@TOME V2.3
(Mar 2018)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Q3Y3H9: (2018-02-05 )
MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVETAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHFFSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNYYVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE
Atome Classification :
(20 SA)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.....-----------....10...-.....20.......--.30----....-.....40........50........60........70........80........90....---------------....100-.---...-...110--........120......-..130--.-----.......140-...---------....150......-.160-........-170......-.180...-..-------..190....----------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(QMean)
(Ligand)
(Uniprot)
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MT
Q
E
I
-----------
K
K
L
P
V
I
F
L
G
-
L
F
F
I
T
VG
L
N
W
F
L
L
P
--
H
D
-----
I
A
S
A
-
G
V
G
A
I
G
H
L
V
E
T
A
F
S
IQR
S
V
T
V
W
S
I
N
L
M
M
L
L
L
A
A
V
L
LG
K
S
V
F
F
K
T
V
A
G
S
L
L
F
P
V
V
L
E
IVP
K
V
---------------
E
M
I
S
S
H
F
-
F
---
S
L
I
-
S
G
S
L
L
---
F
S
LGV
Y
T
L
Y
T
-VGASNG-
G
I
TI---
P
-----
P
I
I
F
H
K
F
FRL-PMP---------QG
L
L
L
T
N
S
L
I
V
F
L
-
N
Y
Y
--
V
F
G
L
L
E
T
L
-
F
V
L
L
S
I
T
V
S
-
S
L
F
M
K
I
L
-
I
R-------LSPVSRKFE----------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
74.86
23%
-74
- C2 -
-
5GGF
-
PMGT1_HUMAN
A:
[6-555]
RVLD
V
E
V
Y
S
S
RS
K
V
Y
V
A
V
DGTTVLEDEAREQGR
G
I
H
V
I
V
L
NQATGHVM
A
K
R
V
F
DTYSPH
E
D
E
A
M
V
L
F
L
N
M
VAPG
R
V
L
I
C
T
V
K
DEGSFHLK
D
T
A
K
A
L
L
R
S
L
GS
Q
A
G
P
A
LGWR
D
T
W
A
F
V
G
R
KGGPVF
G
E
K
H
S
K
S
PALSSWGD
P
V
L
L
K
T
D
V
P
L
S
S
A
E
E
A
E
CHWADT
E
L
N
R
R
R
R
R
F
C
S
K
VEGYGSVCSCKDPTPIEFS
P
D
P
L
P
DNKVLN
V
P
V
A
V
I
A
G
NR
P
N
Y
L
Y
R
M
L
R
S
L
L
S
A
Q
G
V
S
P
-----------
Q
M
I
T
V
F
I
D
G
----------
Y
Y
E
E
P
--
M
D
-----
V
V
A
L
F
G
L
R
G
I
Q
H
T
-----
P
I
S
I
K
N
A
R
V
S
Q
H
Y
K
A
S
L
T
A
T
F
N
L
-----
F
P
E
A
K
F
A
V
V
L
E
E
D
L
D
I
A
V
----------------------
D
F
-
F
---
S
F
L
-
S
Q
S
I
H
---
L
L
E
E
D
D
S
L
Y
C
-
I
S
A
W
N
D
Q
G
Y
E
H
---
T
-----
A
E
D
P
A
L
L
Y
R
V
E
T
M
P
G--------
L
G
W
V
L
R
R
S
L
Y
K
E
E
-
L
E
P
--
K
W
P
T
P
E
K
L
-
W
D
-----------
W
D
M
W
-
M
R
-------
M
P
E
Q
R
R
G
R
E
C
I
I
P
DVSRSYHFGIKHKFNTVPG
V
Q
L
R
NVDSLK
K
E
A
Y
E
V
E
V
H
R
L
L
S
E
A
E
V
L
DHSKNPCEDSFLPDTEG
H
T
Y
V
A
F
I
RMEKDDDF
T
T
W
T
Q
L
A
K
C
L
HIWDLDVRGNHRG
L
W
R
L
F
R
KK
N
H
F
L
V
V
G
V
PASPYSVKKPPSVT
P
I
F
L
E
P
23
Fugue
69.29
17%
-92
- C4 -
-
5IPX
-
?
A:
[32-322]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLF
N
H
L
F
R
Y
H
YPS
W
D
Q
I
L
Q
E
L
D
T
L
S
V
A
T
LNPD
C
H
V
P
A
L
N
V
E
-
K
T
L
Y
L
A
K
T
I
Q
I
L
V
Q
--
H
R
Q
S
EPY
L
V
P
A
-
A
R
A
N
L
A
Y
S
L
Q
Q
L
Y
K
L
G
N
D
K
I
R
G
V
I
N
G
M
L
P
L
V
D
A
G
C
I
G
F
E
R
E
L
I
K
G
L
P
R
V
L
T
L
Q
Y
P
H
T
A
P
C
T
---------------
E
W
C
L
S
H
F
-------
V
-
G
A
S
G
R
---
L
R
S
E
V
R
D
I
L
T
----
T
H
N
-
G
T
C
A
---
P
S
F
E
W
M
A
S
V
V
K
K
F
F
L
V
-
E
T
V
IYEDFQD--
T
D
F
N
V
Q
L
N
L
C
F
F
W
-
T
A
V
--
V
Q
M
Y
Q
R
C
I
-
Y
---
E
Q
K
L
V
-
H
I
I
S
T
S
L
-
T
L
-------
L
K
S
T
A
R
S
F
F
A
W
Y
D
L
Y
RPNLGS
A
A
L
V
K
Y
T
E
H
L
I
R
A
LTPDCS
D
V
E
L
G
E
L
C
S
H
L
H
H
C
K
H
A
L
F
S-------------------------------------------------------------------------------------------
29
Fugue
64.65
15%
-79
- C3 -
-
4OMH
1
COTB2_STRMJ
A:
[13-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IGRSSVRPY
L
E
E
C
T
R
R
F
Q
E
M
F
D
R
H
V
V
T
R
P
-----------
T
K
V
E
L
T
D
A
E
-
L
R
E
V
I
D
D
C
N
A
A
V
A
P
LG
K
T
-----
V
S
D
E
-
R
W
I
S
Y
V
G
V
V
L
W
S
Q
S
P
R
H
I
K
D
M
E
A
F
K
A
V
C
V
L
N
C
V
T
F
V
W
D
D
M
D
P
A
L
H
D
F
G
L
F
L
P
Q
L
R
K
I
C
E
K
Y
YG
P
E
D
A
E
V
A
Y
E
A
A
R
A
L
V
T
S
D
H
M
-
F
RDS
P
I
K
-
A
A
L
C
T
---
T
S
P
E
Q
Y
F
R
F
R
-
V
T
D
I
G
V
-
D
F
W
M
---
K
M
S
Y--
P
I
Y
R
H
P
E
F
T
E
-
H
A
K
T
S
L
A
A
R
M
T
T
R
G
L
T
I
V
N
D
F
Y
S
Y
D
-
R
E
V
--
S
L
G
Q
I
T
N
C
-
F
R
L
C
D
V
S
D
E
-
T
A
F
K
E
F
F
Q
A
R
-------
L
D
D
M
I
E
D
I
E
C
I
K
A
FD
Q
L
T
Q
D
V
F
L
D
L
I
Y
G
N
F
V
W
T
T
S
N-------------------------------------------------------------------------------------------------------------------
22
Fugue
62.28
20%
-56
- C4 -
-
3ZC4
-
CSA5A_SULSO
A:
[8-164]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P
V
A
E
T
I
-----------
S
K
R
F
W
T
L
I
K
M
L
R
F
Y
V
V
L
R
R
F
G
Y
I
D
--
P
L
-----
I
Y
S
I
-
D
P
K
Q
I
K
D
V
L
S
E
A
L
R
E
F
V
S
Y
T
S
S
S
S
S
R
S
I
V
I
Y
D
----
D
P
K
N
P
V
T
A
Q
A
P
C
L
-------
V
V
A
K
R
---------------
D
E
I
P
Q
N
F
-
P
---
S
I
Y
-
R
------------
Y
T
I
Y
K
-
I
D
K
S
S
E
-
Y
C
I
S
---
P
-----
L
V
V
N
D
K
Y
A
T
L
-
I
T
P
---------
N
-------------------
E
S
V
I
K
E
F
-
F
D
K
L
D
S
N
I
---
Q
Y
A
R
V
L
-
A
S
-------
L
A
V
G
G
E
-------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
61.91
28%
-142
- C4 -
-
1VK9
1
?
A:
[2-148]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
D
K
I
-----------
H
H
H
H
----------------------
H
H
-----
V
E
--------
K
N
L
L
R
S
A
L
K
I
F
E
K
K
-----
D
L
S
L
L
A
Y
S
----
G
R
S
I
F
E
S
K
D
S
G
---
L
K
P
V
V
E
L
F
K
R
------------------------
F
---
D
N
L
-
E
G
S
L
V
---
I
D
-------
K
M
V
G
K
A
A
A
-
S
F
L
L
K
M
K
P
-----
D
H
I
H
A
K
V
I
S
K
-
P
A
L
---------
K
-----------
L
M
N
E
Y
G
Q
S
F
S
Y
D
E
K
I
P
F
V
L
G
K
D
G
K
S
M
C
P
F
E
K
L
V
-
L
E
MDD
P
E
E
I
I
R
I
V
L
S
K
F
-----------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
49.23
33%
-165
- C4 -
-
3UON
-
ACM2_HUMAN (first)
A:
[27-85]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
A
G
S
L
S
L
V
T
I
I
G
N
I
L
V
M
V
S
I
K
V
N
R
H
L
---------------
Q
T
V
N
N
Y
F
L
F
---
S
L
A
-
C
A
D
L
I
I
G
V
F
S
M
N
L
Y
T
L
Y
T
-
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
49.01
33%
-175
- C4 -
-
4MQT
1
ACM2_HUMAN
A:
[44-126]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
A
G
S
L
S
L
V
T
I
I
G
N
I
L
V
M
V
S
I
K
V
N
R
H
L
---------------
Q
T
V
N
N
Y
F
L
F
---
S
L
A
-
C
A
D
L
I
I
G
V
F
S
M
N
L
Y
T
L
Y
T
-
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
48.90
33%
-177
- C4 -
-
4MQS
-
?
A:
[44-123]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
L
V
A
G
S
L
S
L
V
T
I
I
G
N
I
L
V
M
V
S
I
K
V
N
R
H
L
---------------
Q
T
V
N
N
Y
F
L
F
---
S
L
A
-
C
A
D
L
I
I
G
V
F
S
M
N
L
Y
T
L
Y
T
-
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
43.03
51%
-257
- C5 -
-
2RIM
-
RT109_YEAST
A:
[42-100]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
42.59
51%
-257
- C5 -
-
2ZFN
-
RT109_YEAST
A:
[66-122]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
42.11
51%
-239
- C5 -
-
3Q66
-
?
C:
[48-72]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
41.62
51%
-214
- C5 -
-
3Q33
-
?
A:
[44-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
40.87
46%
-173
- C5 -
-
3QM0
-
?
A:
[44-73]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
V
Y
V
T
-
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
39.81
51%
-197
- C5 -
-
3Q35
-
RT109_YEAST
A:
[44-78]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
39.62
46%
-179
* C5 *
-
3CZ7
-
RT109_YEAST
A:
[42-71]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
V
Y
V
T
-
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
34.50
29%
-560
- C4 -
-
3S8F
3
COXA_THET8
C:
[6-19]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
-
G
A
L
A
V
I
L
V
L
-
T
L
T
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
33.14
9%
-358
- C1 -
-
1RQT
-
RL7_ECOLI
B:
[22-32]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
-----
I
S
A
M
E
E
K
F
G
V
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
33.03
51%
-
- C5 -
-
3Q68
-
RT109_YEAST
C:
[42-69]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
P
K
S
---------------
T
I
K
T
Q
H
F
-
F
---
S
L
F
H
Q
G
K
V
F
---
F
S
L
E
V
Y
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
28.71
31%
-242
- C4 -
-
1PI7
-
VPU_HV1LW
A:
[7-25]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
V
A
L
V
V
A
I
I
I
A
I
V
V
W
S
I
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
Fugue
28.71
31%
-242
- C4 -
-
1PI8
-
VPU_HV1LW
A:
[7-25]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
V
A
L
V
V
A
I
I
I
A
I
V
V
W
S
I
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------