Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPARGRSVNKGYPITDLVILAGGQARRMNGLNKLLQQFDSDTQLLKIHQKLKSSVSEIWVNSHRDYSIYQSIVPDIKCFQDDASGFFGPLMGMKSAWSHVKADYVLFIPCDVTYMPTQVVAKLHSALRKNKQAQAAYVSINGDALYPFCLLKRESLE-VLEQQIDKQQLSLKNCFKLLHAQVAIFQKQNLFFHSINSLDELQQYKQIKAFKEIFSTN 1E5K Chain:A ((10-191)) -----------------VVLAGGKARRMGGVDKGLLELNGKPLWQHVADALMTQLSHVVVNANRHQEIYQA--SGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDTPYIPPDLAARLN---HQRKDAPVVWVH-DGERDHPTIALVNRAIEPLLLEYLQAGERRVMVFMRLAGGHAVDFSDHKDAFVNVNTPEELARWQ------------

General information: TITO was launched using: RESULT: Template: 1E5K.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 934 -103678 -111.00 -572.81 target 2D structure prediction score : 0.55 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -111.00 2D Compatibility (Sec. Struct. Predict.) : 0.55 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.367

(partial model without unconserved sides chains): PDB file : Tito_1E5K.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1E5K-query.scw PDB file : Tito_Scwrl_1E5K.pdb: