Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKIWFAEYQKTGIPETVALPAENTSLVDIFERNFQKFGSRDAFIFMD--------KAMSFNELELASRKFATYLQNLGLAKGTRVAVMMPNVLQYPVVALAVLRAGLVLVNVNPLYTARELEHQLNDSGAEVLVIIENFASVYQSILGKTPVKHVVVASVGDMLGTLKGTLVNFVLRKVRKQIPAWNIPGHVKFNSALNKENPSNYKRPTLTLSDTAVLQYTGGTTGVSKGAELTHRNLVANLLQCDGIFQSKFGANDGAKGDRIVCALPLYHIFAFMVCAMYGMYKGQANILIPNPRDLPAVIKELRKYQPSFFPAVNTLFNALVNNEEF--KQLDHSNLKMAMGGGMAVLPSTAEAWKKITGTTII-------EGYGLSETSPVATANPPASTEFSGTIGIPLPLTEVAILD-DDGKEVPLGEQGEISIRGPQVMKGYWNRPDETAKVMTAD----GFFRTGDIGVMDSRGYVKIVDRKKDMILVSGFNVYPSEIEEVIAKHPKVLEVAAIGVPDEKSGEVPKLFIVKKDP---SLTTEEVLNFAKENLTGYKRPRYVEFMDELPKSNVGKILRKDLRKPV 3G7S Chain:A ((6-522)) ----------KIGFP---SLYYPKISLADRIDAAAEKFGEKTAIISAEPKFPSEFPESMNFLEICEVTKKLASGISRKGVRKGEHVGVCIPNSIDYVMTIYALWRVAATPVPINPMYKSFELEHILNDSEATTLVVHSMLYENFKPVLEKTGVERVFV--VGGEVNSLSEVMDS----------------GSEDFENV--KVNPE---------EDVALIPYTGGTTG-PKGVMLTHFNLAANALQLAV-------ATGLSHMDTIVGCMPMFHSAEFGLVNLMVTVGNE--YVVMGMFNQEMLAENIEKYKGTFSWAVPPALNVLVNTLESSNKTYDWSYLKVFATGAWPVAPALVEKLLKLAAEKCNNPRLRHNQIWGMTEACPMVTTNPPLRLDKSTTQGVPMSDIELKVISLEDGRELGVGESGEIVIRGPNIFKGYWKREKENQECWWYDEKGRKFFRTGDVGFIDEEGFLHFQDRV------------PFELEALLMKHEAVMDVAVIGKPD------PKAFIVLKPEYRGKVDEEDIIEWVRERIS-----REVEFVEELP----------------

General information: TITO was launched using: RESULT: Template: 3G7S.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2724 -4752 -1.74 -10.15 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -1.74 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_3G7S.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G7S-query.scw PDB file : Tito_Scwrl_3G7S.pdb: