Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQRDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFIQNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQ------AEFFSFEACEYRRHFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFA---YG------DDAYLRKL--KANVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPA------------FGKHNILNALGVIAVAYFEKLDLKEVAEEMLTFPGVKRRFSE-----KIVADMTVVDDYAHHPAEIKATIDGARQKYPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGAKIKKGGEV--IKENNVSPLLDYHDAV------VIFMGAGDVQKFEQAYEKLLSSTTKNVL 1GQY Chain:A ((22-475)) --------HFIGIGGAGMSGIAEILLNEGYQISGSDIADGVVTQRLAQAGAKIYIGHAEEHIEGASVVVVSSAIKDDNPELVTSKQKRIPVIQRAQMLAEIMRFRHGIAVAGTHGKTTTTAMISMIYTQAKLDPTFVNGGLVKSAGKNAHLGASRYLIAEADESDASFLHLQPMVSVVTNMEPD-------------DFEKMKATYVKFLHNLPFYGLAVMCADDPVLMELVPKVGRQVITYGFSEQADYRIEDYEQTG------------FQGHYTVICPNNERINVLLNVPGKHNALNATAALAVAKEEGIANEAILEALADFQGAGRRFDQLGEFIRPNGKVRLVDDYGHHPTEVGVTIKAAREGWGDKRIVMIFQPHRYSRTRDLFDDFVQVLSQVDALIMLDVYAAGEAPIVGADSKSLCRSIRNLGKVDPILVSDTSQLGDVLDQIIQDGDLILAQGAGSVSKISRG----LAESWKN--

General information: TITO was launched using: RESULT: Template: 1GQY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2239 -18827 -8.41 -46.49 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : -8.41 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.438

(partial model without unconserved sides chains): PDB file : Tito_1GQY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GQY-query.scw PDB file : Tito_Scwrl_1GQY.pdb: