Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEGVRDECRRLSGKEAY-AFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTFDLGKACDMFEVNILGMMVLTQKFAIDMAERR--QGHIINIASMAGK--MATAKSTVYSATKFAVLGFSNALRLELK--PLGVAVTTVNPGPIETDF---FDKADPSGSYLEKVGQIVLEPAKLAKMIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK 1XG5 Chain:A ((30-264)) --WRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYE---CLKPEDVAEAVIYVLSTP-----------------------------------

General information: TITO was launched using: RESULT: Template: 1XG5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1181 -59551 -50.42 -268.25 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -50.42 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.541

(partial model without unconserved sides chains): PDB file : Tito_1XG5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XG5-query.scw PDB file : Tito_Scwrl_1XG5.pdb: