Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSDVIKDLSELRLSYEQGELYETQVASNPHEQFLGWFNHALAANLHE-PYAMSLATAS-ASGRPHVRTVLLRGATEAGYDFYTNY-DSQKGIDLAENPYAELLFYWPSLERQVRVGGHVVKIPEQESTDYYHKRPRDSQIAAYISTPQSGKIESRELLQQRFQDLQQQVQSHEVLDKPEFWGGYRLQPDYYEFWQGRPNRLHDRLSYEKI--DGQWTLHRLMP 1CI0 Chain:A ((24-228)) -----------------FTLNEKQLTDDPIDLFTKWFNEAKEDPRETLPEAITFSSAELPSGRVSSRILLFKELDHRGFTIYSNWGTSRKAHDIATNPNAAIVFFWKDLQRQVRVEGITEHVNRETSERYFKTRPRGSKIGAWASR-QSDVIKNREELDELTQKNTERFKDAEDIPCPDYWGGLRIVPLEIEFWQGRPSRLHDRFVYRRKTENDPWKVVRLAP

General information: TITO was launched using: RESULT: Template: 1CI0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 872 14331 16.43 71.65 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.75 3D Compatibility (PKB) : 16.43 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.75 QMean score : 0.433

(partial model without unconserved sides chains): PDB file : Tito_1CI0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1CI0-query.scw PDB file : Tito_Scwrl_1CI0.pdb: