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A
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L
F
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P
F
L
L
K
K
M
E
E
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G
I
A
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N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
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A
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V
I
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K
V
V
L
L
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R
A
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I
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Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
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F
A
T
P
E
E
A
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A
A
H
E
R
G
E
V
A
L
N
A
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I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
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A
L
L
--
A
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A
-
H
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I
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D
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--
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V
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A
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I
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A
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--
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L
I
Q
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D
---
V
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Q
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L
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K
Q
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M
G
F
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L
W
T
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T
T
E
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Q
A
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F
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YPF------------
N
P
L
Y
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M
A
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S
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A
R
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P
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Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
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Y
D
L
S
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A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
G
Q
P
L
T
R
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A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
73
PsiBlast_CBE
69.61
49%
24
- C5 -
-
4G7H
2
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
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A
V
P
V
L
P
P
D
L
R
P
M
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Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
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D
-
R
P
L
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L
T
D
I
L
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K
Q
G
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L
L
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D
Y
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V
I
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V
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A
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K
---
D
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L
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D
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D
Q
M
A
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V
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L
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A
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A
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A
R
I
Q
M
L
S
A
H
N
L
L
S
P
A
S
G
E
P
L
A
K
P
S
R
D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
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Y
M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
V
A
E
--
A
V
E
D
E
K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
E
K
N
S
L
K
D
L
V
Y
Q
A
F
L
R
L
G
M
E
K
T
A
R
L
L
D
A
L
K
Y
Y
G
F
T
F
S
T
T
S
G
I
T
I
G
I
D
D
A
V
I
P
E
E
K
K
Q
Y
L
E
E
A
D
R
K
L
L
Q
I
E
Q
A
Y
E
M
G
F
L
T
D
R
E
R
Y
D
Q
I
L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
G
L
R
G
L
M
Q
K
P
S
G
E
T
F
E
V
P
V
R
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
S
S
H
G
A
R
K
G
G
A
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T
A
L
R
T
A
D
S
G
Y
L
T
R
K
L
V
D
V
T
H
E
I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
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A
K
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P
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A
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Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
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V
T
D
P
G
D
S
R
L
L
E
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Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
63
PsiBlast_CBE
69.60
49%
25
- C5 -
-
4OIQ
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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T
L
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L
G
I
Q
A
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V
L
V
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S
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L
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C
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A
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N
A
D
F
D
G
D
Q
M
A
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L
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S
F
A
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A
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A
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I
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M
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S
A
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N
L
L
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P
A
S
G
E
P
L
A
K
P
S
R
D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
R
Y
M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
V
A
E
--
A
V
E
D
E
K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
E
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N
S
L
K
D
L
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Y
Q
A
F
L
R
L
G
M
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K
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A
R
L
L
D
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K
Y
Y
G
F
T
F
S
T
T
S
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T
I
G
I
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V
I
P
E
E
K
K
Q
Y
L
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E
A
D
R
K
L
L
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I
E
Q
A
Y
E
M
G
F
L
T
D
R
E
R
Y
D
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L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
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L
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L
R
G
L
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F
R
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L
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G
G
A
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A
L
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Y
L
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K
L
V
D
V
T
H
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I
V
V
R
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A
D
C
G
T
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N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
M
--------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
G
Q
P
L
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G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
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R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
47
PsiBlast_CBE
69.59
49%
25
- C5 -
-
5VO8
4
?
