Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIDLYYWGTPNGHKITIALEEMGLDYTLYPINILENDQFQPDFLKISPNNKIPAIVDQ--DGPRGEPISVFESGAILQYLGRKTGLFYPTDEQERVEVEQWLMWQMGGLGPMLGQNHHFNRFAPEKIPYAIDRYVNETKRLYGVLNKQLIRQKFVAG-EYSIADMAILPWILRYEWQGIQLEDYPYVQEYIVRLTARPAVQKALSIKVI 4L8E Chain:A ((29-229)) -IDLYYAPTPNGYKITLFLEEVGLPYTIHPIDISAGDQFKPEFLAIAPNNKIPAIVDHQPDG-GGEAISIFESGAILLYLANKTGRFLSKDTRERTEQLQWLFWQVAGFGPMLGQNHHFNRYAPEVVPYAIKRYTEESQRLYKVLNTQLEKTPYLGGNEYSIADIAVYPWAKCYEHQKINLEDYPAVKKWLEKIQQRPATQAA------

General information: TITO was launched using: RESULT: Template: 4L8E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 905 -25048 -27.68 -126.50 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.86 3D Compatibility (PKB) : -27.68 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.86 QMean score : 0.550

(partial model without unconserved sides chains): PDB file : Tito_4L8E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4L8E-query.scw PDB file : Tito_Scwrl_4L8E.pdb: