@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y2H4: (2018-01-30 )
MMAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRLKQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQEKNELSRTERIKQIAEEKGLSINDDNLRKVK
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------.........10.-----.......20........30......--..40....------....50.......--.60........70....--....80........90......-..100.......110......--------.---120.......130..----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------M
M
A
E
L
K
K
M
QDYE-----Y
D
L
P
E
L
VDQ
P
E
Q
QMPDSSSN
Q
E
I
I
L--PQ
S
P
A
K
R
L
------
K
Q
I
S
A
L
E
K
I
A
V
A
S
--
V
A
I
A
I
V
A
L
C
V
L
T
V
M
L
RT--NISGA
E
K
E
I
T
S
I
Q
T
EIND
K
K
Q
E
-
K
T
S
L
E
Q
E
K
N
E
L
S
R
T
E
R
I
K
Q
I
A
--------
E
---EKGLSINDDNLRKVK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
60.53
26%
114
- C2 -
-
4KYI
5
?
A:
[4-544]
-----------------G
S
E
I
S
K
T
EAG
Q
Y
S
V
S
A
P
E
H
K
G
L
V
L
S
G
G
GAKGISY
L
G
M
I
Q
A
L
Q
E
R
GKIKNLT
H
V
S
G
A
S
A
G
A
M
T
A
S
I
L
A
V
GMD
I
K
D
I
K
K
L
I
E
G
LDITKLLDNSGVGFRARG
D
R
F
R
N
I
L
D
V
I
Y
M
M
Q
M
K
K
H
L
E
S
V
Q
-----
Q
P
I
P
-----
P
E
Q
Q
M
N
Y
G
I
L
K
Q
K
I
A
L
--
Y
E
D
K
L
S
R
------------------
A
G
--
I
V
I
N
N
V
D
D
I
I
N
L
T
K
S
V
K
--
D
L
E
K
L
D
K
A
L
N
S
I
P
T
E
L
K
G
A
K
G
E
-
Q
--
L
E
N
P
R
L
T
L
G
D
L
G
R
L
R
E
L
------------------
L
P
E
E
N
K
H
L
I
K
N
L
S
V
V
V
T
NQTKH
E
L
E
R
Y
S
EDTTPQQS
I
A
Q
V
V
Q
W
S
G
AHPVLFV
P
G
R
N
AKG
E
Y
I
A
D
GGI
L
D
N
M
P
E
I
E
GLDREE
V
L
C
V
K
A
E
A
G
T
A
F
E
D
R
V
N
K
A
K
Q
S
A
M
E
A
I
S
W
F
K
A
R
M
D
S
L
VTSSVLNREKV
Y
Y
N
I
D
N
M
I
Y
I
N
TGEVTTTNTSPT
P
E
Q
R
A
R
A
V
K
N
G
Y
D
Q
T
M
Q
L
L
D
S
H
KQTFDH
P
L
M
A
I
L
Y
I
GHDKLKDALIDEKSE
K
E
I
F
E
A
S
A
H
A
Q
A
I
L
H
L
Q
E
Q
I
V
K
E
M
N
D
GDYSS
V
Q
N
Y
L
D
Q
I
E
D
I
L
T
VDAKMD
D
I
Q
K
E
K
A
F
A
L
C
I
K
Q
V
N
F
L
S
E
G
K
L
E
T
Y
L
N
K
V
E
A
E
A
K
A
A
AEPSWA
T
K
I
L
N
L
L
W
AP
I
E
W
V
V
SLFKGPAQDFK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
57.10
19%
-161
- C3 -
-
3HE5
-
?
C:
[3-34]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
A
Q
L
E
N
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
-
N
L
H
K
K
D
L
I
A
Y
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
56.91
29%
-118
- C3 -
-
3AJB
-
PEX3_HUMAN
A:
[73-162]
--------------------------------------------------------------------------------------------------------------------------------------------------
L
P
T
L
R
E
A
L
M
Q
Q
L
--
N
S
E
S
L
T
A
L
L
--
K
N
R
P
S
N
K
L
------
E
I
W
E
D
L
K
I
I
S
F
T
R
--
S
T
V
A
V
Y
S
T
C
M
L
V
V
L
L
R
V
Q
L
N
I
I
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
Fugue
56.34
20%
67
- C1 -
-
5H9D
-
?
C:
[3-190]
----------------------------------------------------------------------------------------------------------------------TTVSKLERQ
I
E
E
R
L
K
G
V
S
E
Y
E
SININ
H
R
L
G
K
L
L
D
S
Y
D
--
I
P
D
V
A
K
V
A
C
L
T
I
--
D
T
S
-
M
R
H
L
------
D
D
I
T
Y
N
H
L
S
K
H
S
I
--
L
I
G
D
L
I
S
A
H
F
Y
T
L
L
A
E
I
--
N
D
L
S
F
Q
N
E
I
S
K
A
I
V
E
I
N
E
L
K
S
S
-
L
H
H
--
Q
A
L
N
D
Y
E
I
S
Q
A
I
V
K
I
E
TLFPYITL
S
---
H
F
G
I
N
I
D
E
S
E
I
Y
N
Y
L
FEDMSDYYPSYFKKYNQSEVKHYLHDIQKSYLKSRGN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
56.10
29%
-99
- C3 -
-
3MK4
-
PEX3_HUMAN
A:
[34-143]
--------------------------------------------------------------------------------------------------------------------------------------------------
L
P
T
L
R
E
A
L
M
Q
Q
L
--
N
S
E
S
L
T
A
L
L
--
K
N
R
P
S
N
K
L
------
E
I
W
E
D
L
K
I
I
S
F
T
R
--
S
T
V
A
V
Y
S
T
C
M
L
V
V
L
L
R
V
Q
L
N
I
I
G
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
55.11
29%
6
- C3 -
-
4ZRY
-
B:
[17-87]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
H
G
D
S
V
R
N
--
S
K
I
E
I
S
E
L
N
R
V
I
Q
R
L
R
S
--
E
I
D
N
V
K
K
Q
I
S
N
L
Q
Q
S
I
S
D
A
E
Q
R
G
E
N
A
L
K
D
A
K
N
K
L
N
D
L
E
D
A
L
Q
Q
A
--------
K
---
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
50.44
30%
-80
- C3 -
-
5U5A
-
?
A:
[2-29]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
A
L
K
-
E
N
A
A
L
K
E
E
-
I
A
A
L
K
K
E
I
A
A
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
50.01
29%
178
- C3 -
-
4RH7
-
DYHC2_HUMAN
A:
[2064-2150]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
V
L
L
K
T
--
K
Q
D
E
A
D
A
A
L
Q
M
I
T
V
S
M
Q
D
A
S
E
Q
-
K
T
E
L
E
R
L
K
H
R
I
A
--
E
E
V
V
K
I
E
--------
E
---
R
K
N
K
I
--
D
D
E
L
K
E
V
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
48.54
18%
36
- C2 -
-
4ZC4
-
LARP1_HUMAN
A:
[12-158]
-------------------------------------------------------------------------------------------------------------------------QH
P
S
H
E
L
L
K
E
N
G
F
T
Q
H
V
Y
-----
H
K
Y
R
R
R
C
L
N
E
R
K
R
L
G
I
G
Q
S
Q
E
M
N
T
L
--
F
R
F
W
S
F
F
L
R
D
HFN
K
K
M
Y
E
E
F
K
Q
L
A
L
E
D
--
A
K
E
G
Y
R
--
Y
G
L
E
C
L
F
R
Y
--
Y
S
Y
G
L
E
K
K
F
---
R
L
D
I
F
K
D
F
Q
E
-
E
T
V
K
D
Y
E
A
G
Q
L
Y
G
L
E
K
F
W
A
F
L
--------
K
Y
SK
A
K
N
L
D
I
-
D
P
K
L
Q
E
Y
L
G
K
F
R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
48.24
24%
49
- C3 -
-
3HE5
-
?
C:
[6-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
--
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
N
L
H
K
K
D
L
-
I
A
Y
L
E
K
E
I
A
N
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
46.98
15%
-
* C3 *
-
3W8V
3
?
C:
[3-28]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
L
E
K
K
V
S
A
L
E
K
K
-
V
A
G
L
E
K
E
V
A
R
L
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
46.21
47%
-124
- C3 -
-
3MBC
-
IDH_CORGL
A:
[91-111]
-------------------------------------------------------------------------------------------------------------------------------
L
K
A
A
I
K
E
L
Q
D
Q
G
-----
Y
D
I
P
E
L
P
D
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
HHSearch
46.02
22%
11
- C3 -
-
2G9J
-
TPM1_RAT
B:
[1-27]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
A
I
K
K
K
M
Q
M
L
K
L
D
-
N
Y
H
L
E
N
E
V
A
R
L
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
45.64
19%
42
- C3 -
-
4PKF
3
?
A:
[8-864]
K
V
L
E
Y
KG
K
K
L
N
FTPEDPAEETIPADELHEHLQKPST
A
R
T
K
R
L
K
E
R
CRWKHASAGEFIEKS
V
T
A
G
I
E
R
M
R
Y
L
T
E
A
H
K
A
S
EGKP
E
A
I
R
R
A
L
G
L
A
N
V
L
N
K
S
T
L
V
L
Q
E
DEFIVGYHAEDPN
M
F
P
L
Y
PELS
H
M
A
V
Q
D
Y
L
R
S
D
Y
S
-----
P
Q
P
A
D
E
A
A
A
I
N
E
Y
W
K
P
H
S
L
Q
S
K
C
Q
P
YF
D
P
A
D
L
G
R
M
------
Y
Q
V
S
S
M
E
A
P
S
F
A
S
G
Y
N
S
I
V
P
P
Y
E
T
V
L
E
D
G
L
L
A
--
R
I
K
L
A
E
K
H
I
A
E
A
Q
A
D
M
S
-------------
T
F
P
W
N
G
T
K
G
L
D
N
I
A
--------
K
---
I
D
N
W
K
A
M
V
I
A
C
K
A
V
I
S
W
A
R
R
Q
G
R
L
C
K
I
V
A
E
NFETD
P
K
R
Q
A
E
L
L
E
I
A
D
I
C
Q
R
IPAEPCKG
L
K
D
A
M
Q
A
K
F
F
T
F
L
I
C
H
AIE
R
Y
A
S
G
YAQK
E
D
T
L
L
W
P
Y
Y
K
A
S
VVDKKFQPMS
H
M
D
A
V
E
L
V
E
M
E
R
L
K
I
S
E
HGAGKS
R
A
Y
R
E
I
F
PGSN
D
L
F
I
L
T
V
G
GTNAKGEDACN
D
M
T
D
A
I
L
E
A
A
K
R
IRTAEP
S
I
V
F
RYSKKNR
E
K
T
L
R
W
V
F
E
C
I
R
D
GLGYP
S
I
K
H
D
E
I
G
T
E
Q
M
K
E
Y
A
K
F
SLNGNGAT
D
E
E
A
H
NWVNVLC
M
S
P
G
I
H
G
RRKTQKTRSE
G
G
G
S
I
F
P
A
K
L
L
E
I
S
L
N
D
GYDWSYADMQLGPKTGDLSSLKS
F
E
D
V
W
E
A
F
R
K
Q
Y
Q
Y
A
I
N
L
C
I
S
T
K
D
V
S
R
Y
F
E
Q
R
FLQM
P
F
V
S
A
I
D
D
G
C
M
E
L
GMDACALSE
Q
P
N
G
W
H
N
P
I
T
T
I
V
A
A
N
S
L
V
A
I
K
K
LVFEEKKYT
L
E
Q
L
S
Q
A
L
K
A
N
WEGF
E
E
M
R
V
D
F
K
R
APKWGNDD
D
Y
A
D
G
I
I
T
R
F
Y
E
EI
I
G
G
E
M
R
K
ITNYSG
G
P
V
M
P
TGQAVG
L
Y
M
E
V
G
S
R
TGPTPDGRFGGEAADDGGISPYMGTDKKG
P
T
A
V
L
R
S
V
S
K
VQKNQK
G
N
L
L
N
Q
R
L
S
V
P
I
M
R
SKH
G
F
E
I
W
N
S
Y
I
K
T
W
H
D
L
NID
H
V
Q
F
N
VVS
T
D
E
M
R
A
A
Q
R
EPEKHHD
L
I
V
R
V
S
GYSARFVDIP
T
Y
G
Q
N
T
I
I
A
RQE
Q
D
F
S
A
S
D
L
E
F
L
NVEI
14
HHSearch
44.50
11%
-
- C3 -
-
1KD8
1
?
E:
[1-28]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
K
Q
L
K
A
K
V
E
E
L
K
S
K
-
L
W
H
L
K
N
K
V
A
R
L
K
K
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
44.38
30%
-
- C3 -
-
5U59
-
?
A:
[2-29]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
I
A
A
L
K
-
E
N
A
A
L
K
E
E
-
I
A
A
L
K
K
E
I
A
A
L
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
44.08
24%
96
- C3 -
-
3HE5
-
?
E:
[6-42]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
E
N
--
E
V
A
S
L
E
N
E
N
E
T
L
K
K
K
N
L
H
K
K
D
L
-
I
A
Y
L
E
K
E
I
A
N
L
R
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
43.88
12%
-32
- C3 -
-
2YY0
-
MYCBP_HUMAN
D:
[60-92]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
--
E
I
E
L
L
R
L
E
L
A
E
M
K
E
K
Y
E
A
I
V
E
E
-
N
K
K
L
K
A
K
L
A
Q
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
42.23
28%
74
- C3 -
-
1A93
2
B:
[1-32]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
G
M
R
R
K
N
D
T
H
Q
Q
D
I
D
D
L
K
R
Q
-
N
A
L
L
E
Q
Q
V
R
A
L
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36
Fugue
41.30
28%
38
- C3 -
-
1L4A
-
CPLX_DORPE
E:
[49-76]
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E
-
R
R
K
E
K
H
R
K
M
E
E
E
R
E
E
M
R
Q
T
I
R
--------
D
---
K
Y
G
L
K
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