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
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V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
Q
P
V
L
V
E
G
Q
S
I
Q
L
H
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L
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C
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A
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N
A
D
F
D
G
D
Q
M
A
V
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L
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F
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A
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L
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A
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D
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Y
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K
E
K
K
G
----------
A
G
L
----------
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F
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A
A
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E
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G
E
V
A
L
N
A
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I
K
V
AG
R
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T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
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R
L
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A
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--
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V
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---
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S
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N
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V
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Y
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L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRK
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
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V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
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Y
G
V
C
Q
K
C
Y
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Y
D
L
S
M
A
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P
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S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
-------------------------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
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I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
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Y
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L
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K
E
A
R
L
L
V
K
D
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Y
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Y
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V
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M
M
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Y
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L
L
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V
L
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K
W
D
V
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A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
55
PsiBlast_CBE
69.58
49%
26
- C5 -
-
5D4E
3
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
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V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
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N
E
K
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M
L
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A
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A
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G
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A
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V
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N
P
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D
-
R
P
L
R
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L
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D
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R
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N
L
L
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D
Y
S
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R
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V
I
V
V
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L
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L
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G
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A
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L
F
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L
L
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A
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K
---
D
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V
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K
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----------
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L
----------
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A
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A
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A
A
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E
R
G
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A
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A
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K
V
AG
R
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T
S
---
V
--------------
G
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Y
V
---------
F
A
--
N
P
D
-------
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A
L
L
--
A
V
A
-
H
G
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D
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V
V
--
T
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L
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A
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A
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--
A
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V
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L
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Q
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D
---
V
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A
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L
W
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T
T
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V
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N
F
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YPF------------
N
P
L
Y
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M
A
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S
G
A
R
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P
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Y
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L
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P
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--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
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L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
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A
GE
I
Q
E
V
P
V
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S
P
L
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C
Q
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Y
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A
V
G
I
V
A
A
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S
I
G
E
P
G
T
Q
L
T
---------------
I
--------
T
Q
G
L
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V
I
E
L
F
E
A
R
R
P
K
A
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A
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D
G
-
V
--------
V
R
I
E
E
---
T
E
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K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
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Y
K
L
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K
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A
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L
L
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D
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D
Y
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A
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Y
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V
Y
R
A
Q
G
V
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L
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D
K
H
I
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I
V
V
R
Q
M
M
K
Y
V
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V
T
D
P
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D
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R
L
L
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Q
V
L
E
K
W
D
V
E
A
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N
E
R
L
I
A
E
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K
T
P
V
A
W
K
P
L
L
M
G
V
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K
S
A
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S
W
L
S
A
A
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Q
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L
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A
A
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A
G
K
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D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
66
PsiBlast_CBE
69.49
49%
25
- C5 -
-
4OIN
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
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K
E
L
L
E
E
M
K
H
P
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A
-
R
R
A
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A
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R
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M
I
L
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V
L
P
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A
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D
L
N
D
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Y
R
R
L
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N
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N
N
R
L
K
K
L
L
A
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A
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I
I
I
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K
R
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A
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D
A
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L
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G
R
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A
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N
P
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D
-
R
P
L
R
S
L
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R
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N
L
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R
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D
Y
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R
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V
I
V
V
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P
Q
L
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L
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Q
C
G
L
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A
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L
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K
P
F
L
L
K
K
M
E
E
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G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
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V
I
H
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K
V
V
L
L
N
R
A
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I
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K
E
K
K
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----------
A
G
L
----------
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A
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P
E
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A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
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-------
E
A
L
L
--
A
V
A
-
H
G
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D
L
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--
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V
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A
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I
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A
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--
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L
I
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L
D
---
V
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S
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L
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A
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A
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A
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S
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A
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A
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L
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V
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A
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N
Y
I
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V
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P
L
F
Q
P
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E
--
V
-------
T
R
S
L
--------
R
L
R
K
R
A
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
E
A
GE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
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Y
D
L
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A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
----------------
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
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I
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D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
G
Q
P
L
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R
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A
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D
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Q
L
L
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A
K
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P
E
A
V
E
R
Y
L
V
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E
I
Q
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V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
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D
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R
L
L
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Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
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T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
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K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
40
PsiBlast_CBE
69.45
50%
23
- C5 -
-
4XLN
1
?
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
E
L
L
K
E
L
D
L
E
K
L
E
R
E
L
L
E
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M
K
H
P
S
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A
-
R
R
A
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A
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I
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G
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A
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D
L
N
D
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Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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A
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I
I
I
R
N
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K
R
M
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A
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D
A
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N
G
R
R
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P
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T
N
P
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-
S
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S
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D
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K
Q
G
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F
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N
L
L
G
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R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
A
F
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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T
L
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I
Q
A
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----------
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----------
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---
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--------------
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L
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--
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-------
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RLRKRSDI
E
-----
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L
Y
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R
----
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L
A
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A
--
L
G
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S
----
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----
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G
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-----------------------
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-----
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---
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--
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------------
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----------------------------------------
65
PsiBlast_CBE
69.41
49%
25
- C5 -
-
4OIO
4
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
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M
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A
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Q
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L
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-
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--------------
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-------
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---
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--------
R
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D
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L
----
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----
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--
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----
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GE
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-----------------------
Q
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-
V
--------
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---
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---
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--
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------------
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L
I
P
A
G
T
G
----------------------------------------
69
PsiBlast_CBE
69.28
49%
26
- C5 -
-
4G7Z
2
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
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A
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Q
Q
L
L
K
E
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A
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L
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N
V
I
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L
I
P
A
G
T
G
----------------------------------------
39
PsiBlast_CBE
69.14
50%
23
- C5 -
-
4XLN
1
?
J:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
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Q
E
L
L
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K
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----------
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---
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--------------
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-------
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--
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-------
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E
-----
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Y
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R
----
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L
A
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A
--
L
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----
L
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----
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-----------------------
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-----
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---
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--
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------------
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V
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L
I
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A
G
T
G
----------------------------------------
71
PsiBlast_CBE
69.07
49%
24
- C5 -
-
4G7O
3
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
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-
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L
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R
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---
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--------------
G
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-------
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L
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--
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-------
T
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--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
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V
L
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V
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L
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Y
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----
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--
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----
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-------
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A
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A
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D
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--------
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-
V
--------
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---
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---
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--
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------------
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Y
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L
K
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N
V
I
L
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R
L
I
P
A
G
T
G
----------------------------------------
61
PsiBlast_CBE
68.76
49%
21
- C5 -
-
4Q5S
3
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
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K
---
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---
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--------------
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F
A
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--
A
V
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D
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V
A
W
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L
I
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L
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---
V
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N
F
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N
P
L
Y
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M
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A
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G
N
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Q
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Q
L
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--
V
-------
T
R
S
L
--------
R
LRK
R
A
D
I
E
A
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L
----
Y
G
R
V
L
A
R
E
V
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V
L
G
V
R
L
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Y
L
----
S
M
D
D
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H
L
L
--
I
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----
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A
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A
GE
I
Q
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V
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M
------------------------
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-
V
--------
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---
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---
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--
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------------
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L
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N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
81
PsiBlast_CBE
68.26
49%
25
- C5 -
-
3AOI
1
RPOC_THET8
I:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
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M
K
H
P
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R
A
-
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R
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R
P
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M
I
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V
P
V
L
P
P
D
L
R
------------
S
D
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N
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---
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---
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--------------
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---
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N
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--
V
-------
T
R
S
L
--------
R
LRKRA
D
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A
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L
----
Y
G
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V
L
A
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L
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V
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Y
L
----
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M
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D
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H
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L
--
I
K
----
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----------------------
T
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A
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-
V
--------
V
R
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---
T
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---
V
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--
S
E
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------------
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L
L
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D
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V
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M
M
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Y
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L
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V
L
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W
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A
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W
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A
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V
I
L
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R
L
I
P
A
G
T
G
----------------------------------------
33
PsiBlast_CBE
68.26
50%
23
- C5 -
-
4XLR
1
RPOC_THEAQ
J:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
E
L
L
K
E
L
D
L
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K
H
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A
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A
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L
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D
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L
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G
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M
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RDI
K
---
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A
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---
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--------------
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-------
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A
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F
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D
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--
V
-------
T
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RLRKRSDI
E
-----
S
G
L
Y
G
R
----
V
L
A
R
E
V
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A
--
L
G
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Y
L
S
----
L
E
D
V
H
F
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A
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----
A
G
E---
V
R
E
V
P
V
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V
V
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A
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Q
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T
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-----------------------
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A
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R-------
I
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L
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-----
V
F
---
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--
S
E
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------------
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H
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E
I
V
V
R
Q
M
L
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Y
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L
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V
L
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L
I
A
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K
V
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V
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P
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K
S
A
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K
S
W
L
S
A
A
S
F
Q
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H
V
L
T
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A
A
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A
G
K
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D
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L
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G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
89
PsiBlast_CBE
68.11
49%
25
- C5 -
-
2O5I
3
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
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K
R
M
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A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
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S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
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L
K
L
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Q
C
G
L
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K
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A
L
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L
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K
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F
L
L
K
K
M
E
E
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G
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A
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N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
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K
V
V
L
L
N
R
A
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V
L
V
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I
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L
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P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
V
P
L
S
S
F
A
Q
A
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A
R
I
Q
M
L
S
A
H
N
L
L
S
P
A
S
G
E
P
L
A
K
P
S
R
D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
R
Y
M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
V
A
E
--
A
V
E
D
E
K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
E
K
N
S
L
K
D
L
V
Y
Q
A
F
L
R
L
G
M
E
K
T
A
R
L
L
D
A
L
K
Y
Y
G
F
T
F
S
T
T
S
G
I
T
I
G
I
D
D
A
V
I
P
E
E
K
K
Q
Y
L
E
E
A
D
R
K
L
L
Q
I
E
Q
A
Y
E
M
G
F
L
T
D
R
E
R
Y
D
Q
I
L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
G
L
R
G
L
M
Q
K
P
S
G
E
T
F
E
V
P
V
R
S
S
F
R
E
G
L
T
V
L
E
Y
F
I
S
S
H
G
A
R
K
G
G
A
D
T
A
L
R
T
A
D
S
G
Y
L
T
R
K
L
V
D
V
T
H
E
I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
---------------------------
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
82
PsiBlast_CBE
67.74
49%
27
- C5 -
-
3AOI
2
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
-----------
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
Q
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V
L
V
E
G
Q
S
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
V
P
L
S
S
F
A
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A
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A
R
I
Q
M
L
S
A
H
N
L
L
S
P
A
S
G
E
P
L
A
K
P
S
R
D
I
I
L
G
L
Y
Y
I
T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
T
P
E
E
A
L
A
A
H
E
R
G
E
V
A
L
N
A
P
I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
L
Q
D
V
V
--
T
V
R
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M
G
K
R
L
E
T
S
P
G
R
I
L
F
A
R
I
V
A
E
--
A
V
E
D
E
K
V
A
W
E
L
I
Q
L
D
---
V
P
Q
E
K
N
S
L
K
D
L
V
Y
Q
A
F
L
R
L
G
M
E
K
T
A
R
L
L
D
A
L
K
Y
Y
G
F
T
F
S
T
T
S
G
I
T
I
G
I
D
D
A
V
I
P
E
E
K
K
Q
Y
L
E
E
A
D
R
K
L
L
Q
I
E
Q
A
Y
E
M
G
F
L
T
D
R
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R
Y
D
Q
I
L
Q
L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
P
Q
Q
I
R
Q
L
C
G
L
R
G
L
M
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P
S
G
E
T
F
E
V
P
V
R
S
S
F
R
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G
L
T
V
L
E
Y
F
I
S
S
H
G
A
R
K
G
G
A
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T
A
L
R
T
A
D
S
G
Y
L
T
R
K
L
V
D
V
T
H
E
I
V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
--------------
D
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
34
PsiBlast_CBE
67.72
50%
23
- C5 -
-
4XLR
1
RPOC_THEAQ
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
E
L
L
K
E
L
D
L
E
K
L
E
R
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
V
I
D
N
G
R
R
G
S
P
V
T
N
P
G
-
S
E
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
A
F
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
P
T
L
H
R
L
G
I
Q
A
F
Q
P
V
L
V
E
G
Q
S
I
Q
L
H
P
L
V
C
E
A
F
N
A
D
F
D
G
D
Q
M
A
V
H
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L
S
S
F
A
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A
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A
R
I
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M
L
S
A
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N
L
L
S
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A
S
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E
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L
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S
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D
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I
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L
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Y
I
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V
R
K
E
K
K
G
----------
A
G
M
----------
A
F
A
T
P
E
E
A
L
A
A
Y
E
R
G
E
V
A
L
N
A
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I
V
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
F
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
H
G
L
L
D
-
L
Q
D
V
V
--
T
V
R
Y
L
G
R
R
L
E
-----
T
S
P
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R
I
L
F
A
RI
V
G
E
A
V
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D
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V
A
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QMD
V
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N
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L
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D
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Q
A
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M
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A
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A
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L
W
T
E
T
T
E
K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
R
G
N
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L
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A
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A
L
R
T
A
D
S
G
Y
L
T
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K
L
V
D
V
A
H
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I
V
V
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E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
M
D
E
--
V
-------
T
R
T
L
RLRKRSDI
E
-----
S
G
L
Y
G
R
----
V
L
A
R
E
V
E
A
--
L
G
R
R
L
E
E
G
R
Y
L
S
----
L
E
D
V
H
F
L
I
KA
A
E
----
A
G
E---
V
R
E
V
P
V
R
S
P
L
T
C
Q
T
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Y
G
V
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C
Y
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Y
D
L
S
M
A
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P
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I
G
E
A
V
G
V
V
A
A
E
S
I
G
E
P
G
T
Q
L
T
M
-----------------------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
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A
V
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S
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I
D
G
V
V
R-------
I
E
E
G
E
D
R
L
S
-----
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
D
A
R
L
L
V
K
D
G
D
Y
V
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A
G
Q
P
L
T
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A
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D
P
H
Q
L
L
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A
K
G
P
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A
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Y
L
V
D
E
I
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K
V
Y
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A
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G
V
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L
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I
V
V
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M
L
K
Y
V
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V
T
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R
L
L
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V
L
E
K
W
D
V
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A
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N
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R
L
I
A
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K
V
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
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S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
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A
A
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A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
88
PsiBlast_CBE
67.71
49%
26
- C5 -
-
2O5I
3
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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G
A
P
E
I
I
I
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N
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K
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A
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D
A
L
L
D
N
G
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A
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V
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N
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D
-
R
P
L
R
S
L
T
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F
R
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N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
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A
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L
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P
F
L
L
K
K
M
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V
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R
M
L
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RDI
K
---
D
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V
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L
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P
S
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D
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I
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G
L
Y
Y
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T
Q
V
R
K
E
K
K
G
----------
A
G
L
----------
E
F
A
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P
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A
L
A
A
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R
G
E
V
A
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N
A
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V
AG
R
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T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
I
V
D
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Q
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V
--
T
V
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Y
M
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K
R
L
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T
S
P
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F
A
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A
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--
A
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K
V
A
W
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L
I
Q
L
D
---
V
P
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N
S
L
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L
R
L
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L
L
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L
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L
L
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R
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Y
D
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L
W
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T
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K
V
T
Q
A
V
F
K
N
F
E
E
N
YPF------------
N
P
L
Y
V
M
A
Q
S
G
A
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G
N
P
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V
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A
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G
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T
N
Y
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-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
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V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
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Y
G
V
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K
C
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D
L
S
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A
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S
I
G
E
A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
---------------------------
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
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A
G
Q
P
L
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A
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D
P
H
Q
L
L
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A
K
G
P
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A
V
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Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
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F
Q
N
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H
V
L
T
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A
A
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A
G
K
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D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
80
PsiBlast_CBE
67.65
49%
25
- C5 -
-
3AOI
1
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
-----------
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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G
A
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I
I
I
R
N
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K
R
M
L
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A
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L
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N
G
R
R
G
A
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V
T
N
P
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-
R
P
L
R
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L
T
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I
L
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G
K
Q
G
R
F
R
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N
L
L
G
K
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V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
A
A
R
R
M
L
E
R
Q
RDI
K
---
D
E
V
W
D
A
L
E
E
V
I
H
G
K
V
V
L
L
N
R
A
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L
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L
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C
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A
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A
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D
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D
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L
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M
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A
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N
L
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A
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E
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L
A
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P
S
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D
I
I
L
G
L
Y
Y
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Q
V
R
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E
K
K
G
----------
A
G
L
----------
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F
A
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E
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A
