Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSYSASYLPRMQQNLTLLQHYHENKENCMSFSMTKLSAALLLTSSLVGCAAVVKTPYQAPAVQVPGSFQYDKAKAKT---ASVEQYSDHWWTLFGDAQLNQLVTNVLERNSDLAVAGITLKQARLQADLTANKQGLRTSSSVSTGHSFDLNSGDDSAKG---LSMSAGVS-----YELDLFGKLARQTEASKWEALATEQDLQSTGQSLIATTAKLYWQLGYLNERYATAQQSLATSQKLYQLVQTQYKAGAVSGLDLTQAEQSVQSQKASLSQIEQQLVETRTAIAVLLHEPVQQLNIQEPQRLPRTALPAIGAGLPADILSRRPDLQAAELRLRKALATKDATKASYYPSISLTSSLGSSSTSLTELLR--NPALTLGASLSLPF---------LQYNDIKKDIAISNLDYEKAIIQYRQTLYQAFADVENALSSRTELDKQVALQERNVELAEKTERLTEVRYRYGAVALKTLLDAQQTTRTARLSLVETKQSQYNAYVTLMQALGGSPVKELPQ 1WP1 Chain:A ((7-449)) ---------------------------------------------------------YQRPEAPVAAAYPQGQAYGQNTGAAAVPAADIGWREFFRDPQLQQLIGVALENNRDLRVAALNVEAFRAQYRI--QRADLFPRIGVDGSGTRQRLPGDLSTTGSPAISSQYGVTLGTTAWELDLFGRLRSLRDQALEQYLATEQAQRSAQTTLVASVATAYLTLKADQAQLQLTKDTLGTYQKSFDLTQRSYDVGVASALDLRQAQTAVEGARATLAQYTRLVAQDQNALVLLLGSGIPA-NLPQGLGLDQTLLTEVPAGLPSDLLQRRPDILEAEHQLMAANASIGAARAAFFPSISLTANAGTMSRQLSGLFDAGSGSWLFQPSINLPIFTAGSLRASLDYAKIQKDINVAQ--YEKAI----QT---AFQEVADGLAARGTFTEQLQAQRDLVKASDEYYQLADKRYRTGVDNYLTLLDAQRSLFTAQQQLITDRLNQLTSEVNLYKALGGG-------

General information: TITO was launched using: RESULT: Template: 1WP1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1475 30890 20.94 73.37 target 2D structure prediction score : 0.65 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 20.94 2D Compatibility (Sec. Struct. Predict.) : 0.65 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.340

(partial model without unconserved sides chains): PDB file : Tito_1WP1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1WP1-query.scw PDB file : Tito_Scwrl_1WP1.pdb: