@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y193: (2018-01-24 )
MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNITLGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMTKSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADLRRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD
Atome Classification :
(26 SA)
----------.........10........20........30........40........50....-.-.--..60-........70........80........90-.--.-.--.-.....100.......110.......120.....---..130-----.---.......140.......150.....-..160---.----......170.......180.......190....-...200-.......210....--
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------MKI
A
P
S
I
L
S
A
D
F
A
N
L
Q
R
D
I
E
L
V
E
KGGA
D
Y
I
H
V
D
VMDGQFVPNITL
G
P
N
I
V
Q
A
I
R
P
-
V
-T--KL
P
L
-
D
V
H
L
M
I
VDPENY
I
P
A
F
A
KAGA
D
I
I
T
V
H
V
E--A--
T
-
P
--
H
-
I
H
R
A
L
Q
M
T
K
SLG
V
K
A
G
V
V
INPGT
P
V
S
M
I
K
H
V
LP---LA
D
Q
------
V
---
L
V
M
T
VNPGFG
G
Q
S
F
I
E
E
T
V
E
K
I
T
E
L
-
A
D
L
R
R---E----NN
W
T
Y
A
I
EVDGGIVP
E
T
A
K
I
C
K
DAGA
D
V
F
V
AG
S
-
Y
I
YGAE-NP
V
G
Q
I
E
R
L
K
E
ALD--
84
HHSearch
94.23
55%
0
- C- -
-
2FLI
-
?
J:
[4-218]
----------
L
K
I
A
P
S
I
L
A
A
D
Y
A
N
F
A
S
E
L
A
R
I
E
E
T
D
A
E
Y
V
H
I
D
I
M
D
G
Q
F
V
P
N
I
S
F
G
A
D
V
V
A
S
M
R
K
-
H
-
S
--
K
L
V
F
-
D
C
H
L
M
V
V
D
P
E
R
Y
V
E
A
F
A
Q
A
G
A
D
I
M
T
I
H
T
E
--
S
--
T
-
R
--
H
-
I
H
G
A
L
Q
K
I
K
A
A
G
M
K
A
G
V
V
I
N
P
G
T
P
A
T
A
L
E
P
L
L
D
---
L
V
D
Q
------
V
---
L
I
M
T
V
N
P
G
F
G
G
Q
A
F
I
P
E
C
L
E
K
V
A
T
V
-
A
K
W
R
D
---
E
----
K
G
L
S
F
D
I
E
V
D
G
G
V
D
N
K
T
I
R
A
C
Y
E
A
G
A
N
V
F
V
A
G
S
-
Y
L
F
K
A
S
-
D
L
V
S
Q
V
Q
T
L
R
T
A
L
---
83
HHSearch
94.23
55%
0
- C- -
-
2FLI
-
?
C:
[4-218]
----------
L
K
I
A
P
S
I
L
A
A
D
Y
A
N
F
A
S
E
L
A
R
I
E
E
T
D
A
E
Y
V
H
I
D
I
M
D
G
Q
F
V
P
N
I
S
F
G
A
D
V
V
A
S
M
R
K
-
H
-
S
--
K
L
V
F
-
D
C
H
L
M
V
V
D
P
E
R
Y
V
E
A
F
A
Q
A
G
A
D
I
M
T
I
H
T
E
--
S
--
T
-
R
--
H
-
I
H
G
A
L
Q
K
I
K
A
A
G
M
K
A
G
V
V
I
N
P
G
T
P
A
T
A
L
E
P
L
L
D
---
L
V
D
Q
------
V
---
L
I
M
T
V
N
P
G
F
G
G
Q
A
F
I
P
E
C
L
E
K
V
A
T
V
-
A
K
W
R
D
---
E
----
K
G
L
S
F
D
I
E
V
D
G
G
V
D
N
K
T
I
R
A
C
Y
E
A
G
A
N
V
F
V
A
G
S
-
Y
L
F
K
A
S
-
D
L
V
S
Q
V
Q
T
L
R
T
A
L
---
21
PsiBlast_CBE
93.72
54%
0
- C- -
-
2FLI
10
?
L:
[4-219]
----------
L
K
I
A
P
S
I
L
A
A
D
Y
A
N
F
A
S
E
L
A
R
I
E
E
T
D
A
E
Y
V
H
I
D
I
M
D
G
Q
F
V
P
N
I
S
F
G
A
D
V
V
A
S
M
R
K
-
H
-
S
--
K
L
V
F
-
D
C
H
L
M
V
V
D
P
E
R
Y
V
E
A
F
A
Q
A
G
A
D
I
M
T
I
H
T
E
--
S
--
T
-
R
--
H
-
I
H
G
A
L
Q
K
I
K
A
A
G
M
K
A
G
V
V
I
N
P
G
T
P
A
T
A
L
E
P
L
L
D
---
L
V
D
Q
------
V
---
L
I
M
T
V
N
P
G
F
G
G
Q
A
F
I
P
E
C
L
E
K
V
A
T
V
-
A
K
W
R
D
---
E
----
K
G
L
S
F
D
I
E
V
D
G
G
V
D
N
K
T
I
R
A
C
Y
E
A
G
A
N
V
F
V
A
G
S
-
Y
L
F
K
A
S
-
D
L
V
S
Q
V
Q
T
L
R
T
A
L
N
--
1
PsiBlast_PDB
93.72
54%
0
- C- -
-
2FLI
1
?
A:
[4-219]
----------
L
K
I
A
P
S
I
L
A
A
D
Y
A
N
F
A
S
E
L
A
R
I
E
E
T
D
A
E
Y
V
H
I
D
I
M
D
G
Q
F
V
P
N
I
S
F
G
A
D
V
V
A
S
M
R
K
-
H
-
S
--
K
L
V
F
-
D
C
H
L
M
V
V
D
P
E
R
Y
V
E
A
F
A
Q
A
G
A
D
I
M
T
I
H
T
E
--
S
--
T
-
R
--
H
-
I
H
G
A
L
Q
K
I
K
A
A
G
M
K
A
G
V
V
I
N
P
G
T
P
A
T
A
L
E
P
L
L
D
---
L
V
D
Q
------
V
---
L
I
M
T
V
N
P
G
F
G
G
Q
A
F
I
P
E
C
L
E
K
V
A
T
V
-
A
K
W
R
D
---
E
----
K
G
L
S
F
D
I
E
V
D
G
G
V
D
N
K
T
I
R
A
C
Y
E
A
G
A
N
V
F
V
A
G
S
-
Y
L
F
K
A
S
-
D
L
V
S
Q
V
Q
T
L
R
T
A
L
N
--
31
PsiBlast_CBE
93.24
54%
0
- C- -
-
2FLI
1
?
B:
[4-218]
----------
L
K
I
A
P
S
I
L
A
A
D
Y
A
N
F
A
S
E
L
A
R
I
E
E
T
D
A
E
Y
V
H
I
D
I
M
D
G
Q
F
V
P
N
I
S
F
G
A
D
V
V
A
S
M
R
K
-
H
-
S
--
K
L
V
F
-
D
C
H
L
M
V
V
D
P
E
R
Y
V
E
A
F
A
Q
A
G
A
D
I
M
T
I
H
T
E
--
S
--
T
-
R
--
H
-
I
H
G
A
L
Q
K
I
K
A
A
G
M
K
A
G
V
V
I
N
P
G
T
P
A
T
A
L
E
P
L
L
D
---
L
V
D
Q
------
V
---
L
I
M
T
V
N
P
G
F
G
G
Q
A
F
I
P
E
C
L
E
K
V
A
T
V
-
A
K
W
R
D
---
E
----
K
G
L
S
F
D
I
E
V
D
G
G
V
D
N
K
T
I
R
A
C
Y
E
A
G
A
N
V
F
V
A
G
S
-
Y
L
F
K
A
S
-
D
L
V
S
Q
V
Q
T
L
R
T
A
L
---
79
HHSearch
84.11
49%
-139
- C4 -
-
5UMF
2
?
B:
[13-230]
-----------
R
I
A
P
S
I
L
S
A
D
F
A
R
L
G
E
E
V
A
N
V
I
A
A
G
A
D
L
I
H
F
D
V
M
D
N
H
Y
V
P
N
L
T
F
G
P
M
V
C
A
A
L
K
P
-
Y
-
A
--
S
V
P
I
-
D
V
H
L
M
V
E
P
V
D
D
L
I
Q
S
F
A
K
A
G
A
S
I
I
T
F
H
P
E
--
A
--
S
-
R
--
H
-
I
D
R
S
L
S
L
I
R
D
M
G
C
Q
A
G
L
V
L
N
P
A
T
P
V
Y
V
L
E
N
V
L
D
---
R
L
D
M
------
V
---
L
L
M
S
V
N
P
G
F
G
G
Q
S
F
I
P
H
T
L
E
K
I
R
Q
V
-
R
A
M
L
D
---
R
YEGK
S
G
R
R
I
A
I
E
V
D
G
G
I
K
T
D
N
I
A
A
V
A
R
A
G
A
D
T
F
V
A
G
S
-
A
I
F
G
K
P
-
D
Y
K
A
V
I
A
A
M
R
A
E
L
---
35
PsiBlast_CBE
83.32
48%
-134
- C4 -
-
5UMF
2
?
B:
[13-231]
-----------
R
I
A
P
S
I
L
S
A
D
F
A
R
L
G
E
E
V
A
N
V
I
A
A
G
A
D
L
I
H
F
D
V
M
D
N
H
Y
V
P
N
L
T
F
G
P
M
V
C
A
A
L
K
P
-
Y
-
A
--
S
V
P
I
-
D
V
H
L
M
V
E
P
V
D
D
L
I
Q
S
F
A
K
A
G
A
S
I
I
T
F
H
P
E
--
A
--
S
-
R
--
H
-
I
D
R
S
L
S
L
I
R
D
M
G
C
Q
A
G
L
V
L
N
P
A
T
P
V
Y
V
L
E
N
V
L
D
---
R
L
D
M
------
V
---
L
L
M
S
V
N
P
G
F
G
G
Q
S
F
I
P
H
T
L
E
K
I
R
Q
V
R
A
M
L
D
R
YEG
K
----
S
G
R
R
I
A
I
E
V
D
G
G
I
K
T
D
N
I
A
A
V
A
R
A
G
A
D
T
F
V
A
G
S
-
A
I
F
G
K
P
-
D
Y
K
A
V
I
A
A
M
R
A
E
L
E
--
78
HHSearch
83.08
49%
-138
- C4 -
-
5UMF
1
?
C:
[13-230]
-----------
R
I
A
P
S
I
L
S
A
D
F
A
R
L
G
E
E
V
A
N
V
I
A
A
G
A
D
L
I
H
F
D
V
M
D
N
H
Y
V
P
N
L
T
F
G
P
M
V
C
A
A
L
K
P
-
Y
-
A
--
S
V
P
I
-
D
V
H
L
M
V
E
P
V
D
D
L
I
Q
S
F
A
K
A
G
A
S
I
I
T
F
H
P
E
--
A
--
S
-
R
--
H
-
I
D
R
S
L
S
L
I
R
D
M
G
C
Q
A
G
L
V
L
N
P
A
T
P
V
Y
V
L
E
N
V
L
D
---
R
L
D
M
------
V
---
L
L
M
S
V
N
P
G
F
G
G
Q
S
F
I
P
H
T
L
E
K
I
R
Q
V
-
R
A
M
L
D
---
R
YEGK
S
G
R
R
I
A
I
E
V
D
G
G
I
K
T
D
N
I
A
A
V
A
R
A
G
A
D
T
F
V
A
G
S
-
A
I
F
G
K
P
-
D
Y
K
A
V
I
A
A
M
R
A
E
L
---
4
PsiBlast_PDB
82.88
48%
-134
- C4 -
-
5UMF
1
?
A:
[13-231]
-----------
R
I
A
P
S
I
L
S
A
D
F
A
R
L
G
E
E
V
A
N
V
I
A
A
G
A
D
L
I
H
F
D
V
M
D
N
H
Y
V
P
N
L
T
F
G
P
M
V
C
A
A
L
K
P
-
Y
-
A
--
S
V
P
I
-
D
V
H
L
M
V
E
P
V
D
D
L
I
Q
S
F
A
K
A
G
A
S
I
I
T
F
H
P
E
--
A
--
S
-
R
--
H
-
I
D
R
S
L
S
L
I
R
D
M
G
C
Q
A
G
L
V
L
N
P
A
T
P
V
Y
V
L
E
N
V
L
D
---
R
L
D
M
------
V
---
L
L
M
S
V
N
P
G
F
G
G
Q
S
F
I
P
H
T
L
E
K
I
R
Q
V
R
A
M
L
D
R
Y
E
G
K
----
S
G
R
R
I
A
I
E
V
D
G
G
I
K
T
D
N
I
A
A
V
A
R
A
G
A
D
T
F
V
A
G
S
-
A
I
F
G
K
P
-
D
Y
K
A
V
I
A
A
M
R
A
E
L
E
--
34
PsiBlast_CBE
82.60
48%
-134
- C4 -
-
5UMF
1
?
C:
[13-231]
-----------
R
I
A
P
S
I
L
S
A
D
F
A
R
L
G
E
E
V
A
N
V
I
A
A
G
A
D
L
I
H
F
D
V
M
D
N
H
Y
V
P
N
L
T
F
G
P
M
V
C
A
A
L
K
P
-
Y
-
A
--
S
V
P
I
-
D
V
H
L
M
V
E
P
V
D
D
L
I
Q
S
F
A
K
A
G
A
S
I
I
T
F
H
P
E
--
A
--
S
-
R
--
H
-
I
D
R
S
L
S
L
I
R
D
M
G
C
Q
A
G
L
V
L
N
P
A
T
P
V
Y
V
L
E
N
V
L
D
---
R
L
D
M
------
V
---
L
L
M
S
V
N
P
G
F
G
G
Q
S
F
I
P
H
T
L
E
K
I
R
Q
V
R
A
M
L
D
R
YEG
K
----
S
G
R
R
I
A
I
E
V
D
G
G
I
K
T
D
N
I
A
A
V
A
R
A
G
A
D
T
F
V
A
G
S
-
A
I
F
G
K
P
-
D
Y
K
A
V
I
A
A
M
R
A
E
L
E
--
87
HHSearch
80.66
54%
-66
- C4 -
-
1TQJ
-
RPE_SYNY3
D:
[5-221]
----------
I
V
V
A
P
S
I
L
S
A
D
F
S
R
L
G
E
E
I
K
A
V
D
E
A
G
A
D
W
I
H
V
D
V
M
D
G
R
F
V
P
N
I
T
I
G
P
L
I
V
D
A
I
R
P
-
L
-
T
--
K
K
T
L
-
D
V
H
L
M
I
V
E
P
E
K
Y
V
E
D
F
A
K
A
G
A
D
I
I
S
V
H
V
E
--
H
--
N
-
A
SP
H
-
L
H
R
T
L
C
Q
I
R
E
L
G
K
K
A
G
A
V
L
N
P
S
T
P
L
D
F
L
E
Y
V
L
P
---
V
C
D
L
------
I
---
L
I
M
S
V
N
-----
Q
S
F
I
P
E
V
L
P
K
I
R
A
L
-
R
Q
M
C
D
---
E
----
R
G
L
D
P
W
I
E
V
D
G
G
L
K
P
N
N
T
W
Q
V
L
E
A
G
A
N
A
I
V
A
G
S
-
A
V
F
N
A
P
-
N
Y
A
E
A
I
A
G
V
R
N
S
K
---
2
PsiBlast_PDB
80.43
53%
-61
- C4 -
-
1RPX
-
RPE_SOLTU
A:
[13-226]
------------
V
S
P
S
I
L
S
A
N
F
S
K
L
G
E
Q
V
K
A
I
E
Q
A
G
C
D
W
I
H
V
D
V
M
D
G
R
F
V
P
N
I
T
I
G
P
L
V
V
D
S
L
R
P
-
I
-
T
--
D
L
P
L
-
D
V
H
L
M
I
V
E
P
D
Q
R
V
P
D
F
I
K
A
G
A
D
I
V
S
V
H
C
E
QS
S
--
T
-
I
--
H
-
L
H
R
T
I
N
Q
I
K
S
L
G
A
K
A
G
V
V
L
N
P
G
T
P
L
T
A
I
E
Y
V
L
D
---
A
V
D
L
------
V
---
L
I
M
S
V
N
P
G
F
G
G
Q
S
F
I
E
S
Q
V
K
K
I
S
D
L
-
R
K
I
C
A
---
E
----
R
G
L
N
P
W
I
E
V
D
G
G
V
G
P
K
N
A
Y
K
V
I
E
A
G
A
N
A
L
V
A
G
S
-
A
V
F
G
A
P
-
D
Y
A
E
A
I
K
G
I
K
T
S
----
88
HHSearch
79.93
53%
-60
- C4 -
-
1RPX
-
RPE_SOLTU
B:
[11-227]
----------
I
I
V
S
P
S
I
L
S
A
N
F
S
K
L
G
E
Q
V
K
A
I
E
Q
A
G
C
D
W
I
H
V
D
V
M
D
G
R
F
V
P
N
I
T
I
G
P
L
V
V
D
S
L
R
P
-
I
-
T
--
D
L
P
L
-
D
V
H
L
M
I
V
E
P
D
Q
R
V
P
D
F
I
K
A
G
A
D
I
V
S
V
H
C
E
--
Q
--
S
S
T
I-
H
-
L
H
R
T
I
N
Q
I
K
S
L
G
A
K
A
G
V
V
L
N
P
G
T
P
L
T
A
I
E
Y
V
L
D
---
A
V
D
L
------
V
---
L
I
M
S
V
N
P
G
F
G
G
Q
S
F
I
E
S
Q
V
K
K
I
S
D
L
-
R
K
I
C
A
---
E
----
R
G
L
N
P
W
I
E
V
D
G
G
V
G
P
K
N
A
Y
K
V
I
E
A
G
A
N
A
L
V
A
G
S
-
A
V
F
G
A
P
-
D
Y
A
E
A
I
K
G
I
K
T
S
K
---
3
PsiBlast_PDB
79.33
57%
-80
- C4 -
-
1TQJ
-
RPE_SYNY3
A:
[7-209]
------------
V
A
P
S
I
L
S
A
D
F
S
R
L
G
E
E
I
K
A
V
D
E
A
G
A
D
W
I
H
V
D
V
M
D
G
R
F
V
P
N
I
T
I
G
P
L
I
V
D
A
I
R
P
-
L
-
T
--
K
K
T
L
-
D
V
H
L
M
I
V
E
P
E
K
Y
V
E
D
F
A
K
A
G
A
D
I
I
S
V
H
V
E
HN
A
--
S
-
P
--
H
-
L
H
R
T
L
C
Q
I
R
E
L
G
K
K
A
G
A
V
L
N
P
S
T
P
L
D
F
L
E
Y
V
L
P
---
V
C
D
L
------
I
---
L
I
M
S
V
N
P
----
Q
S
F
I
P
E
V
L
P
K
I
R
A
L
-
R
Q
M
C
D
---
E
----
R
G
L
D
P
W
I
E
V
D
G
G
L
K
P
N
N
T
W
Q
V
L
E
A
G
A
N
A
I
V
A
G
S
-
A
V
F
N
A
P
-
N
---------------
63
Fugue
75.91
52%
1
- C4 -
-
1RPX
-
RPE_SOLTU
A:
[1-230]
SRVDKFSKS
D
I
I
V
S
P
S
I
L
S
A
N
F
S
K
L
G
E
Q
V
K
A
I
E
Q
A
G
C
D
W
I
H
V
D
V
M
D
G
R
F
V
P
N
I
T
I
G
P
L
V
V
D
S
L
R
P
-
I
-
T
--
D
L
P
L
-
D
V
H
L
M
I
V
E
P
D
Q
R
V
P
D
F
I
K
A
G
A
D
I
V
S
V
H
C
E
--
Q
SS
T
-
I
--
H
-
L
H
R
T
I
N
Q
I
K
S
L
G
A
K
A
G
V
V
L
N
P
G
T
P
L
T
A
I
E
Y
V
L
D
---
A
V
D
L
------
V
---
L
I
M
S
V
N
P
G
F
G
G
Q
S
F
I
E
S
Q
V
K
K
I
S
D
L
-
R
K
I
C
A
---
E
----
R
G
L
N
P
W
I
E
V
D
G
G
V
G
P
K
N
A
Y
K
V
I
E
A
G
A
N
A
L
V
A
G
S
-
A
V
F
G
A
P
-
D
Y
A
E
A
I
K
G
I
K
T
S
K
R
P
E
81
HHSearch
75.12
44%
-72
- C4 -
-
1H1Z
-
RPE1_ORYSJ
A:
[7-221]
----------
A
K
I
A
P
S
M
L
S
S
D
F
A
N
L
A
A
E
A
D
R
M
V
R
L
G
A
D
W
L
H
M
D
I
M
D
G
H
F
V
P
N
L
T
I
G
A
P
V
I
Q
S
L
R
K
-
H
-
T
--
K
A
Y
L
-
D
C
H
L
M
V
T
N
P
S
D
Y
V
E
P
L
A
K
A
G
A
S
G
F
T
F
H
I
E
--
V
--
S
-
R
D-
N
-
W
Q
E
L
I
Q
S
I
K
A
K
G
M
R
P
G
V
S
L
R
P
G
T
P
V
E
E
V
F
P
L
V
E
AEN
P
V
E
L
------
V
---
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
P
E
M
M
E
K
V
R
A
L
-
R
K
K
-----------
Y
P
S
L
D
I
E
V
D
G
G
L
G
P
S
T
I
D
V
A
A
S
A
G
A
N
C
I
V
A
G
S
-
S
I
F
G
A
A
-
E
P
G
E
V
I
S
A
L
R
K
S
V
---
80
HHSearch
74.99
44%
-75
* C4 *
-
1H1Y
-
RPE1_ORYSJ
B:
[7-221]
----------
A
K
I
A
P
S
M
L
S
S
D
F
A
N
L
A
A
E
A
D
R
M
V
R
L
G
A
D
W
L
H
M
D
I
M
D
G
H
F
V
P
N
L
T
I
G
A
P
V
I
Q
S
L
R
K
-
H
-
T
--
K
A
Y
L
-
D
C
H
L
M
V
T
N
P
S
D
Y
V
E
P
L
A
K
A
G
A
S
G
F
T
F
H
I
E
--
V
--
S
-
R
D-
N
-
W
Q
E
L
I
Q
S
I
K
A
K
G
M
R
P
G
V
S
L
R
P
G
T
P
V
E
E
V
F
P
L
V
E
AEN
P
V
E
L
------
V
---
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
P
E
M
M
E
K
V
R
A
L
-
R
K
K
-----------
Y
P
S
L
D
I
E
V
D
G
G
L
G
P
S
T
I
D
V
A
A
S
A
G
A
N
C
I
V
A
G
S
-
S
I
F
G
A
A
-
E
P
G
E
V
I
S
A
L
R
K
S
V
---
6
PsiBlast_PDB
73.93
43%
-62
- C4 -
-
1H1Z
-
RPE1_ORYSJ
A:
[8-222]
-----------
K
I
A
P
S
M
L
S
S
D
F
A
N
L
A
A
E
A
D
R
M
V
R
L
G
A
D
W
L
H
M
D
I
M
D
G
H
F
V
P
N
L
T
I
G
A
P
V
I
Q
S
L
R
K
-
H
-
T
--
K
A
Y
L
-
D
C
H
L
M
V
T
N
P
S
D
Y
V
E
P
L
A
K
A
G
A
S
G
F
T
F
H
I
E
--
V
--
S
-
R
D-
N
-
W
Q
E
L
I
Q
S
I
K
A
K
G
M
R
P
G
V
S
L
R
P
G
T
P
V
---
E
E
V
F
P
---
L
V
E
A
ENPVE
L
V
---
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
P
E
M
M
E
K
V
R
A
L
-----
R
---
K
----
K
Y
P
S
L
D
I
E
V
D
G
G
L
G
P
S
T
I
D
V
A
A
S
A
G
A
N
C
I
V
A
G
S
-
S
I
F
G
A
A
-
E
P
G
E
V
I
S
A
L
R
K
S
V
E
--
7
PsiBlast_PDB
73.72
41%
-52
- C4 -
-
3INP
-
?
A:
[28-244]
----------
I
Q
I
N
P
S
I
L
S
A
D
L
A
R
L
G
D
D
V
K
A
V
L
A
A
G
A
D
N
I
H
F
D
V
M
D
N
H
Y
V
P
N
L
T
F
G
P
M
V
L
K
A
L
R
D
-
Y
G
I
--
T
A
G
M
-
D
V
H
L
M
V
K
P
V
D
A
L
I
E
S
F
A
K
A
G
A
T
S
I
V
F
H
P
E
--
A
--
S
-
E
--
H
-
I
D
R
S
L
Q
L
I
K
S
F
G
I
Q
A
G
L
A
L
N
P
A
T
G
I
D
C
L
K
Y
V
E
S
---
N
I
D
R
------
V
---
L
I
M
S
V
N
P
G
F
--
Q
K
F
I
P
A
M
L
D
K
A
K
E
I
-
S
K
W
I
S
---
S
----
T
D
R
D
I
L
L
E
I
D
G
G
V
N
P
Y
N
I
A
E
I
A
V
C
G
V
N
A
F
V
A
G
S
-
A
I
F
N
S
D
-
S
Y
K
Q
T
I
D
K
M
R
D
E
L
N
--
76
HHSearch
73.66
39%
-76
- C4 -
-
3CT7
-
ALSE_ECOLI
D:
[1-217]
----------
M
K
I
S
P
S
L
M
C
M
D
L
L
K
F
K
E
Q
I
E
F
I
-
D
S
H
A
D
Y
F
H
I
D
I
M
D
G
H
F
V
P
N
L
T
L
S
P
F
F
V
S
Q
V
K
K
-
L
-
A
--
T
K
P
L
-
D
C
H
L
M
V
T
R
P
Q
D
Y
I
A
Q
L
A
R
A
G
A
D
F
I
T
L
H
P
E
--
T
--
I
-
N
--
G
Q
A
F
R
L
I
D
E
I
R
R
H
D
M
K
V
G
L
I
L
N
P
E
T
P
V
E
A
M
K
Y
Y
I
H
---
K
A
D
K
------
I
---
T
V
M
T
V
D
P
G
F
A
G
Q
P
F
I
P
E
M
L
D
K
L
A
E
L
-
K
A
W
R
E
---
R
----
E
G
L
E
Y
E
I
E
V
D
G
S
C
N
Q
A
T
Y
E
K
L
M
A
A
G
A
D
V
F
I
V
G
T
S
G
L
F
N
H
A
E
N
I
D
E
A
W
R
I
M
T
A
Q
I
---
89
HHSearch
72.13
41%
-34
- C4 -
-
3QC3
1
RPE_HUMAN
A:
[7-218]
-----------
K
I
G
P
S
I
L
N
S
D
L
A
N
L
G
A
E
C
L
R
M
L
D
S
G
A
D
Y
L
H
L
D
V
M
D
G
H
F
V
P
N
I
T
F
G
H
P
V
V
E
S
L
R
K
-
Q
-
L
GQ
D
P
F
F
-
D
M
H
M
M
V
S
K
P
E
Q
W
V
K
P
M
A
V
A
G
A
N
Q
Y
T
F
H
L
E
--
A
--
T
-
E
--
N
-
P
G
A
L
I
K
D
I
R
E
N
G
M
K
V
G
L
A
I
K
P
G
T
S
V
E
Y
L
A
P
W
A
N
---
Q
I
D
M
------
A
---
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
E
D
M
M
P
K
V
H
W
L
-
R
T
Q
-----------
F
P
S
L
D
I
E
V
D
G
G
V
G
P
D
T
V
H
K
C
A
E
A
G
A
N
M
I
V
S
G
S
-
A
I
M
R
S
E
-
D
P
R
S
V
I
N
L
L
R
N
V
C
---
13
PsiBlast_PDB
70.39
42%
-29
- C4 -
-
3OVR
5
RPE_HUMAN
A:
[6-214]
-----------
K
I
G
P
S
I
L
N
S
D
L
A
N
L
G
A
E
C
L
R
M
L
D
S
G
A
D
Y
L
H
L
D
V
M
D
G
H
F
V
P
N
I
T
F
G
H
P
V
V
E
S
L
R
K
Q
L
-
G
--
Q
D
P
F
F
D
M
H
M
M
V
S
K
P
E
Q
W
V
K
P
M
A
V
A
G
A
N
Q
Y
T
F
H
L
E
--
A
--
T
-
E
--
N
-
P
G
A
L
I
K
D
I
R
E
N
G
M
K
V
G
L
A
I
K
P
G
T
S
V
---
E
Y
L
A
P
---
W
A
N
Q
------
I
D
M
A
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
E
D
M
M
P
K
V
H
W
L
-----
R
---
T
----
Q
F
P
S
L
D
I
E
V
D
G
G
V
G
P
D
T
V
H
K
C
A
E
A
G
A
N
M
I
V
S
G
S
-
A
I
M
R
S
E
-
D
P
R
S
V
I
N
L
L
R
------
12
PsiBlast_PDB
69.72
42%
-31
- C4 -
-
3OVQ
5
RPE_HUMAN
A:
[6-214]
-----------
K
I
G
P
S
I
L
N
S
D
L
A
N
L
G
A
E
C
L
R
M
L
D
S
G
A
D
Y
L
H
L
D
V
M
D
G
H
F
V
P
N
I
T
F
G
H
P
V
V
E
S
L
R
K
Q
L
-
G
--
Q
D
P
F
F
D
M
H
M
M
V
S
K
P
E
Q
W
V
K
P
M
A
V
A
G
A
N
Q
Y
T
F
H
L
E
--
A
--
T
-
E
--
N
-
P
G
A
L
I
K
D
I
R
E
N
G
M
K
V
G
L
A
I
K
P
G
T
S
V
---
E
Y
L
A
P
---
W
A
N
Q
------
I
D
M
A
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
E
D
M
M
P
K
V
H
W
L
-----
R
---
T
----
Q
F
P
S
L
D
I
E
V
D
G
G
V
G
P
D
T
V
H
K
C
A
E
A
G
A
N
M
I
V
S
G
S
-
A
I
M
R
S
E
-
D
P
R
S
V
I
N
L
L
R
------
14
PsiBlast_PDB
69.64
40%
-33
- C4 -
-
3QC3
1
RPE_HUMAN
A:
[6-215]
----------
C
K
I
G
P
S
I
L
N
S
D
L
A
N
L
G
A
E
C
L
R
M
L
D
S
G
A
D
Y
L
H
L
D
V
M
D
G
H
F
V
P
N
I
T
F
G
H
P
V
V
E
S
L
R
K
Q
L
-
G
--
Q
D
P
F
F
D
M
H
M
M
V
S
K
P
E
Q
W
V
K
P
M
A
V
A
G
A
N
Q
Y
T
F
H
L
E
--
A
--
T
-
E
--
N
-
P
G
A
L
I
K
D
I
R
E
N
G
M
K
V
G
L
A
I
K
P
G
T
S
V
---
E
Y
L
A
P
---
W
A
N
Q
------
I
D
M
A
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
E
D
M
M
P
K
V
H
W
L
-----
R
---
T
----
Q
F
P
S
L
D
I
E
V
D
G
G
V
G
P
D
T
V
H
K
C
A
E
A
G
A
N
M
I
V
S
G
S
-
A
I
M
R
S
E
-
D
P
R
S
V
I
N
L
L
R
------
51
PsiBlast_CBE
69.56
42%
-27
- C4 -
-
3OVR
4
RPE_HUMAN
B:
[6-214]
-----------
K
I
G
P
S
I
L
N
S
D
L
A
N
L
G
A
E
C
L
R
M
L
D
S
G
A
D
Y
L
H
L
D
V
M
D
G
H
F
V
P
N
I
T
F
G
H
P
V
V
E
S
L
R
K
Q
L
-
G
--
Q
D
P
F
F
D
M
H
M
M
V
S
K
P
E
Q
W
V
K
P
M
A
V
A
G
A
N
Q
Y
T
F
H
L
E
--
A
--
T
-
E
--
N
-
P
G
A
L
I
K
D
I
R
E
N
G
M
K
V
G
L
A
I
K
P
G
T
S
V
---
E
Y
L
A
P
---
W
A
N
Q
------
I
DMA
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
E
D
M
M
P
K
V
H
W
L
-----
R
---
T
----
Q
F
P
S
L
D
I
E
V
D
G
G
V
G
P
D
T
V
H
K
C
A
E
A
G
A
N
M
I
V
S
G
S
-
A
I
M
R
S
E
-
D
P
R
S
V
I
N
L
L
R
------
52
PsiBlast_CBE
69.03
42%
-30
- C4 -
-
3OVQ
4
RPE_HUMAN
B:
[6-214]
-----------
K
I
G
P
S
I
L
N
S
D
L
A
N
L
G
A
E
C
L
R
M
L
D
S
G
A
D
Y
L
H
L
D
V
M
D
G
H
F
V
P
N
I
T
F
G
H
P
V
V
E
S
L
R
K
Q
L
-
G
--
Q
D
P
F
F
D
M
H
M
M
V
S
K
P
E
Q
W
V
K
P
M
A
V
A
G
A
N
Q
Y
T
F
H
L
E
--
A
--
T
-
E
--
N
-
P
G
A
L
I
K
D
I
R
E
N
G
M
K
V
G
L
A
I
K
P
G
T
S
V
---
E
Y
L
A
P
---
W
A
N
Q
------
I
D
M
A
L
V
M
T
V
E
P
G
F
G
G
Q
K
F
M
E
D
M
M
P
K
V
H
W
L
-----
R
---
T
----
Q
F
P
S
L
D
I
E
V
D
G
G
V
G
P
D
T
V
H
K
C
A
E
A
G
A
N
M
I
V
S
G
S
-
A
I
M
R
S
E
-
D
P
R
S
V
I
N
L
L
R
------