Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEARVIGLEKLGKHDVELVGGKNSSLGEMISHLSNAGVSVPGGFATTADAYREFLDQSG-LNARIQAE-------LAELN-------VDDVNALAETGAKIRQ-WIVETPLTPGLEQEIREAFAALSNGNPDIA-----------------------------------VAVRSSATAEDLPDAS--FAGQQETFLNIRGI-----DNVLIAVKEVFASLFNDRAIAYRVHQGFEHSLVALSAGVQRMV---RSETGAAGVMFTLDTESGFRDVVFITASYGLGEMVVQGAVNPDEFYLSKPLLNAGKHAVLRRNLGSKHQKMIYGEE--GSAGKSVVVVDVEKQERQQFALNDHELQELAKQ----ALIIEKHYGAPMDIEWAKDGDDGQIYIVQAR------PETVKSRQNVGTMERYLLKQKGTVLCEGRSI---------------GQRIGS----------GKVRIV-NSIKEMDKVQDGDVLVSDMTDPDWEPVMKRAAAIITNRGGRTCHAAIITRELGVPAIVGCGNATEVLTDGQEVTV-----SCAEGD-------TGFIYEGALDFEVQRNSIE-SMPKL--------SFKIMMNVGNPDRAFDFAQIPNEGIGLARLE---FIINRMIGVHPKALLNIESLPRETRAAVMTRTAGYASPVEFYVEKLVEGIATLAAAFADKPV--IVRMSDFKSNEYANLIG-------GKLYEPEEENPMLGFRGASRYISDNFRDCFELECRALKK----VRDEMGLTNI-QIMIPFVRTVSEAKRV----IELLAQNGLKRGEN-GLKVIMMCELPTNALLAEQFLEHFDGFSIGSNDLTQLTLGLDRDSG------------IVSHLFDERD-AAVKALLSMAIHACR--KAGKYVGICGQGPSDHPDLAKWLMEQGIESVSLNPDSVLDTWFFLAEEKIKQI 1KC7 Chain:A ((17-855)) -----------------LLGGKGCNLAEM----TILGMPIPQGFTVTTEACTEYYNSGKQITQEIQDQIFEAITWLEELNGKKFGDTEDPLLVSVRSGARASMPGMMDTILNLGLNDVAVEGFAK-KTGNPRFAYDSYRRFIQMYSDVVMEVPKSHFEKIIDAMKEEKGVHFDTDLTADDLKELAEKFKAVYKEAMNGEEFPQEPKDQLMGAVKAVFRSWDNPRAIVYRRMNDIPGDW-GTAVNVQTMVFGNKGETSGTGVAFTRNPSTG--------------------------------------------------EKGIYGEYLINAQGEDVVAGVRTPQPITQL---ENDMPDCYKQFMDLAMKLEKHFRDMQDMEFTIE--EGKLYFLQTRNGKRTAPAALQIACDL-VDEGMITEEEAVVRIEAKSLDQLLHPTFNPAALKAGEVIGSALPASPGAAAGKVYFTADEAKAAHEKGERVILVRLETSPEDIEGMHAAEGILTVRGGMTSHAAVVARGMGTCCVSGCG---EIKINEEAKTFELGGHTFAEGDYISLDGSTGKIYKG--DIETQEASVSGSFERIMVWADKFRTLKVRTNADTPEDTLNAVKLGAEGIGLCRTEHMFFEADRIMKIRKMIL----SDSVEAREEALNELIPFQKGDFKAMYKALEG-RPMTVRYLDPPLHEFVPHTEEEQAELAKNMGLTLAEVKAKVDELHEFNPMMGHRGCRLAVT--YPEIAKMQTRAVMEAAIEVKEETGIDIVPEIMIPLVGEKKELKFVKDVVVEVAEQVKKEKGSDMQYHIGTMIEIPRAALTADAIAEEAEFFSFGTNDLTQMTFGFSRDDAGKFLDSYYKAKIYESDPFARLDQTGVGQLVEMAVKKGRQTRPGLKCGICGEHGGD-PSSVEFCHKVGLNYVSCSP------------------

General information: TITO was launched using: RESULT: Template: 1KC7.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3850 153775 39.94 225.48 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 39.94 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.316

(partial model without unconserved sides chains): PDB file : Tito_1KC7.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1KC7-query.scw PDB file : Tito_Scwrl_1KC7.pdb: