Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKKIVKDIL-FLSQVSQPAS---QEDLYLARDLQDTLLANRDTCVGLAANMIGVQKRVIIFNLGL---VPVVMFNPVLLSFEGSYEAEEGCLSLVGVRS-TKRYETIRLAYRDSKWQEQTITLTGFPAQICQHELDHLEGRII 1XEO Chain:A ((1-142)) SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYA--EEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLF

General information: TITO was launched using: RESULT: Template: 1XEO.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 626 9512 15.19 70.99 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 15.19 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.484

(partial model without unconserved sides chains): PDB file : Tito_1XEO.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1XEO-query.scw PDB file : Tito_Scwrl_1XEO.pdb: