Modeling by threading (Tito software)
Unconserved sides chains calculation (Scwrl software)
Evaluation (QMean software)



Input alignment information:
Query sequenceMSDFSSSSSDSSSDDGIFTRRVEFQQRQRGASSSSSVPALGSSATRDVVAIISESAPPCTVDAVEAPATAGATTSRARSQPPDVAPVVLSERVTTQTSLQSASTGSEDKSSPGGSPVQRRRRRVAGTRPPAIKGALGSPTEPKQQRGRRSSVSDPGSPLELPPPSRSSSRQRRTSVHSMSTADLAAATLVRASSNTLSTSTNKRTGGRGGGGVRRRYPRGAATTSLRALSPVSVSPTASAVNARLLSDEAYLDMFHIPALIAQLSLSLMAAKPIDPRAFTRDWLADRLVSEEDEDDDNADDGGGSTNSGSGAREQGSQVPPSDTAVLTRSTELPSSTSFVFQASGSTMGDFASDSGAARPCLTEVSYRQGRSGQHSRQRRRTNTSGEDEADDVAKTPLEADSDGDKTGTVIDRPASVGHASRKRRAFERRAQRKDRQSVATPSESRQRGVCGISNGAESRRNEMSASSRNNTSDDAYSRSPRCGSLLTTLAPPPAEACEHREPRAAECEASSPMQRSEEAERNATAAAPSSLPPTPKTSSSSSPSSSSSSFTAFRSPGSDGVEWARVELQSRRTTVAGSSASADVDIPSSHRRMTMESESSTSTEGLSAPHGTTHGEHEVRQSSSSSRAAETAVNDVPALVTVERKGIHKSCSSSSSSSAGDGAHGLAALAHDRVGHTSGRAIELSTAASSMIRPEASVAKRGAAKEEFSRSDNEAEEGGEAERHSNYVAADIAEPAHSTTRGSEKDAADAAAAAAESHGRDGDDDFSFAMFVPILAVDATTNEVIDYREAGVSPPSAPAFSPTSGGACALPSYPTVSASGVGGGHLAQTHTSTAVTQSSGFPPYATRPVSSTFNVLPTPMLADLVGGGGLTNTSFGRRGVPNTSFGRRPAPMAGAAGRYVDPAAGAMTGSSSPPAPFITPHAPMDLPALGVSDGVVDGESLENLQLLGFPKLNSNLAAVSVGSVTGVRTSGSVVVAGEAASVRERKAVQDDDVADSNRAAPSAFCQSAVLHGATDGARNTNLSLTKDTLGPVVALSTASSPVSSTMKLESARRLGKLLDQLPAAKYAAAIVFLEGLLSSSGGSSDAAATPESESISMMTNIGDASNRNRGLLNLTSTAADTTLGSVGLSGDGSSPLVGSITPGRPWSGTFGPGRSPTGRARSFAHLVAGGSSQAPALAASGRNEDGAGALAMVSRAPEGGHSRSRSKGGSTSVEALVRDALSQSVLRSLPPTHEEVPGSVPSLPLRLEVSGRGAGEGTSMGMHRVPSPTRLENTHGERFASTATSTARANTSRGSSPVPVVPGGGSDDVTLQHPPSQSERSNLSFYKQPSSTDMSNLRRRSSSPSPGGYALTAAALQQQQQSQQQPVTRKATEDRLGSAVATMLPQSLSGPPPLSPAGNSSLATTGISVSEQKLMGVAVPTQPGASCVADHDEATTPEHSTARTATAADARGADSGNEDHQGAAFGGSDSCDLGSYAAQQRQNQALQHHHGIVSSSDQSLAAHATDQNTVDRFATTGAAAEAAEPSATVAPKALEGTQRRCSNGNGGSLLLLEQRGARGDGDESTLPPECGTHEQFMPLDAAANPISLHTHSAESVSSLSSGTAPITNSGADGGGGRRAGNAPGYWPGTFGNSQVSGSAAAEAPQERPQSGRELCSSAAKSSSASAGGSSGVVGWGGTVSDSPSPPLHAHHPHSAGRELEFEDVNLGATLRMAVALAAAAGTQSARTVYGSHSSSKDSMNGPAIKSSTPNQSAGVAVVSGANVVTADPFASADANEGLSSLATADETYVNDLFVTHSSQSPPTLHGNNHKPLLRMVDGSGAGEDCVSLPSSQTVSLLNTCSSSVAEGGDVSAATASILPPAIPPVAVSADGTVLATPITAAMTPIILEPSTQSPPRSELPMVTSSVVVAMNSFFSREDHVAPEELEVVREVVAHYDAFASLDETQLETLVRTMGRMELQRGATVVREGDSTLGQLLLIVSGKLTISRKGLVTRTLARGQFYGEMEMSYHVERSRVTLTAATPTVVLYALKKVDYQKLVIHEKDARRYMFLQYVNECVLFKGLSPYIKMRLADSFRVCRLRKGTKLTEQGASVEWMYLLMSGNVRMTYQAPPSTGGETSDWPLPWRGAAPEEEARHTVTTSHSFSNFAGSTTLSEAHMSSAASAAAASTAAGTSTTRCGTAPSGITGSLSSSLTPLTVASQLPSSALLLSQAAMASLNAGAQQQDMLAERAASSAEACKESPLISMVSPSPGANAATSRMPQLLHLPNAKAAHANSRGKSGDHLAEQGADDGPPRPNSSRPRSRRLQSQQDRSVSGWQGLSQPSASAAESLDTDNTKPPSPLSTSASVRQSANTLLDTTPHSNAASTVTTSLTNTAAALAGAAGVHKTVVVVDRSKGQLVGETEFVFKCKGLFTAVATTPVQAARISRLHFEAIMTRAVVEEMKRSMLLNPDYYFFEFTVPEALKEDMRRMLFRLNVGPAARRRTRHAQQHQRLRHSVTGVEGTVSGSRSRGGTAGGNRDSEAGRRHCRQSMVLSRRTQREHNRASFMDNITGGPGGSSNGPNGTTGSSGSNSHSTSPPLVAVCVQDGGRERNDGSTSQVGSKRHHAGHRRFRTAPLEISPTMARLSTERATADSVDAAGMESSALHYLAAPTVCGGPFASPAVASTAVVSSTSAGEDSVSFTPAPAATMGSMGNVKGRGSSSDGDHNRYSRATARLTTAGRRTSFTKHSSTTTSIRRRVSTRGEIVFSGSRNLYRFTAEAMSMNESIVIAVVVDGTIIRWNSVAQSVTGYAPFEAIGKSVFDFIVSEDGRQHMRDTLAVAARFAGRWEQYNMRGLQEQRVFPFRQNAGLYQVGLALSVIPSNYAKTAEVLLLIGREGKYRAASTYAADVAKWLEGSLKPQLRQFQRRMVQIESHGWQLTAEDALQVRGNLDACMSMVEQFTKFSLLNMDVVSQSWRPVRVSALLRRFAVEAMAFARQQQHEYYCNIDLVEPKAEVFLDSPQVLAILRLLLGDALQCPNMGDDGNAIVVHAELRVTVVEPQDTNQVPLSIGSPVGRVSGGGSSAGGFAGLFAPPNMSSIAPPENHSSSSSAAAAHGLRNVVASPSGSAKPSYPVIHTPVSAVQSSSEAAPLIPSGVSLPHRPLPRGHSPPLHAQKSYQHHGSDTVLPNHSHDSPLVALVSEKAPGSGGNAQGGADGSPNSAAVWPTPGSTTSSGAGMRGLPSAPISNALTSTLRRIRFELRDDGPTIPSLRGHEAVASERTHDHASPESASVDDSAALNSTSPKSASCTSERVAGDGAGDGGGLSAGLEASRSFTFAAASARRGAELEQVEKILANLGGVVYGFTRPEVPGNVVRVELPLLVVPGSTDDGRDEENGGGGGGGGTAAPPSSATRTFTVIVADSNRLHQQQLCRVLWARQHAVVPVTSFRDLGRKLEMNTADILLIDPLHIDIASEDYESLLGDDPFDDIRVLSARLALVVMASDFSDWRVQKLLNRHAVVELPKVGSGALVHIAMQEAEQLVTEMRDEEERLDLIRRTFTNSSTERHKIGKRIGKGAFGDVFEVEDTLTGGKMAMKRMRLHDGLLADEVVQEILAMTTLTHENIIQYFYCEKESDTLLRLYMELAPGGTLRDKIRETPGVPLPFEEIVHHLSCICHGLAYVHEKSYVHGDLKTANLLLGTRNRTKIGDFGTAKHLAPHQLLYT-MVGTPQYMAPEVLTADVEQRLGYDFKADIWSLGCIVLEMATGSPPFAHMECAQGMGIIKYLTELTDTPDLSPLFSGNPLVYEFVKSCLDVDPQNRPTAQELL-HFDILEGAVASQRAERLVRRAEMLYKLNKYAAMRADGGGGGTGRNTSGSGGGRGGAARGGGHDGSEDSEEAEGDDGNHSSLYDSGVLFSSSDSTAYEEEYDDEDDYDENDELSEHDSAEDVMENDSVPREKRDRQHSPPTSSSPAFMPEGAK
4O27 Chain:B ((12-274))---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLE--PG-PLDETQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNEFVGTPFWMAPEVI-----KQSAYDSKADIWSLGITAIELARGEPPHSELHPMK----VLFLIPKNNPPTLEGNYS-KPL-KEFVEACLNKEPSFRPTAKELLKHKFILRNAKKTSYLTELIDR------------------------------------------------------------------------------------------------------------------------------------


General information:
TITO was launched using:
RESULT:

Template: 4O27.pdb
Alignment : align.pir
Tito was launched with SMD and SCWRL
Tito text output
Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 1349 -57707 -42.78 -221.10
target 2D structure prediction score : 0.52
Monomeric hydrophicity matching model chain B : 0.55

3D Compatibility (PKB) : -42.78
2D Compatibility (Sec. Struct. Predict.) : 0.52
1D Compatibility (Hydrophobicity) : 0.55
QMean score : 0.346

(partial model without unconserved sides chains):
PDB file : Tito_4O27.pdb:





(Unconserved sides chains are recalculated) :
Sequence: align-4O27-query.scw
PDB file : Tito_Scwrl_4O27.pdb: