Binding Site Information :
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Information extracted from the bests complexes created by comparative docking.



Prediction Binding Site :


Binding Site Prediction
[Download fasta file] - [Download text file]

Binding Site Number :C1_S1
Best Complexes choosen after comparative docking [pKd > 3] : 1 (5 maxi)

Complexes [Theoretical pKd]FileVolume (A3)
(FPocket)
Hydrophobicity
Score(FPocket)
Contacts Ligand/Receptor [<4A] in Site C1_S1
Complex: NACID_C_3(3BT7) / Model_11(3BT7/A) = [11.2] Download--MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI
Consensus
[pKd Mean = 11.20]
-0
(s=0)
0
(s=0)
MTSSYRQQLQAKIDRITTQFSEFTPPTLEVFESPEQHFRMRAEFRIWHTENDMFYAMFERNDDGKQKTVVRIDEFPIADKSINDLMPLLLAELKANSLLSQRLFEVDFLATLSGEMLVTLIYHRKLNQEWEQAAKALAEKLNIKIMGRSRGQKIVIGDDFVVEEFELLNRSFKYKQIESSFTQPNAQVCKKMLQWACDAAEGSKKHLLELYCGNGNFTLPLSLKFERVLATELAKSSVYAAQWNIEQNQIDNIQVARLSAEEFTQAYQGEREFRRLQEADIDIQSYDFGTVFVDPPRAGIDDETLKLLQGFERIIYISCNPDTLYENLKTLTQTHRVTKFALFDQFPYTHHVESGVLLEKI



Statistical distribution of contacts between receptors and ligands in all complexes :
(only contacts < 8A are taken into consideration)


Res_NameRes_NumRes_AtNb_ContactsNb_ComplexesNb[At_Ligand]
ARG39CZ3211[P], 3[N], 15[C], 13[O],
ARG39NE2619[O], 1[P], 3[N], 13[C],
ARG39CG1718[C], 2[N], 1[P], 6[O],
ARG39CB1114[O], 2[N], 5[C],
ARG39CD2018[O], 1[P], 2[N], 9[C],
ARG41CA412[C], 1[N], 1[O],
ARG41CB513[O], 2[C],
ARG41C1014[C], 2[N], 4[O],
ARG41CZ2511[N], 2[P], 11[C], 11[O],
ARG41CD1116[O], 2[P], 3[C],
ARG41N211[O], 1[C],
ARG41NE1519[O], 4[C], 2[P],
ARG41CG914[O], 4[C], 1[P],
ARG41O1416[O], 1[P], 2[N], 5[C],
ALA42O1011[O], 4[N], 5[C],
ALA42CB1217[C], 3[N], 2[O],
ALA42C1713[O], 8[C], 6[N],
ALA42N914[C], 3[N], 2[O],
ALA42CA1317[C], 4[N], 2[O],
GLU43O2914[O], 10[N], 15[C],
GLU43CG28112[N], 12[C], 4[O],
GLU43OE148124[C], 18[N], 6[O],
GLU43OE240119[C], 2[P], 13[N], 6[O],
GLU43CD3816[O], 14[N], 18[C],
GLU43CA24113[C], 8[N], 3[O],
GLU43CB30116[C], 12[N], 2[O],
GLU43N2217[N], 12[C], 3[O],
GLU43C2614[O], 9[N], 13[C],
PHE44C1114[C], 5[N], 2[O],
PHE44CB1115[N], 4[C], 2[O],
PHE44O715[N], 2[C],
PHE44CD11315[C], 5[N], 3[O],
PHE44CE2712[N], 3[C], 2[O],
PHE44CE11313[O], 6[C], 4[N],
PHE44CZ813[N], 3[C], 2[O],
PHE44CG1114[N], 5[C], 2[O],
PHE44CA1618[C], 6[N], 2[O],
PHE44CD2613[N], 2[C], 1[O],
PHE44N1816[N], 9[C], 3[O],
ARG45CZ28113[C], 7[N], 8[O],
ARG45O212[N],
ARG45CA911[O], 4[C], 4[N],
ARG45N1714[O], 6[N], 7[C],
ARG45CG1013[N], 4[C], 3[O],
ARG45CB1515[N], 6[C], 4[O],
ARG45C313[N],
ARG45NE2015[O], 10[C], 5[N],
ARG45CD23110[C], 7[N], 6[O],
ALA56O1417[C], 5[N], 2[O],
ALA56N111[N],
ALA56CB211[N], 1[O],
ALA56C611[O], 2[C], 3[N],
ALA56CA311[N], 1[C], 1[O],
MET57CA1818[C], 5[N], 5[O],
MET57C1714[O], 3[N], 10[C],
MET57SD1313[N], 6[C], 4[O],
MET57CG1314[O], 3[N], 6[C],
MET57CE18110[C], 3[N], 5[O],
MET57CB2114[N], 11[C], 6[O],
MET57N912[O], 4[C], 3[N],
MET57O913[O], 4[C], 2[N],
PHE58C2217[O], 12[C], 1[P], 2[N],
PHE58CG32110[O], 5[N], 2[P], 15[C],
PHE58CE237110[O], 18[C], 1[P], 8[N],
PHE58CZ28113[C], 1[P], 5[N], 9[O],
PHE58O2719[O], 14[C], 1[P], 3[N],
PHE58CD12218[O], 10[C], 1[P], 3[N],
PHE58CB34116[C], 2[P], 5[N], 11[O],
PHE58N26115[C], 4[N], 7[O],
PHE58CE11615[O], 3[N], 8[C],
PHE58CD239111[O], 8[N], 2[P], 18[C],
PHE58CA2517[O], 4[N], 1[P], 13[C],
GLU59O1718[C], 1[P], 1[N], 7[O],
GLU59N1415[O], 7[C], 2[N],
GLU59CB412[C], 2[O],
GLU59CA1114[O], 1[N], 6[C],
GLU59CG111[O],
GLU59C1717[O], 8[C], 1[P], 1[N],
ARG60O1416[O], 1[P], 7[C],
ARG60CD1619[O], 5[C], 2[P],
ARG60CZ212[C],
ARG60CA1919[O], 8[C], 1[P], 1[N],
ARG60CB1816[C], 1[N], 2[P], 9[O],
ARG60CG1819[O], 6[C], 1[N], 2[P],
ARG60C1316[O], 1[P], 6[C],
ARG60N1818[C], 1[P], 1[N], 8[O],
ARG60NE813[C], 5[O],
ASN61O111[O],
ASN61C212[O],
ASN61CA313[O],
ASN61N713[C], 1[P], 3[O],
ASP62N111[O],
ASP62C111[O],
ASP63CG815[O], 2[C], 1[P],
ASP63N513[O], 2[C],
ASP63CA1016[O], 1[P], 3[C],
ASP63C513[C], 2[O],
ASP63OD11712[P], 5[C], 10[O],
ASP63O714[O], 3[C],
ASP63CB715[O], 2[C],
ASP63OD2312[O], 1[C],
THR68N111[O],
THR68O311[C], 2[O],
THR68C111[O],
VAL70CB111[O],
VAL70O111[O],
VAL70N111[O],
VAL70CG2111[O],
ILE72CG1111[O],
PHE75CB111[O],
PHE75CZ2216[O], 5[N], 11[C],
PHE75CE218110[C], 4[N], 4[O],
PHE75CD1512[C], 1[N], 2[O],
PHE75CG511[N], 2[C], 2[O],
PHE75CE11819[C], 5[N], 4[O],
PHE75CD2812[N], 4[C], 2[O],
ILE77CG2914[C], 2[N], 3[O],
ILE77C111[O],
ILE77CB512[C], 2[N], 1[O],
ILE77CD1813[C], 2[N], 3[O],
ILE77CG1312[C], 1[O],
ILE77CA111[O],
ALA78N111[O],
ALA78CB211[O], 1[N],
ARG102O311[C], 2[O],
ARG102CZ111[O],
ARG102NE111[O],
PHE104N111[O],
PHE104CG2119[C], 1[P], 3[N], 8[O],
PHE104CA212[O],
PHE104CB1215[O], 2[N], 5[C],
PHE104CE228111[O], 13[C], 1[P], 3[N],
PHE104CE146123[C], 1[P], 8[N], 14[O],
PHE104C313[O],
PHE104CZ40118[C], 2[P], 6[N], 14[O],
PHE104CD224110[O], 11[C], 1[P], 2[N],
PHE104O312[O], 1[N],
PHE104CD134110[O], 6[N], 1[P], 17[C],
GLU105CD4317[O], 23[C], 13[N],
GLU105N411[N], 3[O],
GLU105O111[O],
GLU105CG22110[C], 7[N], 5[O],
GLU105CA311[C], 1[N], 1[O],
GLU105OE256130[C], 17[N], 9[O],
GLU105CB1312[O], 6[N], 5[C],
GLU105C211[N], 1[O],
GLU105OE14719[O], 24[C], 14[N],
VAL106N111[N],
VAL106CA111[N],
VAL106C111[N],
VAL106O513[N], 1[C], 1[O],
ASP107OD21919[C], 7[N], 3[O],
ASP107CB311[C], 2[N],
ASP107CA211[N], 1[O],
ASP107CG1512[O], 6[C], 7[N],
ASP107N111[N],
ASP107OD11515[C], 7[N], 3[O],
PHE108O111[O],
PHE108N111[O],
THR119OG1111[O],
THR119CG2512[O], 3[C],
THR119CB111[O],
LEU120C312[O], 1[C],
LEU120O312[O], 1[C],
ILE121O713[C], 4[O],
ILE121CB1717[C], 1[N], 1[P], 8[O],
ILE121CA1315[C], 1[N], 7[O],
ILE121CG12011[N], 1[P], 10[C], 8[O],
ILE121CG229112[C], 2[N], 2[P], 13[O],
ILE121N614[C], 2[O],
ILE121C1411[P], 5[C], 8[O],
ILE121CD130115[C], 1[P], 6[N], 8[O],
TYR122O2412[P], 1[N], 10[C], 11[O],
TYR122CA1217[O], 4[C], 1[P],
TYR122CB611[P], 2[C], 3[O],
TYR122C1719[O], 1[P], 7[C],
TYR122N1411[P], 5[C], 8[O],
TYR122CG111[C],
HIS123NE231115[C], 1[P], 4[N], 11[O],
HIS123O312[O], 1[P],
HIS123CB1617[C], 1[P], 1[N], 7[O],
HIS123N1216[O], 5[C], 1[P],
HIS123CA1518[O], 6[C], 1[P],
HIS123CD230112[O], 4[N], 1[P], 13[C],
HIS123CE12712[N], 1[P], 13[C], 11[O],
HIS123ND12012[N], 1[P], 8[C], 9[O],
HIS123C711[P], 1[C], 5[O],
HIS123CG2112[N], 1[P], 9[C], 9[O],
ARG124CA111[O],
ARG124C111[O],
ARG124CB111[O],
ARG124N614[O], 1[P], 1[C],
ARG124O211[O], 1[C],
LYS125CD111[O],
LYS125N111[O],
LYS125NZ916[O], 1[C], 2[P],
LYS125CE111[O],
MET146CG111[O],
MET146SD311[O], 2[C],
GLY147C111[O],
GLY147O212[O],
ARG148O1416[C], 2[P], 6[O],
ARG148NE2312[N], 2[P], 11[C], 8[O],
ARG148CG1819[C], 1[P], 1[N], 7[O],
ARG148CA1417[C], 1[P], 6[O],
ARG148CZ2812[N], 2[P], 12[C], 12[O],
ARG148C1618[O], 6[C], 2[P],
ARG148CD24112[C], 1[P], 2[N], 9[O],
ARG148CB1818[O], 8[C], 1[P], 1[N],
ARG148N915[C], 4[O],
SER149C2017[C], 2[P], 11[O],
SER149N1718[O], 7[C], 2[P],
SER149CA1912[P], 6[C], 11[O],
SER149CB1519[O], 2[P], 4[C],
SER149OG913[C], 2[P], 4[O],
SER149O2312[P], 8[C], 13[O],
ARG150CA2212[P], 8[C], 12[O],
ARG150NE19111[O], 2[P], 6[C],
ARG150CZ26114[O], 3[P], 9[C],
ARG150CG1615[C], 2[P], 9[O],
ARG150CD1515[C], 2[P], 8[O],
ARG150N21111[O], 2[P], 8[C],
ARG150C1615[C], 2[P], 9[O],
ARG150CB19110[O], 2[P], 7[C],
ARG150O1312[P], 4[C], 7[O],
GLY151C715[O], 1[C], 1[P],
GLY151N2117[C], 3[P], 11[O],
GLY151CA1317[O], 4[C], 2[P],
GLY151O413[O], 1[P],
GLN152CB412[O], 1[C], 1[P],
GLN152C913[C], 1[P], 5[O],
GLN152O1517[C], 1[P], 7[O],
GLN152CG311[P], 2[O],
GLN152CD111[O],
GLN152N1317[O], 5[C], 1[P],
GLN152CA611[C], 1[P], 4[O],
LYS153CB811[P], 2[C], 5[O],
LYS153N411[C], 1[P], 2[O],
LYS153CE312[O], 1[C],
LYS153NZ411[C], 3[O],
LYS153CD713[C], 1[P], 3[O],
LYS153CG614[O], 2[C],
LYS153CA211[C], 1[O],
GLU178C111[O],
GLU178CD413[O], 1[C],
GLU178OE2613[O], 3[C],
GLU178OE1915[C], 4[O],
GLU178O111[O],
SER179OG2514[N], 1[P], 12[C], 8[O],
SER179CA1511[P], 3[N], 4[C], 7[O],
SER179C1016[O], 3[C], 1[P],
SER179CB2117[O], 9[C], 1[P], 4[N],
SER179O2519[O], 12[C], 1[P], 3[N],
SER179N212[O],
SER180O514[O], 1[P],
SER180OG111[O],
SER180N411[P], 3[O],
SER180CB111[O],
SER180CA411[P], 3[O],
SER180C511[P], 4[O],
PHE181CZ2412[N], 2[P], 10[C], 10[O],
PHE181CE21912[N], 1[P], 10[C], 6[O],
PHE181C811[P], 1[C], 6[O],
PHE181N814[O], 3[C], 1[P],
PHE181CG2312[N], 1[P], 13[C], 7[O],
PHE181CA1114[C], 1[P], 6[O],
PHE181CD22017[O], 2[N], 1[P], 10[C],
PHE181CE128113[C], 2[P], 2[N], 11[O],
PHE181O413[O], 1[P],
PHE181CB2217[O], 12[C], 1[P], 2[N],
PHE181CD13112[N], 2[P], 14[C], 13[O],
THR182CA915[O], 2[C], 1[P], 1[N],
THR182CB111[O],
THR182C1717[O], 2[N], 1[P], 7[C],
THR182O23110[O], 2[N], 2[P], 9[C],
THR182OG1211[O], 1[P],
THR182CG2111[O],
THR182N1113[C], 1[P], 1[N], 6[O],
GLN183O311[O], 1[N], 1[C],
GLN183OE118110[C], 2[N], 6[O],
GLN183CA17110[C], 2[N], 5[O],
GLN183C1014[O], 2[N], 4[C],
GLN183NE21212[N], 7[C], 3[O],
GLN183CG915[C], 2[N], 2[O],
GLN183CD1318[C], 2[N], 3[O],
GLN183CB812[O], 4[C], 2[N],
GLN183N1315[O], 6[C], 2[N],
PRO184CG28110[O], 3[N], 2[P], 13[C],
PRO184N1717[C], 1[P], 2[N], 7[O],
PRO184CA913[C], 1[P], 1[N], 4[O],
PRO184CD25110[C], 2[P], 2[N], 11[O],
PRO184C212[O],
PRO184CB2519[O], 12[C], 1[P], 3[N],
PRO184O111[O],
ASN185N312[O], 1[N],
MET192CG111[O],
MET192CE612[O], 1[N], 3[C],
MET192SD513[C], 1[N], 1[O],
TYR211O111[C],
ASN216OD1111[O],
PHE217CE2411[O], 2[C], 1[N],
PHE217CE1111[O],
PHE217CZ211[O], 1[C],
PHE217CD2111[O],
LEU233CD1411[C], 3[O],
LEU233O211[O], 1[C],
LEU233C111[C],
LEU233CB412[O], 2[C],
ALA234N211[C], 1[O],
ALA234C111[O],
ALA234CA513[O], 2[C],
ALA234CB713[O], 4[C],
LYS235NZ111[O],
LYS235N311[C], 2[O],
LYS235CE111[O],
LYS235CD111[O],
LYS235CG111[O],
LYS235CB111[O],
PHE292CE2111[O],
PHE292CZ111[O],
VAL293O211[C], 1[O],
VAL293C211[C], 1[O],
ASP294OD11012[O], 2[N], 6[C],
ASP294CG912[O], 2[N], 5[C],
ASP294O811[O], 5[C], 2[N],
ASP294CB611[O], 1[N], 4[C],
ASP294OD21012[O], 2[N], 6[C],
ASP294N411[O], 3[C],
ASP294CA611[O], 1[N], 4[C],
ASP294C811[O], 2[N], 5[C],
PRO295CB511[O], 4[C],
PRO295N711[O], 2[N], 4[C],
PRO295CD511[O], 4[C],
PRO295O1412[N], 7[C], 5[O],
PRO295CG514[C], 1[O],
PRO295CA711[O], 2[N], 4[C],
PRO295C1112[N], 6[C], 3[O],
PRO296CA26111[O], 1[P], 2[N], 12[C],
PRO296N1518[C], 2[N], 1[P], 4[O],
PRO296CD1311[P], 1[N], 6[C], 5[O],
PRO296CG2118[O], 1[P], 1[N], 11[C],
PRO296C2119[C], 2[N], 1[P], 9[O],
PRO296O1515[O], 1[P], 2[N], 7[C],
PRO296CB3112[P], 2[N], 16[C], 11[O],
ARG297CB2017[O], 11[C], 1[N], 1[P],
ARG297CG29111[O], 2[P], 2[N], 14[C],
ARG297CD32114[O], 14[C], 1[N], 3[P],
ARG297N26113[C], 2[N], 1[P], 10[O],
ARG297CZ44118[C], 2[N], 3[P], 21[O],
ARG297C1115[C], 1[P], 1[N], 4[O],
ARG297CA1911[P], 2[N], 10[C], 6[O],
ARG297O611[N], 3[C], 2[O],
ARG297NE40115[C], 2[N], 4[P], 19[O],
ALA298CB811[P], 3[C], 4[O],
ALA298CA513[O], 1[C], 1[P],
ALA298C111[O],
ALA298N1316[C], 1[N], 1[P], 5[O],
GLY299N211[O], 1[C],
ILE317N111[O],
ILE317CB511[O], 1[N], 3[C],
ILE317CG1211[C], 1[O],
ILE317CG2711[O], 1[N], 5[C],
ILE317O611[O], 1[N], 4[C],
ILE317C611[O], 4[C], 1[N],
ILE317CA411[O], 3[C],
ILE317CD1211[C], 1[O],
SER318N614[C], 1[N], 1[O],
SER318CB511[O], 4[C],
SER318O1012[N], 6[C], 2[O],
SER318CA812[N], 5[C], 1[O],
SER318C1213[O], 7[C], 2[N],
SER318OG514[C], 1[O],
CYS319SG2017[O], 10[C], 1[P], 2[N],
CYS319CA1612[N], 9[C], 5[O],
CYS319CB19110[C], 2[N], 7[O],
CYS319C1414[O], 8[C], 2[N],
CYS319N1312[N], 7[C], 4[O],
CYS319O17110[C], 2[N], 5[O],
ASN320CG111[O],
ASN320CA715[C], 1[N], 1[O],
ASN320N1112[O], 2[N], 7[C],
ASN320ND2111[O],
ASN320CB614[C], 1[N], 1[O],
GLN345C412[O], 2[C],
GLN345CB713[O], 1[N], 3[C],
GLN345CA111[O],
GLN345CD1616[O], 7[C], 1[P], 2[N],
GLN345O513[O], 2[C],
GLN345CG1412[N], 1[P], 6[C], 5[O],
GLN345OE1912[N], 4[C], 3[O],
GLN345NE21719[C], 2[N], 6[O],
PHE346C513[C], 2[O],
PHE346O815[C], 3[O],
PHE346CD22117[O], 2[N], 1[P], 11[C],
PHE346CE13213[N], 1[P], 15[C], 13[O],
PHE346CB1617[O], 1[P], 1[N], 7[C],
PHE346CZ28114[C], 1[P], 2[N], 11[O],
PHE346N412[C], 2[O],
PHE346CA1015[O], 5[C],
PHE346CE224111[C], 1[P], 2[N], 10[O],
PHE346CD129111[O], 13[C], 2[P], 3[N],
PHE346CG2419[O], 11[C], 1[P], 3[N],
PRO347C111[O],
PRO347O512[O], 3[C],
PRO347N111[O],
TYR348O111[O],
TYR348C111[O],
THR349CG21818[C], 1[P], 1[N], 8[O],
THR349O111[O],
THR349OG11317[O], 1[P], 5[C],
THR349C312[O], 1[C],
THR349CB1618[O], 1[N], 1[P], 6[C],
THR349N412[C], 2[O],
THR349CA814[C], 4[O],
HIS350CB111[O],
HIS350N413[O], 1[C],
HIS350C212[O],
HIS350CA111[O],
HIS351NE226113[O], 2[P], 1[N], 10[C],
HIS351C111[C],
HIS351CE12412[P], 11[C], 11[O],
HIS351CA713[O], 3[C], 1[P],
HIS351ND123110[O], 10[C], 2[P], 1[N],
HIS351CD22312[P], 1[N], 9[C], 11[O],
HIS351N713[O], 1[P], 3[C],
HIS351CG2119[C], 2[P], 10[O],
HIS351CB1812[P], 7[C], 9[O],
VAL352N111[O],
VAL352O611[O], 3[C], 2[N],
GLU353OE21112[O], 2[N], 7[C],
GLU353CD912[N], 5[C], 2[O],
GLU353N111[N],
GLU353OE1612[O], 3[C], 1[N],
GLU353CA511[O], 1[N], 3[C],
GLU353C111[O],
GLU353CB812[O], 4[C], 2[N],
GLU353CG912[O], 2[N], 5[C],
SER354N211[O], 1[C],
SER354O211[C], 1[O],
Total = 439



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