Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAAKRTDELIPLCHPLPIYRADVEYELEHDFVKIIAAVETIGPTGVEMEALTAASLAGLTIYDMLKPHCEPEELWMDQCKLLKKKGGKSHFKRVLRQPVSAAVIVLSDTVAAGRKPDTAGKSVVETLTEAGFDPIHYQILPDEADDLKELVLELT-KSYACIMTVGGTGIGKRDITVDTLEPLLERKLDGLMEAARSFGQKRTPYAAMSRGVAGFIDRSLVVALPGSRGGASESMAAILPALVHIFDVCRDLPHPGGYE 3PZY Chain:A ((7-160)) -------------------------------------------------------------------------------------------------TRSARVIIASTRASS----DRCGPIITEWLAQQGFSSAQPEVVADG-SPVGEALRKAIDDDVDVILTSGGTGIAPTDSTPDQTVAVVDYLIPGLAEAIRRSGLPKVPTSVLSRGVCGVAGQTLIVNLPGSPGGVRDGLGVLAGVLDHALDQLAGK-------

General information: TITO was launched using: RESULT: Template: 3PZY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 818 -50125 -61.28 -336.41 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : -61.28 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_3PZY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3PZY-query.scw PDB file : Tito_Scwrl_3PZY.pdb: