Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence AVPTNPPDVPTNSPDVPTKPPGRISNTAAGFVNFFKKKASSSTPPPAECEYTVYRNQETDARRRKHSQEGTYSFSHHGKAAKNSKQNIFGVKVRFDRECRPYYSSKNQIAVIPGIHNDDVIQVDWERFDLHMR 5C5D Chain:A ((59-92)) -------------PKLYITIAGR-SNALSGFVDGFVKGATIACPPPSD-------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 5C5D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 84 1785 21.24 52.49 target 2D structure prediction score : 0.41 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 21.24 2D Compatibility (Sec. Struct. Predict.) : 0.41 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.370

(partial model without unconserved sides chains): PDB file : Tito_5C5D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5C5D-query.scw PDB file : Tito_Scwrl_5C5D.pdb: