Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTQTSLSQSPNDTTSSQDVIEIKTVTRSVGRKATITKEELFQAALNLIGPQKSIASLSLREVAREAGIAPNSFYRHFKDIDELAISLIDRAGIVLRKIIRQARLRASLQDSIIRSSVEIFLQQLDADEGNLSLFLREGFTGSASYKAAVDRQLNFFQQELQEDLIRLERLNNNHLYHPELVAKAITQLVFHMGAKVIDLPIDQRAEVAEQTMIMIRMILEGARHLDEAKIR 3HTI Chain:A ((30-83)) ------------------------------------RQRIIDAAIRVVG-QKGIAGLSHRTVAAEADVPLGSTTYHFATLDDLMVAALRQA--------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3HTI.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 186 -33031 -177.59 -611.69 target 2D structure prediction score : 0.72 Monomeric hydrophicity matching model chain A : 0.60 3D Compatibility (PKB) : -177.59 2D Compatibility (Sec. Struct. Predict.) : 0.72 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.844

(partial model without unconserved sides chains): PDB file : Tito_3HTI.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3HTI-query.scw PDB file : Tito_Scwrl_3HTI.pdb: