Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MQDIIAYFIQNLTALYIAVALVSLCIGSFLNVVIYRTPKMMEQDWQQECQMLLNPEQPIIDHEKLTLSKPASSCPACQQPIRWYQNIPVISWLTLRGKCGHCQHPISIRYPAVELLTMLCSLVVVMVFGPTIQMLFGLVLTWVLIALTFIDFDTQLLPDRFTLTLAALGLGINTFNIYTSPNSAIWGYLIGFLCLWIVYYLFKVITGKEGMGYGDFKLLAALGAWMGPLMLPLIVLLSSLLGAIIGIILLKLRNDNQPFAFGPYIAIAGWVAFLWGDQIMKIYLGG 3S0X Chain:A ((511-607)) -----------------------------------------------------------------------------------------------------------------------------------------------LIIASVQD----EIEDYIWIFLAVFGV---LFAIYSSITLLDYSILINSISGFVICFILGYMMFLSGIGGGDGKMLIGLGALVPKFQMPIYTSLGTLL---------------------------------------------

General information: TITO was launched using: RESULT: Template: 3S0X.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 234 -42085 -179.85 -462.47 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : -179.85 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.137

(partial model without unconserved sides chains): PDB file : Tito_3S0X.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3S0X-query.scw PDB file : Tito_Scwrl_3S0X.pdb: