@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y1G5: (2018-01-25 )
MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTLLNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYWQSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDPGSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAIYRKLYEV
Atome Classification :
(20 SA)
-....-.....10--...--.....20........30........40........50........60----.--...----.---...---.-----70........80...---------.....90.-------.....----.-----.-100.------.-----.-----.....----110-....--------.----...120.....-..130.......140.......150.......160.......170....-...180.......190.......200.......210.......220...---------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-
M
T
L
L
-
I
KNMNM
K
--
R
G
K
--
K
R
V
I
R
Q
L
N
L
LVESG
E
V
A
A
L
IAPNGFG
K
T
T
L
L
N
G
I
A
Q
L
LPTT
Y
D
QLS-----L--HNI----S---P
T
A
---
Y
-----
T
D
Y
R
R
S
F
F
F
LEST
N
Q
---------
L
S
D
Y
L
S
A
V
-------
D
Y
L
T
L
----
I
-----
K
-
Y
-
Y
W
------Q-----S-----KV
E
C
Q
----
T
V
--
F
Q
R
L--------K----MT
E
Y
L
TLP
I
G
K
-
M
SLG
M
K
Q
H
V
L
L
A
A
Y
L
ISD
S
S
V
M
L
FDEPLNGLDPG
S
I
D
I
L
N
S
L
I
R
Q
W
Q
KE-G
K
T
I
L
LS
S
H
A
I
A
N
I
Q
S
I
C
S
K
A
CFLKNG
E
I
VTESS
N
M
E
E
I
L
A
I
Y
R
K
L
YEV---------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.26
26%
-49
- C1 -
-
1VPL
-
?
A:
[15-238]
--
A
V
V
-
V
K
D
L
R
K
R
--
I
G
K
--
K
E
I
L
K
G
I
S
F
E
I
E
E
G
E
I
F
G
L
I
G
P
N
G
A
G
K
T
T
T
L
R
I
I
S
T
L
I
K
P
S
S
G
I
V
T
-----
V
FG
K
N
V
----
V
---
E
E
P
---
H
------
E
V
R
K
L
I
S
Y
L
P
E
E
A
G
---------
A
Y
R
N
M
Q
G
I
-------
E
Y
L
R
F
----
V
-----
A
G
F
-
Y
A
------
S
-----
S
-----
S
S
E
I
E
----
E
M
--
V
E
R
A
--------
T
E
I
A
G
L
G
E
K
I
K
D
R
V
S
T
-
Y
S
K
G
M
V
R
K
L
L
I
A
R
A
L
M
V
N
P
R
L
A
I
L
D
E
P
T
S
G
L
D
V
L
N
A
R
E
V
R
K
I
L
K
Q
A
S
Q
E
-
G
L
T
I
L
V
S
S
H
N
M
L
E
V
E
F
L
C
D
R
I
A
L
I
H
N
G
T
I
V
-
E
T
G
T
V
E
E
L
K
E
R
Y
K
--------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
76.02
24%
-68
- C1 -
-
4WBS
-
?
A:
[39-261]
--
S
L
V
-
V
R
N
L
K
K
R
--
Y
G
S
--
R
T
V
V
K
D
V
S
L
D
V
K
S
G
E
V
V
G
L
L
G
P
N
G
A
G
K
T
T
S
F
Y
M
I
V
G
L
V
P
L
D
A
G
E
I
D
-----
L
--
D
G
K
----
S
---
I
S
L
---
L
-----
P
I
H
K
R
A
S
L
G
L
S
Y
L
P
Q
EASVFRKLS
V
E
E
N
I
R
A
V
L
E
L
QVGD
D
G
K
R
L
----
S
-----
K
-
D
-
A
I
------
A
-----
S
-----
R
T
E
A
------
L
--
L
D
E
L
--------
Q
----
I
S
H
L
R
E
N
P
A
L
S
-
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
T
N
P
S
F
I
L
L
D
E
P
F
A
G
V
D
P
I
A
V
L
E
I
Q
K
I
V
K
F
L
K
Q
R
-
N
I
G
V
L
I
T
D
H
N
V
R
E
T
L
G
I
C
D
H
A
Y
I
I
S
D
G
S
V
L
A
A
G
A
------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
74.25
28%
-31
- C1 -
-
4YMW
-
?
J:
[12-226]
----------------
G
S
--
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
-----
I
--
D
G
V
KINN
G
---
K
V
N
---
I
-----
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
---------
L
F
P
H
L
T
A
I
-------
E
N
I
T
L
AP--
V
-----
K
-
V
-
K
K
------
M
-----
N
-----
K
K
E
A
E
----
E
L
--
A
V
D
L
LAKVGLLD
K
----
K
D
Q
Y
---
P
I
-
K
-
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
-
E
E
I
F
--
Y
R
--------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
73.76
27%
-26
- C1 -
-
4RVC
-
?
A:
[2-217]
--
T
L
L
E
V
K
D
L
S
G
G
--
Y
T
A
--
Q
N
V
L
E
D
V
T
F
V
V
D
R
G
E
M
V
A
L
I
G
L
N
G
A
G
K
S
T
T
I
K
H
I
I
G
L
M
E
P
R
R
G
A
I
S
-----
I
--
N
G
Y
----
R
L--
A
D
G
---
P
-----
E
T
Y
R
R
Q
F
A
Y
I
P
E
T
P
V
---------
L
Y
E
E
L
T
L
E
-------
E
H
L
R
L
----
A
-----
A
-
M
A
Y
G
------
L
-----
S
-----
E
A
E
Y
E
R
R
L
P
P
L
--
L
R
E
F
--------
R
----
L
E
R
R
L
S
S
F
P
A
H
-
F
S
K
G
M
K
Q
K
V
M
I
V
C
A
F
L
L
E
P
P
L
Y
I
I
D
E
P
F
L
G
L
D
P
L
A
I
H
A
L
L
E
R
M
N
E
Q
K
A
K
-
G
A
G
I
L
L
S
T
H
I
L
A
T
A
E
R
Y
C
D
S
F
V
I
L
H
N
G
R
V
K
A
K
G
T
------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
73.32
28%
-27
- C1 -
-
4YMV
1
?
J:
[12-226]
----------------
G
S
--
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
-----
I
--
D
G
V
KINN
G
---
K
V
N
---
I
-----
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
---------
L
F
P
H
L
T
A
I
-------
E
N
I
T
L
AP--
V
-----
K
-
V
-
K
K
------
M
-----
N
-----
K
K
E
A
E
----
E
L
--
A
V
D
L
LAKVGLLD
K
----
K
D
Q
Y
---
P
I
-
K
-
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
-
E
E
I
F
--
Y
R
--------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
72.54
28%
-26
- C1 -
-
4YMS
-
?
J:
[12-226]
----------------
G
S
--
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
-----
I
--
D
G
V
KINN
G
---
K
V
N
---
I
-----
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
---------
L
F
P
H
L
T
A
I
-------
E
N
I
T
L
AP--
V
-----
K
-
V
-
K
K
------
M
-----
N
-----
K
K
E
A
E
----
E
L
--
A
V
D
L
LAKVGLLD
K
----
K
D
Q
Y
---
P
I
-
K
-
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
-
E
E
I
F
--
Y
R
--------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
72.39
24%
-29
- C1 -
-
4U02
-
?
A:
[7-226]
------
I
R
N
L
H
K
W
--
F
G
P
--
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
-----
V
--
D
G
L
----
S
VKD
D
R
A
---
L
-----
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
---------
L
F
P
H
M
T
V
L
-------
E
N
V
T
L
APMR
V
-----
R
-
R
-
W
P
------
R
-----
E
-----
K
A
E
K
K
----
A
L
E
L
L
E
R
V
--------
G
----
I
L
D
Q
A
R
K
Y
P
A
Q
-
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-
E
E
G
R
P
E
E
I
F
------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
72.38
28%
-26
- C1 -
-
4YMU
1
?
J:
[12-226]
----------------
G
S
--
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
-----
I
--
D
G
V
KINN
G
---
K
V
N
---
I
-----
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
---------
L
F
P
H
L
T
A
I
-------
E
N
I
T
L
AP--
V
-----
K
-
V
-
K
K
------
M
-----
N
-----
K
K
E
A
E
----
E
L
--
A
V
D
L
LAKVGLLD
K
----
K
D
Q
Y
---
P
I
-
K
-
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
-
E
E
I
F
--
Y
R
--------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
71.56
28%
-27
- C1 -
-
4YMT
-
?
J:
[12-226]
----------------
G
S
--
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
-----
I
--
D
G
V
KINN
G
---
K
V
N
---
I
-----
N
K
V
R
Q
K
V
G
M
V
F
Q
H
F
N
---------
L
F
P
H
L
T
A
I
-------
E
N
I
T
L
AP--
V
-----
K
-
V
-
K
K
------
M
-----
N
-----
K
K
E
A
E
----
E
L
--
A
V
D
L
LAKVGLLD
K
----
K
D
Q
Y
---
P
I
-
K
-
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
-
E
E
I
F
--
Y
R
--------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
71.49
23%
-45
- C1 -
-
4P32
1
LPTB_ECOLI
A:
[2-222]
--
T
L
T
-
A
K
N
L
A
K
A
--
Y
K
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
-----
I
--
D
D
D
----
D
---
I
S
L
LP
L
H
-----
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
---------
I
F
R
R
L
S
V
Y
-------
D
N
L
M
A
----
V
-----
L
-
Q
-
I
R
DDLS
A
E
Q
-----
R
-----
E
D
R
A
N
----
E
L
--
M
E
E
F
--------
H
----
I
-
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
---------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
70.94
23%
-42
- C1 -
-
4QC2
1
?
A:
[3-223]
--
T
L
T
-
A
K
N
L
A
K
A
--
Y
K
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
-----
I
--
D
D
D
----
D
---
I
S
L
LP
L
H
-----
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
---------
I
F
R
R
L
S
V
Y
-------
D
N
L
M
A
----
V
-----
L
-
Q
-
I
R
DDLS
A
E
Q
-----
R
-----
E
D
R
A
N
----
E
L
--
M
E
E
F
--------
H
----
I
-
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
E
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
---------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
70.67
24%
-29
- C1 -
-
4U00
1
?
A:
[7-226]
------
I
R
N
L
H
K
W
--
F
G
P
--
L
H
V
L
K
G
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
-----
V
--
D
G
L
----
S
VKD
D
R
A
---
L
-----
R
E
I
R
R
E
V
G
M
V
F
Q
Q
F
N
---------
L
F
P
H
M
T
V
L
-------
E
N
V
T
L
A
P
M
R
V
-----
R
-
R
-
W
P
------
R
-----
E
-----
K
A
E
K
K
----
A
L
E
L
L
E
R
V
--------
G
----
I
L
D
Q
A
R
K
Y
P
A
Q
-
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
D
V
M
R
D
L
A
Q
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
A
D
R
V
V
F
M
D
G
G
Q
I
V
-
E
E
G
R
P
E
E
I
F
------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
70.37
23%
-29
- C1 -
-
4YER
2
?
A:
[5-251]
--
I
I
V
-
V
E
N
L
V
K
K
--
F
G
D
--
F
E
A
V
K
G
V
S
F
S
V
K
K
G
E
I
F
A
F
L
G
P
N
G
A
G
K
T
T
T
I
H
M
L
T
T
L
L
K
P
T
S
G
K
A
W
-----
V
--
A
G
H
----
D
---
V
L
K
---
E
P
----
R
E
V
R
R
K
I
G
I
V
F
Q
D
Q
S
---------
L
D
R
E
L
T
A
Y
-------
E
N
M
Y
I
----
H
-----
G
-
K
-
I
Y
------
G
-----
Y
G
G
E
K
L
K
K
R
I
L
----
E
L
--
L
E
F
V
--------
E
----
L
L
E
F
K
D
K
P
V
K
T
-
F
S
G
G
M
A
R
R
L
E
I
A
R
S
L
I
H
E
P
E
V
L
F
L
D
E
P
T
I
G
L
D
P
H
T
R
A
H
M
W
E
Y
I
S
K
M
K
K
E
H
N
M
T
I
F
L
T
T
H
Y
M
D
E
A
E
Q
L
A
D
R
V
A
I
I
D
H
G
K
I
I
A
L
G
T
P
T
E
---------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
69.07
23%
-50
- C1 -
-
3RLF
2
MALK_ECOLI
A:
[2-220]
-
A
S
V
Q
-
L
Q
N
V
T
K
A
--
W
G
E
--
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
-----
I
--
G
E
K
----
R
---
M
N
D
---
T
-----
P
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
---------
L
Y
P
H
L
S
V
A
-------
E
N
M
S
F
----
G
-----
L
-
K
-
L
A
------
G
-----
A
K
K
E
V
I
N
Q
R
V
N
----
Q
V
--
A
E
V
L
--------
Q
----
L
A
H
L
L
D
R
K
P
K
A
-
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
---------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
67.95
23%
-48
- C1 -
-
2AWN
1
MALK_ECOLI
B:
[2-220]
-
A
S
V
Q
-
L
Q
N
V
T
K
A
--
W
G
E
--
V
V
V
S
K
D
I
N
L
D
I
H
E
G
E
F
V
V
F
V
G
P
S
G
C
G
K
S
T
L
L
R
M
I
A
G
L
E
T
I
T
S
G
D
L
F
-----
I
--
G
E
K
----
R
---
M
N
D
---
T
-----
P
P
A
E
R
G
V
G
M
V
F
Q
S
Y
A
---------
L
Y
P
H
L
S
V
A
-------
E
N
M
S
F
----
G
-----
L
-
K
-
L
A
------
G
-----
A
K
K
E
V
I
N
Q
R
V
N
----
Q
V
--
A
E
V
L
--------
Q
----
L
A
H
L
L
D
R
K
P
K
A
-
L
S
G
G
Q
R
Q
R
V
A
I
G
R
T
L
V
A
E
P
S
V
F
L
L
D
E
P
L
S
N
L
D
A
A
L
R
V
Q
M
R
I
E
I
S
R
L
H
K
R
L
G
R
T
M
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
K
I
V
V
L
D
A
G
R
V
A
Q
V
G
K
P
L
E
---------------------------------------------------------------------------------------------------------------------------------
36
HHSearch
66.83
25%
-7
- C1 -
-
1OXX
-
?
K:
[2-227]
-
V
R
I
I
-
V
K
N
V
S
K
V
--
F
K
K
GK
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
-----
F
--
D
D
R
----
L
---
V
A
S
---
N
GKLIV
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
---------
L
Y
P
N
L
T
A
F
-------
E
N
I
A
F
----
P
-----
L
-
T
-
N
M
------
K
MSKEE
I
-----
R
K
R
V
E
----
E
V
--
A
K
I
L
--------
D
----
I
H
H
V
L
N
H
F
P
R
E
-
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
---------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
66.71
23%
-46
- C1 -
-
2YYZ
1
?
A:
[3-220]
--
S
I
R
-
V
V
N
L
K
K
Y
--
F
G
K
--
V
K
A
V
D
G
V
S
F
E
V
K
D
G
E
F
V
A
L
L
G
P
S
G
C
G
K
T
T
T
L
L
M
L
A
G
I
Y
K
P
T
S
G
E
I
Y
-----
F
--
D
D
V
----
L
---
V
N
D
---
I
-----
P
P
K
Y
R
E
V
G
M
V
F
Q
N
Y
A
---------
L
Y
P
H
M
T
V
F
-------
E
N
I
A
F
----
P
-----
L
-
R
-
A
R
------
R
ISKD
E
V
-----
E
K
R
V
V
----
E
I
--
A
R
K
L
--------
L
----
I
D
N
L
L
D
R
K
P
T
Q
-
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
Q
P
K
V
L
L
F
D
E
P
L
S
N
L
D
A
N
L
R
M
I
M
R
A
E
I
K
H
L
Q
Q
E
L
G
I
T
S
V
Y
V
T
H
D
Q
A
E
A
M
T
M
A
S
R
I
A
V
F
N
Q
G
K
L
V
Q
Y
G
T
P
D
E
---------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
65.39
21%
-49
* C1 *
-
4TQU
-
?
T:
[4-221]
--
S
V
S
-
I
Q
N
V
V
K
R
--
Y
D
K
--
T
T
V
V
H
G
V
S
L
D
I
E
P
G
E
F
V
V
L
V
G
P
S
G
C
G
K
S
T
T
L
R
M
V
A
G
L
E
E
I
S
G
G
T
I
R
-----
I
--
D
G
R
----
V
---
I
N
D
---
L
-----
A
P
K
D
R
D
V
A
M
V
F
Q
N
Y
A
---------
L
Y
P
H
L
N
V
R
-------
D
N
I
S
F
----
G
-----
L
-
R
-
L
K
------
R
TKKSV
I
-----
D
A
A
V
K
----
T
A
--
A
D
I
L
--------
G
----
L
Q
P
L
L
E
R
K
P
S
D
-
L
S
G
G
Q
R
Q
R
V
A
M
G
R
A
I
V
R
D
P
K
V
F
L
F
D
Q
P
L
S
N
L
D
A
K
L
R
T
Q
M
R
A
E
I
K
R
L
H
Q
R
L
G
T
T
V
I
Y
V
T
H
D
Q
V
E
A
M
T
L
A
D
R
I
V
V
M
R
D
G
L
I
E
Q
I
G
K
P
M
D
---------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
63.88
22%
-43
- C1 -
-
4P33
6
LPTB_ECOLI
A:
[2-222]
--
T
L
T
-
A
K
N
L
A
K
A
--
Y
K
G
--
R
R
V
V
E
D
V
S
L
T
V
N
S
G
E
I
V
G
L
L
G
P
N
G
A
G
K
T
T
T
F
Y
M
V
V
G
I
V
P
R
D
A
G
N
I
I
-----
I
--
D
D
D
----
D
---
I
S
L
LP
L
H
-----
A
R
A
R
R
G
I
G
Y
L
P
Q
E
A
S
---------
I
F
R
R
L
S
V
Y
-------
D
N
L
M
A
----
V
-----
L
-
Q
-
I
R
DDLS
A
E
Q
-----
R
-----
E
D
R
A
N
----
E
L
--
M
E
E
F
--------
H
----
I
-
E
H
L
R
D
S
M
G
Q
S
L
S
G
G
E
R
R
R
V
E
I
A
R
A
L
A
A
N
P
K
F
I
L
L
D
Q
P
F
A
G
V
D
P
I
S
V
I
D
I
K
R
I
I
E
H
L
R
D
S
-
G
L
G
V
L
I
T
D
H
N
V
R
E
T
L
A
V
C
E
R
A
Y
I
V
S
Q
G
H
L
I
A
H
G
T
P
T
E
---------------------------------------------------------------------------------------------------------------------------------
48
Fugue
63.47
25%
-5
- C1 -
-
1OXS
-
?
C:
[1-352]
M
V
R
I
I
-
V
K
N
V
S
K
V
FK
K
G
K
--
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
FDDRL
V
--
A
S
N
----
G
---
K
L
I
---
V
-----
P
P
E
D
R
K
I
G
M
V
F
Q
T
W
A
---------
L
Y
P
N
L
T
A
F
-------
E
N
I
A
F
----
P
LTNMK
M
-
S
-
K
E
------
E
-----
I
-----
R
K
R
V
E
----
E
V
--
A
K
I
L
--------
D
----
I
H
H
V
L
N
H
F
P
R
E
-
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
D
P
A
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
----
P
E
D
L
Y
D
N
P
V
S
I
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