@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y200: (2018-01-28 )
MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQIDKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPDGTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFDFAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKLVVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHFLGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRLELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPSTIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY
Atome Classification :
(21 SA)
.........10........20........30........40....-....50........60........70........80........90........100..--.....110.......120.......130........140....----...150..----------------------.....160.......170.......180.......190.-......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320...-....330.......340.......350.......360.......370.......380.......390.......400.......410......-----.420.......430.......440....
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
MVKKQI
T
G
E
E
I
K
R
I
I
E
EEN
V
R
F
L
R
L
M
F
T
D
I
L
G
T
I
KNVEV
P
V
S
Q
I
D
-
K
V
L
E
N
KMMFDGSSI
E
G
F
V
R
I
EES
D
M
Y
LYPDLS
T
W
M
I
F
PWESAH
G
K
V
A
R
L
I
C
D
IYNPDGT--PFAGDPR
G
N
L
K
R
A
L
K
D
M
R
D
LGFTSFNL-GPEP
E
F
F
L
F
K
LDEDG----
G
I
T
T
T
LND----------------------KGG
Y
F
DFAPTD
L
G
E
N
C
R
R
D
I
V
L
E
L
E
SL
G
F
E
V
EASHHEVA-PGQ
H
E
I
D
F
K
Y
A
D
V
V
D
ACDN
I
Q
T
F
K
L
V
V
K
T
I
A
R
KHGLHATFMPKPLFGINGSG
M
H
C
N
M
S
L
FNDEG
N
V
F
YDKDG
E
L
E
L
S
E
T
A
Y
H
F
L
G
G
L
L
K
H
A
R
A
Y
TAVCNP
T
V
N
S
Y
K
R
LVPGYEA
P
V
Y
V
A
WSGRNRS
P
L
V
RVP-ESRGL
S
T
R
L
E
L
R
SVDPSA
N
P
Y
L
A
M
A
V
L
L
Q
A
G
L
D
G
I
R
NQITPPAAVD
R
N
I
Y
V
M
D
E
E
ER
E
A
A
H
I
Q
D
L
P
S
T
I
H
N
A
I
K
E
L
R
KDN
V
M
I
D
A
L
G
Q
H
I
F
S
N
-----
F
V
E
A
K
R
L
E
W
A
A
F
R
Q
T
V
S
E
W
E
R
E
Q
Y
LELY
5
PsiBlast_PDB
99.26
71%
0
- C- -
-
4S0R
-
GLN1A_BACSU
A:
[6-447]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
4
PsiBlast_PDB
96.93
71%
-84
- C3 -
-
4LNO
1
GLN1A_BACSU
A:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
21
PsiBlast_CBE
96.39
71%
-84
- C3 -
-
4LNO
2
GLN1A_BACSU
F:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
52
PsiBlast_CBE
96.00
71%
-85
- C3 -
-
4LNI
2
GLN1A_BACSU
B:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
51
PsiBlast_CBE
95.68
71%
-82
- C3 -
-
4LNI
2
GLN1A_BACSU
C:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
63
PsiBlast_CBE
95.65
71%
-83
- C3 -
-
4LNF
1
GLN1A_BACSU
B:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
50
PsiBlast_CBE
95.53
71%
-82
- C3 -
-
4LNI
1
GLN1A_BACSU
D:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
6
PsiBlast_PDB
95.53
71%
-82
- C3 -
-
4LNI
1
GLN1A_BACSU
A:
[2-440]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
---
25
PsiBlast_CBE
95.44
71%
-84
- C3 -
-
4LNO
1
GLN1A_BACSU
B:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
24
PsiBlast_CBE
95.26
71%
-85
- C3 -
-
4LNO
1
GLN1A_BACSU
C:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
22
PsiBlast_CBE
95.06
71%
-82
- C3 -
-
4LNO
1
GLN1A_BACSU
E:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
37
PsiBlast_CBE
94.87
71%
-83
- C3 -
-
4LNK
1
GLN1A_BACSU
F:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
23
PsiBlast_CBE
94.87
71%
-82
- C3 -
-
4LNO
1
GLN1A_BACSU
D:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
2
PsiBlast_PDB
94.50
71%
-81
- C3 -
-
4LNF
1
GLN1A_BACSU
A:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
1
PsiBlast_PDB
94.41
71%
-81
- C3 -
-
4LNK
2
GLN1A_BACSU
A:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
40
PsiBlast_CBE
94.34
71%
-84
- C3 -
-
4LNK
4
GLN1A_BACSU
C:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
62
PsiBlast_CBE
93.88
71%
-82
- C3 -
-
4LNF
1
GLN1A_BACSU
C:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
38
PsiBlast_CBE
93.88
71%
-80
- C3 -
-
4LNK
3
GLN1A_BACSU
E:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
3
PsiBlast_PDB
93.74
71%
-86
- C3 -
-
4LNN
-
GLN1A_BACSU
A:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
----
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
41
PsiBlast_CBE
93.31
71%
-78
- C3 -
-
4LNK
3
GLN1A_BACSU
B:
[2-443]
----
K
Y
T
R
E
D
I
E
K
L
V
K
E
E
N
V
K
Y
I
R
L
Q
F
T
D
I
L
G
T
I
K
N
V
E
I
P
V
S
Q
L
G
-
K
A
L
D
N
K
V
M
F
D
G
S
S
I
E
G
F
V
R
I
E
E
S
D
M
Y
L
Y
P
D
L
N
T
F
V
I
F
P
W
T
A
E
K
G
K
V
A
R
F
I
C
D
I
Y
N
P
D
G
T
--
P
F
E
G
D
P
R
N
N
L
K
R
I
L
K
E
M
E
D
L
G
F
S
D
F
N
L
-
G
P
E
P
E
F
F
L
F
K
L
D
E
K
G
----
E
P
T
L
E
L
N
D
----------------------
K
G
G
Y
F
D
L
A
P
T
D
L
G
E
N
C
R
R
D
I
V
L
E
L
E
E
M
G
F
E
I
E
A
S
H
H
E
V
A
-
P
G
Q
H
E
I
D
F
K
Y
A
G
A
V
R
S
C
D
D
I
Q
T
F
K
L
V
V
K
T
I
A
R
K
H
G
L
H
A
T
F
M
P
K
P
L
F
G
V
N
G
S
G
M
H
C
N
L
S
L
F
K
N
G
V
N
A
F
F
D
E
N
A
D
L
Q
L
S
E
T
A
K
H
F
I
A
G
I
V
K
H
A
T
S
F
T
A
V
T
N
P
T
V
N
S
Y
K
R
L
V
P
G
Y
E
A
P
C
Y
V
A
W
S
A
Q
N
R
S
P
L
I
R
I
P
-
A
S
R
G
I
S
T
R
V
E
V
R
S
V
D
P
A
A
N
P
Y
L
A
L
S
V
L
L
A
A
G
L
D
G
I
K
N
K
L
E
A
P
A
P
I
D
R
N
I
Y
V
M
S
K
E
E
R
M
E
N
G
I
V
D
L
P
A
T
L
A
E
A
L
E
E
F
K
S
N
E
V
M
V
K
A
L
G
E
H
L
F
E
H
-----
F
I
E
A
K
E
I
E
W
D
M
F
R
T
Q
V
H
P
W
E
R
E
Q
Y
M
S
Q
Y
110
PsiBlast_CBE
65.89
40%
9
- C3 -
-
1FPY
29
GLN1B_SALTY
L:
[1-468]
------
S
A
E
H
V
L
T
M
L
N
E
H
E
V
K
F
V
D
L
R
F
T
D
T
K
G
K
E
Q
H
V
T
I
P
A
H
Q
V
N
A
E
F
F
E
E
G
K
M
F
D
G
S
S
I
G
G
W
K
G
I
N
E
S
D
M
V
L
M
P
D
A
S
T
A
V
I
D
P
F
F
A
D
S
T
L
I
I
R
--
C
D
I
L
E
P
-
G
T
LQ
G
Y
D
R
D
P
R
S
I
A
K
R
A
E
D
Y
L
R
A
T
G
I
A
D
T
V
L
F
G
P
E
P
E
F
F
L
F
D
D
I
R
F
G
ASIS
G
S
H
V
A
I
D
D
IEGAWNSSTKYEGGNKGHRPGV
K
G
G
Y
F
P
V
P
P
V
D
S
A
Q
D
I
R
S
E
M
C
L
V
M
E
Q
M
G
L
V
V
E
A
H
H
H
E
V
A
T
A
G
Q
N
E
V
A
T
R
F
N
T
M
T
K
K
A
D
E
I
Q
I
Y
K
Y
V
V
H
N
V
A
H
R
F
G
K
T
A
T
F
M
P
K
P
M
F
G
D
N
G
S
G
M
H
C
H
M
S
L
A
K
N
G
T
N
L
F
-
S
G
D
K
Y
A
G
L
S
E
Q
A
L
Y
Y
I
G
G
V
I
K
H
A
K
A
I
N
A
L
A
N
P
T
T
N
S
Y
K
R
L
V
P
G
Y
E
A
P
V
M
L
A
Y
S
A
R
N
R
S
A
S
I
R
I
P
V
V
A
S
P
K
A
R
R
I
E
V
R
F
P
D
P
A
A
N
P
Y
L
C
F
A
A
L
L
M
A
G
L
D
G
I
K
N
K
I
H
P
G
E
P
M
D
K
N
L
Y
D
L
P
P
E
--
E
A
K
E
I
P
Q
V
A
G
S
L
E
E
A
L
N
A
L
D
L
D
R
E
F
L
K
A
G
G
--
V
F
T
D
EAIDA
Y
I
A
L
R
R
E
E
D
D
R
V
R
M
T
P
H
P
V
E
F
E
L
Y
Y
S
V
-