Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLDLFSPEPCSNLLPYDGVVQDYGCILTVEEAEQYFHYLYHHLAW---RHDEAKLYGKHFITPRKVAWYGDEHYRYKYSGVFRDSLPWDKALAQLKQQVEQILSEKFNSCLANLYEDGTQGMAWHSDSDVSLARTTTIASLSFGAMRKFSFRHIQTKEK--------VEMWLQPGQLIVMRGETQQYWQHRLNRSTKILQPRINLTFHQFKFS 3RZG Chain:A ((11-204)) -----------------EGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWHSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFVLINRYKDGSDHICEHRDDERDLAPGSPIASVSFGASRDFVFRHKDSRGKSPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKI---

General information: TITO was launched using: RESULT: Template: 3RZG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 743 16281 21.91 88.96 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain A : 0.72 3D Compatibility (PKB) : 21.91 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.72 QMean score : 0.268

(partial model without unconserved sides chains): PDB file : Tito_3RZG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3RZG-query.scw PDB file : Tito_Scwrl_3RZG.pdb: