@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y1V5: (2018-01-27 )
MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQRELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQYIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFPEGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISEHINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYFETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIPRIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYRFTEAQKQALEYYQKLEESLRFNDEARKYLKELL
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-...----.10-........20..----...--..-.30..---..--....40..--......50...-----.....60.....---...70...--.....80--------------....--.....90........100...--------....110...-.-.....120....--------------...130...-----------..-------------..140...-----------....150.-----....--..160---....-------------------------.....170..----------.....180.--..-----..-----..190.......200....---...210........--------220--.-------------...--------...230-------------...--------..-..---------------------..240----------..----......250.....-.---------.260-----...----.....270.......280..----------------------....----------.290.......300...-----------....310.......320-.....----------------..---.330.......340-------.......350.----......360.......370------...------------------.....380.......390----........400..--.....410.--......420...--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
E
W
Q
-
S
V
F
----
E
E
W
-
F
P
K
E
ISKSY
P
I
K
----
I
S
K
--QY-TSS
Q
R
---
W
E
--
I
Y
A
K
L
T
K
K
--
Q
R
E
L
V
D
K
H
R
R
Y
-----
L
I
S
S
R
F
M
E
E
H
YL---A
A
T
D
W
V
FS--DFKIN
P
---------------
F
F
RT--KRS
Q
Q
K
L
Y
C
ECGR
E
L
K
V
Q
Y
I
V
--------KSPKT--
G
K
I
-
L
-
K
L
G
I
N
H
F
A
D
HLH--------------VS
P
T
V
A
A
S
I
-----------
H
Q-------------G
M
T
K
V
D
L
A
-----------
L
D
E
L
L
W
L
K
-----QKNI--DF
P
-----
E
G
L
W
-------------------------
Q
K
Y
C
F
V
L
YQN----------RRMKQPYLP--
D
I
-----
K
L
-----
A
Q
R
L
A
E
F
R
QVEM
P
I
Y
IA
D
Y
---
Q
A
L
E
N
-
E
I
K
K
I
S
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H--------IN
G
--
Q
-------------
S
K
K
--------
R
Q
I
K
---------------
K
E
L
--------
F
D
-
D
F
---------------------
A
E
E
L
-----------
V
K
----
D
V
E
E
F
L
I
N
Y
R
A
F
L
R
-
K
---------
D
W
Q
------
S
I
V
----
Y
EEVPVH
P
N
A
Y
F
E
T
F
I
S
V
L
R
----------------------
K
T
KR----------QRTP
E
V
T
A
Q
M
E
Y
F
AKNQ-----------RFIQP
K
I
Y
L
F
I
W
K
Q
Y
C
--RYGFT----------------
E
G
---
F
F
D
S
I
P
R
I
V
R
N
G
F
L
-------
K
V
L
R
K
E
R
E
A
I
Q
----SADKKDRTV
S
K
E
K
W
Q
L
V
V
-------
K
D
I------------------QSG
N
V
Q
E
T
I
D
K
WKGKHY-----R
F
T
E
A
Q
K
Q
A
L
E
Y
Y
--
Q
K
L
E
E
SLRF--
N
D
E
A
R
K
Y
L
K
E
LL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
64.21
13%
20
- C6 -
-
4BB9
1
GCKR_HUMAN
A:
[6-606]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFQHVIET
P
E
P
G
K
-
W
E
L
----
S
G
Y
-
E
A
A
V
P
I
T
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K
S
N
P
----
L
T
Q
--
D
L
-
D
K
A
D
A
---
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N
--
I
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L
G
Q
C
--
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A
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F
Q
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-----
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L
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M
V
---
Q
V
A
G
K
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A
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--
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Y
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D
R
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R
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S
A
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A
G
Q
M
-----------
D
C
C
M
N
N
TAV
F
L
P
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L
V
G
F
N
P
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M
A
RNDPIEDWSST
F
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V
A
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-----
Q
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M
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--
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-----
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LNPAIGPEGLSGSSRM
K
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A
A
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L
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--------
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P
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DHSDMFNQ
K
A
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-----------
T
N
----
Q
G
P
Q
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S
Q
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D
F
L
T
-
S
---------
I
L
P
SLTEI
D
T
V
V
----
F
I
F
T
L
D
D
N
L
T
E
V
Q
T
I
V
E
Q
V
K
E
K
TNH
I
Q
A
L
A
H
S
T
VGQTLP
I
P
L
K
K
L
F
----------
P
S
I
I
S
I
T
W
P
L
L
F
F
E
Y
E
G
-----------
N
F
I
Q
K
F
Q
R
E
L
S
T
K
W
V
L
--
N
T
V
S
T
----------------
G
A
---
H
V
L
L
-
G
K
I
L
Q
N
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M
L
DLRISN
S
K
L
F
W
R
A
L
A
M
L
Q
----
R
F
S
G
Q
S
K
A
R
C
I
E
S
L
L
R
A
I
H
FPQPLS
D
D
I
------------------
R
A
A
P
I
S
C
H
V
Q
V
A
H
E
K
E
Q
-----
V
I
P
I
A
L
L
S
L
L
F
R
C
S
I
T
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A
Q
A
H
L
A
A
--
A
P
S
V
C
E
A
V
R
S
A
L
A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
60.02
14%
4
- C6 -
-
4XGC
-
ORC5_DROME
E:
[1-458]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
A
I
C
-
S
S
L
----
E
P
L
-
F
P
--
C
R
E
A
A
I
E
T
----
L
G
E
--
L
I
G
D
S
S
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T
---
Y
P
S
A
I
Y
L
F
G
H
S
G
TG
K
T
A
L
T
R
A
F
L
K
E
-----
C
G
K
R
Q
N
V
R
T
A
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L
---
N
A
I
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C
Y
T
T
--
K
I
M
L
E
I
---------------
L
L
D
S
L
A
P
D
Q
G
D
A
L
K
V
D
N
M
L
D
F
V
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Q
L
R
R
--------
Q
A
A
T
R
VE
D
Q
G
-
F
-
L
I
A
V
D
N
A
E
R
L
R
D
--------------
M
D
A
N
V
L
P
V
L
L
R
---------
L
Q
-------------
E
L
T
N
L
N
L
C
-----------
V
I
L
L
S
Q
L
P
-----
F
E
K
F
--
Y
N
K
-----
T
G
L
S
-------------------------
E
I
V
C
L
H
L
A
Q
Y
----------
N
K
A
E
T
Q
R
I
L
--
G
S
-----
D
F
-----
Q
Q
V
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N
Q
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L
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K
K
R
L
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C
Q
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---
A
V
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D
-
F
Y
N
N
Y
L
N
L
--------
F
L
S
--
V
-------------
F
Y
K
ACRD
V
P
E
L
Q
L
T
A
---------------
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K
C
--------
L
S
-
T
Y
---------------------
L
E
P
V
-----------
L
D
----
G
T
S
R
L
W
R
H
I
A
G
P
L
R
-
S
---------
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L
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------
Q
I
-----
Y
M
R
I
E
S
L
E
L
P
Y
Y
A
K
F
L
L
I
A
A
----------------------
F
L
A
S
----------
H
N
A
A
K
Q
D
K
R
L
F
S
T
T
L
G
P
-----------
K
S
F
S
I
D
R
L
L
A
I
F
Y
A
I
L
EE
K
V
G
L
T
----------------
C
N
---
L
L
S
Q
I
S
T
L
V
H
L
N
L
L
-------
S
F
V
S
G
E
Q
N
I
M
E
----
G
----------------------------------------------
S
A
R
L
Q
C
T
I
G
---------------------
L
E
F
V
--
L
Q
I
G
K
V
V
G
F
--
N
--
V
R
Q
Y
L
C
D
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
59.87
9%
18
- C1 -
-
1EZ0
1
ALDH_VIBHA
A:
[5-508]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
N
V
F
-
Y
A
T
NAFT
G
E
A
-
L
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L
A
F
P
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----
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--
A
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A
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D
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---
A
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A
L
P
--
E
V
R
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---------------
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A
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R
L
F
A
D
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V
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S
Y
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--
P
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D
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R
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--------------
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SNFPLAFSA
A
G
-------------
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A
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P
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P
--------
I
P
F
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---------------
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GAIN
P
T
F
I
F
P
-
S
A
---------------------
M
R
A
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-----------
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----
L
A
D
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--
T
M
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V
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V
A
---
D
M
L
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S
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L
A
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-------
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T
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D
Y
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----
Q
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A
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L
V
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-------
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G
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------------------
P
T
G
V
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Y
A
M
V
H
G
G
P
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A
S
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L
--
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E
S
L
---
L
P
D
S
L
KAENPLE
I
A
R
A
V
DGKAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
58.76
13%
-28
* C5 *
-
1UJN
-
?
A:
[1-347]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
Q
R
L
E
-
V
-------------
R
E
P
V
P
Y
P
I
L
----
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G
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--------------
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--
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--
A
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L
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---
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G
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--
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W
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A
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R
N
--
A
T
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G
G
T
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-----------------
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G
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F
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-------------
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V
A
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-----------
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--
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EGKNL
V
G
A
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-------------------------
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----------
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A
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K
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---------------------
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----
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A
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-
A
---------
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---------------
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A
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M
A
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L
L
Y
A
A
L
----------------------
L
G
R
A
----------
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G
G
E
D
L
L
P
P
V
R
R
L
L
L
W
L
------------------------------------------------------------------
S
P
P
-------
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L
P
P
L
A
F
E
D
L
L
----
P
Y
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L
V
V
-------
R
P
L
------------------
P
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L
L
R
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A
F
A
A
W
R
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K
-----
G
L
---------------------------------
G
L
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
57.27
14%
45
- C2 -
-
2HCN
-
A:
[12-582]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LV
N
G
V
V
R
-
L
L
S
----
K
P
W
-
D
T
I
T
T
K
A
P
E
P
P
E
----
G
V
K
--
Y
V
-
L
N
E
T
T
---
N
W
--
L
W
A
F
L
A
R
E
--
K
R
P
R
M
C
S
R
E
E
F
-----
I
R
K
V
N
S
N
A
A
Q
W
R
---
S
A
R
E
A
V
E
D
--
P
K
F
W
E
M
---------------
V
D
E
E
--
R
E
A
H
L
R
G
E
C
H
T
C
R
A
I
W
F
M
W
L
G
--------
A
R
F
L
E
--
F
E
A
-
L
G
F
L
N
E
D
H
W
L
G
R
K
N
--------------
S
G
G
G
V
E
--------------
G
L
-------------
G
L
Q
K
L
G
Y
I
-----------
L
R
E
V
G
T
R
P
-----
G
G
R
I
Y
A
D
D
T
-----
A
G
W
D
-------------------------
T
R
I
T
R
A
D
L
E
N
----------
E
A
K
V
L
E
L
L
D
G
E
H
R
-----
R
L
-----
A
R
A
I
I
E
L
T
Y
R
S
G
Q
V
V
T
Y
A
L
---
N
T
F
T
N
-
L
A
V
Q
L
V
R
M
--------
M
E
G
--
E
GVIGPDDVEKLTK
G
K
G
--------
P
K
V
R
---------------
T
W
L
--------
S
E
-
N
G
---------------------
E
E
R
L
S
R
M
AVSGD
D
C
V
V
K
----
P
L
D
D
R
F
A
T
S
L
H
F
L
N
-
A
M
SKVRKDIQ
E
W
K
------
P
S
T
G
W
YD
W
Q
Q
V
P
F
C
S
N
----
H
F
T
E
L
I
M
----------------------
K
D
G
R
----------
T
L
V
T
P
C
R
G
Q
D
E
L
V
G
R
A
R
-----------
I
S
P
N
V
R
D
T
A
C
L
A
K
S
Y
A
--
Q
M
W
L
L
----------------
L
Y
---
F
H
R
R
D
L
R
L
M
A
N
A
I
C
-------
S
A
V
P
V
N
W
V
P
T
G
RTTW
S
I
H
A
G
G
E
W
M
T
T
E
D
M
L
E
V
W
-------
N
R
V
W
IEENEWMEDKTPVEKWS
D
V
P
Y
S
G
K
R
E
D
I
W
C
G
S
L
I
-----
G
T
R
A
R
A
T
W
A
E
N
I
Q
--
V
A
I
N
Q
V
R
S
I
I
G
D
E
K
Y
V
D
Y
M
S
S
L
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
54.32
8%
-29
- C5 -
-
3O7Q
1
FUCP_ECOLI
A:
[22-435]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSYI
I
P
F
A
L
L
C
-
S
L
F
----
F
L
W
A
V
A
N
N
L
N
D
I
L
L
P
Q
----
F
Q
Q
A
F
T
L
-
T
N
F
Q
A
---
G
L
--
I
Q
S
A
F
Y
F
G
--
Y
F
I
I
P
I
P
A
G
I
L
-----
M
K
K
L
S
Y
K
A
G
I
I
T
---
G
L
F
L
Y
A
L
G
--
A
A
L
F
W
P
---------------
A
A
E
I
--
M
--------
N
Y
T
L
F
L
V
G
L
F
I
I
--------
A
A
G
L
G
----
C
-
L
-
E
T
A
A
N
P
F
V
T
V
L
G
--------------
P
E
S
S
G
H
F
R
L
-----------
N
L
-------------
A
Q
T
F
N
S
F
G
-----------
A
I
I
A
V
V
F
G
-----
Q
S
L
I
--
L
S
N
-----
V
P
H
Q
-------------------------
S
Q
D
V
L
D
K
M
S
P
----------
E
Q
L
S
A
Y
K
H
S
--
L
V
-----
L
S
-----
V
Q
T
P
Y
M
I
I
V
A
I
V
L
L
V
A
L
L
I
---
M
L
T
K
F
P
A
L
Q
S
D
N
H
S
--------
D
A
K
--
Q
-------------
G
S
F
--------
S
A
S
L
---------------
S
R
L
--------
A
R
-
I
R
---------------------
H
W
R
W
-----------
A
V
----
L
A
Q
F
C
Y
V
G
A
Q
T
A
C
W
-
S
---------
Y
L
I
------
R
Y
A
----
V
E
E
I
P
G
M
T
A
G
F
A
A
N
Y
L
T
G
T
M
----------------------
V
C
F
F
----------
I
G
R
F
T
G
T
W
L
I
S
R
F
A
P
H
K
-----------
V
L
---
A
A
Y
A
L
I
A
M
A
L
C
--
L
I
S
A
F
----------------
A
G
---
G
H
V
G
L
I
A
L
T
L
C
S
A
F
-------
M
S
I
Q
Y
P
T
I
F
S
L
----
G
I
K
N
L
G
Q
D
T
K
Y
G
S
S
F
I
V
M
-------
T
I
I
------------------
G
G
G
I
V
T
P
V
M
G
F
V
S
D
A
A
G
-----
N
I
P
T
A
E
L
I
P
A
L
C
F
--
A
V
I
F
I
F
A
R
F
--
R
S
Q
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
46
Fugue
53.21
13%
28
- C5 -
-
3W3W
-
IMB3_YEAST
A:
[3-1077]
ALP
E
E
V
N
R
T
L
L
Q
I
V
Q
A
FASD
N
Q
I
R
S
V
A
E
K
A
L
S
EEWITENN
I
E
Y
L
L
T
F
L
A
E
Q
A
A
FSQD
T
T
V
A
A
L
S
A
V
L
F
R
K
L
A
L
K
A
PITHIR
K
E
V
L
A
Q
I
R
S
S
L
L
K
G
F
L
SERA
D
S
I
R
H
K
L
S
D
A
I
A
E
C
VQDDLPAW
P
E
L
L
Q
A
L
I
E
S
L
K
SGN
P
N
F
R
E
S
S
F
R
I
L
T
T
V
P
Y
L
I
T
A
VD
I
N
S
I
L
P
I
F
Q
S
G
F
T
DAS
D
N
V
K
I
A
A
V
T
A
F
V
G
Y
F
K
Q
LPKSEWSKLGIL
L
P
S
L
L
N
S
L
P
R
F
L
D
D
GK
D
D
A
L
A
S
V
F
E
S
L
I
E
L
V
E
L
A
P
-
K
L
F
----
K
D
M
-
F
D
Q
I
I
Q
F
T
D
M
V
I
----
K
N
K
--
D
L
-
E
P
P
A
R
T
T
A
L
E
--
L
L
T
V
F
S
E
N
--
A
P
Q
M
C
K
S
N
Q
N
Y
G
Q
T
L
V
M
V
T
L
I
M
M
T
E
V
S
I
DDD
D
A
A
E
W
I
E
S
--
D
D
T
D
D
E
---------------
E
E
V
T
--
Y
D
H
A
R
Q
A
L
D
R
V
A
L
K
L
G
G
E
Y
L
A
--------
A
P
L
F
Q
--
Y
L
Q
-
Q
-
M
I
T
S
T
E
W
R
E
R
F
A
--------------
A
M
M
A
L
S
S
A
A
-----------
E
G
-------------
C
A
D
V
L
I
G
E
-----------
I
P
K
I
L
D
M
V
-----
I
P
L
I
--
N
D
P
-----
H
P
R
V
-------------------------
Q
Y
G
C
C
N
V
L
G
Q
I
S
T
D
F
S
P
F
I
Q
R
T
A
H
D
R
I
L
P
--
A
L
-----
I
S
K
L
TSE
C
T
S
R
V
Q
T
H
A
A
A
A
L
V
N
F
S
E
F
ASK
D
I
L
E
P
-
Y
L
D
S
L
L
T
N
--------
L
L
V
L
L
Q
-------------
S
N
K
--------
L
Y
V
Q
---------------
E
Q
A
--------
L
T
-
T
I
---------------------
A
F
I
A
-----------
E
A
----
A
K
N
K
F
I
K
Y
Y
D
T
L
M
P
-
L
---------
L
L
N
------
V
L
K
----
V
N
S
V
L
K
G
K
C
M
E
C
A
T
L
I
G
F
A
V
----------------------
G
K
E
K
----------
F
H
E
H
S
Q
E
L
I
S
I
L
V
A
L
Q
N
-----------
S
D
A
L
R
S
Y
L
E
Q
S
W
S
R
I
C
--
R
I
-
L
G
----------------
D
D
---
F
V
P
L
L
P
I
V
I
P
P
L
L
I
-------
T
A
K
A
T
Q
D
V
G
L
I
----
E
E
E
E
A
A
N
F
Q
Q
Y
P
D
W
D
V
V
Q
-------
V
Q
----------------------------
G
K
H
I
A
I
H
T
-----
S
V
L
D
D
K
V
S
A
M
E
L
L
--
Q
S
Y
A
T
L
L
R
----
G
Q
F
A
V
Y
V
K
E
V
M
E
EI
A
L
P
S
L
D
FYLH
D
G
V
R
A
A
G
A
T
L
I
P
I
L
L
S
C
L
L
A
AE
E
L
V
L
L
W
H
K
A
S
S
K
L
I
G
G
L
M
S
EPM
P
E
I
T
Q
V
Y
H
N
S
L
V
N
G
I
K
V
M
GDNCLS
E
D
Q
L
A
A
F
T
K
G
V
S
A
N
L
T
D
T
Y
E
R
M
Q
DRDEYNED
F
T
D
E
D
L
L
D
E
I
N
K
S
I
A
A
V
L
K
T
T
N
GHY
L
K
N
L
E
N
I
W
P
M
I
N
T
F
L
LE
P
I
L
V
I
F
A
L
V
V
I
G
D
L
I
Q
YEQTASMKNAF
I
P
K
V
T
E
C
L
ISPD
A
R
I
R
Q
A
A
S
Y
I
I
G
V
C
A
Q
YAPSTYADVCIPT
L
D
T
L
V
Q
I
V
DGSKLEEN
R
S
S
T
E
N
A
S
A
A
I
A
K
I
L
Y
A
Y
NSNIPD
T
Y
T
A
N
W
F
K
T
LPTITD
K
E
A
A
S
F
N
Y
Q
F
L
S
QVCAQSN
I
S
A
V
V
D
S
V
I
Q
A
L
N
E
RSLT
V
I
S
S
V
K
K
L
L
G
F
L
P
S
S
D
A
M
A
I
F
N
RYP
A
D
I
M
E
K
V
H
K
W
F
41
Fugue
48.03
18%
-136
* C6 *
-
1W09
-
AHSP_HUMAN
A:
[3-94]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
-----
K
A
N
K
--
D
L
I
-----
S
A
G
L
-------------------------
K
E
F
S
V
L
L
N
Q
-----------
Q
V
F
N
D
P
L
V
S
--
E
E
-----
D
M
-----
V
T
V
V
E
D
W
M
N
F
Y
I
N
Y
Y
R
Q
------------------
Q
--------
V
T
G
--
E
------------------------
P
Q
E
R
---------------
D
K
A
--------
L
Q
-
E
L
---------------------
R
Q
E
L
-----------
N
T
----
L
A
N
P
F
L
A
K
Y
R
D
F
L
K
-
S
---------
H
E
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
42.42
16%
-246
- C4 -
-
2KTF
-
POLI_HUMAN
B:
[681-705]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
I
D
----------------
P
Q
---
V
F
Y
E
L
P
E
A
V
Q
K
E
L
L
-------
A
E
W
K
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
38.49
19%
-157
- C4 -
-
2MUL
-
HUWE1_HUMAN
A:
[2966-2997]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
G
V
D
----------------
P
S
---
F
L
A
A
L
P
D
D
I
R
R
E
V
L
-------
Q
N
Q
L
G
I
R
P
P
T
R
----
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
34.67
10%
-176
- C4 -
-
2L0F
-
POLI_HUMAN
B:
[681-709]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
I
D
----------------
P
Q
---
V
F
Y
E
L
A
E
A
V
Q
K
E
L
L
-------
A
E
W
K
R
T
G
S
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
34.19
28%
1
- C4 -
-
5UKK
-
ARBK1_HUMAN
A:
[97-172]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
A
T
E
H
--------
V
Q
G
--
H
-------------
L
G
K
--------
K
Q
V
P
---------------
P
D
L
--------
F
Q
-
P
Y
---------------------
I
E
E
I
-----------
C
Q
N
L
R
G
D
V
F
Q
K
F
I
E
S
D
K
F
T
R
F
C
---------
Q
W
K
------
N
V
-------
E
L
N
I
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
33.65
19%
-66
- C4 -
-
3O39
-
SPY_ECO57
A:
[81-106]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
E
T
Q
---
N
K
--
I
Y
N
I
L
T
P
E
--
Q
K
K
Q
F
N
A
N
F
E
K
-----
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
33.23
9%
36
- C3 -
-
3OKG
-
?
A:
[15-412]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
E
G
P
Y
K
L
P
----
P
G
W
-
R
W
V
R
L
G
E
V
C
L
P
T
E
R
R
D
P
T
K
--
N
P
-
S
T
Y
F
V
---
Y
V
--
D
I
S
A
I
D
S
T
--
V
G
K
I
V
S
P
K
E
I
L
-----
G
Q
H
A
P
S
R
A
R
K
V
I
---
R
S
G
D
V
I
F
A
TT
R
P
Y
L
K
N
---------------
I
A
L
V
--
P
P
D
L
D
G
Q
I
C
S
------
T
G
F
C
V
--------
I
R
A
N
R
--
E
F
A
-
E
-
P
E
F
L
F
H
L
C
R
S
D
F
--------------
I
T
N
Q
L
T
A
S
K
-----------
M
R
-------------
G
T
S
Y
P
A
V
T
-----------
D
N
D
V
Y
N
T
--------
L
I
--
P
L
P
-----
P
----------------------------------------------------------------------------
L
E
E
Q
R
R
I
V
A
K
V
E
A
L
M
E
---
R
V
R
E
V
-
R
R
L
R
A
E
A
Q
--------
K
D
T
--
E
-------------
L
L
M
--------
Q
T
A
L
---------------
A
E
V
--------
F
P
-
H
P
---------------------
G
A
D
L
-----------
P
P
----
G
W
R
W
V
R
L
G
E
V
C
D
I
I
-
M
---------
G
----------------
Q
S
P
P
S
S
T
Y
N
F
E
G
N
G
L
P
F
F
Q
----------------------
G
K
A
D
----------
F
G
D
L
H
P
T
P
R
I
W
C
S
A
P
Q
K
-----------
V
A
R
P
G
D
V
L
I
S
V
R
A
P
V
G
--
S
T
N
V
A
----------------
N
L
A
C
C
I
G
R
G
L
A
A
L
R
P
R
D
S
L
-------
E
R
F
W
L
L
Y
Y
L
H
Y
----
L
E
P
E
L
S
K
A
I
T
K
K
D
L
Q
N
V
F
-------
I
P
L
------------------
P
P
L
E
E
Q
R
R
I
V
A
Y
L
D
Q
I
Q
-----
Q
Q
V
A
A
L
K
R
A
Q
A
E
T
--
E
A
E
L
K
R
L
E
---
Q
A
I
L
D
K
A
F
R
G
D
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
32.50
28%
-3
- C4 -
-
3KRX
-
ARBK1_HUMAN
A:
[125-206]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
A
T
E
H
--------
V
Q
G
--
H
-------------
L
G
K
--------
K
Q
V
P
---------------
P
D
L
--------
F
Q
-
P
Y
---------------------
I
E
E
I
-----------
C
Q
N
L
R
G
D
V
F
Q
K
F
I
E
S
D
K
F
T
R
F
C
---------
Q
W
K
------
N
V
-------
E
L
N
I
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
32.29
28%
-14
- C4 -
-
5HE1
-
ARBK1_HUMAN
A:
[98-179]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
A
T
E
H
--------
V
Q
G
--
H
-------------
L
G
K
--------
K
Q
V
P
---------------
P
D
L
--------
F
Q
-
P
Y
---------------------
I
E
E
I
-----------
C
Q
N
L
RG
D
V
F
Q
K
F
I
E
S
D
K
F
T
R
F
C
---------
Q
W
K
------
N
V
-------
E
L
N
I
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
32.28
28%
-9
- C4 -
-
4MK0
-
ARBK1_HUMAN
A:
[97-165]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
A
T
E
H
--------
V
Q
G
--
H
-------------
L
G
K
--------
K
Q
V
P
---------------
P
D
L
--------
F
Q
-
P
Y
---------------------
I
E
E
I
-----------
C
Q
N
L
RG
D
V
F
Q
K
F
I
E
S
D
K
F
T
R
F
C
---------
Q
W
K
------
N
V
-------
E
L
N
I
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
32.02
31%
-63
- C4 -
-
4UP8
-
?
A:
[249-328]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
F
R
N
----------
E
G
I
D
Q
T
H
N
P
---------------------
E
F
T
T
C
E
F
Y
M
A
Y
A
D
Y
-------
N
-
D
I
M
K
M
T
E
E
L
L
G
N
M
V
K
D
I
T
G
--
G
-------------
S
T
K
--------
L
E
I
K
---------------
D
R
L
--------
M
D
-
I
N
---------------------
N
E
E
D
-----------
I
K
----
M
L
E
K
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
32.00
28%
0
- C4 -
-
4PNK
-
ARBK1_HUMAN
A:
[126-199]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
S
A
T
E
H
--------
V
Q
G
--
H
-------------
L
G
K
--------
K
Q
V
P
---------------
P
D
L
--------
F
Q
-
P
Y
---------------------
I
E
E
I
-----------
C
Q
N
L
RG
D
V
F
Q
K
F
I
E
S
D
K
F
T
R
F
C
---------
Q
W
K
------
N
V
-------
E
L
N
I
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
31.31
38%
-61
- C4 -
-
2IHM
2
DPOLM_MOUSE
A:
[125-186]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
D
E
L
R
E
Q
P
Q
-----
R
L
T
Q
Q
Q
K
A
G
L
Q
Y
Y
--
Q
D
L
S
T
P
V
R
R
--
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------