Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLFSGSSMSEQIFIQGPVGKIELFVDRPEGEIKGFAVVCHPHPLQGGTPQHKVPALLTQIFNEYGCIVYRPSFRGLGGSEGVHDE--GHGETEDILAVIEHVRKLHAGLPFYAGGFSFGSHVLAKCHAQLSPELQPVQLILCGLPTATVVG--L----------------R------------HY----K--T--PEIQGDILLIHGEQDDITLLSDAIEWAKP-QKHPITILSGANHFFTGYL-KQLRQIITRFIIMK 3QM1 Chain:A ((19-265)) -----FQGMATITLERDGLQLVGTREEPFGEIYDMAIIFHGFTANRN---TSLLREIANSLRDENIASVRFDFNGHGDSDGKFENMTVLNEIEDANAILNYVKTDPHVRNIYLVGHAQGGVVASMLAGLYPD--LIKKVVLLAPAATLKGDALEGNTQGVTYNPDHIPDRLPFKDLTLGGFYLRIAQQLPIYEVSAQFTKPVCLIHGTDDTVVSPNASKKYDQIYQNSTLHLIEGADHCFSDSYQKNAVNLTTDFLQ--

General information: TITO was launched using: RESULT: Template: 3QM1.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1129 -23964 -21.23 -116.90 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -21.23 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_3QM1.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3QM1-query.scw PDB file : Tito_Scwrl_3QM1.pdb: