Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence WFFGAIRRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLD-----GAVVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHY 1A08 Chain:A ((9-91)) WYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYY

General information: TITO was launched using: RESULT: Template: 1A08.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 267 -6532 -24.46 -83.74 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.84 3D Compatibility (PKB) : -24.46 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.84 QMean score : 0.655

(partial model without unconserved sides chains): PDB file : Tito_1A08.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1A08-query.scw PDB file : Tito_Scwrl_1A08.pdb: