Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKITALLFALCATVTHAELQTLDNDALQAINGQAGADLSLMLNLNQTSNGIFDNGSGGVCENVEFCHIGLAINKRFVQADTTKPSGWAENSDSGNKLWLVFKGVQGTLNIQKMGLDGADLKYLDKSNTEIIKLAIQLSFSAAQPILIRNFGFNALSIEQDNFTSSTTTQGSSANMYDYAYFKKPTYAATANSANQQVATATPSAYDYGRETGFMGLMMNGNMAIQGKVMVFSCDGSHPRC 2QLT Chain:A ((85-201)) --------------------------------------------------------------------------------------------------------------IAKFAPDFADEEYVNKLEGEIPEKYGEHSIEVPGAVKLCN-ALNALPKEKWAVATSGT-RDMAKKWFDILKIKRPEYFITANDVKQ--GKPHPEPYLKGRNG--LGFPINEQDPSKSKVVVFE--------

General information: TITO was launched using: RESULT: Template: 2QLT.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 347 -3334 -9.61 -28.50 target 2D structure prediction score : 0.34 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -9.61 2D Compatibility (Sec. Struct. Predict.) : 0.34 1D Compatibility (Hydrophobicity) : 0.65 QMean score : -0.075

(partial model without unconserved sides chains): PDB file : Tito_2QLT.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2QLT-query.scw PDB file : Tito_Scwrl_2QLT.pdb: