Binding Site Information :
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Information extracted from the bests complexes created by comparative docking.



Prediction Binding Site :


Binding Site Prediction
[Download fasta file] - [Download text file]

Binding Site Number :C4_S1
Best Complexes choosen after comparative docking [pKd > 3] : 3 (5 maxi)

Complexes [Theoretical pKd]FileVolume (A3)
(FPocket)
Hydrophobicity
Score(FPocket)
Contacts Ligand/Receptor [<4A] in Site C4_S1
Complex: NAP_B_21(1NYT) / Model_75(1NYT/B) = [11.7] Download1693.2427.18MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCNVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAKKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDLEGDFDIVINATSASLSGDALQLPEKLKFKYAYEMAYGKPSSFLDQAKQRNVPYAEGFGMLVGQAIEAFSIWNGVRPQLKDFL
Complex: NDP_B_6(3SEF) / Model_22(3SEF/B) = [8.2] Download2348.1524.35MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCNVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAKKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDLEGDFDIVINATSASLSGDALQLPEKLKFKYAYEMAYGKPSSFLDQAKQRNVPYAEGFGMLVGQAIEAFSIWNGVRPQLKDFL
Complex: ATR_A_5(2HK9) / Model_13(2HK9/A) = [7.2] Download1495.0619.04MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCNVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAKKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDLEGDFDIVINATSASLSGDALQLPEKLKFKYAYEMAYGKPSSFLDQAKQRNVPYAEGFGMLVGQAIEAFSIWNGVRPQLKDFL
Consensus
[pKd Mean = 9.03]
-1845
(s=364)
23
(s=3)
MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCNVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAKKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDLEGDFDIVINATSASLSGDALQLPEKLKFKYAYEMAYGKPSSFLDQAKQRNVPYAEGFGMLVGQAIEAFSIWNGVRPQLKDFL



Statistical distribution of contacts between receptors and ligands in all complexes :
(only contacts < 8A are taken into consideration)


Res_NameRes_NumRes_AtNb_ContactsNb_ComplexesNb[At_Ligand]
ASN10O131[O],
PRO11CD131[O],
PRO11CG131[O],
PRO11O131[O],
GLN14O131[O],
SER15CA131[O],
SER15CB131[O],
SER15OG131[O],
ARG16CB131[O],
ARG16CZ331[O], 1[C], 1[N],
ARG16CG131[O],
ARG16N131[O],
ARG16CD331[C], 1[N], 1[O],
ARG16NE331[C], 1[N], 1[O],
SER17OG131[O],
LEU20CD1131[O],
VAL61CG1131[O],
VAL61C231[C], 1[O],
VAL61O632[O], 3[C], 1[P],
THR62N231[C], 1[O],
THR62C2633[P], 10[C], 1[N], 12[O],
THR62CB1836[O], 1[P], 1[N], 10[C],
THR62CG2934[O], 5[C],
THR62OG127310[O], 2[P], 2[N], 13[C],
THR62O1232[P], 2[C], 8[O],
THR62CA1735[O], 1[P], 1[N], 10[C],
VAL63CB49318[C], 2[N], 6[P], 23[O],
VAL63CA34318[O], 1[N], 11[C], 4[P],
VAL63CG15236[P], 20[C], 2[N], 24[O],
VAL63CG25132[N], 21[C], 5[P], 23[O],
VAL63C2638[C], 4[P], 14[O],
VAL63O1532[P], 5[C], 8[O],
VAL63N36316[O], 4[P], 14[C], 2[N],
PRO64CG931[C], 2[P], 6[O],
PRO64CA19312[O], 3[C], 4[P],
PRO64CD735[O], 2[P],
PRO64N19312[O], 3[P], 4[C],
PRO64C1431[C], 3[P], 10[O],
PRO64CB1732[C], 3[P], 12[O],
PRO64O1231[C], 2[P], 9[O],
PHE65C634[O], 2[P],
PHE65CB232[O],
PHE65O232[O],
PHE65N1232[P], 10[O],
PHE65CA632[P], 4[O],
LYS66CD31316[O], 1[N], 10[C], 4[P],
LYS66CA937[O], 2[P],
LYS66CB1631[C], 4[P], 11[O],
LYS66C434[O],
LYS66NZ39319[C], 2[N], 3[P], 15[O],
LYS66CG20312[O], 4[C], 4[P],
LYS66O232[O],
LYS66CE35318[O], 13[C], 1[N], 3[P],
LYS66N1038[O], 2[P],
GLU67CD12310[O], 2[P],
GLU67CA131[O],
GLU67CB332[O], 1[P],
GLU67OE11233[P], 9[O],
GLU67N735[O], 2[P],
GLU67OE219314[O], 2[C], 3[P],
GLU67CG1133[P], 8[O],
ALA85CB535[O],
VAL86O131[O],
ASN87OD1232[C],
ASN87CB431[O], 3[C],
ASN87ND2631[O], 5[C],
ASN87CG232[C],
THR101C331[O], 2[C],
THR101O332[C], 1[O],
ASP102CG1737[O], 2[N], 7[C], 1[P],
ASP102CA736[C], 1[O],
ASP102OD21836[O], 1[P], 2[N], 9[C],
ASP102CB936[C], 1[N], 2[O],
ASP102N431[O], 3[C],
ASP102C635[C], 1[O],
ASP102O631[O], 5[C],
ASP102OD11738[C], 2[N], 7[O],
GLY103N232[C],
GLY105O131[O],
GLY105CA231[C], 1[O],
GLY105N131[O],
GLY105C332[C], 1[O],
LEU106CA431[O], 1[N], 2[C],
LEU106CD1531[O], 3[C], 1[N],
LEU106CB631[N], 4[C], 1[O],
LEU106N531[N], 3[C], 1[O],
LEU125O4236[N], 22[C], 14[O],
LEU125CB731[O], 3[N], 3[C],
LEU125C34318[C], 6[N], 10[O],
LEU125CA633[O], 3[N],
GLY126N4433[P], 21[C], 6[N], 14[O],
GLY126O3231[P], 14[C], 17[O],
GLY126C48321[O], 18[C], 6[N], 3[P],
GLY126CA58323[O], 4[P], 25[C], 6[N],
ALA127C59315[C], 9[P], 35[O],
ALA127N65331[O], 19[C], 6[N], 9[P],
ALA127O56332[O], 15[C], 9[P],
ALA127CB41323[O], 15[C], 3[P],
ALA127CA4937[P], 15[C], 27[O],
GLY128C5436[P], 17[C], 31[O],
GLY128CA64337[O], 9[P], 18[C],
GLY128O43326[O], 11[C], 6[P],
GLY128N68339[O], 9[P], 17[C], 3[N],
GLY129N53330[O], 6[P], 17[C],
GLY129O3136[P], 6[C], 19[O],
GLY129C43323[O], 13[C], 1[N], 6[P],
GLY129CA43323[O], 6[P], 14[C],
ALA130C42321[O], 6[P], 14[C], 1[N],
ALA130CA5232[N], 22[C], 6[P], 22[O],
ALA130O24314[O], 6[C], 1[N], 3[P],
ALA130CB6432[N], 26[C], 6[P], 30[O],
ALA130N59327[O], 6[P], 25[C], 1[N],
THR131CA30319[O], 4[P], 7[C],
THR131C732[P], 5[O],
THR131CB33319[O], 4[P], 10[C],
THR131OG15336[P], 19[C], 28[O],
THR131N4931[N], 18[C], 6[P], 24[O],
THR131O333[O],
THR131CG2836[O], 2[C],
ARG132CA333[O],
ARG132CD131[O],
ARG132CB535[O],
ARG132CG434[O],
ARG132N1233[P], 9[O],
ARG132NE333[O],
ARG132CZ131[O],
GLY133N333[O],
VAL134CG1434[C],
VAL134CG2131[O],
ALA149O2433[N], 10[C], 11[O],
ALA149C938[O], 1[N],
ASN150CA4637[N], 18[C], 3[P], 18[O],
ASN150CG56321[O], 7[N], 25[C], 3[P],
ASN150N2133[N], 3[C], 3[P], 12[O],
ASN150CB45318[O], 3[P], 6[N], 18[C],
ASN150ND253321[O], 23[C], 6[N], 3[P],
ASN150C42315[O], 3[P], 9[N], 15[C],
ASN150OD166321[O], 12[N], 30[C], 3[P],
ASN150O2333[N], 5[C], 3[P], 12[O],
ARG151CD60318[O], 24[C], 15[N], 3[P],
ARG151O2233[P], 3[C], 4[N], 12[O],
ARG151NE6533[P], 15[N], 29[C], 18[O],
ARG151CB63318[O], 27[C], 15[N], 3[P],
ARG151CZ66330[C], 15[N], 3[P], 18[O],
ARG151C44315[O], 17[C], 9[N], 3[P],
ARG151CG58316[O], 15[N], 24[C], 3[P],
ARG151N58327[C], 10[N], 3[P], 18[O],
ARG151CA54316[O], 3[P], 12[N], 23[C],
THR152CA2633[P], 6[C], 2[N], 15[O],
THR152CG219314[O], 2[C], 3[P],
THR152C21315[O], 3[P], 3[C],
THR152O24315[O], 6[C], 3[P],
THR152N42315[O], 9[N], 15[C], 3[P],
THR152OG138315[O], 3[P], 6[N], 14[C],
THR152CB29315[O], 3[P], 2[N], 9[C],
LEU153N1239[O], 3[P],
LEU153CA535[O],
LEU153C535[O],
ALA154N535[O],
ALA154C232[O],
ARG155N936[O], 3[P],
ARG155CB24315[O], 6[C], 3[P],
ARG155O636[O],
ARG155C937[O], 2[P],
ARG155CG26316[O], 7[C], 3[P],
ARG155CD39321[O], 13[C], 5[P],
ARG155CZ38312[C], 5[P], 21[O],
ARG155NE35310[C], 4[P], 21[O],
ARG155CA1239[O], 3[P],
ALA156CA232[O],
ALA156CB131[O],
ALA156N737[O],
LEU159CD1232[O],
LEU177CD1834[C], 4[N],
LEU177CG533[N], 2[C],
LEU177CB131[C],
LEU177CD2533[N], 2[C],
ASN189ND21437[C], 2[N], 5[O],
ASN189OD13638[O], 8[N], 20[C],
ASN189N131[O],
ASN189CB331[C], 2[O],
ASN189C1938[O], 10[C], 1[N],
ASN189CA331[C], 2[O],
ASN189O23313[C], 2[N], 8[O],
ASN189CG1637[C], 2[N], 7[O],
ALA190N35317[O], 1[P], 16[C], 1[N],
ALA190C7936[P], 8[N], 34[C], 31[O],
ALA190CB5333[P], 24[C], 1[N], 25[O],
ALA190CA54325[O], 1[N], 25[C], 3[P],
ALA190O8739[N], 36[C], 6[P], 36[O],
THR191OG170336[C], 15[N], 19[O],
THR191C99334[O], 43[C], 16[N], 6[P],
THR191CG283330[O], 15[N], 34[C], 4[P],
THR191CA99335[O], 15[N], 41[C], 8[P],
THR191CB93331[O], 38[C], 15[N], 9[P],
THR191N8736[P], 11[N], 40[C], 30[O],
THR191O88326[O], 6[P], 43[C], 13[N],
SER192CB102337[O], 6[P], 42[C], 17[N],
SER192O64315[O], 14[N], 35[C],
SER192OG103339[O], 8[P], 15[N], 41[C],
SER192N103337[O], 42[C], 17[N], 7[P],
SER192C81322[O], 4[P], 15[N], 40[C],
SER192CA9936[P], 17[N], 42[C], 34[O],
ALA193CA4936[O], 15[N], 28[C],
ALA193CB4536[O], 15[N], 24[C],
ALA193O32316[C], 14[N], 2[O],
ALA193N71315[N], 39[C], 17[O],
ALA193C42315[N], 21[C], 6[O],
SER194N33317[C], 12[N], 4[O],
SER194C631[N], 2[C], 3[O],
SER194CA932[N], 4[C], 3[O],
SER194CB633[C], 3[O],
SER194OG935[O], 4[C],
SER194O131[O],
LEU195CD22237[O], 13[C], 2[N],
LEU195CA532[C], 3[O],
LEU195N932[N], 4[C], 3[O],
LEU195CD13432[P], 18[C], 2[N], 12[O],
LEU195C131[O],
LEU195CB1835[O], 2[N], 11[C],
LEU195CG2639[O], 2[N], 15[C],
SER196CB934[N], 5[C],
SER196CA333[N],
SER196C232[N],
SER196OG1537[N], 8[C],
SER196O131[N],
SER196N531[O], 4[N],
GLY197C232[N],
GLY197N131[N],
ASP198CG1236[N], 6[C],
ASP198OD2934[C], 5[N],
ASP198CB1538[C], 7[N],
ASP198O1537[N], 8[C],
ASP198OD1935[C], 4[N],
ASP198C1638[C], 8[N],
ASP198N733[C], 4[N],
ASP198CA1135[C], 6[N],
ALA199N834[N], 4[C],
ALA199C934[C], 5[N],
ALA199CA834[N], 4[C],
ALA199O834[N], 4[C],
ALA199CB734[C], 3[N],
LEU200CB1337[C], 6[N],
LEU200N1537[C], 8[N],
LEU200CG1035[C], 4[N], 1[O],
LEU200CA1739[C], 8[N],
LEU200CD2935[C], 3[N], 1[O],
LEU200O1136[N], 5[C],
LEU200CD11834[O], 8[C], 5[N], 1[P],
LEU200C1538[C], 7[N],
GLN201O532[C], 3[N],
GLN201CD2034[O], 7[N], 9[C],
GLN201CG1932[O], 8[N], 9[C],
GLN201N1537[C], 8[N],
GLN201CA1437[N], 7[C],
GLN201CB1431[O], 7[C], 6[N],
GLN201NE21931[P], 6[N], 8[C], 4[O],
GLN201C833[N], 5[C],
GLN201OE11933[O], 10[C], 6[N],
LEU202C231[C], 1[N],
LEU202N733[N], 4[C],
LEU202CB533[N], 2[C],
LEU202CG532[C], 3[N],
LEU202CA533[N], 2[C],
LEU202O231[N], 1[C],
LEU202CD2432[C], 2[N],
LEU202CD1432[C], 2[N],
PRO203N532[C], 3[N],
PRO203C331[C], 2[N],
PRO203CG834[N], 4[C],
PRO203CA331[C], 2[N],
PRO203CD1035[C], 5[N],
PRO203O533[C], 2[N],
PRO203CB432[N], 2[C],
GLU204O432[C], 2[N],
GLU204C432[C], 2[N],
LYS205CB734[C], 3[N],
LYS205NZ1534[O], 1[P], 4[N], 6[C],
LYS205N532[C], 3[N],
LYS205CD1432[O], 7[C], 5[N],
LYS205CA734[C], 3[N],
LYS205CG935[C], 4[N],
LYS205CE1934[O], 1[P], 5[N], 9[C],
LYS205C432[C], 2[N],
LYS205O533[N], 2[C],
LEU206N231[N], 1[C],
TYR212CD1131[N],
TYR212CE2131[N],
TYR212CZ331[N], 1[C], 1[O],
TYR212CE1531[O], 1[N], 3[C],
GLU213OE21538[C], 2[N], 5[O],
GLU213CA431[N], 3[O],
GLU213CD934[C], 1[N], 4[O],
GLU213CG1034[O], 1[N], 5[C],
GLU213O1132[N], 5[C], 4[O],
GLU213C1338[C], 2[N], 3[O],
GLU213OE1232[O],
GLU213CB232[O],
MET214CA3239[O], 4[N], 19[C],
MET214C36310[O], 22[C], 4[N],
MET214O3634[N], 22[C], 10[O],
MET214SD40316[O], 3[N], 18[C], 3[P],
MET214CE30311[O], 2[N], 15[C], 2[P],
MET214N2637[O], 16[C], 3[N],
MET214CG32312[O], 3[N], 17[C],
MET214CB38312[O], 2[P], 20[C], 4[N],
ALA215CB3238[O], 20[C], 4[N],
ALA215O1834[N], 9[C], 5[O],
ALA215CA3439[O], 21[C], 4[N],
ALA215C26314[C], 4[N], 8[O],
ALA215N3534[N], 21[C], 10[O],
TYR216CE2731[O], 4[C], 2[N],
TYR216C632[O], 2[N], 2[C],
TYR216CD12034[O], 4[N], 12[C],
TYR216CE121313[C], 4[N], 4[O],
TYR216CA1033[O], 5[C], 2[N],
TYR216CB932[O], 5[C], 2[N],
TYR216CG1133[O], 6[C], 2[N],
TYR216CD2734[C], 2[N], 1[O],
TYR216O933[C], 2[N], 4[O],
TYR216N2134[N], 11[C], 6[O],
TYR216CZ1232[O], 3[N], 7[C],
GLY217CA131[N],
GLY217N131[N],
SER221OG131[O],
LEU223CD2332[N], 1[C],
LEU223CD1232[O],
GLU235CB131[N],
GLU235CA131[N],
GLU235C231[N], 1[C],
GLU235O231[C], 1[N],
GLY236O1432[O], 9[C], 3[N],
GLY236C1036[C], 3[N], 1[O],
GLY236CA1232[O], 7[C], 3[N],
GLY236N733[C], 2[N], 2[O],
PHE237CA531[O], 2[C], 2[N],
PHE237CD1131[N],
PHE237C431[O], 2[C], 1[N],
PHE237CB231[N], 1[C],
PHE237CG131[N],
PHE237N631[O], 2[N], 3[C],
PHE237O431[O], 1[N], 2[C],
GLY238N331[N], 1[C], 1[O],
GLY238O331[N], 1[C], 1[O],
GLY238CA331[N], 1[C], 1[O],
GLY238C331[N], 1[C], 1[O],
MET239C735[C], 1[N], 1[O],
MET239N631[O], 1[N], 4[C],
MET239CE1833[N], 11[C], 4[O],
MET239CG1031[O], 2[N], 7[C],
MET239O735[C], 1[N], 1[O],
MET239CB932[N], 6[C], 1[O],
MET239SD18311[C], 3[N], 4[O],
MET239CA735[C], 1[N], 1[O],
LEU240C634[C], 1[N], 1[O],
LEU240CA1036[C], 2[N], 2[O],
LEU240CB1333[N], 8[C], 2[O],
LEU240CG1032[O], 2[N], 6[C],
LEU240N832[N], 5[C], 1[O],
LEU240CD21132[O], 7[C], 2[N],
LEU240O533[C], 1[N], 1[O],
LEU240CD11532[O], 3[N], 10[C],
VAL241CA331[O], 1[N], 1[C],
VAL241C131[O],
VAL241N431[N], 2[C], 1[O],
GLY242N131[O],
GLY242CA131[O],
GLY242C131[O],
GLN243NE2331[O], 2[C],
GLN243CD634[C], 1[N], 1[O],
GLN243OE1731[N], 5[C], 1[O],
GLN243CA332[C], 1[O],
GLN243C131[O],
GLN243CB731[N], 5[C], 1[O],
GLN243CG831[O], 1[N], 6[C],
GLN243N431[O], 1[N], 2[C],
GLN243O131[O],
ALA244CA131[O],
ALA244CB131[O],
ALA244N131[O],
Total = 380



Download csv file of statistical distribution of contacts