Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIELNQVRKEITCDM--KLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPE---LPGTMYVEDKEMPHLRKGTIIKIDQEDQNGGKLYGNHA 2F9H Chain:A ((6-119)) ----QATVTEIGKHA-IDDSEKMIILFGETATDTLKQHAV-IQSFPEKDQVTLAEGDHLKIGDTNYTITKVGSFANSNLQSIAHSTLIFADAPTDEDDVIRNGVYLTPHQLPKITIGTTI-----------------

General information: TITO was launched using: RESULT: Template: 2F9H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 485 -20568 -42.41 -188.70 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -42.41 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.518

(partial model without unconserved sides chains): PDB file : Tito_2F9H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2F9H-query.scw PDB file : Tito_Scwrl_2F9H.pdb: