Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEVFDMSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQEYDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQYL 3DIE Chain:A ((8-106)) ---------VTDADFDSKVESGVQLVDFWATACGPCKMIAPVLEELAADY-EGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL

General information: TITO was launched using: RESULT: Template: 3DIE.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 240 -35671 -148.63 -360.31 target 2D structure prediction score : 0.68 Monomeric hydrophicity matching model chain A : 0.83 3D Compatibility (PKB) : -148.63 2D Compatibility (Sec. Struct. Predict.) : 0.68 1D Compatibility (Hydrophobicity) : 0.83 QMean score : 0.543

(partial model without unconserved sides chains): PDB file : Tito_3DIE.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DIE-query.scw PDB file : Tito_Scwrl_3DIE.pdb: