Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNSLKNDKIGEIFDYQIFKEGIVSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDPRL--HVAQALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPFQEYLKEELGV------DVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSMTVVEL 1G5C Chain:A ((21-163)) -----------------------------------------------LKHSPKLCIITCMDSRLIDLLERALGIGRGDAKVIKNAGNIVDDGVIRSAAVAIYALGDNEIIIVGHTDCGMARLDEDLIVSRMR-ELGVEEEVIENFSIDVLNPVGDEEENVIEGVKRLKSSPLIPESIGVHGLIIDINTGRL-----

General information: TITO was launched using: RESULT: Template: 1G5C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 529 -10615 -20.07 -78.63 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : -20.07 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.548

(partial model without unconserved sides chains): PDB file : Tito_1G5C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1G5C-query.scw PDB file : Tito_Scwrl_1G5C.pdb: