Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MCRLRERTRMTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKD---KGKYYTIGGAIQVNEKTEDAVVREVREELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDAPLTMQEDEKSQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE 3ID9 Chain:B ((22-153)) -----------------------MQVRVTGILIEDEKVLLVKQKVANRDWSLPGGRVENGETLEEAMIREMREETGLEVKIKKLLYVCDKPD----ASPSLLHITFLLERIE----------PIHDVQMVPINELSYYGFSET-FINLISGGLANAG------

General information: TITO was launched using: RESULT: Template: 3ID9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 492 -10604 -21.55 -91.41 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain B : 0.73 3D Compatibility (PKB) : -21.55 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_3ID9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ID9-query.scw PDB file : Tito_Scwrl_3ID9.pdb: