@TOME V2.3
(Mar 2018)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y2D9: (2018-01-30 )
MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVIVVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADATGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKEILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRSAEMVIEFVKHLV
Atome Classification :
(81 SA)
.........10.......----.20--.-...-...---.30........40........50........60........70........80........90........100.......110.......120.......130-..-.---....140........150.......160.......170.......180.......190.......200.......210.......220.......230
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
M
K
I
G
I
IGA
M
E
E
E
V
K
I
L
R
E
----NLS--E-PLS-WER---A
G
A
L
F
I
S
GSLGN
H
E
V
I
V
V
RS
G
I
G
K
V
L
A
S
I
T
T
S
L
L
I
Q
Q
YG
V
N
M
V
I
NTGSAGGIGEG
L
Q
V
G
D
I
V
ISD
K
V
A
Y
F
DADATGFGYNPGQLPGM
P
L
Y
Y
E
A
S
T
Y
L
R
S
E
M
V
K
A
-
A
K-A---TNLNA-KE
G
L
I
V
TGDTFVD
S
P
D
K
I
K
E
I
L
T
NF
P
E
A
L
A
C
EMEGAAVGQ
T
A
R
QFNI
P
F
L
I
V
R
AMSDTAD
H
S
A
T
Q
S
F
D
E
F
I
E
D
AGK
R
S
A
E
M
V
I
E
F
V
K
H
LV
42
PsiBlast_CBE
95.28
45%
-117
- C1 -
-
1Y6Q
2
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
32
PsiBlast_CBE
95.13
45%
-116
- C1 -
-
4F3C
4
?
B:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
33
PsiBlast_CBE
94.81
45%
-116
- C1 -
-
4F2W
6
?
B:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
97
HHSearch
94.77
46%
-124
- C1 -
-
4F1W
11
?
A:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
44
PsiBlast_CBE
94.62
45%
-116
- C1 -
-
1NC1
1
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
50
PsiBlast_CBE
94.50
45%
-120
- C1 -
-
1Z5O
2
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
N
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
10
PsiBlast_PDB
94.24
45%
-124
- C1 -
-
4F1W
11
?
A:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
45
PsiBlast_CBE
94.23
45%
-129
- C1 -
-
1JYS
1
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
----
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
11
PsiBlast_PDB
94.01
45%
-114
- C1 -
-
4F2P
5
?
A:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
39
PsiBlast_CBE
93.91
45%
-132
- C1 -
-
1Z5P
4
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
96
HHSearch
93.44
47%
-110
- C1 -
-
3BL6
1
MTNN_STAAM
A:
[2-230]
M
M
I
G
I
I
G
A
M
E
E
E
V
T
I
L
K
N
----
K
L
T
--
Q
-
L
S
E
-
I
S
V
---
A
H
V
K
F
Y
T
G
I
L
K
D
R
E
V
V
I
T
Q
S
G
I
G
K
V
N
A
A
I
S
T
T
L
L
I
N
K
F
K
P
D
V
I
I
N
T
G
S
A
G
A
L
D
E
S
L
N
V
G
D
V
L
I
S
D
D
V
K
Y
H
D
A
D
A
T
A
F
G
Y
E
Y
G
Q
I
P
Q
M
P
V
A
F
Q
S
S
K
P
L
I
E
K
V
S
Q
V
-
V
Q
-
Q
---
Q
Q
L
T
A
-
K
V
G
L
I
V
S
G
D
S
F
I
G
S
V
E
Q
R
Q
K
I
K
K
A
F
P
N
A
M
A
V
E
M
E
A
T
A
I
A
Q
T
C
Y
Q
F
N
V
P
F
V
V
V
R
A
V
S
D
L
A
N
G
E
A
E
M
S
F
E
A
F
L
E
K
A
A
V
S
S
S
Q
T
V
E
A
L
V
S
Q
L
-
2
PsiBlast_PDB
93.44
47%
-110
- C1 -
-
3BL6
1
MTNN_STAAM
A:
[2-230]
M
M
I
G
I
I
G
A
M
E
E
E
V
T
I
L
K
N
----
K
L
T
--
Q
-
L
S
E
-
I
S
V
---
A
H
V
K
F
Y
T
G
I
L
K
D
R
E
V
V
I
T
Q
S
G
I
G
K
V
N
A
A
I
S
T
T
L
L
I
N
K
F
K
P
D
V
I
I
N
T
G
S
A
G
A
L
D
E
S
L
N
V
G
D
V
L
I
S
D
D
V
K
Y
H
D
A
D
A
T
A
F
G
Y
E
Y
G
Q
I
P
Q
M
P
V
A
F
Q
S
S
K
P
L
I
E
K
V
S
Q
V
-
V
Q
-
Q
---
Q
Q
L
T
A
-
K
V
G
L
I
V
S
G
D
S
F
I
G
S
V
E
Q
R
Q
K
I
K
K
A
F
P
N
A
M
A
V
E
M
E
A
T
A
I
A
Q
T
C
Y
Q
F
N
V
P
F
V
V
V
R
A
V
S
D
L
A
N
G
E
A
E
M
S
F
E
A
F
L
E
K
A
A
V
S
S
S
Q
T
V
E
A
L
V
S
Q
L
-
48
PsiBlast_CBE
93.40
45%
-118
- C1 -
-
1Z5N
3
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
Q
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
40
PsiBlast_CBE
93.39
45%
-116
- C1 -
-
1Y6R
2
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
47
PsiBlast_CBE
93.38
45%
-116
- C1 -
-
4WKC
2
MTNN_ECOLI
A:
[1-229]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
43
PsiBlast_CBE
93.30
45%
-113
- C1 -
-
1NC3
1
MTNN_ECOLI
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
13
PsiBlast_PDB
93.25
45%
-116
- C1 -
-
4F3C
4
?
A:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
49
PsiBlast_CBE
93.23
45%
-122
- C1 -
-
1Z5N
2
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
Q
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
36
PsiBlast_CBE
93.23
45%
-116
- C1 -
-
3O4V
7
MTNN_ECOLI
B:
[3-231]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
51
PsiBlast_CBE
93.20
45%
-118
- C1 -
-
1Z5O
2
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
N
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
37
PsiBlast_CBE
92.70
45%
-118
- C1 -
-
3DF9
2
MTNN_ECO57
B:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
35
PsiBlast_CBE
92.51
45%
-115
- C1 -
-
4F1W
8
?
B:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
101
HHSearch
92.48
45%
-124
- C1 -
-
4G41
1
?
B:
[6-234]
M
K
I
G
I
I
A
A
M
E
E
E
L
S
L
L
L
A
----
N
L
L
--
D
-
A
Q
E
-
H
Q
V
---
L
S
K
T
Y
Y
T
G
R
F
G
K
H
E
L
I
L
V
Q
S
G
V
G
K
V
M
S
A
M
T
V
A
I
L
V
E
H
F
K
A
Q
A
I
I
N
T
G
S
A
G
A
V
A
S
H
L
A
I
G
D
V
V
V
A
D
R
L
V
Y
H
D
V
D
A
T
A
F
G
Y
A
Y
G
Q
M
A
G
Q
P
L
Y
Y
D
C
D
P
Q
F
V
A
I
F
K
Q
V
-
L
K
-
H
---
E
K
T
N
G
-
Q
V
G
L
I
A
T
G
D
S
F
V
A
G
Q
D
K
I
D
Q
I
K
T
A
F
S
N
V
L
A
V
E
M
E
G
A
A
I
A
Q
A
A
H
T
A
G
K
P
F
I
V
V
R
A
M
S
D
T
A
A
H
D
A
N
I
T
F
D
Q
F
I
I
E
A
G
K
R
S
A
Q
I
L
M
T
F
L
E
N
L
-
52
PsiBlast_CBE
92.48
45%
-124
- C1 -
-
4G41
1
?
B:
[6-234]
M
K
I
G
I
I
A
A
M
E
E
E
L
S
L
L
L
A
----
N
L
L
--
D
-
A
Q
E
-
H
Q
V
---
L
S
K
T
Y
Y
T
G
R
F
G
K
H
E
L
I
L
V
Q
S
G
V
G
K
V
M
S
A
M
T
V
A
I
L
V
E
H
F
K
A
Q
A
I
I
N
T
G
S
A
G
A
V
A
S
H
L
A
I
G
D
V
V
V
A
D
R
L
V
Y
H
D
V
D
A
T
A
F
G
Y
A
Y
G
Q
M
A
G
Q
P
L
Y
Y
D
C
D
P
Q
F
V
A
I
F
K
Q
V
-
L
K
-
H
---
E
K
T
N
G
-
Q
V
G
L
I
A
T
G
D
S
F
V
A
G
Q
D
K
I
D
Q
I
K
T
A
F
S
N
V
L
A
V
E
M
E
G
A
A
I
A
Q
A
A
H
T
A
G
K
P
F
I
V
V
R
A
M
S
D
T
A
A
H
D
A
N
I
T
F
D
Q
F
I
I
E
A
G
K
R
S
A
Q
I
L
M
T
F
L
E
N
L
-
41
PsiBlast_CBE
92.40
45%
-116
- C1 -
-
1Y6R
2
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
38
PsiBlast_CBE
92.33
45%
-119
- C1 -
-
3DF9
2
MTNN_ECO57
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
46
PsiBlast_CBE
92.25
45%
-119
- C1 -
-
4YML
1
MTNN_ECOLI
A:
[1-229]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
12
PsiBlast_PDB
92.05
45%
-115
- C1 -
-
4F2W
4
?
A:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
34
PsiBlast_CBE
92.04
45%
-117
- C1 -
-
4F2P
4
?
B:
[17-245]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
D
--
N
-
R
Q
T
-
I
T
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
T
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
S
C
-
I
R
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
D
A
V
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
T
L
M
V
E
T
L
V
Q
K
L
-
20
PsiBlast_PDB
92.03
45%
-118
- C1 -
-
1Y6Q
2
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
9
PsiBlast_PDB
91.88
44%
-120
- C1 -
-
4G89
2
MTNN_KLEP7
A:
[6-234]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
T
I
---
G
G
S
E
I
Y
T
G
Q
L
H
G
V
D
V
A
L
L
K
S
G
I
G
K
V
A
A
A
M
G
A
T
L
L
L
E
R
C
Q
P
D
V
I
I
N
T
G
S
A
G
G
L
A
S
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
E
K
L
V
A
A
A
E
S
C
-
I
K
-
A
---
L
D
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
E
E
F
L
A
V
A
A
R
Q
S
T
L
M
V
E
N
L
V
Q
N
L
-
104
HHSearch
91.82
46%
-116
- C1 -
-
3O4V
5
MTNN_ECOLI
A:
[3-231]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
110
HHSearch
91.62
46%
-85
- C1 -
-
5UE1
3
MTNN_VIBF1
A:
[4-233]
M
K
I
G
I
I
G
A
M
E
Q
E
V
A
I
L
K
D
----
K
I
E
--
G
-
L
S
T
-
V
T
K
---
A
G
C
T
F
Y
T
G
T
L
N
G
A
D
V
V
L
L
Q
S
G
I
G
K
V
A
A
A
V
G
T
T
L
L
I
A
E
H
N
V
D
V
V
L
N
T
G
S
A
G
G
F
D
S
S
L
N
L
G
D
V
V
I
S
T
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
M
G
Q
M
A
Q
Q
P
A
A
F
I
A
D
E
K
L
I
T
T
A
E
Q
A
-
L
T
-
E
M--
S
D
K
H
A
-
V
R
G
L
I
C
T
G
D
V
F
V
C
T
P
E
R
Q
E
F
I
R
T
H
F
P
S
V
I
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
N
T
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
M
S
F
D
E
F
L
P
L
A
A
Q
S
S
S
E
M
V
L
N
M
V
T
L
L
-
19
PsiBlast_PDB
91.53
45%
-117
- C1 -
-
1NC1
1
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
15
PsiBlast_PDB
91.28
45%
-116
- C1 -
-
3O4V
5
MTNN_ECOLI
A:
[3-231]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
17
PsiBlast_PDB
91.26
45%
-132
- C1 -
-
1JYS
1
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
----
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
18
PsiBlast_PDB
91.25
45%
-117
- C1 -
-
1NC3
1
MTNN_ECOLI
A:
[11-239]
M
K
I
G
I
I
G
A
M
E
E
E
V
T
L
L
R
D
----
K
I
E
--
N
-
R
Q
T
-
I
S
L
---
G
G
C
E
I
Y
T
G
Q
L
N
G
T
E
V
A
L
L
K
S
G
I
G
K
V
A
A
A
L
G
A
T
L
L
L
E
H
C
K
P
D
V
I
I
N
T
G
S
A
G
G
L
A
P
T
L
K
V
G
D
I
V
V
S
D
E
A
R
Y
H
D
A
D
V
T
A
F
G
Y
E
Y
G
Q
L
P
G
C
P
A
G
F
K
A
D
D
K
L
I
A
A
A
E
A
C
-
I
A
-
E
---
L
N
L
N
A
-
V
R
G
L
I
V
S
G
D
A
F
I
N
G
S
V
G
L
A
K
I
R
H
N
F
P
Q
A
I
A
V
E
M
E
A
T
A
I
A
H
V
C
H
N
F
N
V
P
F
V
V
V
R
A
I
S
D
V
A
D
Q
Q
S
H
L
S
F
D
E
F
L
A
V
A
A
K
Q
S
S
L
M
V
E
S
L
V
Q
K
L
-
8
PsiBlast_PDB
89.87
46%
-79
- C1 -
-
4WKB
2
MTNN_VIBC3
A:
[1-230]
M
K
I
G
I
I
G
A
M
Q
Q
E
V
A
I
L
K
D
----
L
I
E
--
D
-
V
Q
E
-
V
N
Q
---
A
G
C
T
F
Y
S
G
Q
I
Q
G
V
D
V
V
L
L
Q
S
G
I
G
K
V
S
A
A
L
G
T
A
L
L
I
S
Q
Y
A
P
D
V
V
I
N
T
G
S
A
G
G
F
D
A
S
L
N
V
G
D
V
V
I
S
S
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
I
G
Q
M
A
G
Q
P
A
A
F
K
A
D
E
K
L
M
T
V
A
E
Q
A
L
A
Q
-
L
---
P
N
T
H
A
-
V
R
G
L
I
C
T
G
D
A
F
V
C
T
A
E
R
Q
Q
F
I
R
Q
H
F
P
S
V
V
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
L
S
F
E
E
F
L
P
L
A
A
K
S
S
S
A
M
V
L
K
M
V
E
L
L
-
4
PsiBlast_PDB
88.99
46%
-119
- C1 -
-
3MMS
3
?
A:
[1-229]
M
K
I
G
I
I
A
A
M
P
E
E
L
A
Y
L
V
Q
----
H
L
D
--
N
-
A
Q
E
-
Q
V
V
---
L
G
N
T
Y
H
T
G
T
I
V
S
H
E
V
V
L
V
E
S
G
I
G
K
V
M
S
A
M
S
V
A
I
L
A
V
H
F
Q
V
D
A
L
I
N
T
G
S
A
G
A
V
A
E
G
I
A
V
G
D
V
V
I
A
D
K
L
A
Y
H
D
V
D
V
T
A
F
G
Y
A
Y
G
Q
M
A
Q
Q
P
L
Y
F
E
S
D
K
T
F
V
A
Q
I
Q
E
S
-
L
--------
Q
N
W
-
H
L
G
L
I
A
T
G
D
S
F
V
A
G
N
D
K
I
E
A
I
K
S
H
F
P
E
V
L
A
V
E
M
E
G
A
A
I
A
Q
A
A
H
A
L
N
L
P
V
L
V
I
R
A
M
S
D
N
A
N
H
E
A
N
I
F
F
D
E
F
I
I
E
A
G
R
R
S
A
Q
V
L
L
A
F
L
K
A
L
-
5
PsiBlast_PDB
88.93
45%
-84
- C1 -
-
5UE1
3
MTNN_VIBF1
A:
[4-233]
M
K
I
G
I
I
G
A
M
E
Q
E
V
A
I
L
K
D
----
K
I
E
--
G
-
L
S
T
-
V
T
K
---
A
G
C
T
F
Y
T
G
T
L
N
G
A
D
V
V
L
L
Q
S
G
I
G
K
V
A
A
A
V
G
T
T
L
L
I
A
E
H
N
V
D
V
V
L
N
T
G
S
A
G
G
F
D
S
S
L
N
L
G
D
V
V
I
S
T
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
M
G
Q
M
A
Q
Q
P
A
A
F
I
A
D
E
K
L
I
T
T
A
E
Q
A
L
T
E
-
M
---
S
D
K
H
A
-
V
R
G
L
I
C
T
G
D
V
F
V
C
T
P
E
R
Q
E
F
I
R
T
H
F
P
S
V
I
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
N
T
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
M
S
F
D
E
F
L
P
L
A
A
Q
S
S
S
E
M
V
L
N
M
V
T
L
L
-
28
PsiBlast_CBE
88.73
46%
-79
- C1 -
-
3DP9
2
MTNN_VIBCH
C:
[1-230]
M
K
I
G
I
I
G
A
M
Q
Q
E
V
A
I
L
K
D
----
L
I
E
--
D
-
V
Q
E
-
V
N
Q
---
A
G
C
T
F
Y
S
G
Q
I
Q
G
V
D
V
V
L
L
Q
S
G
I
G
K
V
S
A
A
L
G
T
A
L
L
I
S
Q
Y
A
P
D
V
V
I
N
T
G
S
A
G
G
F
D
A
S
L
N
V
G
D
V
V
I
S
S
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
I
G
Q
M
A
G
Q
P
A
A
F
K
A
D
E
K
L
M
T
V
A
E
Q
A
L
A
Q
-
L
---
P
N
T
H
A
-
V
R
G
L
I
C
T
G
D
A
F
V
C
T
A
E
R
Q
Q
F
I
R
Q
H
F
P
S
V
V
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
L
S
F
E
E
F
L
P
L
A
A
K
S
S
S
A
M
V
L
K
M
V
E
L
L
-
29
PsiBlast_CBE
88.46
46%
-77
- C1 -
-
4WKB
2
MTNN_VIBC3
B:
[1-230]
M
K
I
G
I
I
G
A
M
Q
Q
E
V
A
I
L
K
D
----
L
I
E
--
D
-
V
Q
E
-
V
N
Q
---
A
G
C
T
F
Y
S
G
Q
I
Q
G
V
D
V
V
L
L
Q
S
G
I
G
K
V
S
A
A
L
G
T
A
L
L
I
S
Q
Y
A
P
D
V
V
I
N
T
G
S
A
G
G
F
D
A
S
L
N
V
G
D
V
V
I
S
S
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
I
G
Q
M
A
G
Q
P
A
A
F
K
A
D
E
K
L
M
T
V
A
E
Q
A
L
A
Q
-
L
---
P
N
T
H
A
-
V
R
G
L
I
C
T
G
D
A
F
V
C
T
A
E
R
Q
Q
F
I
R
Q
H
F
P
S
V
V
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
L
S
F
E
E
F
L
P
L
A
A
K
S
S
S
A
M
V
L
K
M
V
E
L
L
-
26
PsiBlast_CBE
88.09
45%
-81
- C1 -
-
5UE1
3
MTNN_VIBF1
B:
[4-233]
M
K
I
G
I
I
G
A
M
E
Q
E
V
A
I
L
K
D
----
K
I
E
--
G
-
L
S
T
-
V
T
K
---
A
G
C
T
F
Y
T
G
T
L
N
G
A
D
V
V
L
L
Q
S
G
I
G
K
V
A
A
A
V
G
T
T
L
L
I
A
E
H
N
V
D
V
V
L
N
T
G
S
A
G
G
F
D
S
S
L
N
L
G
D
V
V
I
S
T
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
M
G
Q
M
A
Q
Q
P
A
A
F
I
A
D
E
K
L
I
T
T
A
E
Q
A
L
T
E
-
M
---
S
D
K
H
A
-
V
R
G
L
I
C
T
G
D
V
F
V
C
T
P
E
R
Q
E
F
I
R
T
H
F
P
S
V
I
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
N
T
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
M
S
F
D
E
F
L
P
L
A
A
Q
S
S
S
E
M
V
L
N
M
V
T
L
L
-
6
PsiBlast_PDB
87.63
46%
-77
- C1 -
-
4X24
3
MTNN_VIBC3
A:
[1-230]
M
K
I
G
I
I
G
A
M
Q
Q
E
V
A
I
L
K
D
----
L
I
E
--
D
-
V
Q
E
-
V
N
Q
---
A
G
C
T
F
Y
S
G
Q
I
Q
G
V
D
V
V
L
L
Q
S
G
I
G
K
V
S
A
A
L
G
T
A
L
L
I
S
Q
Y
A
P
D
V
V
I
N
T
G
S
A
G
G
F
D
A
S
L
N
V
G
D
V
V
I
S
S
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
I
G
Q
M
P
G
Q
P
A
A
F
K
A
D
E
K
L
M
T
V
A
E
Q
A
L
A
Q
-
L
---
P
N
T
H
A
-
V
R
G
L
I
C
T
G
D
A
F
I
C
T
A
E
G
Q
Q
F
I
R
Q
H
F
P
S
V
V
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
L
S
F
E
E
F
L
P
L
A
A
K
S
S
S
A
M
V
L
K
M
V
E
L
L
-
27
PsiBlast_CBE
86.94
46%
-79
- C1 -
-
4X24
2
MTNN_VIBC3
B:
[1-230]
M
K
I
G
I
I
G
A
M
Q
Q
E
V
A
I
L
K
D
----
L
I
E
--
D
-
V
Q
E
-
V
N
Q
---
A
G
C
T
F
Y
S
G
Q
I
Q
G
V
D
V
V
L
L
Q
S
G
I
G
K
V
S
A
A
L
G
T
A
L
L
I
S
Q
Y
A
P
D
V
V
I
N
T
G
S
A
G
G
F
D
A
S
L
N
V
G
D
V
V
I
S
S
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
I
G
Q
M
P
G
Q
P
A
A
F
K
A
D
E
K
L
M
T
V
A
E
Q
A
L
A
Q
-
L
---
P
N
T
H
A
-
V
R
G
L
I
C
T
G
D
A
F
I
C
T
A
E
G
Q
Q
F
I
R
Q
H
F
P
S
V
V
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
L
S
F
E
E
F
L
P
L
A
A
K
S
S
S
A
M
V
L
K
M
V
E
L
L
-
108
HHSearch
86.48
43%
-106
- C1 -
-
4QEZ
2
MTNN_BACAN
C:
[2-230]
-
R
I
A
V
I
G
A
M
E
E
E
V
R
I
L
R
D
----
K
L
E
--
Q
-
A
E
T
-
E
T
V
---
A
G
C
E
F
T
K
G
Q
L
A
G
H
E
V
I
L
L
K
S
G
I
G
K
V
N
A
A
M
S
T
T
I
L
L
E
R
Y
K
P
E
K
V
I
N
T
G
S
A
G
G
F
H
H
S
L
N
V
G
D
V
V
I
S
T
E
V
R
H
H
D
V
D
V
T
A
F
N
Y
E
Y
G
Q
V
P
G
M
P
P
G
F
K
A
D
E
A
L
V
A
L
A
E
K
C
-
M
Q
--------
Q
V
-
V
K
G
M
I
A
T
G
D
S
F
M
S
D
P
N
R
V
A
A
I
R
D
K
F
E
N
L
Y
A
V
E
M
E
A
A
A
V
A
Q
V
C
H
Q
Y
E
V
P
F
V
I
I
R
A
L
S
D
I
A
G
K
E
S
N
V
S
F
D
Q
F
L
D
Q
A
A
L
H
S
T
N
F
I
V
K
V
L
E
E
L
-
7
PsiBlast_PDB
86.37
46%
-79
- C1 -
-
3DP9
2
MTNN_VIBCH
A:
[2-230]
-
K
I
G
I
I
G
A
M
Q
Q
E
V
A
I
L
K
D
----
L
I
E
--
D
-
V
Q
E
-
V
N
Q
---
A
G
C
T
F
Y
S
G
Q
I
Q
G
V
D
V
V
L
L
Q
S
G
I
G
K
V
S
A
A
L
G
T
A
L
L
I
S
Q
Y
A
P
D
V
V
I
N
T
G
S
A
G
G
F
D
A
S
L
N
V
G
D
V
V
I
S
S
E
V
R
H
H
D
A
D
V
T
A
F
G
Y
E
I
G
Q
M
A
G
Q
P
A
A
F
K
A
D
E
K
L
M
T
V
A
E
Q
A
L
A
Q
-
L
---
P
N
T
H
A
-
V
R
G
L
I
C
T
G
D
A
F
V
C
T
A
E
R
Q
Q
F
I
R
Q
H
F
P
S
V
V
A
V
E
M
E
A
S
A
I
A
Q
T
C
H
Q
F
K
V
P
F
V
V
V
R
A
I
S
D
V
A
D
K
E
S
P
L
S
F
E
E
F
L
P
L
A
A
K
S
S
S
A
M
V
L
K
M
V
E
L
L
-
107
HHSearch
83.75
43%
-106
* C1 *
-
4QEZ
2
MTNN_BACAN
A:
[2-230]
-
R
I
A
V
I
G
A
M
E
E
E
V
R
I
L
R
D
----
K
L
E
--
Q
-
A
E
T
-
E
T
V
---
A
G
C
E
F
T
K
G
Q
L
A
G
H
E
V
I
L
L
K
S
G
I
G
K
V
N
A
A
M
S
T
T
I
L
L
E
R
Y
K
P
E
K
V
I
N
T
G
S
A
G
G
F
H
H
S
L
N
V
G
D
V
V
I
S
T
E
V
R
H
H
D
V
D
V
T
A
F
N
Y
E
Y
G
Q
V
P
G
M
P
P
G
F
K
A
D
E
A
L
V
A
L
A
E
K
C
-
M
Q
---------
V
-
V
K
G
M
I
A
T
G
D
S
F
M
S
D
P
N
R
V
A
A
I
R
D
K
F
E
N
L
Y
A
V
E
M
E
A
A
A
V
A
Q
V
C
H
Q
Y
E
V
P
F
V
I
I
R
A
L
S
D
I
A
G
K
E
S
N
V
S
F
D
Q
F
L
D
Q
A
A
L
H
S
T
N
F
I
V
K
V
L
E
E
L
-
113
HHSearch
82.94
43%
-66
- C1 -
-
3EEI
2
?
B:
[4-232]
K
T
V
A
V
I
G
A
M
E
Q
E
I
E
L
L
R
E
----
M
M
E
--
N
-
V
K
A
-
V
S
F
---
G
R
F
S
A
Y
E
G
E
L
A
G
K
R
M
V
L
A
L
S
G
I
G
K
V
N
A
A
V
A
T
A
W
I
I
R
E
F
A
A
D
C
V
I
N
T
G
S
A
G
G
L
G
K
G
L
K
V
G
D
V
V
I
G
T
E
T
A
H
H
D
V
D
V
T
A
F
G
Y
A
W
G
Q
V
P
Q
L
P
A
R
F
A
S
D
G
I
L
I
E
A
A
K
R
A
-
A
R
T
F
---
E
G
A
A
V
-
E
Q
G
L
I
V
S
G
D
R
F
V
H
S
S
E
G
V
A
E
I
R
K
H
F
P
E
V
K
A
V
E
M
E
A
A
A
I
A
Q
T
C
H
Q
L
E
T
P
F
V
I
I
R
A
V
S
D
S
A
D
E
K
A
D
I
S
F
D
E
F
L
K
T
A
A
A
N
S
A
K
M
V
A
E
I
V
K
S
--
54
PsiBlast_CBE
82.00
43%
-98
- C1 -
-
4QEZ
2
MTNN_BACAN
C:
[2-225]
-
R
I
A
V
I
G
A
M
E
E
E
V
R
I
L
R
D
----
K
L
E
--
Q
-
A
E
T
-
E
T
V
---
A
G
C
E
F
T
K
G
Q
L
A
G
H
E
V
I
L
L
K
S
G
I
G
K
V
N
A
A
M
S
T
T
I
L
L
E
R
Y
K
P
E
K
V
I
N
T
G
S
A
G
G
F
H
H
S
L
N
V
G
D
V
V
I
S
T
E
V
R
H
H
D
V
D
V
T
A
F
N
Y
E
Y
G
Q
V
P
G
M
P
P
G
F
K
A
D
E
A
L
V
A
L
A
E
K
C
-
M
Q
--------
Q
V
-
V
K
G
M
I
A
T
G
D
S
F
M
S
D
P
N
R
V
A
A
I
R
D
K
F
E
N
L
Y
A
V
E
M
E
A
A
A
V
A
Q
V
C
H
Q
Y
E
V
P
F
V
I
I
R
A
L
S
D
I
A
G
K
E
S
N
V
S
F
D
Q
F
L
D
Q
A
A
L
H
S
T
N
F
I
V
K
------
98
HHSearch
81.35
36%
-110
- C1 -
-
4JWT
5
?
A:
[23-250]
M
K
I
A
I
M
G
A
M
P
E
E
I
S
P
I
L
E
----
K
I
G
--
S
-
Y
K
S
-
T
S
Y
---
A
G
N
K
Y
Y
E
A
T
Y
Q
G
V
E
L
V
I
A
Y
S
K
I
G
K
V
F
S
A
L
S
A
A
T
M
I
E
H
F
G
A
T
K
L
L
F
S
G
V
A
G
A
I
S
T
N
L
K
V
G
D
L
I
V
A
T
K
L
S
Q
H
D
L
D
I
T
A
F
G
H
P
Y
G
Y
V
P
E
G
S
V
F
V
E
A
D
K
D
M
I
E
L
S
K
K
V
-
A
L
-
E
---
M
G
K
S
V
-
Q
E
G
I
I
A
T
G
D
Q
F
V
A
N
E
E
R
K
N
W
I
G
T
T
F
-
G
A
D
A
L
E
M
E
G
G
S
V
G
V
V
C
N
A
L
N
I
P
F
F
I
L
R
S
I
S
D
A
A
D
M
D
A
S
F
S
F
D
E
F
L
E
S
S
A
K
E
S
A
E
F
I
M
K
M
V
D
E
L
-
100
HHSearch
81.10
37%
-116
- C1 -
-
4JOS
5
?
B:
[24-250]
K
K
I
A
I
L
G
A
M
E
I
E
I
Q
P
I
L
Q
----
K
L
E
--
K
-
Y
E
T
-
V
E
Y
---
A
N
N
K
Y
Y
V
A
N
Y
N
G
I
E
L
V
V
A
Y
S
K
I
G
K
V
F
S
S
L
T
A
T
I
M
I
E
H
F
G
V
D
A
L
L
F
T
G
V
A
G
G
L
Q
-
D
L
Q
V
G
D
M
I
A
A
T
A
T
V
Q
H
D
V
D
I
T
A
F
G
Y
P
Y
G
K
I
P
I
S
E
V
E
I
A
T
S
A
R
I
L
E
Q
A
K
V
I
-
A
K
-
E
---
L
N
L
N
L
-
H
T
G
V
I
A
T
G
D
Q
F
V
H
S
A
E
R
K
D
F
V
V
K
E
F
-
D
A
K
A
I
E
M
E
G
A
S
V
N
L
I
C
N
E
M
N
I
P
S
F
I
L
R
S
I
S
D
T
A
D
G
D
A
P
D
N
F
D
E
F
A
K
M
A
A
N
R
S
A
D
F
V
M
K
L
V
D
R
I
-
109
HHSearch
80.61
44%
-54
- C1 -
-
5DK6
2
MTNN_COLP3
A:
[23-257]
M
K
A
G
I
I
G
A
M
E
P
E
V
A
I
L
K
E
----
K
L
T
--
D
-
A
K
S
-
T
E
H
---
A
G
Y
T
F
H
Q
G
Q
L
D
G
S
D
V
V
I
V
Q
S
G
I
G
K
V
A
A
A
L
A
T
A
I
L
I
D
R
F
Q
V
D
Y
V
V
N
T
G
S
A
G
G
F
D
A
S
L
K
V
G
D
I
V
V
S
S
E
V
R
Y
H
D
V
D
L
T
A
F
G
Y
E
I
G
Q
L
P
A
N
P
A
A
F
M
P
H
D
D
L
V
A
A
A
K
K
G
-
I
E
-
Q
LSQ-
N
I
K
A
-
V
T
G
L
I
T
T
G
D
T
F
M
T
K
E
E
D
V
A
K
A
R
A
N
F
P
T
M
A
A
V
E
M
E
G
A
A
I
A
Q
A
C
L
Q
L
K
T
P
F
V
V
I
R
S
L
S
D
I
A
G
K
E
S
P
H
T
F
E
E
Y
L
E
T
A
A
V
N
S
S
Q
L
V
L
N
M
L
G
Q
L
-
55
PsiBlast_CBE
79.45
43%
-97
- C1 -
-
4QEZ
2
MTNN_BACAN
B:
[2-225]
-
R
I
A
V
I
G
A
M
E
E
E
V
R
I
L
R
D
----
K
L
E
--
Q
-
A
E
T
-
E
T
V
---
A
G
C
E
F
T
K
G
Q
L
A
G
H
E
V
I
L
L
K
S
G
I
G
K
V
N
A
A
M
S
T
T
I
L
L
E
R
Y
K
P
E
K
V
I
N
T
G
S
A
G
G
F
H
H
S
L
N
V
G
D
V
V
I
S
T
E
V
R
H
H
D
V
D
V
T
A
F
N
Y
E
Y
G
Q
V
P
G
M
P
P
G
F
K
A
D
E
A
L
V
A
L
A
E
K
C
-
M
Q
--------
Q
V
-
V
K
G
M
I
A
T
G
D
S
F
M
S
D
P
N
R
V
A
A
I
R
D
K
F
E
N
L
Y
A
V
E
M
E
A
A
A
V
A
Q
V
C
H
Q
Y
E
V
P
F
V
I
I
R
A
L
S
D
I
A
G
K
E
S
N
V
S
F
D
Q
F
L
D
Q
A
A
L
H
S
T
N
F
I
V
K
------
56
PsiBlast_CBE
78.63
43%
-98
- C1 -
-
4QEZ
2
MTNN_BACAN
A:
[2-225]
-
R
I
A
V
I
G
A
M
E
E
E
V
R
I
L
R
D
----
K
L
E
--
Q
-
A
E
T
-
E
T
V
---
A
G
C
E
F
T
K
G
Q
L
A
G
H
E
V
I
L
L
K
S
G
I
G
K
V
N
A
A
M
S
T
T
I
L
L
E
R
Y
K
P
E
K
V
I
N
T
G
S
A
G
G
F
H
H
S
L
N
V
G
D
V
V
I
S
T
E
V
R
H
H
D
V
D
V
T
A
F
N
Y
E
Y
G
Q
V
P
G
M
P
P
G
F
K
A
D
E
A
L
V
A
L
A
E
K
C
-
M
Q
---------
V
-
V
K
G
M
I
A
T
G
D
S
F
M
S
D
P
N
R
V
A
A
I
R
D
K
F
E
N
L
Y
A
V
E
M
E
A
A
A
V
A
Q
V
C
H
Q
Y
E
V
P
F
V
I
I
R
A
L
S
D
I
A
G
K
E
S
N
V
S
F
D
Q
F
L
D
Q
A
A
L
H
S
T
N
F
I
V
K
------
58
PsiBlast_CBE
73.12
44%
-12
- C1 -
-
3EEI
2
?
A:
[6-233]
--
V
A
V
I
G
A
M
E
Q
E
I
E
L
L
R
E
----
M
M
E
N
V
K
-
A
V
S
-
F
G
R
---
F
S
A
Y
--
E
G
E
L
A
G
K
R
M
V
L
A
L
S
G
I
G
K
V
N
A
A
V
A
T
A
W
I
I
R
E
F
A
A
D
C
V
I
N
T
G
S
A
G
G
L
G
K
G
L
K
V
G
D
V
V
I
G
T
E
T
A
H
H
D
V
D
V
T
A
F
G
Y
A
W
G
Q
V
P
Q
L
P
A
R
F
A
S
D
G
I
L
I
E
A
A
K
R
A
-
A
R
-
T
---
F
E
G
A
A
V
E
Q
G
L
I
V
S
G
D
R
F
V
H
S
S
E
G
V
A
E
I
R
K
H
F
P
E
V
K
A
V
E
M
E
A
A
A
I
A
Q
T
C
H
Q
L
E
T
P
F
V
I
I
R
A
V
S
D
S
A
D
E
K
A
D
I
S
F
D
E
F
L
K
T
A
A
A
N
S
A
K
M
V
A
E
I
V
K
S
L
-
57
PsiBlast_CBE
73.03
44%
-12
- C1 -
-
3EEI
2
?
B:
[6-233]
--
V
A
V
I
G
A
M
E
Q
E
I
E
L
L
R
E
----
M
M
E
NV
K
-
A
V
S
-
F
G
R
---
F
S
A
Y
--
E
G
E
L
A
G
K
R
M
V
L
A
L
S
G
I
G
K
V
N
A
A
V
A
T
A
W
I
I
R
E
F
A
A
D
C
V
I
N
T
G
S
A
G
G
L
G
K
G
L
K
V
G
D
V
V
I
G
T
E
T
A
H
H
D
V
D
V
T
A
F
G
Y
A
W
G
Q
V
P
Q
L
P
A
R
F
A
S
D
G
I
L
I
E
A
A
K
R
A
-
A
R
-
T
---
F
E
G
A
A
V
E
Q
G
L
I
V
S
G
D
R
F
V
H
S
S
E
G
V
A
E
I
R
K
H
F
P
E
V
K
A
V
E
M
E
A
A
A
I
A
Q
T
C
H
Q
L
E
T
P
F
V
I
I
R
A
V
S
D
S
A
D
E
K
A
D
I
S
F
D
E
F
L
K
T
A
A
A
N
S
A
K
M
V
A
E
I
V
K
S
L
-
106
HHSearch
72.73
34%
-20
- C1 -
-
4OY3
1
MQMTN_HELPJ
A:
[3-231]
Q
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
--
V
-
D
F
E
E
I
P
L
---
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
K
E
F
L
V
S
E
F
-
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
N
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
67
PsiBlast_CBE
69.97
35%
-12
- C1 -
-
4FFS
1
MQMTN_HELPJ
A:
[12-239]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
78
PsiBlast_CBE
69.73
35%
-13
- C1 -
-
4WKN
1
MQMTN_HELPJ
A:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
70
PsiBlast_CBE
69.63
35%
-10
- C1 -
-
4YO8
2
MQMTN_HELPJ
B:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
76
PsiBlast_CBE
69.50
35%
-10
- C1 -
-
4WKP
2
MQMTN_HELPJ
A:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
68
PsiBlast_CBE
69.27
35%
-13
- C1 -
-
5KB3
1
MQMTN_HELPJ
A:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
66
PsiBlast_CBE
69.27
35%
-12
- C1 -
-
4OJT
2
MQMTN_HELPJ
A:
[4-231]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
80
PsiBlast_CBE
68.98
35%
-13
- C1 -
-
4OY3
1
MQMTN_HELPJ
A:
[4-231]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
N
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
79
PsiBlast_CBE
68.81
35%
-13
- C1 -
-
4P54
1
MQMTN_HELPJ
A:
[4-231]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
N
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
77
PsiBlast_CBE
68.60
35%
-13
- C1 -
-
4WKO
1
MQMTN_HELPJ
A:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
75
PsiBlast_CBE
68.44
35%
-9
- C1 -
-
4WKP
2
MQMTN_HELPJ
B:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
IPL
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
72
PsiBlast_CBE
68.12
35%
-10
- C1 -
-
4YNB
4
MQMTN_HELPJ
A:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
73
PsiBlast_CBE
68.06
35%
-9
- C1 -
-
4WKP
2
MQMTN_HELPJ
D:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
IPL
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
74
PsiBlast_CBE
67.83
35%
-10
- C1 -
-
4WKP
2
MQMTN_HELPJ
C:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
IPL
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
71
PsiBlast_CBE
67.39
35%
-10
- C1 -
-
4YO8
2
MQMTN_HELPJ
A:
[18-245]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
59
PsiBlast_CBE
66.93
36%
13
- C1 -
-
3NM6
6
MQMTN_HELPJ
B:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
LFGV
D
F
E
--
E
I
P
L
--------
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
69
PsiBlast_CBE
66.82
35%
-9
- C1 -
-
5CCE
3
MQMTN_HELPJ
A:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
60
PsiBlast_CBE
66.46
36%
19
- C1 -
-
3NM5
2
MQMTN_HELPJ
B:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
LFGV
D
F
E
--
E
I
P
L
--------
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
85
PsiBlast_CBE
66.24
34%
-9
- C1 -
-
4BMZ
2
MQMTN_HELPY
A:
[24-251]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
I
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
E
S
L
N
A
L
A
K
E
V
-
A
N
-
E
---
Q
H
I
V
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
N
N
A
D
E
E
A
N
M
S
F
D
A
F
L
E
K
S
A
Q
T
S
A
K
F
L
K
S
M
V
D
E
L
-
84
PsiBlast_CBE
66.02
34%
-11
- C1 -
-
4BMZ
2
MQMTN_HELPY
B:
[24-251]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
I
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
E
S
L
N
A
L
A
K
E
V
-
A
N
-
E
---
Q
H
I
V
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
N
N
A
D
E
E
A
N
M
S
F
D
A
F
L
E
K
S
A
Q
T
S
A
K
F
L
K
S
M
V
D
E
L
-
82
PsiBlast_CBE
65.02
34%
-10
- C1 -
-
4BMX
2
MQMTN_HELPY
B:
[24-251]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
----
L
F
G
-----
V
D
-
F
E
E
I
P
L
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
I
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
E
S
L
N
A
L
A
K
E
V
-
A
N
-
E
---
Q
H
I
V
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
E
A
N
M
S
F
D
A
F
L
E
K
S
A
Q
T
S
A
K
F
L
K
S
M
V
D
E
L
-
61
PsiBlast_CBE
64.32
36%
18
- C1 -
-
3NM5
2
MQMTN_HELPJ
A:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
L
F
G
V
D
F
E
--
E
I
P
L
--------
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
63
PsiBlast_CBE
64.04
36%
14
- C1 -
-
3NM4
4
MQMTN_HELPJ
A:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
L
F
G
V
D
F
E
--
E
I
P
L
--------
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
A
D
E
K
A
G
M
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-
62
PsiBlast_CBE
63.28
36%
0
- C1 -
-
3NM4
4
MQMTN_HELPJ
B:
[3-230]
-
K
I
G
I
L
G
A
M
R
E
E
I
T
P
I
L
E
LFGV
D
F
E
--
E
I
P
L
--------
G
G
N
V
F
H
K
G
V
Y
H
N
K
E
I
I
V
A
Y
S
K
I
G
K
V
H
S
T
L
T
T
T
S
M
I
L
A
F
G
V
Q
K
V
L
F
S
G
V
A
G
S
L
V
K
D
L
K
I
N
D
L
L
V
A
T
Q
L
V
Q
H
D
V
D
L
S
A
F
D
H
P
L
G
F
I
P
E
S
A
I
F
I
E
T
S
G
S
L
N
A
L
A
K
K
I
-
A
N
-
E
---
Q
H
I
A
L
-
K
E
G
V
I
A
S
G
D
Q
F
V
H
S
K
E
R
-
K
E
F
L
V
S
E
F
K
A
S
A
V
E
M
E
G
A
S
V
A
F
V
C
Q
K
F
G
V
P
C
C
V
L
R
S
I
S
D
N
-------
S
F
D
E
F
L
E
K
S
A
H
T
S
A
K
F
L
K
S
M
V
D
E
L
-