Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSAAPRIGILGAGGRMGRTLIQAVQQAGYQLAAAVERPESSLVGTDAGELAGIGSVGVKVSGSLADVLKDCDVIIDFTAPAATAQHLKLCREAGVAMVIGTTGMSDEQKAELDEAATHIPVVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRHKVDAPSGTALMMGEAIADTLGRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMNFAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV 3QY9 Chain:A ((3-243)) ---SMKILLIGYGA-MNQRVARLAEEKGHEIVGVIENTPK---------------TPYQQYQHIADV-KGADVAIDFSNPNLLFPLLD--EDFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDD-FDIELTEAHHNKKVDAPSGTLEKLYDVIV-SLKENV--TPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL--------

General information: TITO was launched using: RESULT: Template: 3QY9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1175 -162445 -138.25 -679.68 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.76 3D Compatibility (PKB) : -138.25 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.76 QMean score : 0.571

(partial model without unconserved sides chains): PDB file : Tito_3QY9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QY9-query.scw PDB file : Tito_Scwrl_3QY9.pdb: