Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREGFVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLGIAIISTSEGVVTDKEAREKNIGGEVIAYVW 4PDB Chain:A ((27-155)) ---TDPIADMLTRIRNANMVRHEKLEVPASKIKKEIAELLKREGFIRDVEYIEDNKQGILRIFLKYGANNERVITGLKRISKPGLRVYAKADEVPRVLNGLGIALVSTSKGVMTDKDARQLQTGGEVVAYVW

General information: TITO was launched using: RESULT: Template: 4PDB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 585 -74171 -126.79 -574.97 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.94 3D Compatibility (PKB) : -126.79 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.94 QMean score : 0.642

(partial model without unconserved sides chains): PDB file : Tito_4PDB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4PDB-query.scw PDB file : Tito_Scwrl_4PDB.pdb: