Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAQMKTNASAKKAVNSPNHIYDTFIVGAGISGIAAAIRLDQVGYTNYKIIEKAGRVGGTWRENTYPGCGCDVPSALYSYSFAP----SAKWGHLFARQPEILSYLEDVSNEFNITSKIEFYNELLNAAWDESRHLWVLDTTT-GQYLSRTVIFATGPITEAQIPRLEGLDTFTGEMFHSAKWNHD-YDLTGKRIAVIGTGASAIQFVPQIQPKAKELFVFQRTAPWVLPKPDTDLGELSKSI----I-------AKYPAIQASWRKSV--A--------LTLNA--------INFGL---RN-PLALKPVNVLGKQLLKLQIADPELRKNVTPN-FDIGCKRILFANNYYPALQAPNTTLIP---HGLVKVEGNTVIAANGERHEVDVIIWGTG-FEV--SHPPIGKRVFNEKGQRLNDLWKNSSPEAYLGTNIENVPNAFLVLGPNVLVY-DSFIGLAEAQLDYIVDGLLKIKNKGISKLNVKADVIKKHNDLVQKHLQTTVFNSGGCKSYYLDA----NGRNFAAWPWSLKKLKQRLKKLDLKDYEVTYQMSKTH 2YLR Chain:A ((10-537)) --------------RRQPPEEVDVLVVGAGFSGLYALYRLREL-GRSVHVIETAGDVGGVWYWNRYPGARCDIESIEYCYSFSEEVLQEWNWTERYASQPEILRYINFVADKFDLRSGITFHTTVTAAAFDEATNTWTVDTNHGDRIRARYLIMASGQLSVPQLPNFPGLKDFAGNLYHTGNWPHEPVDFSGQRVGVIGTGSSGIQVSPQIAKQAAELFVFQRTPHFAVPARNAPLDPEFLADLKKRYAEFREESRNTPGGTHRYQGPKSALEVSDEELVETLERYWQEGGPDILAAYRDILRDRDANERVAEFIRNKIRNTVRDPEVAERLVPKGYPFGTKRLILEIDYYEMFNRDNVHLVDTLSAPIETITPRGVRTSER-EYELDSLVLATGFDALTGALFKI--DIRGVGNVALKEKWAA-GPRTYLGLSTAGFPNLFFIAGPGSPSALSNMLVSIEQHVEWVTDHIAYMFKNGLTRSEAVLEKEDEWVEHVNEIADETLYP--MTASWYTGANVPGKPRVFMLYVGGFHRYRQICDEVAAKGYE---------

General information: TITO was launched using: RESULT: Template: 2YLR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2656 20094 7.57 42.12 target 2D structure prediction score : 0.62 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : 7.57 2D Compatibility (Sec. Struct. Predict.) : 0.62 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.457

(partial model without unconserved sides chains): PDB file : Tito_2YLR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2YLR-query.scw PDB file : Tito_Scwrl_2YLR.pdb: