@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y0U1: (2018-01-22 )
MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRIKGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNLCTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFYAYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFIAIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR
Atome Classification :
(20 SA)
-------------------.........--10...----.....20........30........40...--.....50..-.-.....60.......---.70.........80....-..-----..90..-......100.......110----......---.120.......130...-..---------..140..--.....150....-...160..---.....------------170..--.....180.......190.......200---........210......---.220......--------.230........240.......250-----------.......260....-------...270------.......280.......290........300....--...310.......320--------------........--------.330........340--....------...350-.........360..-----------------------.....370......---.380.......390.......400------.........410....--...420.......430..--.....440.......450...--....460...--.--...470.....-----.-.480........490.......500...-....510.......520...-....530...--....540..---------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------MKI
N
K
K
V
V
I
--
L
S
G
L
I
----
I
V
S
S
I
Y
S
F
I
FFKNT
Q
S
I
Y
TTGD
L
S
F
H
L
S
R
I--KG
L
S
T
I
FTS-P-INYETF
N
Y
T
GY
G
V
N
---
Y
F
-
Y
P
F
L
T
F
F
P
A
V
M
L
Y
W
M
-
T
K
-----
N
L
I
V
S
Y
-
I
I
Y
V
W
L
L
N
L
C
T
T
L
V
A
Y
H
Y
G
----
E
R
F
L
K
Q
---
K
K
A
A
F
L
F
S
C
L
Y
I
F
S
AY
R
-
T
V
---------
D
I
Y
Y
R
S
A
--
I
A
E
A
I
A
I
T
L
V
I
P
-
V
L
F
Y
A
Y
Q
I
---ISGKE------------EKYP
S
--
V
K
L
A
L
S
M
S
L
L
V
Y
S
H
V
L
S
T
L
M
S
T
A
L
I
I
I
----
F
I
F
I
R
L
V
S
KGFKN
A
D
F
I
---
A
I
F
K
K
L
F
S
AA--------G
M
-
T
L
V
L
T
S
A
F
W
Y
P
M
F
E
Q
M
L
Y
Q
KIN-----------KPS
V
T
N
L
Y
A
H
A
S
N
V
-------
F
D
S
L
T
E
------
A
MNNDL
T
T
Y
S
M
G
L
V
G
L
L
S
L
-
C
I
P
L
I
L
F
K
K
L
TN
I
E
K
--
K
I
Y
Y
G
T
C
L
T
W
L
A
T
T----------------SL
V
P
W
Y
L
L--------QN-T
P
A
K
L
L
Q
F
P
W
R
I
--
L
S
L
Q
------
I
I
F
S
---
S
L
I
L
T
M
I
F
FKNRRY-----------------------
N
K
T
R
E
L
F
Y
L
F
M
T
V
L
---
L
L
I
T
L
T
VSSKKNF
N
Q
K
I
ISQP
G
--------
H
I
V
V
NKET
V
E
A
Y
TTKG--
M
D
Y
F
L
YDYS
P
I
ASLEN
K
E
--
H
I
I
K
H
E
A
KIGS
Q
W
VNLPYKTT--G
S
S
I
I
Y
R
VTN--E--KS
Q
V
I
T
L
P
V
Y
A
-----Y-LGT-
N
V
E
INH
Q
P
V
K
E
QVNAN
G
L
V
Q
I
SGV-K
G
V
A
D
I
K
V
ST
S
Y
T
V
T
T
I
I
S
Y
-
L
V
T
L
T
A
Y
L
C
L
--
F
F
K
I
V
FHKR---------
19
Fugue
69.99
18%
-17
- C3 -
-
4R1D
-
?
A:
[45-561]
QTA
P
L
P
V
I
F
I
P
G
IMG
T
N
L
R
N
K
A
D
K
S
E
V
W
RP
P
N
G
L
W
PMDD
L
F
A
S
I
G
A
L
W
T
W
A
W
R
G
P
K
A
R
Q
E
L
L
K
A
E
Q
V
E
V
D
D
Q
G
T
I
D
V
G
Q
S
-
G
-
L
S
E
E
A
A
R
L
R
G
W
G
K
V
---
M
----
R
S
A
Y
N
P
V
M
G
L
M
E
R
-
R
L
-----
D
N
I
V
S
R
R
E
L
Q
A
W
W
N
D
E
A
L
S
P
P
G
D
Q
-
G
----
E
E
Q
G
K
V
GPI
D
E
E
E
L
L
R
A
S
R
Y
Q
F
D
V
W
C
-
A
G
---------
Y
N
W
L
Q
S
N
--
R
Q
S
A
L
D
V
R
D
Y
I
E
N
T
V
L
P
F
Y
Q
K
---
E
C
G
-----------------
L
D
--
P
E
Q
M
R
R
M
K
V
I
L
V
T
H
S
M
G
G
L
V
A
R
A
L
T
Q
L
----
H
G
Y
E
R
----------
V
L
---
G
V
V
H
G
V
Q
P
A
T
--------
G
S
S
T
I
Y
H
H
M
R
C
G
Y
E
G
I
A
Q
V
V
L
G
R
---------------
N
A
G
E
V
T
A
I
V
A
N
S
-------
A
G
A
L
E
L
------
A
P
S
A
E
---
Y
R
E
G
-
R
P
W
L
F
L
-
C
D
A
Q
--
G
Q
V
L
K
D
I
D
G
--
K
P
-------------------------------
R
A
Y
P
Q
--------
N
Q
-
D
P
Y
E
E
I
Y
K
N
T
T
W
--
Y
G
L
V
------
P
E
Q
N
---
S
Q
Y
L
D
M
S
D
K
K
E
G
L
R
-----------------------
V
G
P
R
D
N
F
E
D
L
I
D
S
I
---
A
N
F
H
G
E
L
S
A
A
-
G
Y
H
S
E
T
Y
A
H
Y
G
A
D
DSRHSW
R
D
L
I
W
K
G
D
P
T
P
L
E
T
P
G
--
A
T
L
N
D
D
E
N
G
T
Y
N
S
W
F
R
R
G
L
P
T
I
V
Q
G
P
L
E
T
G
N
-----
P
L
D
A
S
--
G
S
G
G
D
E
T
V
P
T
--
D
--
S
G
Q
A
P
A
L
A
-----------
G
V
-
K
A
S
F
R
H
----------------
G
S
-
K
G
K
G
Q
A
N
T
K
R
G
Y
E
H
Q
E
S
Y
N
D
-
A
R
A
Q
W
A
A
L
Y
G
--
V
I
K
I
T
Q
L
A
D
W--------
12
Fugue
69.17
14%
-114
- C3 -
-
5EZM
24
?
A:
[28-578]
-------------------
S
A
A
T
G
W
V
V
L
--
F
V
A
V
A
----
L
V
V
W
F
V
S
L
D
M
R
H
L
V
G
P
---------
D
E
G
R
Y
--
A
E
I
S
R
E
M
F
A
-
S
-
G
D
W
V
T
I
R
Y
N
A
--
L
K
---
Y
F
E
K
P
P
F
H
M
W
V
T
V
V
G
Y
E
L
-
F
G
-----
L
G
E
W
Q
A
-
R
L
A
V
A
L
S
G
L
L
G
I
G
V
S
M
M
A
A
----
R
R
W
F
G
A
---
R
A
A
A
F
T
G
L
A
L
L
A
A
P
M
W
S
-
V
A
---------
A
H
F
N
T
L
D
--
M
T
L
A
G
V
M
S
C
V
L
A
-
F
M
L
M
G
Q
H
P
DAS
V
A
A
R
R
------------
G
W
M
V
A
--
C
W
A
A
M
G
V
A
I
L
T
K
G
L
V
G
I
A
L
P
G
L
V
L
V
V
Y
----
T
L
V
T
R
--
D
W
G
L
W
R
R
L
H
L
---
A
L
G
V
V
V
M
L
V
I
--------
T
V
-
P
W
F
Y
L
V
S
V
R
N
P
E
F
P
N
F
F
F
I
H
E
H
WQRRSGSVFYF
L
P
L
V
I
G
G
F
L
P
W
A
G
I
-------
F
P
K
L
W
T
------
A
M
R
A
R
F
R
--
P
A
L
M
A
G
I
W
A
I
-
A
I
F
V
F
F
S
-----
I
S
R
--
S
K
L
P
G
Y
I
V
P
V
I
P
A
L
----------------
G
I
L
A
G
V
A
L
--------
D
R
-
L
S
P
R
--
S
W
G
K
Q
L
--
I
G
M
A
------
I
V
A
A
---
C
G
L
L
A
S
P
V
V
A
T
L
N
A
-----------------------
N
H
I
P
N
S
F
Y
R
A
Y
A
V
W
---
V
A
V
A
F
V
V
M
L
L
G
I
A
V
A
R
L
L
L
R
R
G
---------------
V
L
P
S
V
A
V
Y
A
--
M
G
M
Y
L
G
F
T
V
A
L
L
G
----
H
--
E
T
V
G
R
P
A
S
G
A
D
I
A
P
Q
I
A
Q
K
L
T
--
P
E
M
P
L
Y
G
V
-------
Q
M
L
D
H
T
L
P
F
Y
L
RHPLM
M
-
V
G
Q
-
A
D
E
L
T
F
G
A
T
V
E
P
Q
R
V
V
P
D
V
D
S
F
T
K
-
L
W
K
N
G
Q
P
A
M
A
V
M
S
P
D
T
Y
L
A
L
-
A
P
T
L
S
M
Y
V
V
A
RD
W
R
R
V
V
V
A
N
V
ASLAGPQ--
21
Fugue
53.64
14%
-34
- C1 -
-
2Q06
-
?
A:
[22-496]
-----------------------
A
T
E
I
R
--
A
S
V
G
R
----
M
V
G
G
I
G
R
F
Y
I
Q
M
C
T
E
---------
L
K
L
S
D
Q
--
E
G
--
R
L
I
Q
N
-
S
-
I
T
I
E
R
M
V
L
S
A
F
D
E
R
RNR
Y
K
-
D
P
K
K
T
G
G
P
---
I
Y
R
R
-
R
D
-----
G
K
W
V
R
E
-
L
I
L
Y
D
K
E
E
I
R
R
I
W
R
Q
A
N
N
G
----
E
---------
D
A
T
A
G
L
T
H
M
M
I
W
H
S
N
L
-
N
D
---------
A
T
Y
Q
R
-----
T
R
A
L
V
R
T
G
M
D
P
-
R
M
C
S
L
M
Q
---------------------------------
G
S
T
L
P
R
R
S
G
A
A
G
A
A
I
K
G
V
G
T
M
V
----
M
E
L
I
R
M
I
K
R
G
I
N
D
R
N
F
W
RGE
N
G
R
R
T
R
I
A
Y
E
--------
R
M
-
C
N
I
L
K
G
K
F
-
Q
T
A
A
Q
K
A
M
M
D
Q
V
R
-----------
E
S
R
----
N
P
G
N
A
E
I
-------
E
D
L
I
F
L
------
A
R
S
A
L
I
L
R
G
S
I
A
H
K
S
C
L
P
A
-
C
V
Y
G
L
A
V
A
S
G
Y
D
F
E
R
--
E
G
Y
--------
S
L
V
----------------
G
I
D
P
F
R
L
L
--------
Q
N
-
S
Q
-------------------------------
V
F
S
L
I
R
P
N
E
N
P
A
-----------------------
H
K
S
Q
L
V
W
M
A
C
H
S
A
A
FED
L
R
V
S
S
F
I
R
G
T
R
V
I
P
R
G
Q
L
S
T
R
G
--------
V
Q
I
A
S
N
E
N
V
E
A
M
D
S
S
T
--
L
E
L
R
S
R
Y
W
A
I
R
T
R
S
G
G
N
T
--
N
--
Q
Q
R
A
S
A
G
Q
I
S
V
Q
P
T
F
S
V
Q
--
R
N
------
L
P
--
F
--
E
R
A
T
I
M
A
A
F
K
G
-----
N
-
T
E
G
-
R
T
S
D
M
R
T
E
I
I
R
M
M
E
S
A
R
P
E
D
V
S
F
--
Q
G
R
G
V
F
E
L
S
D
E
K
A
T
N
P
I
V
P
S
-
F
-
D
M
S
N
E
G
S
Y
--
F
F
G
D
N
A
E
E
Y
---------
18
Fugue
49.12
16%
-88
- C3 -
-
5DA0
2
?
A:
[14-484]
---------------QREW
F
A
N
P
R
K
D
V
L
--
A
G
I
V
V
----
A
L
A
L
I
P
E
A
I
A
F
S
I
I
A
G
V
--
D
P
Q
V
G
L
Y
A
S
F
I
--
I
A
L
I
T
A
F
L
G
---------
G
R
P
G
------------
M
I
S
A
A
T
G
A
M
A
L
L
M
-
T
G
-----
L
V
K
D
H
G
-
I
Q
Y
L
F
A
A
T
V
L
T
G
V
L
Q
V
V
F
G
W
A
KL
A
R
Y
L
K
F
---
V
P
R
S
V
M
V
G
F
V
N
A
L
A
I
L
I
-
F
M
A
Q
LPQFVGA
N
W
Q
M
Y
A
M
--
V
A
A
G
L
A
I
I
Y
L
L
P
-
L
V
F
K
A
M
--------------------------
P
--
S
A
L
V
A
I
V
V
L
T
V
V
A
V
V
T
G
A
D
V
K
T
V
G
D
M
G
----
T
L
P
T
A
L
P
H
F
Q
F
P
Q
V
P
L
T
---
F
E
T
L
A
I
I
F
P
V
--------
A
L
-
T
L
S
L
V
G
L
L
E
S
L
L
T
A
Q
L
I
D
E
R
T
D
-----------
T
T
S
--------
D
K
N
-------
V
E
S
R
G
Q
------
G
V
A
N
I
V
T
G
F
F
G
G
M
A
G
C
--------------------------------
A
M
I
----------------
G
Q
S
M
I
N
V
T
--------
S
G
-
G
R
G
R
L
S
T
F
V
A
G
A
--
F
L
M
V
------
L
I
L
A
------------------------------------------
L
Q
P
L
L
V
Q
I
P
M
A
A
---
L
V
A
V
M
M
V
V
A
I
S
T
F
D
W
G
S
L
R
F
P
-------------
K
G
E
T
V
V
M
L
A
T
V
A
--
V
T
V
F
T
H
D
L
S
L
G
V
L
I
G
V
V
L
--
S
A
L
F
F
A
R
K
V
S
Q
L
S
Q
V
T
P
V
D
E
V
--
D
G
T
R
T
Y
R
V
R
G
-------
Q
L
F
F
V
S
T
H
D
-----
F
-
L
H
Q
F
D
F
T
H
P
A
R
R
V
V
I
D
L
S
D
A
H
F
W
D
G
S
A
V
-
G
A
L
D
K
V
M
L
K
F
M
R
Q
G
T
S
V
E
L
R
G
L
N
A
A
S
A
T
L
V
E
--
R
L
----------------
16
Fugue
47.80
14%
-129
- C3 -
-
4IKW
13
?
A:
[3-494]
-------------------------------------------------
S
I
D
K
Q
Q
I
A
A
S
V
P
Q
R
G
F
F
G
H
P
--
K
G
L
F
T
L
F
F
T
-
E
-
F
-
W
E
R
F
S
Y
Y
G
M
R
A
I
---
L
V
-
Y
Y
M
Y
Y
E
V
S
K
G
G
L
G
-
L
-
D
E
-----
H
L
A
L
A
I
-
M
S
I
Y
G
A
L
V
Y
M
S
G
I
I
G
G
W
L
A
----
D
R
V
F
G
T
---
S
R
A
V
F
-
Y
G
G
L
L
I
M
A
G
H
I
-
A
L
---------
A
I
P
G
G
V
A
--
A
L
F
V
S
M
A
L
I
V
L
G
-
T
G
L
L
K
P
N
V
---
S
S
I
V
G
------------
D
M
Y
K
P
GD
D
R
R
D
A
G
F
S
I
F
Y
M
G
I
N
L
G
A
F
L
A
P
L
V
V
G
T
----
A
G
M
K
Y
N
F
H
L
G
F
G
L
A
A
V
G
---
M
F
L
G
L
V
V
F
V
A
--------
T
R
-
K
K
N
L
G
L
A
G
T
Y
V
P
N
P
L
T
P
A
E
K
K
K
-----------
A
A
A
I
M
A
V
G
A
V
V
I
A
V
-------
L
L
A
I
L
I
------
P
N
G
W
F
T
V
E
T
F
I
S
L
V
G
I
L
G
I
-
I
I
P
I
I
Y
F
V
V
M
Y
R
S
P
K
TT
A
E
E
R
S
R
V
I
A
Y
I
P
L
F
----------------
V
A
S
A
M
F
W
A
--------
I
Q
-
E
Q
G
S
T
I
L
A
N
Y
A
D
--
K
R
T
Q
------
L
D
V
A
---
G
I
H
L
S
------------------------------------
P
A
W
F
Q
S
L
N
P
L
---
F
I
I
I
L
A
P
V
F
A
W
M
W
V
K
L
G
K
R
Q
P
----------------
T
I
P
Q
K
F
A
L
G
--
L
L
F
A
G
L
S
F
I
V
I
L
V
P
G
H
L
S
--
G
----
G
G
L
V
H
P
I
W
L
V
L
S
Y
F
I
V
V
L
G
E
L
C
L
S
P
V
G
L
--
S
--
A
T
T
K
L
A
P
A
A
F
S
-----
A
-
Q
T
M
-
S
L
W
F
L
S
N
A
A
A
Q
A
I
N
A
Q
L
V
R
F
----------------
Y
T
P
E
N
E
T
A
Y
-
F
G
T
I
G
G
A
A
L
V
--
L
G
L
I
L
L
A
I
A
P
R
I
G
R
L
MKG
8
HHSearch
44.58
13%
-182
- C4 -
-
5EZM
8
?
A:
[87-226]
-----------------------------------------------------------------------------------------------------
E
-
K
P
P
F
H
M
W
V
T
V
V
G
Y
E
L
-
F
G
-----
L
G
E
W
Q
A
-
R
L
A
V
A
L
S
G
L
L
G
I
G
V
S
M
M
A
A
----
R
R
W
F
G
A
---
R
-
A
A
A
F
T
G
L
A
L
L
A
A
P
M
W
-
S
V
---------
A
--
A
H
F
N
--
T
L
D
M
T
L
A
G
V
M
S
C
-
V
L
A
F
M
L
M
G
---
Q
H
P
D
A
S
V
A
A
R
-------
R
G
W
-
M
--
V
A
C
W
A
A
M
G
V
A
I
L
T
K
G
L
V
G
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
HHSearch
43.59
13%
-180
- C4 -
-
5F15
8
?
A:
[87-221]
-----------------------------------------------------------------------------------------------------
E
-
K
P
P
F
H
M
W
V
T
V
V
G
Y
E
L
-
F
G
-----
L
G
E
W
Q
A
-
R
L
A
V
A
L
S
G
L
L
G
I
G
V
S
M
M
A
A
----
R
R
W
F
G
A
---
R
-
A
A
A
F
T
G
L
A
L
L
A
A
P
M
W
-
S
V
---------
A
--
A
H
F
N
--
T
L
D
M
T
L
A
G
V
M
S
C
-
V
L
A
F
M
L
M
G
---
Q
H
P
D
A
S
V
A
A
R
-------
R
G
W
-
M
--
V
A
C
W
A
A
M
G
V
A
I
L
T
K
G
L
V
G
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
HHSearch
43.32
11%
-159
- C4 -
-
3WAJ
-
?
A:
[44-278]
---------------------------------------------------------
G
G
N
D
P
W
Y
Y
Y
R
L
I
--
E
N
T
I
H
N
F
P
H
R
I
W
F
D
P
F
T
Y
Y
P
Y
G
S
Y
T
-----
H
-
F
G
P
F
L
V
Y
L
G
S
I
A
G
I
I
-
F
S
ATSG
E
S
L
R
A
V
L
-
A
F
I
P
A
I
G
G
V
L
A
I
L
P
V
Y
L
L
T
----
R
E
V
F
-
D
---
K
R
A
A
V
I
A
A
F
L
I
A
I
V
P
G
Q
F
L
Q
---------
R
S
I
L
G
F
N
--
D
H
H
I
W
E
A
F
W
Q
V
S
-
A
L
G
T
F
L
L
A
---
Y
N
R
W
K
GHDLT
A
R
Q
----
M
A
Y
-
P
--
V
I
A
G
I
T
I
G
L
Y
V
L
S
W
G
A
G
F
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
HHSearch
42.89
11%
-167
- C4 -
-
3WAK
-
?
A:
[44-221]
---------------------------------------------------------
G
G
N
D
P
W
Y
Y
Y
R
L
I
--
E
N
T
I
H
N
F
P
H
R
I
W
F
D
P
F
T
Y
Y
P
Y
G
S
Y
T
-----
H
-
F
G
P
F
L
V
Y
L
G
S
I
A
G
I
I
-
F
S
ATSG
E
S
L
R
A
V
L
-
A
F
I
P
A
I
G
G
V
L
A
I
L
P
V
Y
L
L
T
----
R
E
V
F
-
D
---
K
R
A
A
V
I
A
A
F
L
I
A
I
V
P
G
Q
F
L
Q
---------
R
S
I
L
G
F
N
--
D
H
H
I
W
E
A
F
W
Q
V
S
-
A
L
G
T
F
L
L
A
---
Y
N
R
W
K
GHDLSHNLT
A
R
Q
M
A
Y
-
P
--
V
I
A
G
I
T
I
G
L
Y
V
L
S
W
G
A
G
F
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
39.02
17%
-142
- C7 -
-
5FU5
-
?
A:
[72-100]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
-
T
A
K
V
D
G
N
K
V
T
---
A
S
N
G
I
I
T
V
D
L
A
-
Q
G
A
H
T
I
---------------------------------------------
13
Fugue
35.45
13%
-49
* C4 *
-
3MVC
1
GLOB6_CAEEL
A:
[1-161]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
L
T
Q
P
Q
I
---
L
F
V
R
K
T
W
N
H
A
R
N
QGALE
P
A
I
-
S
I
F
R
N
S
F
F
K
N
P
E
I
R
Q
M
I
M
F
G
T
K
-----------
N
E
G
H
E
R
L
K
K
H
A
Q
L
F
-------
T
V
L
M
D
D
------
L
I
A
N
--------------
L
-
D
S
P
S
A
T
V
A
G
L
R
E
A
G
E
--
K
H
V
W
P
T
R
N
Q
Y
G
C
P
F
----------------
H
A
H
L
L
D
Q
F
--------
A
T
-
A
M
I
E
R
T
L
E
W
D
R
T
--
E
T
T
Q
------
R
G
W
T
---
K
I
V
L
F
V
T
E
Q
L
K
E
G
F
-----------------------
Q
D
E
Q
K
R
A
R
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
Fugue
34.50
23%
-35
* C5 *
-
4FYP
-
VSP1_ARATH
A:
[34-261]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
L
--
S
I
N
Y
P
N
C
R
S
W
H
L
G
V
E
T
SNIINFDTVPANC
K
A
Y
V
E
D
Y
L
I
TSK
Q
Y
Q
Y
D
S
K
-
T
V
N
K
E
A
Y
F
Y
A
K
G
--
L
A
L
K
NDTV
N
V
W
I
F
D
L
DD
T
L
L
S
S
I
P
Y
Y
A
K
Y
G
Y
GT
E
N
T
A
PG
A
Y
W
S
W
L
E
S
G
E
S
T
P
G
L
P
E
T
L
H
L
Y
E
N
L
L
E
L
G
---
I
E
P
I
I
I
S
D
R
W
K
K
L
S
E
V
T
V
E
N
L
K
--------
A
V
G
V
T
K
W
K
H
L
I
L
K
P
N
G
SK
L
T
Q
V
V
Y
K
S
K
V
R
N
S
L
V
K
K
G
--
Y
N
I
V
--
G
N
I
G
D
Q
W
A
D
L
V
E
D
T
P
--
G
----------------
R
V
F
K
L
P
N
P
L
-----
Y
-
Y
V
P
-
S
L
E
H
H
H
H
---------------------------------------------------------------------
1
PsiBlast_PDB
34.19
28%
-108
* C6 *
-
5SY1
-
?
A:
[151-235]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
G
S
L
L
S
W
T
H
F
G
I
L
V
W
Q
K
V
D
-----------
C
P
K
T
P
Q
I
Y
K
Y
Y
A
-
L
-------
F
G
S
L
P
Q
----------------
I
A
C
L
A
F
L
S
F
-
Q
Y
P
L
L
L
F
K
G
L
Q
N
T
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
33.58
11%
10
* C7 *
-
5MQO
-
?
A:
[513-580]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
N
V
R
V
T
L
N
K
VP
R
KA
G
A
F
S
L
F
F
R
I
P
E
-----
W
C
G
K
A
-
A
L
T
V
N
G
Q
P
V
S
M
N
A
K
A
N
T
Y
A
E
V
N
R
T
W
K
K
G
D
V
V
E
L
V
M
D
M
P
--------------------------------------
15
Fugue
33.30
17%
-81
- C5 -
-
2AXP
-
YORR_BACSU
A:
[2-173]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
I
I
L
E
G
P
D
C
C
F
K
S
T
V
A
A
K
L
S
K
E
L
K
Y
---
P
I
I
K
--------------
G
S
-
S
F
E
L
A
K
S
G
N
E
K
L
F
E
H
F
N
K
L
A
D
E
-----------
D
N
V
I
I
D
R
F
V
Y
S
N
L
V
YAKKFKD
Y
S
I
L
T
E
------
R
Q
L
R
F
I
E
D
K
I
K
A
K
A
K
V
V
Y
L
H
A
D
P
S
V
I
K
K
R
L
R
V
R
G
D
--
E
Y
I
E
G
K
-----
D
I
D
----------------
S
I
L
E
L
Y
R
---------
E
V
M
S
N
A
G
L
H
T
Y
S
W
D
T
GQ
W
S
S
D
------
E
I
A
K
---
D
I
I
F
L
V
E
L
E
H
H
H
H
H
-----------------------
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
32.64
9%
-166
- C4 -
-
3RCE
-
PGLB_CAMLR
A:
[53-227]
---------------------------------------------------------
T
T
N
D
G
Y
A
F
A
E
G
A
--
R
D
M
I
A
G
F
H
----
Q
-
P
N
--------
D
L
---
S
Y
-
F
G
S
S
L
S
T
L
T
Y
W
L
Y
S
I
L
P
F
-----
S
F
E
S
I
I
-
L
Y
M
S
T
F
F
A
S
L
I
V
V
P
I
I
L
I
A
----
R
E
Y
K
L
----
T
T
Y
G
F
I
A
A
L
L
G
S
I
A
N
S
Y
-
Y
N
---------
R
T
--
M
S
G
YY
D
T
D
M
L
V
L
V
L
P
M
L
-
I
L
L
T
F
I
R
L
---
T
I
N
K
D
------------
I
F
T
-
L
--
L
L
S
P
I
F
I
M
I
Y
L
W
W
Y
P
S
S
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
Fugue
28.23
29%
-106
- C2 -
-
1UHE
1
?
B:
[1-24]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
F
E
M
L
Y
S
K
I
H
-----------
R
A
T
I
T
D
A
N
L
N
Y
I
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
27.23
30%
-116
- C6 -
-
3E22
1
TBA1C_BOVIN
A:
[219-280]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
-----------
R
P
T
Y
T
N
L
N
R
L
M
S
Q
I
-------
V
S
S
I
T
A
SLRFDG
A
L
N
V
D
L
T
E
F
Q
T
N
L
V
P
Y
P
R
I
-
H
F
P
L
A
T
Y
A
P
V
I
S
A
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
24.16
30%
-135
- C6 -
-
3DU7
1
TBA1C_BOVIN
A:
[219-280]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
-----------
R
P
T
Y
T
N
L
N
R
L
M
S
Q
I
-------
V
S
S
I
T
A
SLRFDG
A
L
N
V
D
L
T
E
F
Q
T
N
L
V
P
Y
P
R
I
-
H
F
P
L
A
T
Y
A
P
V
I
S
A
E
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
12.84
31%
165
* C3 *
-
2GWW
-
B:
[9-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
N
I
Y
K
A
A
K
D
V
-------
T
T
S
L
S
K
------
V
L
K
N
I
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------