L
A
A
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E
R
G
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A
L
N
A
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I
K
V
AG
R
E
T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
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A
L
L
--
A
V
A
-
H
G
I
V
D
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Q
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V
V
--
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L
F
A
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A
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--
A
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V
A
W
E
L
I
Q
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---
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D
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Q
A
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L
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Y
Y
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D
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K
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Y
L
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A
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R
K
L
L
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A
Y
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M
G
F
L
T
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Y
D
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I
L
Q
L
W
T
E
T
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K
V
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A
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F
K
N
F
E
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N
YPF------------
N
P
L
Y
V
M
A
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S
G
A
R
G
N
P
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Q
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Y
L
T
R
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L
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D
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V
V
R
E
A
D
C
G
T
T
N
Y
I
S
V
-
P
L
F
Q
P
D
E
--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
R
V
L
A
R
E
V
E
V
L
G
V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
EAGE
I
Q
E
V
P
V
R
S
P
L
T
C
Q
T
R
Y
G
V
C
Q
K
C
Y
G
Y
D
L
S
M
A
R
P
V
S
I
G
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A
V
G
I
V
A
A
Q
S
I
G
E
P
G
T
Q
L
T
--------------
D
I
--------
T
Q
G
L
P
R
V
I
E
L
F
E
A
R
R
P
K
A
K
A
V
I
S
E
I
D
G
-
V
--------
V
R
I
E
E
---
T
E
E
K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
E
Y
K
L
P
K
E
A
R
L
L
V
K
D
G
D
Y
V
E
A
G
Q
P
L
T
R
G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
G
D
S
R
L
L
E
G
Q
V
L
E
K
W
D
V
E
A
L
N
E
R
L
I
A
E
G
K
T
P
V
A
W
K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
44
PsiBlast_CBE
67.43
49%
10
- C5 -
-
5X22
2
?
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
E
V
V
R
A
F
L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
V
Q
V
D
G
G
R
F
A
T
S
D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
Q
G
A
P
E
I
I
I
R
N
E
K
R
M
L
Q
E
A
V
D
A
L
L
D
N
G
R
R
G
A
P
V
T
N
P
G
S
D
-
R
P
L
R
S
L
T
D
I
L
S
G
K
Q
G
R
F
R
Q
N
L
L
G
K
R
V
D
Y
S
G
R
S
V
I
V
V
G
P
Q
L
K
L
H
Q
C
G
L
P
K
R
M
A
L
E
L
F
K
P
F
L
L
K
K
M
E
E
K
G
I
A
P
N
V
K
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K
---
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----------
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L
----------
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---
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--------------
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-------
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--
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---
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I
D
D
A
------------------------------------------------------------F--------------
N
P
L
Y
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P
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LRK
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----
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----
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--
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------------
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----------------------------------------
86
PsiBlast_CBE
66.44
49%
24
- C5 -
-
2O5J
4
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
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A
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A
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L
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K
---
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---
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--------------
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-------
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L
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--
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-------
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--------
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LRKRA
D
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----
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----
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I
--------
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Q
G
L
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R
V
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F
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A
R
R
P
K
A
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--------------------------------------------------------------------------------------
A
I
D
P
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Q
L
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V
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L
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A
G
T
G
----------------------------------------
87
PsiBlast_CBE
66.10
49%
21
- C5 -
-
2O5J
4
RPOC_THET8
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
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A
I
Q
Q
L
L
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E
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D
L
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K
---
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--------------------------------------------------------------------------------------
A
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A
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K
P
L
L
M
G
V
T
K
S
A
L
S
T
K
S
W
L
S
A
A
S
F
Q
N
T
T
H
V
L
T
E
A
A
I
A
G
K
K
D
E
L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
60
PsiBlast_CBE
64.41
49%
26
- C5 -
-
4WQS
2
RPOC_THET8
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
E
K
E
L
L
E
E
M
K
H
P
S
R
A
-
R
R
A
K
A
R
K
R
L
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V
V
R
A
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L
D
S
G
N
R
P
E
W
M
I
L
E
A
V
P
V
L
P
P
D
L
R
P
M
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V
D
G
G
R
F
A
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D
L
N
D
L
Y
R
R
L
I
N
R
N
N
R
L
K
K
L
L
A
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G
A
P
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I
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K
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V
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N
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-
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L
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N
L
L
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V
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Y
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G
R
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V
I
V
V
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Q
L
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L
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Q
C
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K
---
D
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V
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N
L
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V
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----------
A
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L
----------
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R
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S
---
V
--------------
G
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V
---------
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--
N
P
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-------
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A
L
L
--
A
V
A
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--
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L
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---
V
P
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A
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M
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N
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Q
--------------------
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--
V
-------
T
R
S
L
--------
R
LRKRA
D
I
E
A
G
L
----
Y
G
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V
L
A
R
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V
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V
L
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V
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L
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----
S
M
D
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--
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----
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A
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F
----------------------
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-
V
--------
V
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---
T
E
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L
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---
V
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--
S
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G
------------
F
S
K
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K
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L
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D
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A
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G
L
K
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N
V
I
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R
L
I
P
A
G
T
G
----------------------------------------
45
PsiBlast_CBE
60.89
49%
26
- C5 -
-
5X21
2
?
D:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
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K
E
L
L
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M
K
H
P
S
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A
-
R
R
A
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A
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K
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N
R
P
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I
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V
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R
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N
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-
R
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S
L
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K
Q
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R
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N
L
L
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K
R
V
D
Y
S
G
R
S
V
I
V
V
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Q
L
K
L
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Q
C
G
L
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K
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M
A
L
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F
K
P
F
L
L
K
K
M
E
E
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G
I
A
P
N
V
K
A
A
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R
M
L
E
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Q
RDI
K
---
D
E
V
W
D
A
L
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I
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V
V
L
L
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R
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----------
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L
----------
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E
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A
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A
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E
R
G
E
V
A
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N
A
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I
K
V
AG
R
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T
S
---
V
--------------
G
R
L
K
Y
V
---------
F
A
--
N
P
D
-------
E
A
L
L
--
A
V
A
-
H
G
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D
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--
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---
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A
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YPF------------
N
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Q
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--
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-------
T
R
S
L
--------
R
L
R
K
R
A
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A
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L
----
Y
G
R
V
L
A
R
E
V
E
V
L
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V
R
L
E
E
G
R
Y
L
----
S
M
D
D
V
H
L
L
--
I
K
----
A
A
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A
GE
I
Q
E
V
P
V
R
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P
L
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Y
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C
Y
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L
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I
V
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L
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F
H
T
G
G
V
A
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A
A
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D
I
--------
T
Q
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V
I
E
L
F
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A
R
R
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K
A
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A
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D
G
-
V
--------
V
R
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E
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---
T
E
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K
L
S
V
F
---
V
E
--
S
E
G
------------
F
S
K
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Y
K
L
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K
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A
R
L
L
V
K
D
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D
Y
V
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A
G
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P
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T
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G
A
I
D
P
H
Q
L
L
E
A
K
G
P
E
A
V
E
R
Y
L
V
E
E
I
Q
K
V
Y
R
A
Q
G
V
K
L
H
D
K
H
I
E
I
V
V
R
Q
M
M
K
Y
V
E
V
T
D
P
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D
S
R
L
L
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Q
V
L
E
K
W
D
V
E
A
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N
E
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L
I
A
E
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T
P
V
A
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K
P
L
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M
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K
S
A
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S
W
L
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A
A
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Q
N
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A
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A
G
K
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D
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L
I
G
L
K
E
N
V
I
L
G
R
L
I
P
A
G
T
G
----------------------------------------
43
PsiBlast_CBE
60.72
49%
27
- C5 -
-
5X22
1
?
N:
[451-1477]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
D
A
R
M
G
A
E
A
I
Q
Q
L
L
K
E
L
D
L
E
A
L
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K
E
L
L
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M
K
H
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A
-
R
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A
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R
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A
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F
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F
L
L
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M
E
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I
A
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A
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RDI
K
---
D
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L
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R
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---
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--------------
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---------
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-------
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----------------------------------------