Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVYYPQPVDNLVNKRSCKRRRYITMKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQEDPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGKGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYGNAGKFAEVWMDGARGEG--AQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKV------------NLDKLG--TEAE-LNYLQHGDPSGTIFSI-GEADVSIRPGWFYH--EDQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERPYEFATYRNELYKEDLALGAEVSGPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKTPGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSRSSSSLEAKISIQPGTGVHGVAYQDEIYALAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS 4ZRX Chain:A ((31-458)) ---------------------------------VPTPQQYAWQQMELTAFLHFGINTFTGREWGDGKEDPALFNPSELDAEQWVRTLKEAGFKMVLLTAKHHDGFCLWPTATTKHSVASSPWKNGQGDVVKELRAACDKYDMKFGVYLSPWDRNAECY--GDSPRYNDFFIRQLTELLTN-----YGEVHEVWFDGANGEGPNGKKQVYDWDAFYQTIQRLQPKA-VMAIMGDDVRWVGNEKGVGRETEWNATVLTPGIYARSQENNKRLGVFSKAEDLGSRKILEKATELFWYPSEVDVSIRPGWFYHAEEDGKVKSLKHLSDIYFQSVGYNSVLLLNIPPDRRGLIHEADIKRLKEFADYRQQTFADN-------------------RVKNGRKYWSTTSGGEAVYALK----SKSEINLVMLQEDITKGQRVEAFTVEALTDNGWKEVGKGTTIGYKRMLRFPAVNANKLRVRIDECRLTAYVSQVAAY---------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 4ZRX.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2284 6190 2.71 15.17 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 2.71 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.429

(partial model without unconserved sides chains): PDB file : Tito_4ZRX.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4ZRX-query.scw PDB file : Tito_Scwrl_4ZRX.pdb: