Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MYKVIAGSWTKFKEDAKYIREQVFIQEQGIAHEDEWDDFDSIAMHFMVYDEGQPIATARLLPQHS----VGRVAVLMLYRKQGIGKILMQHIIEYARQHKLPYLKLSAQTYVTAFYEALGFKVQGEVYQDCGIPHIDMTLALS 5JQ4 Chain:A ((15-144)) -------------EDCFYIRKKVFVEEQGIPEESEIDEYESESIHLIGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAKDEGFYVATMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLT

General information: TITO was launched using: RESULT: Template: 5JQ4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 475 -32034 -67.44 -254.24 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -67.44 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_5JQ4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5JQ4-query.scw PDB file : Tito_Scwrl_5JQ4.pdb: