@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y1J0: (2018-01-26 )
MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLADCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALSIVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKEPEKRSRLTQ
Atome Classification :
(20 SA)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.-....-....10........20-........-30.....-...40.......--.50........60........70....-....80........90........100.......110.......120.......130........140.......150.......160.......-------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-VVK
T
-
E
T
L
E
E
K
A
R
E
L
L
K
ERGV-
T
V
E
D
I
A
Q
L
-
V
M
F
L
Q
K
D
-YISDL
T
L
A
D
C
T
E
--
S
V
N
S
V
L
T
K
R
E
V
H
N
A
I
I
TG
I
Q
L
D
I
L
A
E
K
-
K
K
L
M
S
P
L
Q
H
I
IEDDEG
L
Y
G
I
D
E
I
L
A
L
S
I
V
N
V
Y
GTIGFTNYGYIDKV
K
P
G
I
L
K
E
LN-SHD
G
V
H
V
H
T
F
L
D
D
I
V
G
A
I
A
A
A
A
A
S
R
L
AHKE
P
E
K
R
SRLTQ-------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
85.07
67%
-143
- C2 -
-
1Y9I
1
?
D:
[6-164]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
-
S
A
L
E
S
K
A
R
S
W
L
I
E
R
G
V
-
E
I
D
D
I
A
E
L
-
V
L
F
L
Q
Q
K
-
Y
H
P
G
L
E
L
D
I
C
R
Q
--
N
V
E
H
V
L
R
K
R
E
V
Q
N
A
V
L
T
G
I
Q
L
D
V
M
A
E
K
-
G
E
L
V
Q
P
L
Q
N
I
I
S
A
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
V
K
P
G
I
L
A
K
L
N
-
E
H
D
G
I
A
V
H
T
F
L
D
D
I
V
G
A
I
A
A
A
A
A
S
R
L
A
H
S
Y
H
D
--------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
84.13
70%
-146
- C2 -
-
1Y9I
1
?
D:
[6-160]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
-
S
A
L
E
S
K
A
R
S
W
L
I
E
R
G
V
-
E
I
D
D
I
A
E
L
-
V
L
F
L
Q
Q
K
-
Y
H
P
G
L
E
L
D
I
C
R
Q
--
N
V
E
H
V
L
R
K
R
E
V
Q
N
A
V
L
T
G
I
Q
L
D
V
M
A
E
K
-
G
E
L
V
Q
P
L
Q
N
I
I
S
A
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
V
K
P
G
I
L
A
K
L
N
-
E
H
D
G
I
A
V
H
T
F
L
D
D
I
V
G
A
I
A
A
A
A
A
S
R
L
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
83.44
70%
-142
- C2 -
-
1Y9I
1
?
C:
[6-160]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
-
S
A
L
E
S
K
A
R
S
W
L
I
E
R
G
V
-
E
I
D
D
I
A
E
L
-
V
L
F
L
Q
Q
K
-
Y
H
P
G
L
E
L
D
I
C
R
Q
--
N
V
E
H
V
L
R
K
R
E
V
Q
N
A
V
L
T
G
I
Q
L
D
V
M
A
E
K
-
G
E
L
V
Q
P
L
Q
N
I
I
S
A
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
V
K
P
G
I
L
A
K
L
N
-
E
H
D
G
I
A
V
H
T
F
L
D
D
I
V
G
A
I
A
A
A
A
A
S
R
L
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
82.99
70%
-141
- C2 -
-
1Y9I
-
?
A:
[6-160]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
-
S
A
L
E
S
K
A
R
S
W
L
I
E
R
G
V
-
E
I
D
D
I
A
E
L
-
V
L
F
L
Q
Q
K
-
Y
H
P
G
L
E
L
D
I
C
R
Q
--
N
V
E
H
V
L
R
K
R
E
V
Q
N
A
V
L
T
G
I
Q
L
D
V
M
A
E
K
-
G
E
L
V
Q
P
L
Q
N
I
I
S
A
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
V
K
P
G
I
L
A
K
L
N
-
E
H
D
G
I
A
V
H
T
F
L
D
D
I
V
G
A
I
A
A
A
A
A
S
R
L
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
82.23
70%
-148
* C2 *
-
1Y9I
1
?
B:
[6-160]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
Q
-
S
A
L
E
S
K
A
R
S
W
L
I
E
R
G
V
-
E
I
D
D
I
A
E
L
-
V
L
F
L
Q
Q
K
-
Y
H
P
G
L
E
L
D
I
C
R
Q
--
N
V
E
H
V
L
R
K
R
E
V
Q
N
A
V
L
T
G
I
Q
L
D
V
M
A
E
K
-
G
E
L
V
Q
P
L
Q
N
I
I
S
A
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
V
K
P
G
I
L
A
K
L
N
-
E
H
D
G
I
A
V
H
T
F
L
D
D
I
V
G
A
I
A
A
A
A
A
S
R
L
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------
40
HHSearch
82.16
65%
-136
- C2 -
-
1RFZ
-
?
A:
[7-164]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
M
-
N
N
L
E
Q
T
A
R
R
W
L
E
E
R
G
V
-
T
V
E
K
I
A
E
L
-
V
Y
Y
L
Q
S
K
-
Y
H
P
D
L
T
M
E
E
C
I
E
--
N
V
N
R
V
I
S
K
R
E
V
Q
N
A
I
L
T
G
I
Q
L
D
K
L
A
E
D
-
G
R
L
D
E
P
L
Q
S
I
I
R
R
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
Q
K
P
G
I
L
Q
Y
L
N
-
D
K
S
T
G
K
C
N
T
F
L
D
D
I
V
G
A
I
A
A
A
A
S
S
R
L
A
H
R
A
----------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.19
68%
-140
- C2 -
-
1RFZ
-
?
A:
[11-163]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
E
Q
T
A
R
R
W
L
E
E
R
G
V
-
T
V
E
K
I
A
E
L
-
V
Y
Y
L
Q
S
K
-
Y
H
P
D
L
T
M
E
E
C
I
E
--
N
V
N
R
V
I
S
K
R
E
V
Q
N
A
I
L
T
G
I
Q
L
D
K
L
A
E
D
-
G
R
L
D
E
P
L
Q
S
I
I
R
R
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
Q
K
P
G
I
L
Q
Y
L
N
-
D
K
S
T
G
K
C
N
T
F
L
D
D
I
V
G
A
I
A
A
A
A
S
S
R
L
A
H
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
75.25
66%
-9
- C2 -
-
1RFZ
-
?
A:
[1-164]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S
N
A
M
S
E
F
I
M
N
N
L
E
Q
T
A
R
R
W
L
E
E
R
G
V
-
T
V
E
K
I
A
E
L
-
V
Y
Y
L
Q
S
K
-
Y
H
P
D
L
T
M
E
E
C
I
E
--
N
V
N
R
V
I
S
K
R
E
V
Q
N
A
I
L
T
G
I
Q
L
D
K
L
A
E
D
-
G
R
L
D
E
P
L
Q
S
I
I
R
R
D
E
G
L
Y
G
V
D
E
I
L
A
L
S
I
V
N
V
Y
G
S
I
G
F
T
N
Y
G
Y
I
D
K
Q
K
P
G
I
L
Q
Y
L
N
-
D
K
S
T
G
K
C
N
T
F
L
D
D
I
V
G
A
I
A
A
A
A
S
S
R
L
A
H
R
A
----------------------------------------------------------------------------------------------------------------------------------------------------------
38
HHSearch
75.13
52%
-149
- C2 -
-
1TLQ
-
YPJQ_BACSU
A:
[6-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
T
M
-
N
E
M
V
D
I
T
K
D
M
L
N
K
R
G
V
-
M
I
E
D
I
A
R
I
-
V
Q
K
L
Q
E
K
-
Y
N
P
N
L
P
L
S
V
C
M
E
--
N
V
E
K
V
L
N
K
R
E
I
I
H
A
V
L
T
G
L
A
L
D
Q
L
A
E
Q
-
K
L
L
P
E
P
L
Q
H
L
V
E
T
D
E
P
L
Y
G
I
D
E
I
I
P
L
S
I
V
N
V
Y
G
S
I
G
L
T
N
F
G
Y
L
D
K
E
K
I
G
I
I
K
E
L
D
-
E
S
-
P
D
G
I
H
T
F
L
D
D
I
V
A
A
L
A
A
A
A
A
S
R
I
A
H
T
H
Q
D
L
Q
------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
72.75
60%
-135
- C2 -
-
1TLQ
-
YPJQ_BACSU
A:
[15-160]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
K
D
M
L
N
K
R
G
V
-
M
I
E
D
I
A
R
I
-
V
Q
K
L
Q
E
K
-
Y
N
P
N
L
P
L
S
V
C
M
E
--
N
V
E
K
V
L
N
K
R
E
I
I
H
A
V
L
T
G
L
A
L
D
Q
L
A
E
Q
-
K
L
L
P
E
P
L
Q
H
L
V
E
T
D
E
P
L
Y
G
I
D
E
I
I
P
L
S
I
V
N
V
Y
G
S
I
G
L
T
N
F
G
Y
L
D
K
E
K
I
G
I
I
K
E
L
D
E
S
P
D
G
--
I
H
T
F
L
D
D
I
V
A
A
L
A
A
A
A
A
S
R
I
A
H
------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
40.03
32%
-183
- C- -
-
1G39
-
HNF1A_MOUSE
A:
[1-28]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-
V
S
K
L
-
S
Q
L
Q
T
E
L
L
A
A
L
L
E
S
G
L
-
S
K
E
A
L
I
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
HHSearch
39.01
24%
-197
- C2 -
-
4Q2U
-
DINJ_ECOLI
I:
[12-40]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
E
D
L
K
N
Q
A
A
D
V
L
A
G
M
G
L
-
T
I
S
D
L
V
R
I
-
T
L
T
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
HHSearch
34.57
50%
-257
- C2 -
-
5J10
-
?
B:
[20-47]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
L
L
K
E
I
K
K
-
L
V
E
E
I
A
R
L
-
V
K
E
I
Q
E
D
-
P
S
D
E
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
32.71
21%
-89
- C2 -
-
2K29
-
RELB_ECOLI
A:
[9-37]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
D
E
L
K
A
R
S
Y
A
A
L
E
K
M
G
V
-
T
P
S
E
A
L
R
L
-
M
L
E
Y
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
31.04
33%
-144
- C1 -
-
4Y2W
-
ALR1_CALS4
A:
[195-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
K
-
K
R
L
K
I
P
L
K
H
I
A
N
------------
A
A
A
I
L
N
L
-------
N
Y
S
H
L
D
M
V
R
P
G
I
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
29.89
13%
42
- C2 -
-
4UM2
1
EST1A_HUMAN
A:
[1-582]
S
M
E
L
H
R
L
L
R
V
A
D
N
Q
E
L
Q
L
S
N
L
L
S
RDRIS
P
E
G
L
E
K
M
A
Q
L
R
A
E
L
L
Q
L
Y
E
R
C
I
L
L
D
I
E
F
S
D
N
Q
N
V
D
Q
I
L
W
K
N
AF
Y
Q
V
I
E
K
F
R
Q
L
V
K
DPNVEN
P
E
Q
I
R
N
R
L
L
E
L
L
D
E
G
S
D
F
F
D
S
L
L
Q
K
L
Q
V
T
Y
KFKLEDYMDGLAIRLR
K
T
V
K
Y
A
L
I
S
A
Q
R
C
M
I
C
Q
G
D
I
A
R
Y
R
E
Q
A
S
DTANY
G
K
A
R
S
W
Y
L
K
A
Q
H
I
APKNG
R
P
Y
N
Q
L
A
L
L
A
V
Y
T
RR
K
L
D
A
V
Y
Y
Y
M
R
S
L
A
A
-
S
N
P
I
-
L
T
A
K
E
S
L
M
S
L
F
E
E
T
K
R
-
K
A
E
Q
M
---------
E
K
-
G
L
G
S
L
S
P
S
D
L
N
K
--
R
F
I
L
S
F
L
--
H
A
H
G
K
L
F
T
R
I
G
M
E
T
F
P
A
V
A
E
K
V
L
K
E
F
Q
V
L
L
Q
H
S
P
S
P
I
G
S
T
R
M
L
Q
L
M
T
I
N
M
F
A
V
H
N
S
---------
Q
R
S
V
I
Q
E
Q
A
-
A
A
L
G
L
A
M
F
S
L
L
V
R
R
C
T
C
L
L
K
E
S
L
S
S
P
E
D
Q
D
D
Q
D
D
I
K
V
S
S
FV
P
D
L
K
E
L
L
P
S
V
K
V
W
S
D
W
M
L
G
Y
PDTWNPPPTSLDLPSHVAVD
V
W
S
T
L
A
D
F
C
N
I
L
T
A
VNQSE
V
P
L
Y
KDPDDD
L
T
L
L
I
L
E
E
D
R
L
L
SGFVPLLAAPQ
D
P
C
Y
V
E
KTSD
K
V
I
A
A
D
C
K
R
V
T
V
L
K
Y
F
L
E
A
L
C
G
QEEPLLAFKGG
K
Y
V
S
VAPV
44
HHSearch
29.56
23%
-147
- C2 -
-
2KZ3
-
RA51D_HUMAN
A:
[10-47]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
G
L
T
E
E
M
I
Q
L
L
R
S
H
R
I
K
T
V
V
D
L
V
S
A
D
L
E
E
V
A
Q
K
C
G
L
S
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
28.80
32%
-110
- C2 -
-
3OQJ
1
CDLS_BACLD
A:
[13-82]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
T
-
E
T
L
T
Q
N
C
N
E
I
L
K
R
R
R
H
-
V
L
V
G
I
S
P
F
-
N
S
R
F
S
E
D
-
Y
I
H
R
L
I
A
W
A
V
R
E
F
Q
S
V
S
V
L
L
A
G
K
E
A
A
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
28.36
32%
-110
- C2 -
-
3OQI
2
CDLS_BACLD
A:
[13-73]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
K
T
-
E
T
L
T
Q
N
C
N
E
I
L
K
R
R
R
H
-
V
L
V
G
I
S
P
F
-
N
S
R
F
S
E
D
-
Y
I
H
R
L
I
A
W
A
V
R
E
FQ
S
V
S
V
L
L
A
G
K
E
A
A
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
28.12
32%
-120
- C2 -
-
3OQH
-
CDLS_BACLD
A:
[12-82]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
K
T
-
E
T
L
T
Q
N
C
N
E
I
L
K
R
R
R
H
-
V
L
V
G
I
S
P
F
-
N
S
R
F
S
E
D
-
Y
I
H
R
L
I
A
W
A
V
R
E
F
Q
S
V
S
V
L
L
A
G
K
E
A
A
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------