Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIYRLSMSLIANTTVVRGRFLDIQQTVSEPTDIPNQVRYLEDGVL-ISEHGKIKWFGAWEDAQQH---------LPAGV-EVQHYPEQLIVPGFIDTHIHFPQTEMVGAYGE-QLLSWLNTYTFPTEIQFQDKTYASEIAQFFVQELLKHGTTTALVFCTVHPESVDALFEAAERVQMRLIAGKVLMDRNA--PEALCDTPETAYSNTKALIEKWHGKG--RALYAITPRFAPTSTPEQLERAGQLKQEFPDVYVHTHLSENKDEIAWVKSLFPEQAGYLDVYQHYGLTGKRSVFAHCVHLEDEEWQCMHDTQSAIAFCPTSNLFLGSGLFPLKKTWEKQVKVGLGTDIGAGTSFSLLQTVNEAYKV------QQLQGDKLSAYEALYHATLGGAKALDLQDQLGNFNIGKEADFVVLNLKP--TALQELRQTKSKSVEDSLFALFT-LGDDRNIEATYIYGNRAYQKETAK 2UZ9 Chain:A ((34-469)) ---------------IFRGTF--VHSTWTCPMEV------LRDHLLGVSDSGKIVFL---EEASQQEKLAKEWCFKPCEIRELSHH--EFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFAEEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEYK-ETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKT-RDLHIQSHISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAHCPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNEKSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDISEAVIQKFLYLGDDRNIEEVYVGGKQV-------

General information: TITO was launched using: RESULT: Template: 2UZ9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2513 41242 16.41 100.35 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 16.41 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.470

(partial model without unconserved sides chains): PDB file : Tito_2UZ9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2UZ9-query.scw PDB file : Tito_Scwrl_2UZ9.pdb: