Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MHLNSSIDKKMTTLNILFKTTSLCLAMALLVGCNDNDDNDSSTPAPRSNQTVNILAFNDFHGNLEPPKRYVEAANPNDASQTVRIPVGGVSYFADAIKKLKAQNPNNVVVSAGDLISASPLTSSLFLDEPTIEVMNDIQIDFNAVGNHEFDRGTDELRRLQNGGCQQYTSTAPCQINKNFSGAKFNFLAANVAMKNDTSKTIFPAYKVKTYGGIPVAFIGLTLKATPSIVSAAGIKDVEFRDEADTVNALIPELQK-QGIEAIVVVVHEGAAPSTKLNQKTCDGLSGPILGILDRLNPA--VDIVVSGHTHQSYIC---------DYATKNPAKP-----FLLTSAGQYGTLITDIKVGLDGKTGDIIKKDAKQIPVQSEAYTSGTTTVSLTDLYQ-KFSKTPSIEAILDKYRQ--------AVTTISGRVVGTSTAVVSRTQVESGESPLGDMIADAQQAAALQASNQGSDFTLMNPGGVRADLLINSSNQITFGDIFAVQPFGNSIVTLSLTGKQIRDVLEQQWSGANANSPRILQPSKELSYQYAANTSVSP--RASNIMVAGSPLVDTKVYRVTVNSFLADGGDNFTVLKEGQNRVGGGQ-DIDALESYVAQNSKDSPLIIPATTRIKVIK 1OI8 Chain:A ((37-511)) --------------------------------------------------------------------------------------------LVDGIRKEVAAEGGSVLLLSGGDINTGVCESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQE-------------------KWAKFPLLSANIYQKS-TGERLFKPWALFKRQDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGE------HGSNAPGDVEMARALPAGSLAMIVGGHS-QDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVG--RADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEG------DRDKVRFVQTNMGRLI------LAAQMDRTGADFAVMSGGGIRDSI---EAGDISYKNVCKVQPFGNVVVYADMTGKEVIDYL---------TAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYI---QKSSPL------------

General information: TITO was launched using: RESULT: Template: 1OI8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2347 -14884 -6.34 -33.37 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -6.34 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.427

(partial model without unconserved sides chains): PDB file : Tito_1OI8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OI8-query.scw PDB file : Tito_Scwrl_1OI8.pdb: