Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTEGVGLPLWLLA-ELTYRCLLQCPYCSNPLDYAQH-----KNELTT-QEWFDVFDQARQMGAVQLGFSGGEPLVRQDLEQLVAHAHQLGFYTN--LVTSGMGLTEQRISHLKQAGLDHIQISFQASDPVLNDALAGSKHAFEQKYEMCRLVKKYDYPMVLNFVIHRHNIDQIDKIIELCLELNADTVELAICQFY------GWAFLNRQGLLPTQEQLIRAERITNEYREKLKAQNHPCKLIFVVPDYYEERPKACMNGWGKIFFTVAPDGMALPCHAARQLPISFPNVREQSLSRIWYESTGFNRFRGDAWMPEGCRSCPDKDRDFGGCRCQAYMLTGDASNADPVCGKSPYHQFIEQARAESEIDSSLEKLVFRNSRNSKQFTVQQNIPVQNIVDD 2FB2 Chain:A ((5-207)) IKDKLGRPIRDLALSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGL-LLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGIND--DQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2FB2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 847 6036 7.13 32.11 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 7.13 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.419

(partial model without unconserved sides chains): PDB file : Tito_2FB2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2FB2-query.scw PDB file : Tito_Scwrl_2FB2.pdb: